Physical Scientist Jobs in the United States
Takeda
Boston, MA
Receives high level instructions on all work, determines methods for new assignments, works closely with manager, may manage junior staff Determines methods for new assignments; perform literature search as needed to propose and develops innovative solutions. Serve as a subject matter expert in projects requiring multi-omic and multi-modal analyses from preclinical and clinical studies to identify and execute biomarker studies, patient stratification, and identify novel drugtargets/biomarkers.
Takeda
Boston, MA
You will establish novel bioinformatics and machine learning workflows to analyze next-generation sequencing data to advance antibody sequences from in vitro (yeast and phage), in vivo (single/bulk B cells) or de novo (AI based) platforms with the goal to deeply interrogate repertoires, expand functional and sequence diversity and accelerate lead discovery using in silico tools. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.
Takeda
Boston, MA
Significant experience with drug discovery applications of cell culture including immortalized cell lines, primary cell cultures, and multicellular or organoid culture models, preferably models that recapitulate cellular cross-talk in fibroinflammatory or diseased tissues. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.
Takeda
Boston, MA
Experience with a variety of computational tools and methodology including large-scale virtual screening, ligand ability analyses, homology modeling, quantum mechanics, pharmacophore elucidation, machine learning and more against common drug discovery targets (GPCRs, Kinases etc.). The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.
Takeda
Boston, MA
The Gastrointestinal and Inflammation (GI2) Drug Discovery Unit at Takeda is building a new team of experienced, innovative, and collaborative researchers to deliver an industry-leading portfolio of drugs for various gastrointestinal, autoimmune, andinflammatory diseases. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.
Takeda
Boston, MA
The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. BS with 4-6+ years of experience in an academic and/or industry setting related to immunohistochemistry, target validation, mechanism of action, pharmacodynamic, and translational strategies across different therapeutic areas (including oncology, gastrointestinal and neurology).
Takeda
Boston, MA
Your role: provides technical leadership for research project implementation and coordination, begins at the conception of new projects and helps advance to candidate selection, generates exciting and rigorous data that drive confident decisions, contributes critical thinking, technical expertise, and scientific insight to teamwork, and. The Gastrointestinal and Inflammation (GI2) Drug Discovery Unit at Takeda is building a new team of experienced, innovative, and collaborative researchers to deliver an industry-leading portfolio of drugs for various gastrointestinal, autoimmune, and inflammatory diseases with high unmet medical needs.
Takeda
Boston, MA
The Bioanalytical and Biomarker Sciences and Technologies (BST) department at Takeda is seeking a strong scientific leader to join the group as a biomarker development or bioanalytical expert with experience in one or more technologies including immunoassay, cell-based assays, flow cytometry, LCMS, and/or genomics, to support the clinical development of novel therapeutics across a range of disease areas including oncology, immunology, gastrointestinal, neuroscience. Success in this role will be evaluated by the ability to build effective partnerships with relevant colleagues within BST and across Takeda, and align and deliver on BST deliverables with a focus on high-quality and timely delivery of biomarker and bioanalytical data for ongoing clinical trials.
Takeda
Cambridge, MA
Screen for miRNA, mRNA, and Protein biomarkers using high-plex multi-omics spatial transcriptomics platforms to identify disease-specific or common autoimmune biomarkers. After the internship, the intern is expected to be proficient in the high-plex multi-omic assay workflow, understand hypothesis-driven experiment design, and be able to share findings at Takeda's inter departmental meetings.