Model-Based Systems Engineer (MBSE) GCR Professional ServicesModel-Based Systems Engineer (MBSE)Woburn, Massachusetts$75–$90 / hourContractorRole can be Hybrid, TBD The Systems Engineer should have experience architecting systems, working across the Systems Engineering Lifecycle, and in Digital Engineering/Model-Based Systems Engineering (MBSE) achieving architectural integrity and traceability through requirements analysis, system and software development and production system deployment. The ideal candidate will be well-versed in Systems Engineering techniques, Modeling and Simulation, and Digital Engineering/MBSE and be excited about opportunities to mentor more junior staff and help foster growth of subject matter expertise across the organization.
Simulation Modeling Engineer: 26-01627 Akraya Inc.Simulation Modeling Engineer: 26-01627Boston, MA$100–$107.38 / hourMost recently, we were recognized Stevie Employer of the Year 2025, SIA Best Staffing Firm to work for 2025, Inc 5000 Best Workspaces in US (2025 & 2024) and Glassdoor's Best Places to Work (2023 & 2022)! 1+ year cumulative experience with at least one of: game engines (Unreal, Unity), physics engines (Drake, MuJoCo, Bullet, PhysX), or robotics simulation platforms (Gazebo, Isaac Sim).
VP Mortgage Pipeline Valuation and Risk Modeling Citizens Financial Group IncVP Mortgage Pipeline Valuation and Risk ModelingMA$161,000–$214,000 / yearThis role will lead the QRM function from both a technical and managerial perspective, owning the development and enhancement of advanced modeling frameworks including interest rate shock modeling, option-adjusted analytics, pipeline valuation, fallout modeling, and best execution. This role will partner closely with ALM, MSR, Finance, Risk, Technology, and Model Validation teams to ingest data, support cross-functional initiatives, and ensure QRM outputs are aligned with enterprise risk management, valuation, and capital markets objectives.
Director/Senior Director, ADMET & PK/PD Modeling Eli Lilly and CoDirector/Senior Director, ADMET & PK/PD ModelingBoston, MA$177,000–$308,000 / yearOur current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Through its interconnected pillars-Lilly Ventures, Lilly Gateway Labs, Lilly ExploR&D, and Lilly TuneLab-Catalyze360 strategically removes barriers that traditionally block bold science from becoming life-changing medicines, providing biotechs with flexible combinations of capital, physical lab space, R&D capabilities, AI/ML tools, and decades of enterprise learning.
Sr Data Scientist Treasury Modeling Citizens Financial Group IncSr Data Scientist Treasury ModelingBoston, MA$124,000–$165,000 / yearThe position also provides guidance to functional leaders on model impacts and partners with Model Risk Management, Market Risk, and Internal Audit to support model governance and regulatory requirements. The Central Model Development team within the Asset Liability Management group is responsible for developing and maintaining models that support strategic decision-making.
Senior Software Engineer - Data Modeling Arrowstreet Capital LPSenior Software Engineer - Data ModelingBoston, MA$135,000–$325,000 / yearThe determination of a successful candidate's base salary placement within the listed range will vary based on the candidate's relevant experience and qualifications (which may also include relevant certifications, credentials and other education), the job responsibilities and scope, the commensurate resulting level of the position and other relevant factors. The Senior Software Engineer - Data Modeling will work within Research Systems as part of the Data Models, Forecast Platform team, and be focused on the implementation of our next generation platform as part of a modern research data platform.
Executive Director, Modeling & Simulations Vertex Pharmaceuticals IncExecutive Director, Modeling & SimulationsBoston, MA$268,000–$402,000 / yearThe incumbent is responsible for the implementation of modeling and simulation strategy at Vertex; including but not limited to traditional PK/PD, population PK, exposure-response, model-based meta-analysis, clinical trial design and simulation, mathematical disease models, mechanistic modeling and analyses of multidimensional data This role will have final approval on providing direction and guidance for M&S plans across programs. Typically requires the following: PhD with 20 years or Master's Degree with 25 years' experience in the application of pharmacometric and other modeling methodologies in the context of drug research & development in industry, academia or regulatory agencies.
Deals Services - Manager, Strategic Finance and FP&A, Advanced Decision Modeling RSM US LLPDeals Services - Manager, Strategic Finance and FP&A, Advanced Decision ModelingBoston, MA$112,100–$225,500 / yearThe salary range (or starting rate for interns and associates) for this role represents numerous factors considered in the hiring decisions including, but not limited to, education, skills, work experience, certifications, location, etc. Develops and reviews complex, fully integrated financial models, including operating, cash flow, valuation, and transaction models, to support strategic decision-making.
Quantum Scientist - AMO Theory and Device Modeling QuEra Computing IncQuantum Scientist - AMO Theory and Device ModelingBoston, MA$130,400–$211,900 / yearQuEra Computing is seeking a talented and innovative theorist with a strong background in theoretical atomic, molecular, and optical (AMO) physics and quantum information science to support the modeling and architecture development of our digital neutral-atom quantum computers. Experience modeling AMO experiments, including realistic multi-level atomic structure calculations, light-matter interactions, and Rydberg physics.
GTM Planning Performance & Modeling Senior Associate Grant Thornton LLPGTM Planning Performance & Modeling Senior AssociateBoston, MA$96,000–$144,000 / yearIn the U.S., Grant Thornton delivers professional services through two specialized entities: Grant Thornton LLP, a licensed, certified public accounting (CPA) firm that provides audit and assurance services ― and Grant Thornton Advisors LLC (not a licensed CPA firm), which exclusively provides non-attest offerings, including tax and advisory services. With $2.7 billion in revenues and more than 50 offices spanning the U.S., Ireland and other territories, the platform delivers a singular client experience that includes enhanced solutions and capabilities, backed by powerful technologies and a roster of 12,000 quality-driven professionals enjoying exceptional career-growth opportunities and a distinctive cross-border culture.
Senior EMS Modeling Engineer TRC Companies, Inc.Senior EMS Modeling EngineerBoston, Massachusetts$103,084.80–$165,000 / yearFull timeOther Compensation: Employee may be eligible for participation in the Company’s annual Discretionary Bonus Program which is contingent on Company, Business Segment, and Individual performance against Key Performance Indicators which vary by year and employee. We recognize that the expertise of our staff is our strongest asset, so we generously reward employees for successful performance and invest in their careers through training and the development of new skills and certifications.
EMS Modeling Engineer TRC Companies, Inc.EMS Modeling EngineerBoston, Massachusetts$89,128–$120,000 / yearFull timeOther Compensation: Employee may be eligible for participation in the Company’s annual Discretionary Bonus Program which is contingent on Company, Business Segment, and Individual performance against Key Performance Indicators which vary by year and employee. We recognize that the expertise of our staff is our strongest asset, so we generously reward employees for successful performance and invest in their careers through training and the development of new skills and certifications.
Tech Staff Neurocognitive Analysis, Modeling, and Simulation MIT Lincoln LaboratoryTech Staff Neurocognitive Analysis, Modeling, and SimulationLexington, MA$145,200–$170,000 / yearOur core technical competencies include system-level modeling and gap analysis, advanced sensing and signal processing, machine learning and artificial intelligence, computational modeling, hardware and software prototyping, model-based systems engineering, and human data collection in laboratory and field environments. Analysis involves features based on mechanistic neuro-biophysical and neuro-motor computational modeling, neuromorphic (software and hardware) simulations, neural interface (e.g., EEG) technology, and machine learning coupled to brain imaging and neural tracing representations.
Principal Scientist II/Senior Principal Scientist, Modeling & Simulation (Dual Level Posting) Novartis AGPrincipal Scientist II/Senior Principal Scientist, Modeling & Simulation (Dual Level Posting)Cambridge, MA$126,000–$234,000 / yearEngage in strategic initiatives within M&S, such as creating platform-level translational modeling strategies to impact across projects and developing modeling workflows (e.g., agentic AI).• Proactively seek opportunities to increase the understanding and adoption of translational modeling among internal partners and expand the impact and visibility of modeling through external collaborations. As part of a truly translational modeling team, you will also work closely with clinical pharmacology and pharmacometrics groups to support clinical programs, applying quantitative systems pharmacology (QSP) and mechanistic PBPK/PD approaches to inform key decisions from early dose optimization through life-cycle management.
Deals Services - Supervisor, Strategic Finance and FP&A, Advanced Decision Modeling RSM US LLPDeals Services - Supervisor, Strategic Finance and FP&A, Advanced Decision ModelingBoston, MA$101,000–$203,000 / yearIf you are a recent U.S. college / university graduate possessing 1-2 years of progressive and relevant work experience in a same or similar role to the one for which you are applying, excluding internships, you may be eligible for hire as an experienced associate. The salary range (or starting rate for interns and associates) for this role represents numerous factors considered in the hiring decisions including, but not limited to, education, skills, work experience, certifications, location, etc.
Risk Modeling Services P&C - Director PricewaterhouseCoopers LLPRisk Modeling Services P&C - DirectorMA$134,000–$348,500 / yearProven leadership in large-scale financial engagements • Managing multi-disciplinary teams • Possessing thought leader-level cloud platform knowledge • Exhibiting mastery of programming languages • Understanding advanced analytical applications in finance • Developing large-scale cloud and data strategies • Overseeing complex project success and client satisfaction • Driving revenue growth through new business opportunities • Building and maintaining senior-level client relationships. PwC does not intend to hire experienced or entry level job seekers who will need, now or in the future, PwC sponsorship through the H-1B lottery, except as set forth within the following policy: https://pwc.to/H-1B-Lottery-Policy .
Deals Services - Manager, Strategic Finance and FP&A, Advanced Decision Modeling RSMDeals Services - Manager, Strategic Finance and FP&A, Advanced Decision ModelingBoston, MassachusettsThe salary range (or starting rate for interns and associates) for this role represents numerous factors considered in the hiring decisions including, but not limited to, education, skills, work experience, certifications, location, etc. Develops and reviews complex, fully integrated financial models, including operating, cash flow, valuation, and transaction models, to support strategic decision-making.
Modeling & Simulations Associate Director Vertex PharmaceuticalsModeling & Simulations Associate DirectorBoston, MassachusettsThe Modeling & Simulations Associate Director will be responsible for developing and executing M&S strategies and activities in cross functional drug development project teams in close collaboration with colleagues in Clinical Pharmacology, Biostatistics, Research and other colleagues within the R&D. Typically requires the following: PhD and 6 years experience or Master's Degree and 10 years experience in the application of Pharmacometric and other Modeling methodologies in the context of drug research & development in industry, academia or regulatory agencies.
Quantum Scientist - AMO Theory and Device Modeling QuEra ComputingQuantum Scientist - AMO Theory and Device ModelingBoston, MassachusettsQuEra Computing is seeking a talented and innovative theorist with a strong background in theoretical atomic, molecular, and optical (AMO) physics and quantum information science to support the modeling and architecture development of our digital neutral-atom quantum computers. Experience modeling AMO experiments, including realistic multi-level atomic structure calculations, light-matter interactions, and Rydberg physics.
Deals Services - Supervisor, Strategic Finance and FP&A, Advanced Decision Modeling RSMDeals Services - Supervisor, Strategic Finance and FP&A, Advanced Decision ModelingBoston, MassachusettsIf you are a recent U.S. college / university graduate possessing 1-2 years of progressive and relevant work experience in a same or similar role to the one for which you are applying, excluding internships, you may be eligible for hire as an experienced associate. The salary range (or starting rate for interns and associates) for this role represents numerous factors considered in the hiring decisions including, but not limited to, education, skills, work experience, certifications, location, etc.
Tech Staff Neurocognitive Analysis, Modeling, and Simulation Lincoln LaboratoryTech Staff Neurocognitive Analysis, Modeling, and SimulationLexington, MA$145,200–$170,000 / yearOur core technical competencies include system-level modeling and gap analysis, advanced sensing and signal processing, machine learning and artificial intelligence, computational modeling, hardware and software prototyping, model-based systems engineering, and human data collection in laboratory and field environments. Analysis involves features based on mechanistic neuro-biophysical and neuro-motor computational modeling, neuromorphic (software and hardware) simulations, neural interface (e.g., EEG) technology, and machine learning coupled to brain imaging and neural tracing representations.
Senior Analyst - Strategic Transaction Analysis & Modeling Goodwin ProcterSenior Analyst - Strategic Transaction Analysis & ModelingBoston, MassachusettsThe Strategic Transaction Analysis & Modeling team (“Team”) specializes in the analysis and modeling of corporate transactions, supporting attorneys and clients in evaluating strategic business decisions and driving deal execution. As part of the Global Operations Team – all business professionals at the firm – you’ll collaborate with colleagues from varied backgrounds and experiences, fostering an environment where cross-functional learning, networking, and collaboration are at the core of what we do.
FP&A Manager - Revenue Forecasting & Predictive Modeling FlywireFP&A Manager - Revenue Forecasting & Predictive ModelingBoston, MA$105,000–$135,000 / yearOwn and manage the end-to-end revenue forecasting process, including development of the annual budget, quarterly forecasts (QBRs), and long-range strategic plans (LRP) based on key business drivers (e.g., customer churn, net retention rate, volume metrics). Design and implement robust Transactional & SaaS/Subscription revenue models (e.g., based on cohorts, top clients, bookings/billings/ARR/MRR drivers) to accurately project future performance under various scenarios.
Lead Data Engineer - Data Transformation (Modeling and Architecture) Capital One Financial CorpLead Data Engineer - Data Transformation (Modeling and Architecture)Cambridge, MA$197,300–$225,100 / yearShare your passion for staying on top of tech trends, experimenting with and learning new technologies, participating in internal & external technology communities, and mentoring other members of the engineering community. Candidates hired to work in other locations will be subject to the pay range associated with that location, and the actual annualized salary amount offered to any candidate at the time of hire will be reflected solely in the candidate's offer letter.
Senior Deep Learning Hardware Modeling Architect - LPU NVIDIA CorpSenior Deep Learning Hardware Modeling Architect - LPUMAIf you are passionate about LLM inference hardware, want to contribute at the deepest levels to the state of the art, and have a proven record of C++ hardware modeling experience, this role may be perfect for you! The base salary range is 152,000 USD - 241,500 USD for Level 3, and 184,000 USD - 287,500 USD for Level 4. You will also be eligible for equity and benefits.
Modeling and Simulations Environment Systems Engineer BAE Systems PlcModeling and Simulations Environment Systems EngineerNashua, NHfor description visit the url https://jobs.baesystems.com/global/en/job/BAE1US122847BREXTERNAL/Modeling-and-Simulations-Environment-Systems-Engineer .
Business Data Delivery Lead - Data Architecture, Modeling & Enablement Citizens Financial Group IncBusiness Data Delivery Lead - Data Architecture, Modeling & EnablementMA$157,000–$209,000 / yearThis individual combines deep technical expertise in data architecture, modeling, and ETL with strong delivery leadership, acting as the primary liaison between business stakeholders, data engineering, and enterprise data teams within a regulated financial services environment. Lead the design, development, and delivery of data enablement solutions, including ETL/ELT pipelines from source ingestion through modeled, consumption-ready datasets.
Systems Modeling, Simulation and Analysis Engineer Connexion Systems + EngineeringSystems Modeling, Simulation and Analysis EngineerWaltham, MA$70–$95 / hourSeeking a Systems Modeling, Simulation, and Analysis Engineer to support the continued development and enhancement of existing MATLAB-based modeling tools. The engineer will work closely with cross-functional teams to understand evolving requirements, implement new modeling capabilities, and support analytical efforts.
Systems Modeling, Simulation & Analysis Engineer Judit IncSystems Modeling, Simulation & Analysis EngineerLexington, MAResponsibilities include but not limited to: Independently adding features and capabilities to the existing Matlab codebase, including the technical background to accurately model basic physics phenomenology in terms of RF propagation, electronic warfare, missile flyouts, sensors etc. Performing quality control on new features and the existing code base to include adding unit tests, and other capabilities to ensure that the results are accurate and that new features are interacting appropriately with the rest of the codebase.
Systems Modeling, Simulation and Analysis Engineer AthariSystems Modeling, Simulation and Analysis EngineerLexington, MAPerforming modeling runs needed for analysis and building tools that allow for efficient. Responsibilities include but not limited to: Independently adding features and capabilities to the existing Matlab codebase, including.
Director, Modeling & Simulation Novartis AGDirector, Modeling & SimulationCambridge, MA$176,400–$327,600 / yearEstablished credibility in the M&S or quantitative pharmacology community (e.g., publications, collaborations, or scientific leadership).Fluency in English (oral and written).This is a hybrid role that requires a balance of in-person and virtual working, with an average of 12 days a month on site in Cambridge, MA.The salary for this position is expected to range between:Director: $176,400 and $327,600 per year. D. in biology, bioengineering, pharmaceutical sciences, biophysics, or a related field.10+ years of relevant postdoctoral, academic, industry, or government experience with a track record as a leader and individual contributor in one or more of the following fields: Disease Modeling, Pathway Modeling, Quantitative Pharmacology, Systems Pharmacology, Mechanistic Modeling.
QSP Modeling Lead, Oncology R&D, Orion Corporation Orion CorpQSP Modeling Lead, Oncology R&D, Orion CorporationBoston, MA$130,000–$230,000 / yearThe role of QSP Modeling Lead will be responsible for generating and implementing mechanistic pharmacology models to support drug development at all stages, from preclinical research to clinical trials and beyond, aiding in dose optimization, biomarker identification, safety and efficacy assessment, and drug development decision-making, leveraging integrated non-clinical and clinical data. The successful candidate will serve as a scientific and strategic leader, partnering cross‑functionally with in Translational Pharmacology, DMPK, Pharmacometrics, Clinical Biomarkers, Bioinformaticians, Research, and Clinical Development to ensure model‑informed decision making across the portfolio.
Modeling & Simulation Engineer II/III Textron IncModeling & Simulation Engineer II/IIIWilmington, MA$92,600–$139,600 / yearBenefits may include health insurance and prescription plan coverage, dental insurance, family building benefits, vision insurance, mental health resources, flexible spending accounts, health savings accounts, retirement savings plans, life and disability insurance programs, and programs that provide employees time away from work. Recruiting Company: Textron Systems Primary Location: US-Massachusetts-Wilmington Job Function: Engineering Schedule: Full-time Job Level: Individual Contributor Job Type: Experienced Shift: First Shift Travel: Yes, 10 % of the Time Job Posting: 04/28/2026, 11:43:01 AM Job Number: 341522.
NewModeling & Simulation Engineer Connexion Systems + EngineeringModeling & Simulation EngineerLexington, MA$60–$95 / hourWe're seeking two Modeling & Simulation Engineers to develop, maintain, validate, and enhance simulation environments supporting the analysis and evaluation of advanced aerospace and autonomous systems. Strong written and verbal communication skills, with the ability to present technical results to both technical and non-technical audiences.
Executive Director, Oncology Translational Medicine, Clinical Pharmacology Modeling and Simulation GSK plcExecutive Director, Oncology Translational Medicine, Clinical Pharmacology Modeling and SimulationWaltham, MAWe have an exciting opportunity at GSK for a highly motivated and experienced Executive Director to join our team supporting the Oncology Clinical Pharmacology Modelling and Simulation (CPMS) department within Oncology Translational Medicine. This role focuses on delivering CPMS excellence to research and development programs, helping to accelerate the development of innovative oncology therapies by ensuring they reach the right patients, at the right dose, and at the right time.
Senior Model Risk Analyst Brown Brothers Harriman & CoSenior Model Risk AnalystBoston, MA$100,000–$150,000 / yearBachelor's degree and a minimum of 8 years of experience in computer science (or relevant field) Master's degree preferred; Demonstrated programming skills in languages such as Python, R, SQL for data modeling; Experience in data analysis techniques and metrics; knowledge of relational database technologies using SQL is a plus; Working knowledge with Python, R, SQL, or low/no-code/LLM tools for data modeling and/or large-scale data analysis projects; Strong writing and experience briefing technical findings. EMRM is a multi-disciplinary team within Operational Risk that uses applied concepts in econometrics, financial forecasting, balance sheet management, capital liquidity, and financial regulatory requirements management to evaluate firm-wide models, machine learning algorithms, and Gen-AI use cases.
Senior Machine Learning Scientist I, Model-Driven Optimization Generate BiomedicinesSenior Machine Learning Scientist I, Model-Driven OptimizationSomerville, MassachusettsThe ideal candidate combines depth in probabilistic machine learning, Bayesian optimization, active learning, or related approaches with the practical judgment and engineering discipline to turn technical ideas into reliable systems that drive impact. You will join a collaborative, ambitious team working to build a platform for therapeutic protein design that learns continuously from experimental data and turns that learning into new and better therapeutics with real impact.
Principal Modeling Engineer MACOM Technology Solutions Holdings IncPrincipal Modeling EngineerLowell, MAThe individual will be responsible for developing Process Design Kits (PDK) and device models to assist product design across the breadth of MACOMs product portfolio - GaAs, GaN, and Si based semiconductor ICs and modules. Device test support where needed and software development to automate electrical test for device characterization and model extraction.
Modeling and Simulation Engineer Abacus TechnologyModeling and Simulation EngineerHanscom AFB, Massachusetts$135,600–$152,000 / yearKnowledge and experience must include reviewing modeling work for compliance with regulations and best practices; developing and maintaining modeling best practices; analyzing complex problems; developing relevant models and constraints to run complex dynamic structural, thermal or other analyses; and reviewing and supporting work to develop appropriate models to solve complex weapon system issues including networking and communications. Apply analysis tools, object models, and analytical techniques to support mission-level analyses, to include the performance of military communication networks, susceptibility to threats (kinetic, EMP, Cyber, etc.), concept alternatives characterization, development planning, and the analysis of new systems, technologies, effectiveness, and lethality.
Summer Internship in AI-Driven Materials & Electrical Modeling Engineering I1060H E Ink CorporationSummer Internship in AI-Driven Materials & Electrical Modeling Engineering I1060HBillerica, MA$25–$35 / hourOur culture is built on value commitments to innovation, quality, results, integrity, community, people, and collaboration that fosters a strong employee engagement, teamwork, safety and wellness. About the Position: In this role, you will contribute to the development of next-generation materials for microcapsule coating systems by integrating AI-driven research approaches with physical modeling and experimental validation.
Senior Analyst Pricing and Risk Modeling - Hybrid Andover MA Enel SpASenior Analyst Pricing and Risk Modeling - Hybrid Andover MAMA$118,938–$178,407 / yearEnel Green Power, the Group's renewables arm, has a total capacity of approximately 68 GW and a generation mix that includes wind, solar, geothermal, and hydroelectric power, as well as energy storage facilities, installed in Europe, the Americas, Africa, Asia, and Oceania. Enel Grids, the Group's global business line dedicated to the management of the electricity distribution service worldwide, delivers electricity through a network of 1.9 million kilometers with more than 69 million end users connected to its distribution grids.
NewSenior Software Modeling Engineer ARM LtdSenior Software Modeling EngineerWaltham, MA$161,500–$218,500 / yearThese platforms enable partners to start software development earlier, accelerate validation, and perform advanced debugging and system analysis, including into low-level memory bus transactions. The modeling team in Arm's Central Engineering Software (CE-SW) division enables customers across domains such as IoT, Client, and Infrastructure to develop and validate software on Arm IP-based systems.
Senior Machine Learning Scientist I, Model-Driven Optimization Generate Biomedicines IncSenior Machine Learning Scientist I, Model-Driven OptimizationSomerville, MA$192,000–$265,000 / yearThe ideal candidate combines depth in probabilistic machine learning, Bayesian optimization, active learning, or related approaches with the practical judgment and engineering discipline to turn technical ideas into reliable systems that drive impact. You will join a collaborative, ambitious team working to build a platform for therapeutic protein design that learns continuously from experimental data and turns that learning into new and better therapeutics with real impact.
Principal Modeling and Simulation Engineer Berkshire Grey IncPrincipal Modeling and Simulation EngineerBedford, MAProficient in: Simulation software development and system modeling frameworks Emulate3D or Sim3D (Rockwell Automation) (required) Nividia Omniverse System design and software architecture Asynchronous / concurrent programming Git, Jira, and modern development workflows Linux / Ubuntu environments Code reviews, testing methodologies, and CI/CD practices Software design patterns (modular, scalable, fault-tolerant systems). Demonstrated ability to: Architect and deliver large-scale simulation and software systems Operate autonomously and drive projects from concept to production Define and communicate technical strategy, tradeoffs, and priorities Navigate and contribute to large, complex codebases Apply an MVP mindset while scaling solutions from prototype to production.
Senior Principal Scientist, Computational Drug Discovery – Molecular Modeling & Cheminformatics Parabilis MedicinesSenior Principal Scientist, Computational Drug Discovery – Molecular Modeling & CheminformaticsCambridge, MA$200,000–$250,000 / yearProvide computational expertise toward, but not limited to, ternary complex design for degraders and other proximity-based modalities, hit identification and prioritization, hit-to-lead progression using multi-objective optimization, initiating new projects, new drug-target assessments, and advancing drug-pipeline projects toward the clinic. We are looking for someone who can independently support project teams across the full computational spectrum, from sampling peptide conformations and designing ternary complexes to building predictive property models and running cheminformatics analyses, without needing to hand off between a dedicated 3D modeler and a dedicated cheminformatician.
Model Based Systems Engineer Actalent IncModel Based Systems EngineerWoburn, MA$52–$80 / hourWe are seeking a Model Based Systems Engineer to lead development programs through the Systems Engineering process using Model-Based Systems Engineering (MBSE) approaches that support DoD Digital Engineering goals. If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.
Senior Scientist, Advanced Ocular In Vitro Models SanofiSenior Scientist, Advanced Ocular In Vitro ModelsCambridge, MA$100.50–$145.17 / hourIntegrate automation and robotics to scale workflows and improve reproducibility, including developing automated liquid handling protocols, implementing high-throughput imaging and data acquisition systems, and optimizing robotic platforms for multi-step differentiation processes. You will work proactively across multidisciplinary teams, lead ophthalmology drug discovery programs, influence project strategies, and mentor colleagues while driving innovation in disease modeling and therapeutic evaluation.
Scientist / Engineer - Laser Modeling and Analysis Lincoln LaboratoryScientist / Engineer - Laser Modeling and AnalysisLexington, MA$145,200–$170,000 / yearThe Orion Artemis II Optical Communications System, developed by MIT Lincoln Laboratory in collaboration with NASA Goddard Space Flight Center, successfully used lasers to transmit high-definition video back to Earth as the Artemis II astronauts executed their lunar flyby. The Modeling and Analysis Team is involved with all stages of development, including developing initial understanding of novel concepts, the generation of performance predictions to inform hardware-development programs, and the design of detailed models of existing systems.
Senior Engineer, XBAT Simulation Modeling (R4546) (TX/SD/BOS) Shield AI IncSenior Engineer, XBAT Simulation Modeling (R4546) (TX/SD/BOS)Boston, MA$105,000–$155,000 / yearYou'll design, build, and scale novel aircraft subsystem models, develop infrastructure that enables automated testing for our XBAT product line, and perform verification and validation of simulation pipelines. As a Senior Modeling & Simulation Engineer, you will be dedicated to Shield AI's next-generation aircraft program, contributing to our modeling and simulation tooling pipeline.
NewSr. Energy Analyst - Infrastructure Modeling, Analytics & Demand Response Digital Realty Trust IncSr. Energy Analyst - Infrastructure Modeling, Analytics & Demand ResponseBoston, MA$110,000–$137,500 / yearPlatformDIGITAL, the company's global data center platform, provides customers with a secure data meeting place and a proven Pervasive Datacenter Architecture (PDx) solution methodology for powering innovation and efficiently managing Data Gravity challenges. This position leverages data-driven analytics to improve operational efficiency, enhance sustainability initiatives, monetize existing infrastructure assets, and accelerate site readiness while partnering closely with internal stakeholders, utilities, and external service providers.