Director, Head of Program Management Tessera Therapeutics IncDirector, Head of Program ManagementSomerville, MA$186,000–$239,000 / yearCompany Summary: Tessera Therapeutics is pioneering Gene Writing- a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Guiding and empowering Program Managers to drive the development and management of integrated program plans (including timelines, assumptions, scenarios, risks, critical path, decision maps, goals, and budget drivers).
SVP, Clinical Development Amylyx Pharmaceuticals IncSVP, Clinical DevelopmentCambridge, MARemote$416,000–$468,000 / yearThe Senior Vice President (SVP) of Clinical Development will provide strategic direction and technical leadership to the clinical development team, including clinical-regulatory development planning, clinical trial design, implementation and execution, clinical data analysis and management, and clinical competitive intelligence. Overall, the main responsibility will be to provide strategic leadership for the clinical and medical aspects for the various programs and work closely with a cross-functional team to align the clinical development plan with the overall development strategy of the relevant products.
Associate Director, Quantitative Systems Pharmacology GSK plcAssociate Director, Quantitative Systems PharmacologyWaltham, MA$151,500–$252,500 / yearAs an Associate Director of Quantitative Systems Pharmacology (QSP) Expert, you will develop and apply QSP models to guide clinical study designs and mechanistic interpretation of study results in support of development of treatments and combination of treatments for a variety of diseases and therapeutic areas. This role requires a highly motivated individual to develop and apply QSP models to guide clinical study designs and mechanistic interpretation of study results in support of development of treatments and combination of treatments for a variety of diseases and therapeutic areas.
Associate Director, Quantitative System Pharmacology Viridian Therapeutics IncAssociate Director, Quantitative System PharmacologyWaltham, MARemoteQualifications: Requires a PhD degree or equivalent with a minimum of 6+ years of combined academic and biotechnology or pharmaceutical experience in QSP/T, (m)PBPK, mathematics, chemical/biomedical engineer, physics, and/or Translational Sciences, including experience with therapeutic antibodies. Experience with QSP or (m)PBPK modeling in autoimmune or inflammation for biologicals (ie, monoclonal antibodies, or other modalities), and bring forward combination drug approaches leveraging QSP models to advance clinical trials.
Senior Director, Clinical Pharmacology Vertex Pharmaceuticals IncSenior Director, Clinical PharmacologyBoston, MA$232,000–$348,000 / yearKey Duties and Responsibilities: • Defines the scientific direction and directs the execution of clinical pharmacology plans for Disease Area programs • Provides strategic operational leadership to the Clinical Pharmacology function in collaboration with the other Disease Area Leaders • Manages a group of Clinical Pharmacologists at Director-level and below to set strategy, develop and execute Clinical Pharmacology plans and studies for Disease Area programs • Directs Clinical Pharmacology efforts for small molecule and novel modality programs, such as gene editing, gene therapy, and cell therapy, in the Disease Area • As a people manager within the organization, may have financial accountabilities and human resource responsibilities for assigned staff. D. or Pharm D (or equivalent degree) in pharmacokinetics, pharmacometrics, clinical pharmacology or translational development and 15+ years of relevant post-doctoral employment experience, or • Masters Degree (or equivalent degree) in pharmacokinetics, pharmacometrics, clinical pharmacology or translational development and 20+ years of relevant employment experience, or • Typically requires 5 years of supervisory/management experience.
Director, Clinical Pharmacology Alkermes PlcDirector, Clinical PharmacologyWaltham, MAIn 2024 and 2025, we were certified as a Great Place to Work in the U.S. and named one of Massachusetts' Top Places to Work by the Boston Globe, a Best Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma by Fortune Magazine. We have a portfolio of proprietary commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia, bipolar I disorder and narcolepsy, and a pipeline of clinical and preclinical candidates in development for various psychiatric and neurological disorders.
Associate Director, Discovery DMPK Parabilis MedicinesAssociate Director, Discovery DMPKCambridge, MA$165,000–$200,000 / yearReporting to the VP of Discovery DMPK, you will serve as the primary DMPK representative on cross-functional discovery project teams, collaborating closely with medicinal chemists, pharmacologists, toxicologists and external CRO partners to advance novel therapeutics from early discovery through DC nomination. We are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options.
Clinical Research Director - Rare Diseases SanofiClinical Research Director - Rare DiseasesCambridge, MA$178,500–$257,833.33 / yearExperience / Skills: MD or MD/PhD in a relevant scientific discipline, preferably pulmonology, with at least 2 years relevant experience in clinical development within the pharmaceutical industry, academia, or government agencies such as the NIH, FDA, or other equivalent national or international public health and regulatory organization. On Clinical Development, the CRD: Designs the global clinical development strategy (in close cooperation with other members of the team, particularly Regulatory Affairs end Health Economics) and leads the clinical development with regard to ongoing development activities and planned LCM for labelling changes.
Scientist I/II, Bioanalytical LC-MS Tessera Therapeutics IncScientist I/II, Bioanalytical LC-MSSomerville, MA$109,000–$143,000 / yearDevelop, optimize, and validate bioanalytical methods to measure proteins, oligos, and lipids in biological samples, including cells, biofluids, and tissues, to support the development of discovery, preclinical and clinical programs. Company Summary: Tessera Therapeutics is pioneering Gene Writing- a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source.
Senior Research Associate, Novel Delivery Technologies Contract Tessera Therapeutics IncSenior Research Associate, Novel Delivery Technologies ContractSomerville, MA$44–$50 / hourCompany Summary: Tessera Therapeutics is pioneering Gene Writing- a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. The submission of unsolicited resumes by recruitment or staffing agencies to Tessera Therapeutics or its employees is strictly prohibited unless contacted directly by Tessera Therapeutics' internal Talent Acquisition team.
Director, Nonclinical Safety Assessment Expert (Multiple Therapeutic Areas) Novartis AGDirector, Nonclinical Safety Assessment Expert (Multiple Therapeutic Areas)Cambridge, MA$185,500–$344,500 / yearInternal Title: Director #LI-Hybrid Location: Cambridge, MA USA In this key role you will provide global, end to end nonclinical safety leadership across multiple therapeutic areas and modalities, ensuring scientifically robust, fit for purpose, and regulatory compliant safety strategies that enable successful clinical trial initiation and support registration. You will be a critical enabler of portfolio progression, providing authoritative nonclinical safety leadership, regulatory credibility with Health Authorities, and strategic integration across therapeutic areas and modalities.