Principal Carelon Research Biostatistician Elevance HealthPrincipal Carelon Research BiostatisticianNewton, MassachusettsThis researcher partners with investigators, research sponsors, academic institutions, and cross-functional project teams to design studies, develop statistical methodologies, oversee analytical execution, and communicate scientific findings that advance externally funded clinical research programs. The Principal Carelon Research Biostatistician is responsible for serving as the statistical lead for complex clinical research studies and represents an analytical thought leader across Carelon Research's clinical research portfolio.
Principal Scientist, Systems And Disease Biology SanofiPrincipal Scientist, Systems And Disease BiologyCambridge, MA$122.25–$176.58 / hourD. in systems biology, computational biology, biostatistics, or related quantitative field with proven experience in a relevant disease area (Immunology, Neurology or Oncology) OR PhD in biological sciences, biomedical sciences, immunology, neuroscience, oncology or in a related disease area and proven advanced track record of data analytics, ML/AI, or computational biology. Leading projects involving internal experiment design and data analytics as well as outsourcing of established workflows and/or complex follow-up mechanistic assays (organoid, CRISPR, proteomics).
Principal Scientist SanofiPrincipal ScientistWaltham, MA$122.25–$176.58 / hourThe Genomic Medicine Unit (GMU) CMC group at Sanofi is dedicated to the establishment of best-in-class manufacturing platforms to support development of life-changing advanced cell and gene therapy products, including recombinant AAV vectors, lentiviral vectors and cell therapy products. Main responsibilities: Lead scale-up activities from bench scale to pilot scale (200L-2000L), applying engineering principles (mixing, mass transfer, shear stress, dissolved oxygen control) to ensure process comparability at large scale.
Principal Scientist, Computational Protein Design ModernaTXPrincipal Scientist, Computational Protein DesignCambridge, MassachusettsWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. This individual will work in close partnership with structural biology, directed evolution, immunology, translational science, and program teams to advance platform innovation and therapeutic programs across Moderna’s Research and Early Development portfolio.
Principal Ai/Ml Researcher WhoopPrincipal Ai/Ml ResearcherBoston, MA$270,000–$300,000 / yearDeep expertise in modern deep learning (transformers, state space models), multimodal training, self-supervised and representation learning, RL-based post-training (PPO/DPO/GRPO), and large-scale distributed training (data, model, and context parallelism). At WHOOP, we view total compensation as the combination of base salary, equity, and benefits, with equity serving as a key differentiator that aligns our employees with the long-term success of the company and allows every member of our corporate team to own part of WHOOP and share in the company's long-term growth and success.
Principal Consultant AppianPrincipal ConsultantBoston, MA$100,000–$225,000 / yearKnowledge of software testing practices (test-driven development, automated test suites within a continuous integration framework); integrations experience using APIs such as REST and SOAP, JDBC connections, and web services; familiarity with Amazon Web Services (AWS), Artificial Intelligence (AI), Analytics, Machine Learning, Google Cloud, Application Integration, Database, Developer Tools, Management & Governance, and Elastic Containers is preferred. This includes working within an agile environment to understand our client's business processes and technical needs, launch new relational data models in production, developing APIs to integrate with multiple systems, partnering with Appian Architects and Technical Delivery Managers, and leading/mentoring consultants through fast-paced software implementations.
Principal Scientist, mRNA-tLNP Analytical Development Kernal BiologicsPrincipal Scientist, mRNA-tLNP Analytical DevelopmentBoston, MassachusettsDevelop and qualify methods to characterize antibody–lipid bioconjugates and targeted LNPs, including conjugation efficiency, antibody-to-particle ratio and surface ligand density, free/unconjugated antibody, conjugate identity and integrity, and antigen-binding activity. Demonstrated expertise in developing analytical methods to test and characterize mRNA and LNP products, spanning both biophysical and biochemical techniques (particle size measurement, HPLC, LC-MS, CE, ELISA, qPCR, protein analysis, and in vitro potency assays).
Principal Engineer, CMC Development Pilot Operations ModernaTXPrincipal Engineer, CMC Development Pilot OperationsNorwood, MassachusettsThe Principal Engineer will partner closely with CMC Dev Quality, analytical testing laboratories, Process Development, Engineering, Safety, Digital, and the GMP manufacturing facility to ensure seamless material delivery, technical readiness, operational excellence, and robust transfer of product and process knowledge across the manufacturing network. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Principal Specialist, Quality Assurance Cardinal HealthPrincipal Specialist, Quality AssuranceMansfield, MassachusettsCross-functional Collaboration: Leads complex cross-functional projects to identify root causes of significant quality issues, educates stakeholders on quality requirements, and develops sustainable solutions to minimize future risks. The Principal Specialist, Quality Assurance, is a highly experienced individual contributor who applies advanced knowledge of quality assurance concepts and technical capabilities to drive uncompromised laboratory integrity and minimize risks.
Principal Program Manager – Embedded Aerospace Systems - 3643776 HRU-TechPrincipal Program Manager – Embedded Aerospace Systems - 3643776Hudson, New HampshireIn this role you will lead highly diverse cross functional teams composed of contracts, program planning, finance, operations, and engineering, to develop next-generation high-performance embedded processing solutions. You will support programs across our Compute Line of Business, where we design, develop, and produce embedded computers, networking appliances, storage solutions, and integration processing subsystems.
NewPrincipal FPGA Engineer Ayo SemiconductorPrincipal FPGA EngineerBoston, MassachusettsOur photonic processors will provide orders of magnitude improvement in speed and power efficiency in comparison to conventional digital compute platforms by taking advantage of the natural parallelism, speed and energy efficiency of light. Support the hardware team by performing FPGA trade studies and assessing the viability of proposed pin mappings on developmental circuit card assemblies.
Principal Embedded Software Engineer Lexington Medical, Inc.Principal Embedded Software EngineerBedford, MA$180,000–$220,000 / yearThe embedded software operates under tight real-time, safety-critical constraints, directly driving electromechanical subsystems where milliseconds and failure modes matter, and you will be in the lab working through hardware-software integration issues alongside electrical and mechanical engineers, not just reviewing designs from a distance. This is a hands-on role: you will be building the embedded software for our surgical stapling platform yourself, writing code, integrating drivers, and debugging at the hardware level, while also owning the technical architecture and setting the long-term direction for embedded systems across the platform.
Process Development Principal Scientist AmgenProcess Development Principal ScientistMassachusettsIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this vital role as an Attribute Sciences team lead and group lead you will work to provide strategic analytical leadership to teams developing commercial manufacturing processes for synthetic and hybrid molecules and collaborate closely with Drug Substance, Drug Product and Product Quality colleague.
BAS Principal - Valuation, Financial Forensics, Litigation (VFL) LitmanGerson AssociatesBAS Principal - Valuation, Financial Forensics, Litigation (VFL)Woburn, MA$140,000–$230,000 / yearFull timespecializing in a given subset Education and Experience:Bachelor's degree in Accountancy, Marketing, Finance, or a related fieldMaster's degree in Accountancy, Marketing, Finance or a plan to pursue preferredOne or more of the following credentials: certified public accountant (CPA), certified valuation analyst (CVA), accredited in business valuation (ABV), chartered financial analyst (CFA), certified business appraiser (CBA), accredited senior appraiser (ASA), certified divorce financial analyst (CDFA) CPA, CVA, ABV, CBA, or ASA certification is required 10+ years' of recent experience in a related field, with a proven ability to lead and develop client relationships. Acts as the firm's preeminent resource in specific technical areasProvides advice and council to clients, partners, and staffManages client expectations, develop solutions, and champions the implementation of client needs and ideasConsistently meets client deadlines timely and adheres to delivering specific client scopesIdentifies and recommends additional services that would be beneficial to clientsProvides exceptional customer service, ensuring client understands services, processes, etc.
Principal Design Quality Engineer I Nova BiomedicalPrincipal Design Quality Engineer IWaltham, MA$120,000–$160,000 / yearNova Biomedical is proud to be a global leader in osmolality testing and biotechnology and in vitro diagnostic (IVD) instrumentation, dedicated to advancing patient care and scientific discovery with a legacy that continues to shape the future of life sciences. With headquarters in Norwood and Waltham, Massachusetts, and a global team of nearly 2,000 employees, we’re building a collaborative, empowered culture grounded in shared values: Customer Centricity, Ingenuity, Ownership & Accountability, Collaboration, and Integrity .
Principal Network Engineer Sun Life FinancialPrincipal Network EngineerWellesley Hills, MA$70,300–$105,500 / yearAdvanced proficiency in Infrastructure as Code (IaC) using Terraform or AWS CloudFormation, paired with experience utilizing Generative AI developer tools (e.g., Amazon Q, Amazon Bedrock, or AI coding assistants) to accelerate code generation, automate network compliance validation, and scale CI/CD network deployment pipelines. The ideal candidate will have strong experience designing, implementing, and supporting enterprise network infrastructure, with expertise in Cisco routing and switching technologies, WatchGuard firewalls, AWS networking services, Infrastructure as Code, and utilizing Generative Developer tools.
Principal Mechanical Design Engineer RISE RoboticsPrincipal Mechanical Design EngineerSomerville, MAFounded in 2011 by graduates of MIT and RISD (Rhode Island School of Design), and backed by Engine Ventures, Techstars, Fortistar and Gates Corporation, RISE Robotics is leading the way to Zero Emission heavy machinery by providing the world’s most efficient and productive alternative to hydraulics. Proven technical aptitude and experience with electro-mechanical design and related manufacturing processes that might include: complex mechanical assemblies; rotating machinery; tolerance studies; design for assembly / manufacturing; EE and ME component and material selection; FMEA; design for life.
Principal Analyst, Enterprise Architecture Forrester Research, Inc.Principal Analyst, Enterprise ArchitectureCambridge, MA$141,000–$229,000 / yearA Principal Analyst is expected to: Lead the Enterprise Solutions Architecture practice area, working across Forrester research teams, including the Technology Strategy and Executive Partner teams as well as Sales and Product to develop a complete research portfolio that drives customer delight and revenue. Job Requirements: At least 10 years of experience in a mix of roles as a director-level and above practitioner, enterprise architect, principal sales engineer, principal solutions architect, managing consultant, Director/Manager of Sales Engineering, or research analyst in an industry vertical or technology services.
Principal Analyst - Technology Resilience Forrester Research, Inc.Principal Analyst - Technology ResilienceCambridge, MA$141,000–$229,000 / yearThe Principal Analyst delivers research that encompasses: 1) modern technology resilience practices, skills, and culture; 2) drive research on key platforms, vendors and trends in data resilience, object storage, and recovery related markets; 3) brings the right mix of both strategic and technical delivery experiences; and 4) fosters a culture of collaboration across our research, sales, product, and customer success teams. Deep understanding of the following concepts and industry best practices: site reliability engineering (SRE), National Incident Management System (NIMS), the National Response Framework (NRF), availability zones, ISO 22301, NIST SP 800-34, blameless retrospectives, CAST, fault injection, proactive and continuous testing, business impact analysis, immutability, and tabletop exercises.
Cyber Engineer Sr. Principal (On-site) HEPCO, Inc.Cyber Engineer Sr. Principal (On-site)Nashua, NH$80–$85 / hourModernize data center networks through spine-leaf architectures, intent-based networking, and high-availability design. This individual must be able to explain complex architectural strategies, demonstrate their business value, and effectively present and defend proposed solutions to technical stakeholders and executive leadership.