Leads longitudinal pharmacotherapy management for a defined panel of high-risk patients with cardiovascular-kidney-metabolic syndrome and respiratory conditions during hospitalization and post-discharge utilizing telemedicine, remote patient monitoring, and in-person care models. Initiates, optimizes, and titrates guideline-directed medical therapy (GDMT) under collaborative drug therapy management (CDTM) agreements, with a focus on heart failure, ASCVD, diabetes, obesity, CKD, COPD, asthma, and pneumonia.