In Vitro Pharmacologist - Molecule Discovery Eli Lilly and CoIn Vitro Pharmacologist - Molecule DiscoverySan Diego, CA$163,500–$281,600 / yearOur current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). They will also serve as a key ExploR&D scientific expert and consultant to biotechs, designing and executing fit-for-purpose in vitro pharmacology models to support hit selection, lead optimization, and candidate progression in partnership with biotechs, and will evaluate and build CRO networks to support and extend these capabilities.
Scientist I, Quantitative Systems Pharmacologist Revolution Medicines IncScientist I, Quantitative Systems PharmacologistRedwood City, CA$119,000–$149,000 / yearAs a Quantitative Systems Pharmacologist, you will: Develop, validate, execute, and refine quantitative systems pharmacology (QSP) models, minimal physiologically based pharmacokinetic (PBPK) models, semi-mechanistic PK/PD models, and tumor growth models to support development and discovery phase projects including next-generation inhibitor design and assessment of combination potential. This position will be responsible for developing, validating, and executing modeling projects with a focus on mechanistic PBPK-QSP mathematical models for small molecule programs to increase mechanistic understanding of compound PK behavior and drug distribution, pharmacological effects on RAS targets, support clinical translation, and drive future discovery and development efforts.
Scientist I, Quantitative Systems Pharmacologist Revolution MedicinesScientist I, Quantitative Systems PharmacologistRedwood City, CaliforniaAs a Quantitative Systems Pharmacologist, you will: Develop, validate, execute, and refine quantitative systems pharmacology (QSP) models, minimal physiologically based pharmacokinetic (PBPK) models, semi-mechanistic PK/PD models, and tumor growth models to support development and discovery phase projects including next-generation inhibitor design and assessment of combination potential. This position will be responsible for developing, validating, and executing modeling projects with a focus on mechanistic PBPK-QSP mathematical models for small molecule programs to increase mechanistic understanding of compound PK behavior and drug distribution, pharmacological effects on RAS targets, support clinical translation, and drive future discovery and development efforts.
Director, Clinical Pharmacology Les Laboratoires Servier SASDirector, Clinical PharmacologyCARemote$200,000–$255,000 / yearThe role involves strong cross-functional collaboration with internal and external partners, including Clinical Operations, Biostatistics, Data Management, Medical Writing, Regulatory, Safety, Technical Operations and regulatory agencies, to advance drug candidates in an efficient and scientifically rigorous manner. Minimum of 8 years of experience working as a clinical pharmacologist in pharmaceutical industry, research institutions and/or regulatory agencies, with a strong track record in designing, interpreting, and reporting clinical pharmacology studies.
Director, Clinical Pharmacology Revolution MedicinesDirector, Clinical PharmacologyRedwood City, CaliforniaThe company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. The amount and availability of any bonus, commission, incentive, field kit benefits, or any other form of compensation and field kit benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
Director, Clinical Pharmacology Revolution Medicines IncDirector, Clinical PharmacologyRedwood City, CA$211,000–$264,000 / yearThe company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. The amount and availability of any bonus, commission, incentive, field kit benefits, or any other form of compensation and field kit benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.
Scientist - In vivo pharmacology - Discovery Research Amgen IncScientist - In vivo pharmacology - Discovery ResearchSouth San Francisco, CAp>In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Proficiency in multiple in vivo dosing routes (IP, PO, SC, IV), diverse blood collection methods (e.g., cardiac, submental), serum/plasma processing, necropsy, perfusion techniques, IVIS imaging, and small rodent survival surgery, with a strong emphasis on animal welfare.
Scientist I In Vivo Pharmacology - Tumor Intrinsic Biology AbbVie IncScientist I In Vivo Pharmacology - Tumor Intrinsic BiologySan Francisco, CAProficient hands-on experience with in vivo tumor model study techniques, including anesthetization, biological sample collection (tumor, tissue, and blood sampling), cell/drug administration via different routes/sites (SC, IP, PO, IV), and tumor volume measurement. Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position.
NewComputational Scientist II Tailored ManagementComputational Scientist IISouth San Francisco, CA$39.03–$47.23 / hourstrong>Build & Deploy Agentic LLM WorkflowsDesign and implement LLM-powered agent frameworks that automate and enhance scientific workflows within the CPP organization. Develop Quality & Evaluation FrameworksBuild automated quality control processes to assess LLM-generated outputs for scientific accuracy, structure, and consistency.
NewComputational Scientist II Talent Software Services, Inc.Computational Scientist IISouth San Francisco, CA$48–$50 / hourPrior exposure to LLM applications is a big plus — whether through building and deploying LLM-powered pipelines, working with agentic frameworks such as LangSmith, retrieval-augmented generation (RAG) architectures, harness engineering or guardrail design, or integrating LLM APIs into functional tools. Our Clinical Pharmacology and Pharmacometrics (CPP) group is at the forefront of this effort, embedding large language model (LLM)-powered tools directly into pharmacometric workflows to accelerate scientific planning, analysis, and decision-making.
NewComputational Scientist II LanceSoft IncComputational Scientist IISouth San Francisco, CA$45–$49.63 / hourPrior exposure to LLM applications is a big plus whether through building and deploying LLM-powered pipelines, working with agentic frameworks such as LangSmith, retrieval-augmented generation (RAG) architectures, harness engineering or guardrail design, or integrating LLM APIs into functional tools. You will work at the interface of AI engineering and quantitative pharmacology, partnering closely with M&S Scientists and Clinical Pharmacologists to develop tools that are scientifically grounded, reliable, and impactful.
NewComputational Scientist II The Fountain Group LLCComputational Scientist IISouth San Francisco, CA$42–$47 / hourli>Prior exposure to LLM applications is a big plus — whether through building and deploying LLM-powered pipelines, working with agentic frameworks such as LangSmith, retrieval-augmented generation (RAG) architectures, harness engineering or guardrail design, or integrating LLM APIs into functional tools. Our Clinical Pharmacology and Pharmacometrics (CPP) group is at the forefront of this effort, embedding large language model (LLM)-powered tools directly into pharmacometric workflows to accelerate scientific planning, analysis, and decision-making.
Vice President, Translational Research Revolution Medicines IncVice President, Translational ResearchRedwood City, CA$294,000–$367,000 / yearp>The Opportunity: As a Vice President reporting to the SVP of Translational Research in Biology, the individual will collaborate with colleagues in Research and Development to serve as the scientific and organizational leader of the Cancer Pharmacology function and help shape the translational research strategy supporting Revolution Medicines'' discovery and development portfolio. The company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.
Vice President, Translational Research Revolution MedicinesVice President, Translational ResearchRedwood City, Californiap>As a Vice Presidentreporting to the SVP of Translational Research in Biology,the individual will collaborate with colleagues in Research and Development to serve as the scientific and organizational leader of the Cancer Pharmacology function and help shape the translational research strategy supporting Revolution Medicines' discovery and development portfolio. The ideal candidate will: Define and implement forward translation strategies for RAS-driven diseasessupervising an internal team of highly experienced and accomplished cancer pharmacologists to drive in vivo pharmacology in parallel with scientific discovery and combination strategies.
NewComputational Scientist II Software Guidance & AssistanceComputational Scientist IISouth San Francisco, CA$43.92–$48.92 / hourPrior exposure to LLM applications is a big plus — whether through building and deploying LLM-powered pipelines, working with agentic frameworks such as LangSmith, retrieval-augmented generation (RAG) architectures, harness engineering or guardrail design, or integrating LLM APIs into functional tools. Our Clinical Pharmacology and Pharmacometrics (CPP) group is at the forefront of this effort, embedding large language model (LLM)-powered tools directly into pharmacometric workflows to accelerate scientific planning, analysis, and decision-making.
Director, Nonclinical Safety Assessment Expert (Multiple Therapeutic Areas) Novartis AGDirector, Nonclinical Safety Assessment Expert (Multiple Therapeutic Areas)La Jolla, CA$185,500–$344,500 / yearp>Internal Title: Director#LI-HybridLocation: San Diego, CAIn this key role you will provide global, end to end nonclinical safety leadership across multiple therapeutic areas and modalities, ensuring scientifically robust, fit for purpose, and regulatory compliant safety strategies that enable successful clinical trial initiation and support registration. Essential Requirements:• Advanced scientific degree (PhD, MD, DVM, PharmD, or equivalent) in Toxicology, Pharmacology, or related discipline; or DABT; or equivalent industry experience.• 5 plus years of experience as a nonclinical safety Project Team member, preferably across multiple development phases up to registration.•
NewComputational Scientist II SGA Inc.Computational Scientist IISouth San Francisco, CAPrior exposure to LLM applications is a big plus — whether through building and deploying LLM-powered pipelines, working with agentic frameworks such as LangSmith, retrieval-augmented generation (RAG) architectures, harness engineering or guardrail design, or integrating LLM APIs into functional tools. Our Clinical Pharmacology and Pharmacometrics (CPP) group is at the forefront of this effort, embedding large language model (LLM)-powered tools directly into pharmacometric workflows to accelerate scientific planning, analysis, and decision-making.