In Vitro Pharmacologist - Molecule Discovery Eli Lilly and CoIn Vitro Pharmacologist - Molecule DiscoveryBoston, MA$163,500–$281,600 / yearOur current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). They will also serve as a key ExploR&D scientific expert and consultant to biotechs, designing and executing fit-for-purpose in vitro pharmacology models to support hit selection, lead optimization, and candidate progression in partnership with biotechs, and will evaluate and build CRO networks to support and extend these capabilities.
Pharmacometrician & Systems Pharmacologist Pfizer IncPharmacometrician & Systems PharmacologistCambridge, MA$106,000–$176,600 / yearSubject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. The Pharmacometrics & Systems Pharmacology (PSP) group is seeking a highly motivated quantitative scientist to support the Internal Medicine portfolio through the application of model-informed drug development (MIDD).
Head of Translational Science Absentia LabsHead of Translational ScienceBoston, MassachusettsThey will be responsible for ensuring that our platform addresses the highest-value problems in drug development, generates evidence that customers trust, and evolves in ways that support adoption across pharmaceutical, biotechnology, and regulatory organizations. We are seeking a hands-on leader capable of connecting science, product, regulatory strategy, and customer needs to help define the adoption of AI-native safety assessment across the global drug development ecosystem.
Director, Clinical Pharmacology Crescent BiopharmaDirector, Clinical PharmacologyWaltham, Massachusetts$226,000–$250,000 / yearLead preparation and review of clinical pharmacology sections of study protocols, reports, investigators' brochures and regulatory filings (IND’s, BLA’s, etc.), and respond to regulatory inquiries related to clinical pharmacology. Drive utilization of model-based drug development approach for human PK prediction, dose and dosing regimen selection and optimization, collaborating closely with cross functional colleagues.
Senior Director, Clinical Pharmacology Vertex PharmaceuticalsSenior Director, Clinical PharmacologyBoston, MassachusettsAs a Disease Area leader, the Senior Director, Clinical Pharmacology will also direct Clinical Pharmacology efforts for small molecule and novel modality programs, such as gene editing, gene therapy, and cell therapy, in the Disease Area. The role’s responsibilities will include maintaining organizational processes across the group, influencing clinical program strategy, and integrating activities with other departments across the Global Research and Development organization, to help shape innovative and integrated clinical development plans.
Director, Clinical Pharmacology Alkermes PlcDirector, Clinical PharmacologyWaltham, MAIn 2024 and 2025, we were certified as a Great Place to Work in the U.S. and named one of Massachusetts' Top Places to Work by the Boston Globe, a Best Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma by Fortune Magazine. We have a portfolio of proprietary commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia, bipolar I disorder and narcolepsy, and a pipeline of clinical and preclinical candidates in development for various psychiatric and neurological disorders.
Postdoctoral Associate, Pharmacology, Physiology & Biophysics, Chobanian & Avedisian School of Medicine Boston UniversityPostdoctoral Associate, Pharmacology, Physiology & Biophysics, Chobanian & Avedisian School of MedicineBoston, MA$65,000–$70,000The core program is to translate AD genetics and functional genomics into human brain cells both in vitro 2D and 3D models using human induced pluripotent stem cells (hiPSCs) from population and isogenic lines generated by CRISPR/Cas9 genome editing and in vivo hiPSC/rodent chimera systems in comparison with post-mortem brain. The TCW laboratory (https://sites.bu.edu/tcwlab/) in the Department of Pharmacology, Physiology & Biophysics at Boston University Chobanian & Avedisian School of Medicine in Boston, Massachusetts is looking for highly motivated and skilled stem cell biologists or electrophysiologists to be the drivers of our efforts to translate the genetics of human AD toward therapeutic interventions.
Pioneering Medicines: Vice President / Senior Vice President - Head of Biology Invitro and InVivo Pharmacology Flagship Pioneering IncPioneering Medicines: Vice President / Senior Vice President - Head of Biology Invitro and InVivo PharmacologyCambridge, MA$252,000–$410,000 / yearFlagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company's annual list of the World's Most Innovative Companies. Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Research Scientist - CardioMetabolic Research Net2SourceResearch Scientist - CardioMetabolic ResearchBoston, MA$74.83–$88.04 / hourThe ideal candidate should possess a solid background in cell culture and cell-based functional assays, playing an essential role in advancing our discovery initiatives and pipeline projects centered on anti-obesity therapeutics. • Development of cell-based functional assays, biochemical and enzymatic assays and screening of Client therapeutics in 96-/384-well plate formats at a single concentration or in a concentration/response manner.
Associate Director, Discovery DMPK Parabilis MedicinesAssociate Director, Discovery DMPKCambridge, MA$165,000–$200,000 / yearIts lead asset, zolucatetide (FOG-001), is a first-in-class, clinically validated direct inhibitor of the interaction between ß-catenin and the T-cell factor (TCF) family of transcription factors, implicated in millions of cancer cases annually, including in colorectal cancer, desmoid tumors, hepatocellular carcinoma and a range of other Wnt/ß-catenin-driven tumors. Reporting to the VP of Discovery DMPK, you will serve as the primary DMPK representative on cross-functional discovery project teams, collaborating closely with medicinal chemists, pharmacologists, toxicologists and external CRO partners to advance novel therapeutics from early discovery through DC nomination.
Sr. Scientist, DMPK Centessa Pharmaceuticals PlcSr. Scientist, DMPKBoston, MA$160,000–$180,000 / yearCentessa is seeking a Senior Scientist in Discovery DMPK to partner with pharmacologists and medicinal chemists to support the identification of lead candidates with optimal DMPK properties for potential progression into development. Centessa Pharmaceuticals plc (Nasdaq: CNTA) new kind of pharmaceutical company with a deconstructed R&D environment that prioritizes data driven decision making led by subject matter experts.
Director, Nonclinical Safety Assessment Expert (Multiple Therapeutic Areas) Novartis AGDirector, Nonclinical Safety Assessment Expert (Multiple Therapeutic Areas)Cambridge, MA$185,500–$344,500 / yearInternal Title: Director #LI-Hybrid Location: Cambridge, MA USA In this key role you will provide global, end to end nonclinical safety leadership across multiple therapeutic areas and modalities, ensuring scientifically robust, fit for purpose, and regulatory compliant safety strategies that enable successful clinical trial initiation and support registration. You will be a critical enabler of portfolio progression, providing authoritative nonclinical safety leadership, regulatory credibility with Health Authorities, and strategic integration across therapeutic areas and modalities.
Clinical Research Director - Rare Diseases SanofiClinical Research Director - Rare DiseasesCambridge, MA$178,500–$257,833.33 / yearExperience / Skills: MD or MD/PhD in a relevant scientific discipline, preferably pulmonology, with at least 2 years relevant experience in clinical development within the pharmaceutical industry, academia, or government agencies such as the NIH, FDA, or other equivalent national or international public health and regulatory organization. On Clinical Development, the CRD: Designs the global clinical development strategy (in close cooperation with other members of the team, particularly Regulatory Affairs end Health Economics) and leads the clinical development with regard to ongoing development activities and planned LCM for labelling changes.
Director - Clinical Research Scientist Eli Lilly and CoDirector - Clinical Research ScientistBoston, MA$193,500–$338,800 / yearOur current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Organization Overview: Verve, a wholly owned subsidiary of Eli Lilly, is seeking a Senior Director - Clinical Research Scientist (CRS) to help lead clinical trial efforts for our innovative gene editing therapies targeting cardiovascular disease.
Executive Medical Director - Physician -Early Clinical Development, Immunology Eli Lilly and CoExecutive Medical Director - Physician -Early Clinical Development, ImmunologyBoston, MA$265,500–$389,400 / yearOur current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). The successful candidate will serve as a strategic and scientific leader, connecting discovery scientists, translational/biomarker experts, early clinical physicians, clinical pharmacologists, and late-stage clinicians to craft compelling therapeutic hypotheses and efficiently test them in early clinical development with line of sight to full development and approval.