Scientist/Sr. Scientist, DMPK General ProximityScientist/Sr. Scientist, DMPKSan Francisco, CAThese include non-linear and dose-dependent pharmacokinetics arising from ternary complex formation, linker and warhead metabolic soft spots, high molecular weight and physicochemical complexity affecting permeability and oral bioavailability, tissue distribution considerations for proteasome-engaging degraders, and the interpretation of hook-effect phenomena in in vitro and in vivo settings. Familiarity with AI/ML-based ADME prediction tools and an interest in integrating computational approaches (e.g., ML-driven metabolic stability or permeability models, digital twins for PK simulation) into the DMPK workflow alongside established platforms such as Simcyp and GastroPlus.
Scientist/Sr. Scientist, Computational Chemistry General ProximityScientist/Sr. Scientist, Computational ChemistrySan Francisco, CAThis person should not be an isolated modeler, but a true project partner who sits with chemistry teams, understands the design problem, proposes molecules, helps interpret data, and contributes tools that make the broader organization faster and smarter. This role will help drive small-molecule drug discovery programs by providing practical modeling support, applying modern computational workflows, and using the cheminformatics and AI-enabled tools that empower medicinal chemists and project teams.
Senior Scientist - Experimental Protein Design for Target Discovery Amgen IncSenior Scientist - Experimental Protein Design for Target DiscoverySouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this vital role you will build and lead high-throughput platforms for binder generation, translating computational protein designs into experimentally validated minibinders and antibodies across diverse pre-discovery targets.
Senior Scientist - Translational Safety & Risk Sciences (TSRS) Amgen IncSenior Scientist - Translational Safety & Risk Sciences (TSRS)South San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Senior Scientist - Translational Safety & Risk Sciences (Tsrs) Amgen Inc.Senior Scientist - Translational Safety & Risk Sciences (Tsrs)South San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Principal Scientist, Inflammation Amgen Inc.Principal Scientist, InflammationSouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Familiarity with small and large molecule drug discovery, mechanism of action studies, ELISA, MSD, and flow cytometry-based immune cell profiling, single-cell RNA sequencing (scRNA-Seq), CRISPR/Cas9, and omics data analysis experience a plus.
Senior Scientist - Experimental Protein Design For Target Discovery Amgen Inc.Senior Scientist - Experimental Protein Design For Target DiscoverySouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this vital role you will build and lead high-throughput platforms for binder generation, translating computational protein designs into experimentally validated minibinders and antibodies across diverse pre-discovery targets.
Associate Scientist Discovery Proteomics Amgen IncAssociate Scientist Discovery ProteomicsSouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Responsibilities will include: Execute and optimize established proteomics workflows, including sample preparation, peptide fractionation, liquid chromatography, and mass spectrometry acquisition for discovery and targeted approaches such as DIA, TMT, label-free DDA and PRM.
Senior Clinical Laboratory Scientist (Sat - Tue 6am - 4:30pm) 4x10 Schedule - Onsite Guardant HealthSenior Clinical Laboratory Scientist (Sat - Tue 6am - 4:30pm) 4x10 Schedule - OnsiteRedwood City, CaliforniaAs a Senior Clinical Laboratory Scientist, you are responsible for performing high complexity laboratory testing (next generation sequencing) on patient specimens, performing quality control and quality assurance procedures, and reporting patient results. Founded in 2012, Guardant® is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics.
Senior Clinical Laboratory Scientist (Sat - Tue 6Am - 4:30Pm) 4X10 Schedule - Onsite Guardant Health, Inc.Senior Clinical Laboratory Scientist (Sat - Tue 6Am - 4:30Pm) 4X10 Schedule - OnsiteRedwood City, CA$63–$87 / hourAs a Senior Clinical Laboratory Scientist, you are responsible for performing high complexity laboratory testing (next generation sequencing) on patient specimens, performing quality control and quality assurance procedures, and reporting patient results. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics.
Sr Scientist II, Computational Discovery Science TempusSr Scientist II, Computational Discovery ScienceRedwood City, CA$145,000–$190,000 / yearUtilize the LLM-orchestrated Tempus Loop Agent architecture to autonomously prioritize In partnership with Tempus' modeling lab, use data from CRISPR and cell perturbation experiments in patient-derived organoids to identify and validate novel targets. Leadership & Independent Contribution: Independently execute complex translational or real-world evidence research projects integrating molecular and clinical data from the Tempus multimodal data platform.
Sr Scientist II, Computational Discovery Science Tempus AI IncSr Scientist II, Computational Discovery ScienceRedwood City, CA$145,000–$190,000 / yearUtilize the LLM-orchestrated Tempus Loop Agent architecture to autonomously prioritize In partnership with Tempus' modeling lab, use data from CRISPR and cell perturbation experiments in patient-derived organoids to identify and validate novel targets. Leadership & Independent Contribution: Independently execute complex translational or real-world evidence research projects integrating molecular and clinical data from the Tempus multimodal data platform.
NewSenior Scientist - PKDM-BA Amgen IncSenior Scientist - PKDM-BASouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. The responsibilities of the successful candidate will be to design and execute biological and/or biophysical experiments to understand the ADME properties of large molecule therapeutics (and non-traditional small molecule therapies) in support of both drug discovery and early development programs.
Bioinformatics Scientist CareTechProsBioinformatics ScientistSan Francisco, CaliforniaThis role involves designing and implementing computational methods to analyze complex biological data, supporting data-driven insights in genomics, transcriptomics, and other omics fields. The ideal candidate will have experience in bioinformatics, strong programming skills, and a passion for discovering biological insights that can drive scientific and clinical progress.
Scientist II, Delivery for Large Gene Insertion Profluent IncScientist II, Delivery for Large Gene InsertionEmeryville, CA$144,000–$160,000 / yearFounded in 2022 and headquartered in Emeryville, CA, Profluent is backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures and has raised over $150M to date. The ideal candidate will have a strong track record of engineering molecular systems for mammalian cells, with expertise in gene editing, nucleic acid biochemistry, protein-nucleic acid engineering, or molecular virology.
NewSenior Scientist - Pkdm-Ba Amgen Inc.Senior Scientist - Pkdm-BaSouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. The responsibilities of the successful candidate will be to design and execute biological and/or biophysical experiments to understand the ADME properties of large molecule therapeutics (and non-traditional small molecule therapies) in support of both drug discovery and early development programs.
Clinical Lab Scientist HLA Lab (Night Shift) Stanford Health CareClinical Lab Scientist HLA Lab (Night Shift)PALO ALTO, CA$59.21–$78.43 / hourStanford Blood Center''s Histocompatibility Lab seeks a Clinical Laboratory Scientist to perform highly complex human histocompatibility testing for organ transplantation in our serological laboratory. Strictly observe privacy and security related policies, procedures and practices to preserve the integrity and confidentiality of medical and other sensitive information pertaining to donors, patients, research subjects, and employees.
Technical Director - Biological Resources GHD Group Pty LtdTechnical Director - Biological ResourcesConcord, CA$147,000–$245,000 / yearCommunity of Practice Management: Contribute strongly on a strategically significant area to a community of practice in a defined area of expertise or consulting, or lead on an area of expertise or consulting practice, to contribute to thought leadership and to develop innovative practice among colleagues. The ideal candidate must be recognized as an industry leader and have significant experience in wildlife biology, botany and/or wetland science; business development; contributing to growth of practice areas; overseeing the environmental review process; and winning and leading projects of importance.
Senior Principal Scientist -Bioanalytical Assay- Cell Therapy Genentech IncSenior Principal Scientist -Bioanalytical Assay- Cell TherapySouth San Francisco, CAD. in Immunology, Cell Biology, Biochemistry, Pharmacology, Bioanalytical Sciences, or a related life sciences discipline with a minimum of 7 years' experience in the field of drug discovery or development with extensive biopharmaceutical industry experience leading bioanalytical strategy across discovery, translational research, and clinical development. Opportunity: As an integral member of our dynamic team, you will: Define and drive the bioanalytical strategy supporting the Cell Therapy portfolio, establishing integrated, fit-for-purpose data strategies that generate the evidence needed to answer key scientific questions and inform development and portfolio decisions.
Senior Applied Research Scientist, Multimodal Foundation Models - Healthcare NVIDIA CorpSenior Applied Research Scientist, Multimodal Foundation Models - HealthcareSanta Clara, CAYou will collaborate with researchers, engineers, healthcare organizations, and industry partners to evaluate new ideas and translate successful research into software, models, and workflows that can be used by the broader healthcare ecosystem. What we need to see: PhD in Computer Science, Machine Learning, Biomedical Engineering, Computational Biology, Electrical Engineering, or a related quantitative field (or equivalent experience).