NewActuary – Financial Projection Modeling (Modeling Center of Excellence) MassMutualActuary – Financial Projection Modeling (Modeling Center of Excellence)Boston, MAAs the Actuary for Financial Projection Modeling, you’ll join the Modeling Center of Excellence (COE)—the team powering enterprise‑wide insights across FP&A, ALM, ERM, Treasury, and Capital Management. The team operates as a high‑impact Modeling Center of Excellence, bringing together advanced modeling expertise, strong business partnership, and technical innovation.
Model-Based Systems Engineer (MBSE) GCR Professional ServicesModel-Based Systems Engineer (MBSE)Woburn, Massachusetts$75–$90 / hourContractorRole can be Hybrid, TBD The Systems Engineer should have experience architecting systems, working across the Systems Engineering Lifecycle, and in Digital Engineering/Model-Based Systems Engineering (MBSE) achieving architectural integrity and traceability through requirements analysis, system and software development and production system deployment. The ideal candidate will be well-versed in Systems Engineering techniques, Modeling and Simulation, and Digital Engineering/MBSE and be excited about opportunities to mentor more junior staff and help foster growth of subject matter expertise across the organization.
NewLooker Data Modeling Engineer RESOURCESOFT, INC.Looker Data Modeling EngineerLexington, MAWe engage them in technology centric client projects that provide opportunities for them to evolve, innovate and deliver world class products and services. We partner with leading organizations to provide technology solutions within the financial, insurance, education, government, publishing, healthcare and pharmaceutical domains.
Simulation Modeling Engineer: 26-01627 Akraya Inc.Simulation Modeling Engineer: 26-01627Boston, MA$100–$107.38 / hourMost recently, we were recognized Stevie Employer of the Year 2025, SIA Best Staffing Firm to work for 2025, Inc 5000 Best Workspaces in US (2025 & 2024) and Glassdoor's Best Places to Work (2023 & 2022)! 1+ year cumulative experience with at least one of: game engines (Unreal, Unity), physics engines (Drake, MuJoCo, Bullet, PhysX), or robotics simulation platforms (Gazebo, Isaac Sim).
NewManager, AI-Ready Data Modeling 3316 Takeda Development Center AmericasManager, AI-Ready Data ModelingBoston, MassachusettsThe actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. As a Manager, AI-Ready Data Modeling, you will contribute to the development of high-quality, reusable, and AI-ready data models that support data-driven decision-making across R&D.
NewAssociate Director - Data Modeling 3316 Takeda Development Center AmericasAssociate Director - Data ModelingCambridge, Massachusettsdevelop knowledge graph products with functionality related to user-interfaces, views, search, LLM-augmented RAG (Retrieval Augmented Generative) conversational interfaces and other gen-AI components etc. to enable the dissemination of the knowledge & insights across R&D. As an Associate Director - Data Modeling, you will provide Data Modelling subject-matter-expertise to ensure high-quality analysis-ready data assets are created and utilized in a systematic manner for insight generation within R&D.
NewSenior Staff Engineer, Modeling and Data Applications 3316 Takeda Development Center AmericasSenior Staff Engineer, Modeling and Data ApplicationsLexington, MassachusettsThe actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. D. degree or a M.S. degree in biochemical engineering/biotechnology, data sciences, predictive modeling or closely related fields with 3+ years (PhD.) or 10+ years (M.S.) of experience in modeling and bioprocess development.
Senior Director, QSP/ PBPK Modeling Kiniksa Pharmaceuticals CorpSenior Director, QSP/ PBPK ModelingLexington, MA$281,000–$299,000 / yearStrong understanding of drug development, clinical trial design, and regulatory expectations related to pharmacology and pharmacometrics, experience contributing regulatory interactions related to modeling and simulation and proven experience applying modeling approaches to clinical decision making, particularly for early‑stage development programs. The successful candidate will serve as a scientific and strategic leader, partnering cross‑functionally with Research, Translational Medicine, Clinical Pharmacology, Clinical Development, and Regulatory teams to ensure model‑informed decision making across the portfolio.
Head Of Bermuda Model Development And Onboarding KKR & Co. Inc.Head Of Bermuda Model Development And OnboardingBoston, MA$170,000–$180,000 / yearKKR aims to generate attractive investment returns by following a patient and disciplined investment approach, employing world-class people, and supporting growth in its portfolio companies and communities. Lead the development, enhancement, and maintenance of actuarial models used for Bermuda EBS valuation, working in close partnership with the Bermuda Actuarial team.
Senior Machine Learning Scientist I, Model-Driven Optimization Generate Biomedicines IncSenior Machine Learning Scientist I, Model-Driven OptimizationSomerville, MA$192,000–$265,000 / yearThe ideal candidate combines depth in probabilistic machine learning, Bayesian optimization, active learning, or related approaches with the practical judgment and engineering discipline to turn technical ideas into reliable systems that drive impact. You will join a collaborative, ambitious team working to build a platform for therapeutic protein design that learns continuously from experimental data and turns that learning into new and better therapeutics with real impact.
NewSenior Staff Engineer, Modeling and Data Applications Takeda Pharmaceutical Co LtdSenior Staff Engineer, Modeling and Data ApplicationsLexington, MA$137,000–$215,270 / yearThe actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. D. degree or a M.S. degree in biochemical engineering/biotechnology, data sciences, predictive modeling or closely related fields with 3+ years (PhD.) or 10+ years (M.S.) of experience in modeling and bioprocess development.
Manager, AI-Ready Data Modeling Takeda Pharmaceutical Co LtdManager, AI-Ready Data ModelingBoston, MA$116,000–$182,270 / yearThe actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. About the role: As a Manager, AI-Ready Data Modeling, you will contribute to the development of high-quality, reusable, and AI-ready data models that support data-driven decision-making across R&D.
Associate Director - Data Modeling Takeda Pharmaceutical Co LtdAssociate Director - Data ModelingCambridge, MA$154,400–$242,550 / yearAbout the role: As an Associate Director - Data Modeling, you will provide Data Modelling subject-matter-expertise to ensure high-quality analysis-ready data assets are created and utilized in a systematic manner for insight generation within R&D. develop knowledge graph products with functionality related to user-interfaces, views, search, LLM-augmented RAG (Retrieval Augmented Generative) conversational interfaces and other gen-AI components etc. to enable the dissemination of the knowledge & insights across R&D.
Computational Modeling Consultant - CMC ZS Associates IncComputational Modeling Consultant - CMCBoston, MAYou will work closely with scientists, engineers, data teams, and senior CMC stakeholders to translate complex technical questions into scalable computational solutions that can be integrated into real-world scientific and manufacturing workflows. In this role, you will combine deep scientific and engineering expertise with first-principles and data-driven modeling to improve process understanding, accelerate development, support scale-up and technology transfer, and enable more informed decision-making.
Tech Staff Neurocognitive Analysis, Modeling, and Simulation MIT Lincoln LaboratoryTech Staff Neurocognitive Analysis, Modeling, and SimulationLexington, MA$145,200–$170,000 / yearOur core technical competencies include system-level modeling and gap analysis, advanced sensing and signal processing, machine learning and artificial intelligence, computational modeling, hardware and software prototyping, model-based systems engineering, and human data collection in laboratory and field environments. Analysis involves features based on mechanistic neuro-biophysical and neuro-motor computational modeling, neuromorphic (software and hardware) simulations, neural interface (e.g., EEG) technology, and machine learning coupled to brain imaging and neural tracing representations.
Associate Director or Director, PBPK & Biopharmaceutics Modeling Kymera TherapeuticsAssociate Director or Director, PBPK & Biopharmaceutics ModelingWatertown, MA$160,000–$275,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Experience modeling oral molecules with challenging developability profiles, including poorly soluble and/or permeable compounds and beyond-rule-of-five modalities such as targeted protein degraders (preferred).
Director, AI/ML MIDD Oncology Clinical Pharmacology, Modeling and Simulation GSK plcDirector, AI/ML MIDD Oncology Clinical Pharmacology, Modeling and SimulationWaltham, MA$188,100–$313,500 / yearBasic Qualifications: We are looking for professionals with these required skills to achieve our goals: A PhD in Quantitative Clinical Pharmacology and Pharmacometrics (e.g., pharmacology, engineering or statistics) or relevant Life Sciences discipline, and experience in using modelling/simulation to solve practical problems in industry or academia. Drug Design, Drug Development, Drug Discovery Process, Drug Discovery Research, Medication Safety, Molecular Modeling, Pharmaceutical Regulatory Compliance, Pharmaceutical Sciences, Pharmacodynamics, Pharmacokinetics, Pharmacology, Pharmacometrics, Pharmacovigilance, Study Design, Target Validation.
Senior Machine Learning Scientist I/II, Model-Driven Optimization Generate BiomedicinesSenior Machine Learning Scientist I/II, Model-Driven OptimizationSomerville, MassachusettsThe ideal candidate combines depth in probabilistic machine learning, Bayesian optimization, active learning, or related approaches with the practical judgment and engineering discipline to turn technical ideas into reliable systems that drive impact. You will join a collaborative, ambitious team working to build a platform for therapeutic protein design that learns continuously from experimental data and turns that learning into new and better therapeutics with real impact.
NewStaff Software Engineer, AI Foundation Model Merlin LabsStaff Software Engineer, AI Foundation ModelBoston, MA$225,000–$390,000 / yearBackground in simulation infrastructure, synthetic data generation, or domain randomization for training perception and control models using end to end ecosystems like NVIDIA Cosmos etc., Experience with onboard inference optimization - model quantization, TensorRT, hardware-aware compilation, or deployment on embedded accelerators. The Merlin Pilot autonomy system powers a growing range of aircraft and mission profiles and has been proven through hundreds of autonomous flights from Merlin's global flight test facilities, including Kerikeri, New Zealand; Quonset Point, Rhode Island; and soon, Bedford, Massachusetts.
Sr Data Scientist Treasury Modeling Citizens Financial Group IncSr Data Scientist Treasury ModelingBoston, MA$124,000–$165,000 / yearThe position also provides guidance to functional leaders on model impacts and partners with Model Risk Management, Market Risk, and Internal Audit to support model governance and regulatory requirements. The Central Model Development team within the Asset Liability Management group is responsible for developing and maintaining models that support strategic decision-making.