Common clinical conditions include acute respiratory failure, sepsis, acute renal failure, hypertensive crisis, diabetic ketoacidosis, drug overdose, severe gastrointestinal bleeding, acute coronary syndromes, cerebrovascular accident, status epilepticus, post-cardiac-arrest care, multiple system organ failure, and complex fluid, electrolyte, and metabolic disorders. Additional responsibilities may include arterial line management, central line care, blood product administration, chest tube care, continuous sedation management, renal failure management, high-flow oxygen therapy, infection prevention, dysrhythmia management, and emergency medication administration.