NewAssociate Director / Director, Quantitative Systems Pharmacologist Lead GSK plcAssociate Director / Director, Quantitative Systems Pharmacologist LeadWaltham, MA$188,100–$313,500 / yearSought after experiences for this position include building mechanistic mathematical models and leveraging knowledge in the areas of scientific ML, inverse problems, AIML and/or statistical methodologies, to enhance the robustness and quality of model development to leverage for decision-making from exploratory research through clinical development. In addition, you will be defining, implementing and coordinating QSP and QST related Clinical Pharmacology and Quantitative Medicine development strategies for disease and therapeutics of interest, and providing expert input into the clinical pharmacology evidence generation and integrated evidence plans in the Disease therapeutic area.
In Vitro Pharmacologist - Molecule Discovery Eli Lilly and CoIn Vitro Pharmacologist - Molecule DiscoveryBoston, MA$163,500–$281,600 / yearOur current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). They will also serve as a key ExploR&D scientific expert and consultant to biotechs, designing and executing fit-for-purpose in vitro pharmacology models to support hit selection, lead optimization, and candidate progression in partnership with biotechs, and will evaluate and build CRO networks to support and extend these capabilities.
Pharmacometrician & Systems Pharmacologist Pfizer IncPharmacometrician & Systems PharmacologistCambridge, MA$106,000–$176,600 / yearSubject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. The Pharmacometrics & Systems Pharmacology (PSP) group is seeking a highly motivated quantitative scientist to support the Internal Medicine portfolio through the application of model-informed drug development (MIDD).
Director, Head of Program Management Tessera Therapeutics IncDirector, Head of Program ManagementSomerville, MA$186,000–$239,000 / yearCompany Summary: Tessera Therapeutics is pioneering Gene Writing- a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Guiding and empowering Program Managers to drive the development and management of integrated program plans (including timelines, assumptions, scenarios, risks, critical path, decision maps, goals, and budget drivers).
NewSVP, Clinical Development Amylyx Pharmaceuticals IncSVP, Clinical DevelopmentCambridge, MARemote$416,000–$468,000 / yearp>The Senior Vice President (SVP) of Clinical Development will provide strategic direction and technical leadership to the clinical development team, including clinical-regulatory development planning, clinical trial design, implementation and execution, clinical data analysis and management, and clinical competitive intelligence. Overall, the main responsibility will be to provide strategic leadership for the clinical and medical aspects for the various programs and work closely with a cross-functional team to align the clinical development plan with the overall development strategy of the relevant products.
NewExecutive Director, Oncology Translational Medicine, Clinical Pharmacology Modeling and Simulation GSK plcExecutive Director, Oncology Translational Medicine, Clinical Pharmacology Modeling and SimulationWaltham, MAThe incumbent will act as a subject matter expert, working closely with the VP, Head of Oncology Clinical Pharmacology, Modeling and Simulation and the Oncology Translational Medicine leadership to provide scientific leadership in trial design, data interpretation, and aid in global harmonization of pre-clinical execution and reporting. input on development of efficient and effective modeling and simulation strategies, including population PK, exposure-response analysis, and physiologically based PK (PBPK) to support clinical trial design, justification of dosing regimen, and provide supportive evidence of efficacy and safety for regulatory submissions.
Senior Director, Clinical Pharmacology Vertex PharmaceuticalsSenior Director, Clinical PharmacologyBoston, MassachusettsAs a Disease Area leader, the Senior Director, Clinical Pharmacology will direct Clinical Pharmacology efforts for small molecule, large molecule, and novel modality programs, such as gene editing, gene therapy, and cell therapy, in the Disease Area. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Director, Clinical Pharmacology Alkermes PlcDirector, Clinical PharmacologyWaltham, MAIn 2024 and 2025, we were certified as a Great Place to Work in the U.S. and named one of Massachusetts' Top Places to Work by the Boston Globe, a Best Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma by Fortune Magazine. We have a portfolio of proprietary commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia, bipolar I disorder and narcolepsy, and a pipeline of clinical and preclinical candidates in development for various psychiatric and neurological disorders.
Postdoctoral Associate, Pharmacology, Physiology & Biophysics, Chobanian & Avedisian School of Medicine Boston UniversityPostdoctoral Associate, Pharmacology, Physiology & Biophysics, Chobanian & Avedisian School of MedicineBoston, MA$65,000–$70,000p>The TCW laboratory (https://sites.bu.edu/tcwlab/) in the Department of Pharmacology, Physiology & Biophysics at Boston University Chobanian & Avedisian School of Medicine in Boston, Massachusetts is looking for highly motivated and skilled stem cell biologists or electrophysiologists to be the drivers of our efforts to translate the genetics of human AD toward therapeutic interventions. Interested candidates should submit a cover letter outlining their research interests and career goals, a current CV, and contact information for three references to Dr. Julia TCW, Assistant professor and Director [juliatcw@bu.edu] or https://sites.bu.edu/tcwlab/talent-aquisition/..
Pioneering Medicines: Vice President / Senior Vice President - Head of Biology Invitro and InVivo Pharmacology Flagship Pioneering IncPioneering Medicines: Vice President / Senior Vice President - Head of Biology Invitro and InVivo PharmacologyCambridge, MA$252,000–$410,000 / yearp>Flagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company's annual list of the World's Most Innovative Companies. Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Research Scientist - CardioMetabolic Research Net2SourceResearch Scientist - CardioMetabolic ResearchBoston, MA$74.83–$88.04 / hourThe ideal candidate should possess a solid background in cell culture and cell-based functional assays, playing an essential role in advancing our discovery initiatives and pipeline projects centered on anti-obesity therapeutics. • Development of cell-based functional assays, biochemical and enzymatic assays and screening of Client therapeutics in 96-/384-well plate formats at a single concentration or in a concentration/response manner.
Histology and 3D In Vitro Models Scientist Eurofins Scientific SEHistology and 3D In Vitro Models ScientistCambridge, MA$100,000–$105,000 / yearp>Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier, and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic, and labelling is accurate.
Sr. Scientist, DMPK Centessa Pharmaceuticals PlcSr. Scientist, DMPKBoston, MA$160,000–$180,000 / yearCentessa is seeking a Senior Scientist in Discovery DMPK to partner with pharmacologists and medicinal chemists to support the identification of lead candidates with optimal DMPK properties for potential progression into development. Centessa Pharmaceuticals plc (Nasdaq: CNTA) new kind of pharmaceutical company with a deconstructed R&D environment that prioritizes data driven decision making led by subject matter experts.
Associate Director, Discovery DMPK Parabilis MedicinesAssociate Director, Discovery DMPKCambridge, MA$165,000–$200,000 / yearIts lead asset, zolucatetide (FOG-001), is a first-in-class, clinically validated direct inhibitor of the interaction between ß-catenin and the T-cell factor (TCF) family of transcription factors, implicated in millions of cancer cases annually, including in colorectal cancer, desmoid tumors, hepatocellular carcinoma and a range of other Wnt/ß-catenin-driven tumors. Reporting to the VP of Discovery DMPK, you will serve as the primary DMPK representative on cross-functional discovery project teams, collaborating closely with medicinal chemists, pharmacologists, toxicologists and external CRO partners to advance novel therapeutics from early discovery through DC nomination.
Clinical Research Director - Rare Diseases SanofiClinical Research Director - Rare DiseasesCambridge, MA$178,500–$257,833.33 / yearp>Experience / Skills: MD or MD/PhD in a relevant scientific discipline, preferably pulmonology, with at least 2 years relevant experience in clinical development within the pharmaceutical industry, academia, or government agencies such as the NIH, FDA, or other equivalent national or international public health and regulatory organization. On Clinical Development, the CRD: Designs the global clinical development strategy (in close cooperation with other members of the team, particularly Regulatory Affairs end Health Economics) and leads the clinical development with regard to ongoing development activities and planned LCM for labelling changes.
Director, Nonclinical Safety Assessment Expert (Multiple Therapeutic Areas) Novartis AGDirector, Nonclinical Safety Assessment Expert (Multiple Therapeutic Areas)Cambridge, MA$185,500–$344,500 / yearp>Internal Title: Director #LI-Hybrid Location: Cambridge, MA USA In this key role you will provide global, end to end nonclinical safety leadership across multiple therapeutic areas and modalities, ensuring scientifically robust, fit for purpose, and regulatory compliant safety strategies that enable successful clinical trial initiation and support registration. You will be a critical enabler of portfolio progression, providing authoritative nonclinical safety leadership, regulatory credibility with Health Authorities, and strategic integration across therapeutic areas and modalities.
Director - Clinical Research Scientist Eli Lilly and CoDirector - Clinical Research ScientistBoston, MA$193,500–$338,800 / yearOur current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Organization Overview: Verve, a wholly owned subsidiary of Eli Lilly, is seeking a Senior Director - Clinical Research Scientist (CRS) to help lead clinical trial efforts for our innovative gene editing therapies targeting cardiovascular disease.
Executive Medical Director - Physician -Early Clinical Development, Immunology Eli Lilly and CoExecutive Medical Director - Physician -Early Clinical Development, ImmunologyBoston, MA$265,500–$389,400 / yearOur current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). The successful candidate will serve as a strategic and scientific leader, connecting discovery scientists, translational/biomarker experts, early clinical physicians, clinical pharmacologists, and late-stage clinicians to craft compelling therapeutic hypotheses and efficiently test them in early clinical development with line of sight to full development and approval.