Research Assistant – Automated Organic Synthesis OnepotResearch Assistant – Automated Organic SynthesisSouth San Francisco, CaliforniaAutomated Synthesis Execution: Set up and run organic synthesis reactions using robotic liquid-handling systems (e.g., Opentrons OT-2), including sensitive reactions under inert conditions (glovebox, Schlenk lines) and photochemical reactions. Protocol & Software Development: Assist in writing and refining Python or Bash scripts for automating laboratory workflows, data parsing, plate mapping, and instrument control.
Medicinal Chemist Inductive Bio IncMedicinal ChemistSan Francisco, CA$210,000–$250,000 / yearWe are seeking an accomplished Medicinal Chemist to play a key role in building an AI-forward drug discovery platform that impacts all stages of the Design-Make-Test-Analyze cycle, and deploy that platform to dozens of programs across the industry! Through partnerships with CROs, we also offer innovative synthesis approaches, direct-to-dose testing, and cost-effective tier 1 ADME panels that enable initial human PK projection, closing the loop from computational design to experimental validation.
Field Chemist II Republic Services IncField Chemist IISan Jose, CA$39.35–$54.12 / hourPOSITION SUMMARY: The Environmental Field Chemist II role works both indoors and outdoors at various customer sites as a proficient partner to the team to lead safety protocols, package all materials based on required regulations, including onsite testing of suspected materials, and work with the customer to add additional services. Required skills include performing proper waste sampling; creating accurate waste characterizations and profiles; addressing difficult situations in a constructive manner; utilizing computer technology for communication, data gathering and reporting; negotiation and problem solving.
Chemist Intern (Bachelors/Masters - Santa Clara, CA) Applied Materials IncChemist Intern (Bachelors/Masters - Santa Clara, CA)Santa Clara, CAIf you would like to contact us regarding accessibility of our website or need assistance completing the application process, please contact us via e-mail at Accommodations_Program@amat.com, or by calling our HR Direct Help Line at 877-612-7547, option 1, and following the prompts to speak to an HR Advisor. The salary offered to a selected candidate will be based on multiple factors including location, hire grade, job-related knowledge, skills, experience, and with consideration of internal equity of our current team members.
Staff Scientist II - Medicinal Chemistry Protagonist Therapeutics IncStaff Scientist II - Medicinal ChemistryNewark, CA$135,000–$145,000 / yearThe Company also has a number of preclinical stage drug discovery programs addressing clinically and commercially validated targets including an oral IL-17 peptide antagonist, obesity dual and triple agonists, an oral hepcidin functional mimetic, and the recently announced IL-4 and amylin programs. The base pay range for this position at commencement of employment is expected to be between $135,000 and $145,000/year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.
Director, Medicinal Chemistry Protagonist Therapeutics IncDirector, Medicinal ChemistryNewark, CA$210,000–$250,000 / yearThe Discovery Chemistry team at Protagonist Therapeutics is seeking a highly motivated and experienced Director of Medicinal Chemistry to lead and manage a competent chemistry group in small molecule and peptide drug discovery against a diverse range of therapeutic targets. The Company also has a number of preclinical stage drug discovery programs addressing clinically and commercially validated targets including an oral IL-17 peptide antagonist, obesity dual and triple agonists, an oral hepcidin functional mimetic, and the recently announced IL-4 and amylin programs.
Principal Scientist, Medicinal Chemistry Genentech IncPrincipal Scientist, Medicinal ChemistrySouth San Francisco, CA$144,000–$269,100 / yearIn addition to close collaboration with other chemists, the candidate will engage with various functions such as Drug Metabolism and Pharmacokinetics, Structural Biology, Biochemical and Cellular Pharmacology, Machine Learning, Pharmaceutical Sciences, Safety and disease area Biology. You will demonstrate extensive experience and record of accomplishment in one or more of the following areas: medicinal chemistry, methodology/catalysis, total synthesis, chemical biology and physical organic chemistry.
Scientist, Medicinal Chemistry General ProximityScientist, Medicinal ChemistrySan Francisco, CAYour responsibilities will include designing and optimizing first-in-class bifunctional molecules, assessing SAR to inform iterative medicinal chemistry optimization, supervising synthetic efforts with CRO partners, performing and analyzing in cellulo assays, collaborating with our Drug Discovery and IP teams on patent applications, and contributing mechanistic insight on lead drug molecules. Chemical biology techniques including mammalian cell culture, cell-based assays (e.g., cytotoxicity, transfections, stable cell line generation, co-IP), and PPI assays (e.g., BRET, APEX/BioID, AlphaScreen); computational chemistry experience also welcomed.
Scientist, Peptide Chemistry Calico Life Sciences LLCScientist, Peptide ChemistrySouth San Francisco, CA$135,000–$145,000 / yearInnovate Synthetic Workflows: Onboard and optimize novel chemistries for high-throughput, automated peptide synthesis; troubleshoot complex synthetic challenges to generate high-quality leads, and curate a custom library of building blocks. Calico's highly innovative technology labs, its commitment to curiosity-driven discovery science, and, with academic and industry partners, its vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs.
SRA DNA Encoded Library Technology - Brisbane, CA Nurix Therapeutics IncSRA DNA Encoded Library Technology - Brisbane, CABrisbane, CA$101,690–$116,226 / yearWe are seeking a talented and motivated chemist to join our Discovery Chemistry team and contribute to the design and synthesis of DNA-encoded libraries (DELs). Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine's next chapter with a new script to outmatch disease.
Head of Computational Chemistry General ProximityHead of Computational ChemistrySan Francisco, CAThis role will drive small-molecule drug discovery programs by providing strategic and practical modeling support, implementing modern computational workflows, and building the cheminformatics and AI-enabled infrastructure needed to empower medicinal chemists and project teams. The successful candidate will be both a scientific leader and a hands-on drug designer: someone who can partner closely with medicinal chemists, structural biologists, biologists, and DMPK scientists to guide compound design from hit identification through lead optimization and candidate selection.
Director, Chemical Development Cytokinetics IncDirector, Chemical DevelopmentSouth San Francisco, CA$217,710–$253,995 / yearYou will play a key role in advancing our drug development programs by leading efforts in synthetic route design, process optimization, control strategy development, and scale-up and GMP manufacturing activities at external CDMO partners. Cytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction.
Adjunct Professor - Chemistry Lab University of San FranciscoAdjunct Professor - Chemistry LabSan Francisco, CAFor the fall 2026 semester, all courses will begin on Tuesday August 25 and end on Wednesday December 9.There are no classes on the following weeks: Week of August 24 (first week of class). Job Summary: The Department of Chemistry (https://www.usfca.edu/) invites applications to teach undergraduate laboratory courses in the fall 2026 semester.
NewLabs FSP Associate Scientist - Synthetic Chemistry Thermo Fisher Scientific IncLabs FSP Associate Scientist - Synthetic ChemistrySouth San Francisco, CA$30–$34 / hourWithin our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to leverage the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits. Summarized Purpose: Thermo Fisher is seeking a highly motivated and talented researcher with a proven track record of laboratory achievements to join our Department of Synthetic Molecule Process Chemistry.
Principal Scientist, Peptide Therapeutics Genentech IncPrincipal Scientist, Peptide TherapeuticsSouth San Francisco, CA$143,200–$265,900 / yearSynthetic Mastery: Utilize expert-level skills in solid-phase peptide synthesis, solution-phase organic chemistry, and specialized macrocyclization or ligation strategies. In this lab-based leadership role, you will combine hands-on synthetic expertise with strategic oversight, driving the discovery and optimization of peptide therapeutics across the full development lifecycle.
NewPostdoctoral Scientist, Medicinal Chemistry Eli Lilly and CoPostdoctoral Scientist, Medicinal ChemistrySouth San Francisco, CA$58,000–$123,200 / yearOur current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL). Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve.
Senior Scientist, Process Chemistry ORIC Pharmaceuticals IncSenior Scientist, Process ChemistrySouth San Francisco, CA$175,000–$200,000 / yearORIC's clinical stage product candidates include (1) ORIC-944, an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) ORIC-114, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. PhD in organic chemistry with at least 3 years for Senior Scientist and with 0-2 years' experience for a scientist of relevant hands-on pharmaceutical/biotech industry experience in the field of new drug development.
Chemistry - Graduates - AI Training - San Francisco, US Prolific Academic LtdChemistry - Graduates - AI Training - San Francisco, USSan Francisco, CAWe're looking for Chemistry Experts and Chemical Engineers to join our Expert Network to help train and evaluate cutting-edge AI models using real-world chemical expertise. We've built a unique platform that connects researchers and companies with a global pool of participants, enabling the collection of high-quality, ethically sourced human behavioural data and feedback.
Chemistry - Graduates - AI Training - San Jose, US Prolific Academic LtdChemistry - Graduates - AI Training - San Jose, USSan Jose, CAWe're looking for Chemistry Experts and Chemical Engineers to join our Expert Network to help train and evaluate cutting-edge AI models using real-world chemical expertise. We've built a unique platform that connects researchers and companies with a global pool of participants, enabling the collection of high-quality, ethically sourced human behavioural data and feedback.
Senior Scientist II, Drug Substance Revolution MedicinesSenior Scientist II, Drug SubstanceRedwood City, CaliforniaThe company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Playing a critical role as a technical lead within the Drug Substance function, the position will be responsible for process research and development and scale-up of manufacturing in support of Revolution Medicines’ pipeline compound development, clinical programs and commercial readiness.
Director, Drug Substance Revolution MedicinesDirector, Drug SubstanceRedwood City, CaliforniaThe company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Playing a critical role as a technical lead within the Drug Substance function, the position will be responsible for process research and development and scale-up of manufacturing in support of Revolution Medicines’ pipeline compound development, clinical programs and commercial readiness.
Director, Drug Substance Revolution Medicines IncDirector, Drug SubstanceRedwood City, CA$211,000–$264,000 / yearThe company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. The Opportunity: Playing a critical role as a technical lead within the Drug Substance function, the position will be responsible for process research and development and scale-up of manufacturing in support of Revolution Medicines' pipeline compound development, clinical programs and commercial readiness.
Senior Scientist II, Drug Substance Revolution Medicines IncSenior Scientist II, Drug SubstanceRedwood City, CA$170,000–$212,000 / yearThe company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. The Opportunity: Playing a critical role as a technical lead within the Drug Substance function, the position will be responsible for process research and development and scale-up of manufacturing in support of Revolution Medicines' pipeline compound development, clinical programs and commercial readiness.
NewPatent Agent / Patent Attorney – Biotechnology (IP) #22124 San Francisco Vanguard-IPPatent Agent / Patent Attorney – Biotechnology (IP) #22124 San FranciscoSan Francisco, CAThe ideal candidate will have prior experience drafting and prosecuting patent applications in the fields of synthetic organic chemistry, biochemistry, and pharmaceutical sciences. Our sole focus on intellectual property enables us to more deeply understand our clients' technical needs, and our candidates' individual talents and career interests.
Senior Scientist I Cytokinetics IncSenior Scientist ISouth San Francisco, CA$162,000–$189,000 / yearCytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction. Serve on cross functional project teams and collaborate with team members from Analytical Development, Formulation Development, and External Manufacturing to develop and execute a CMC strategy that aligns with the clinical development plan.
Manufacturing Associate I Vector Laboratories IncManufacturing Associate IBurlingame, CA$23.36–$28.55 / hourResponsibilities : Performs multi -step synthesis at milligram to multi gram scale Manufactures reagents and product according to established procedures Documents all manufacturing steps as they are performed using good documentation practices Performs purification of target compounds using column chromatography (normal and reversed ph ase, ion -exchange) and automated procedures Understands and interprets analytical results (HPLC, UV -vis, TLC) Performs routine reagent preparation for inventory and finished goods Performs in -process testing as required Maintains production equipment and facilities in clean, good working condition Works with hazardous materials following specified safety precautions Maintains a clean, orderly and safe laboratory environment following health and safety guidelines Performs other duties as assigned Employee Job Description 6737 Mowry Avenue Newark, CA 94560 vectorlabs.com 0 - 3 years of related experience or equivalent combination of education and experience Ability to accurately and efficiently follow directions Ability to work well under pressure and time constraints while maintaining a high level of work quality Abilit y to work with chemicals and organic solvents materials Ability to effectively communicate verbally and in writing Ability to lift 50 lbs.
R&D Scientist III Thermo Fisher Scientific IncR&D Scientist IIIFremont, CA$100,000–$133,300 / yearAt least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy. Contribute to the development of high-quality assay reagents by designing and executing synthetic routes for haptens, adducts, and related intermediates.
Scientist/Sr. Scientist, Medicinal Chemistry General ProximityScientist/Sr. Scientist, Medicinal ChemistrySan Francisco, CAPROTACs or other IPMs)Contributing to hit-to-lead and lead optimization studiesMed-chem optimizations: SAR, PK/PD, strong understanding of DMPKApplicant must have experience with chemical biology techniques such as mammalian cell culture and cell-based assays (e.g., cytotoxicity assays, transfections, stable cell line generation, co-immunoprecipitation), PPI assays (e.g., BRET, APEX/BioID, AlphaScreen), or strong experience in computational chemistryNice to have:Proficiency in HTS and phenotypic assay developmentProteomics experience: PTM analysis, chemo-proteomic target deconvolution, etc. Your responsibilities will include: supervising synthetic efforts with our CROs, performing and analyzing in cellulo assays, designing and optimizing first-in-class bifunctional molecules, collaborating with our Drug Discovery and IP team on patent applications, providing input for mechanistic studies on lead drug molecules, and spearheading forays into new disease areas.
Principal Scientist, Analytical Chemistry Revolution Medicines IncPrincipal Scientist, Analytical ChemistryRedwood City, CA$190,000–$238,000 / yearThe company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Design and implementation of discovery analytics, analytical data integration through collaboration with LabOS team, Data Sciences and Data Analytics functions to develop and implement automated high-throughput analytical methods that enhance efficiency and data quality.
Partner Implementation Manager UncountablePartner Implementation ManagerSan Francisco, New YorkThat means serving as the resident expert partners turn to when configurations get complex, building the training and enablement infrastructure that sets them up for success, and maintaining a quality bar that protects Uncountable's reputation and customer relationships at scale. Scientific credibility in a strategic role: This is a rare opportunity to apply genuine scientific expertise in a role with strategic scope — you're not just configuring platforms, you're building the infrastructure that makes partner-delivered implementations succeed.
Scientific Implementation Associate UncountableScientific Implementation AssociateSan Francisco, New YorkYou'll spend time restructuring and contextualizing real customer datasets, designing data models that capture complex experimental relationships, and iterating on configurations in close collaboration with scientists and engineers. A rare entry point: This role gives scientists a path into the tech industry that doesn't require abandoning their domain expertise — you'll use your scientific knowledge every day, and deepen it across new fields.
Scientific Implementation Manager UncountableScientific Implementation ManagerSan Francisco, New YorkScientific depth: A meaningful background in chemistry, materials science, biology, chemical engineering, or a closely related field — you should be comfortable discussing experimental design, data types, and R&D workflows with PhD-level researchers. M.S. or higher in chemistry, materials science, chemical engineering, biology, or a closely related field, plus 2–3 years of post-degree work experience in research, industry, or a technical customer-facing role.
Senior Product Manager, Chemistry Revolution Medicines IncSenior Product Manager, ChemistryRedwood City, CA$186,000–$233,000 / yearYou will partner with medicinal chemists, synthetic chemists, computational chemists, analytical chemists, DMPK and Biology partners, Data Science, ML Engineering, Data Engineering, IT, and platform teams to turn complex Chemistry workflows into intuitive, scalable solutions that accelerate the Design-Make-Test-Learn cycle. The company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.
Senior Product Manager, Chemistry Revolution MedicinesSenior Product Manager, ChemistryRedwood City, CaliforniaYou will partner with medicinal chemists, synthetic chemists, computational chemists, analytical chemists, DMPK and Biology partners, Data Science, ML Engineering, Data Engineering, IT, and platform teams to turn complex Chemistry workflows into intuitive, scalable solutions that accelerate the Design-Make-Test-Learn cycle. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.