It builds on the Kostas Research Institute (KRI), CHEST (Center for Hardware and Embedded Systems Security and Trust), SENTRY (Soft Target Engineering to Neutralize the Threat Reality), DIBI (Defense Industrial Base Institute), and the Center for Advanced Materials for Resiliency (CAMR), connecting cryptography, AI, physical infrastructure resilience, cyber-AI security, and advanced manufacturing to safeguard the systems the nation depends on against natural disasters and both conventional and emerging (including quantum-era) threats. Anchored in Boston, the theme builds on cross-college collaboration among COE (College of Engineering), Khoury College of Computer Sciences, Mills (Mills College at Northeastern), CSSH (College of Social Sciences and Humanities), CAMD (College of Arts, Media and Design), COS (College of Science), and Law (School of Law), together with Northeastern's interdisciplinary ecosystem.