Executive Director, Oncology Translational Medicine, Clinical Pharmacology Modeling and Simulation GSK plcExecutive Director, Oncology Translational Medicine, Clinical Pharmacology Modeling and SimulationWaltham, MAWe have an exciting opportunity at GSK for a highly motivated and experienced Executive Director to join our team supporting the Oncology Clinical Pharmacology Modelling and Simulation (CPMS) department within Oncology Translational Medicine. This role focuses on delivering CPMS excellence to research and development programs, helping to accelerate the development of innovative oncology therapies by ensuring they reach the right patients, at the right dose, and at the right time.
Senior Director, QSP/ PBPK Modeling Kiniksa Pharmaceuticals CorpSenior Director, QSP/ PBPK ModelingLexington, MA$281,000–$299,000 / yearStrong understanding of drug development, clinical trial design, and regulatory expectations related to pharmacology and pharmacometrics, experience contributing regulatory interactions related to modeling and simulation and proven experience applying modeling approaches to clinical decision making, particularly for early‑stage development programs. The successful candidate will serve as a scientific and strategic leader, partnering cross‑functionally with Research, Translational Medicine, Clinical Pharmacology, Clinical Development, and Regulatory teams to ensure model‑informed decision making across the portfolio.
Systems Modeling, Simulation & Analysis Engineer Judit IncSystems Modeling, Simulation & Analysis EngineerLexington, MAResponsibilities include but not limited to: Independently adding features and capabilities to the existing Matlab codebase, including the technical background to accurately model basic physics phenomenology in terms of RF propagation, electronic warfare, missile flyouts, sensors etc. Performing quality control on new features and the existing code base to include adding unit tests, and other capabilities to ensure that the results are accurate and that new features are interacting appropriately with the rest of the codebase.
Principal Modeling And Simulation Engineer Berkshire Grey Inc.Principal Modeling And Simulation EngineerBedford, MAIn the role of Principal Modeling and Simulation Engineer, you will lead the development of high-fidelity simulation platforms and digital twins that drive system design, validation, and deployment. This role blends advanced software engineering with modeling and simulation, enabling rapid development, testing, and optimization of complex robotic systems.
Systems Modeling, Simulation and Analysis Engineer Connexion Systems + EngineeringSystems Modeling, Simulation and Analysis EngineerWaltham, MA$70–$95 / hourSeeking a Systems Modeling, Simulation, and Analysis Engineer to support the continued development and enhancement of existing MATLAB-based modeling tools. The engineer will work closely with cross-functional teams to understand evolving requirements, implement new modeling capabilities, and support analytical efforts.
Senior Staff Engineer, Modeling and Data Applications 3316 Takeda Development Center AmericasSenior Staff Engineer, Modeling and Data ApplicationsLexington, MassachusettsThe actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. D. degree or a M.S. degree in biochemical engineering/biotechnology, data sciences, predictive modeling or closely related fields with 3+ years (PhD.) or 10+ years (M.S.) of experience in modeling and bioprocess development.
Tech Staff Neurocognitive Analysis, Modeling, and Simulation MIT Lincoln LaboratoryTech Staff Neurocognitive Analysis, Modeling, and SimulationLexington, MA$145,200–$170,000 / yearOur core technical competencies include system-level modeling and gap analysis, advanced sensing and signal processing, machine learning and artificial intelligence, computational modeling, hardware and software prototyping, model-based systems engineering, and human data collection in laboratory and field environments. Analysis involves features based on mechanistic neuro-biophysical and neuro-motor computational modeling, neuromorphic (software and hardware) simulations, neural interface (e.g., EEG) technology, and machine learning coupled to brain imaging and neural tracing representations.
Director, AI/ML MIDD Oncology Clinical Pharmacology, Modeling and Simulation GSK plcDirector, AI/ML MIDD Oncology Clinical Pharmacology, Modeling and SimulationWaltham, MA$188,100–$313,500 / yearBasic Qualifications: We are looking for professionals with these required skills to achieve our goals: A PhD in Quantitative Clinical Pharmacology and Pharmacometrics (e.g., pharmacology, engineering or statistics) or relevant Life Sciences discipline, and experience in using modelling/simulation to solve practical problems in industry or academia. Drug Design, Drug Development, Drug Discovery Process, Drug Discovery Research, Medication Safety, Molecular Modeling, Pharmaceutical Regulatory Compliance, Pharmaceutical Sciences, Pharmacodynamics, Pharmacokinetics, Pharmacology, Pharmacometrics, Pharmacovigilance, Study Design, Target Validation.
Group 04-47 | SRP Intern - Power System Modeling | Energy Systems | Summer 2026 (Lexington, MA, US) MIT Lincoln LaboratoryGroup 04-47 | SRP Intern - Power System Modeling | Energy Systems | Summer 2026 (Lexington, MA, US)Lexington, MAThis includes developing advanced architectures and system designs to improve the resilience of power grids, developing new control techniques for microgrids and distributed energy resources, and developing hardware and real-time simulation testbeds. The candidate will develop power distribution system models to understand how generation sources (both traditional diesel and natural gas-fired as well as renewables), electric vehicles, energy storage, and distribution system configurations can be best design to support reliable power delivery.
Modeling & Simulation Engineer Connexion Systems + EngineeringModeling & Simulation EngineerBedford, MAThis role will involve developing, maintaining, verifying, validating, and executing large-scale modeling and simulation tools used to evaluate aircraft encounters, collision avoidance systems, sensors, tracking systems, pilot response, and aircraft maneuvering. The team performs fast-time, Monte Carlo simulations at large scale , using simulation and statistical analysis to identify failure conditions, evaluate system performance, and provide findings to government sponsors and external collaborators.
Summer Internship in AI-Driven Materials & Electrical Modeling Engineering I1060H E Ink CorporationSummer Internship in AI-Driven Materials & Electrical Modeling Engineering I1060HBillerica, MA$25–$35 / hourOur culture is built on value commitments to innovation, quality, results, integrity, community, people, and collaboration that fosters a strong employee engagement, teamwork, safety and wellness. About the Position: In this role, you will contribute to the development of next-generation materials for microcapsule coating systems by integrating AI-driven research approaches with physical modeling and experimental validation.
Senior Director, Qsp/ Pbpk Modeling Kiniksa PharmaceuticalSenior Director, Qsp/ Pbpk ModelingLexington, MAStrong understanding of drug development, clinical trial design, and regulatory expectations related to pharmacology and pharmacometrics, experience contributing regulatory interactions related to modeling and simulation and proven experience applying modeling approaches to clinical decision making, particularly for early‑stage development programs. The successful candidate will serve as a scientific and strategic leader, partnering cross‑functionally with Research, Translational Medicine, Clinical Pharmacology, Clinical Development, and Regulatory teams to ensure model‑informed decision making across the portfolio.
Mission Modeling and Simulation, Lead Mitre CorpMission Modeling and Simulation, LeadBedford, MA$155,200–$194,000 / yearMITRE Technology and Engineering (MTE) System Engineering Technical Division is seeking an experienced, highly motivated Lead Mission Modeling and Simulation Engineer to support defense mission engineering, system of systems analysis, and decision-support activities for complex operational missions. Experience evaluating kinetic and non-kinetic mission operations, including one or more of the following domains: air, maritime, land, space, cyber, electromagnetic spectrum operations, communications, command and control, fires, logistics, ISR, autonomy, or integrated air and missile defense.
Principal Modeling and Simulation Engineer Berkshire Grey IncPrincipal Modeling and Simulation EngineerBedford, MAProficient in: Simulation software development and system modeling frameworks Emulate3D or Sim3D (Rockwell Automation) (required) Nividia Omniverse System design and software architecture Asynchronous / concurrent programming Git, Jira, and modern development workflows Linux / Ubuntu environments Code reviews, testing methodologies, and CI/CD practices Software design patterns (modular, scalable, fault-tolerant systems). Demonstrated ability to: Architect and deliver large-scale simulation and software systems Operate autonomously and drive projects from concept to production Define and communicate technical strategy, tradeoffs, and priorities Navigate and contribute to large, complex codebases Apply an MVP mindset while scaling solutions from prototype to production.
Sr. Advanced Manufacturing Engineer - Modeling & Drafting, Advanced Manufacturing Engineering (AME) Amazon.com IncSr. Advanced Manufacturing Engineer - Modeling & Drafting, Advanced Manufacturing Engineering (AME)MAYou will create and interpret complex 3D models and 2D production drawings, work cross-functionally to develop suppliers, manage product lifecycle changes, oversee manufacturing readiness assessments, and drive technical root cause for supplier defects. You"ll collaborate daily with cross-functional stakeholders across Hardware Engineering, Supply Chain, Quality, and Program Management, and you"ll see the direct impact of your modeling and drafting skills as designs move from prototype to high-volume global production.
Modeling, Simulation and Analysis Systems Engineer BAE Systems PlcModeling, Simulation and Analysis Systems EngineerNashua, NH$149,603–$254,317 / yearAbout BAE Systems Electronic Systems BAE Systems, Inc. is the U.S. subsidiary of BAE Systems plc, an international defense, aerospace and security company which delivers a full range of products and services for air, land and naval forces, as well as advanced electronics, security, information technology solutions and customer support services. We are seeking systems engineers experienced in modeling and simulation environments to develop, build, and work on the world's most advanced electromagnetic spectrum operations systems - detecting, identifying, locating, and countering threats for joint forces and international aircrew.
Systems Modeling, Simulation And Analysis Engineer AthariSystems Modeling, Simulation And Analysis EngineerLexington, MA$75–$100 / hourPerforming modeling runs needed for analysis and building tools that allow for efficient. Responsibilities include but not limited to: Independently adding features and capabilities to the existing Matlab codebase, including.
Principal EW Modeling & Simulation Engineer BAE Systems PlcPrincipal EW Modeling & Simulation EngineerNashua, NH$118,095–$200,762 / yearAbout BAE Systems Electronic Systems BAE Systems, Inc. is the U.S. subsidiary of BAE Systems plc, an international defense, aerospace and security company which delivers a full range of products and services for air, land and naval forces, as well as advanced electronics, security, information technology solutions and customer support services. We welcome all those who have big ideas, crave innovation, and want to develop, build and work on the world's most advanced electromagnetic spectrum operations systems - detecting, locating and countering threats for joint and international aircrew.
Modeling and Simulation Engineer Abacus TechnologyModeling and Simulation EngineerHanscom AFB, Massachusetts$135,600–$152,000 / yearKnowledge and experience must include reviewing modeling work for compliance with regulations and best practices; developing and maintaining modeling best practices; analyzing complex problems; developing relevant models and constraints to run complex dynamic structural, thermal or other analyses; and reviewing and supporting work to develop appropriate models to solve complex weapon system issues including networking and communications. Apply analysis tools, object models, and analytical techniques to support mission-level analyses, to include the performance of military communication networks, susceptibility to threats (kinetic, EMP, Cyber, etc.), concept alternatives characterization, development planning, and the analysis of new systems, technologies, effectiveness, and lethality.
NewSystems Engineer - RF Integration & Performance Modeling BAE Systems PlcSystems Engineer - RF Integration & Performance ModelingNashua, NH$97,008–$164,914 / yearAbout BAE Systems Electronic Systems BAE Systems, Inc. is the U.S. subsidiary of BAE Systems plc, an international defense, aerospace and security company which delivers a full range of products and services for air, land and naval forces, as well as advanced electronics, security, information technology solutions and customer support services. Our ACES team is seeking a highly motivated systems engineer to support the development of new Electronic Attack (EA) capabilities designed to improve air vehicle survivability by detecting, denying, deceiving, degrading, and disrupting adversary Integrated Air Defenses.