NewProgram Manager, Principal - Secret DCS CorporationProgram Manager, Principal - SecretBedford, MA$123,639–$199,000 / yearIn this Advisory and Assistance Services (A&AS) role, you will provide expert-level support to Department of Defense (DoD) programs by assisting government leadership with decision-making, planning, and execution throughout the acquisition lifecycle. DCS has an exciting opportunity for a Program Manager SME (Principal) supporting the Air Force Life Cycle Management Center/PEO Electronic Systems Directorate (AFLCMC/HB) within the HBU Force Protection Division at Hanscom AFB.
NewPrincipal Mechanical Engineer Viken DetectionPrincipal Mechanical EngineerBurlington, MAThe Principal Mechanical Engineer partners closely with Engineering, Physics, Program Management, and Operations to deliver high-performance, manufacturable, reliable, and cost-effective solutions from concept through sustaining engineering. Job Description Description: Viken Detection is seeking a highly experienced Principal Mechanical Engineer to provide technical leadership and architectural ownership across our advanced detection and imaging systems.
NewPrincipal Design Quality Engineer I Nova BiomedicalPrincipal Design Quality Engineer IWaltham, MA$120,000–$160,000 / yearNova Biomedical is proud to be a global leader in osmolality testing and biotechnology and in vitro diagnostic (IVD) instrumentation, dedicated to advancing patient care and scientific discovery with a legacy that continues to shape the future of life sciences. With headquarters in Norwood and Waltham, Massachusetts, and a global team of nearly 2,000 employees, we’re building a collaborative, empowered culture grounded in shared values: Customer Centricity, Ingenuity, Ownership & Accountability, Collaboration, and Integrity .
NewPrincipal Mechanical Design Engineer RISE RoboticsPrincipal Mechanical Design EngineerSomerville, MAJob Description Founded in 2011 by graduates of MIT and RISD (Rhode Island School of Design), and backed by Engine Ventures, Techstars, Fortistar and Gates Corporation, RISE Robotics is leading the way to Zero Emission heavy machinery by providing the world’s most efficient and productive alternative to hydraulics. Proven technical aptitude and experience with electro-mechanical design and related manufacturing processes that might include: complex mechanical assemblies; rotating machinery; tolerance studies; design for assembly / manufacturing; EE and ME component and material selection; FMEA; design for life.
NewElectrical Engineer (Senior/Staff/Principal) NanopathElectrical Engineer (Senior/Staff/Principal)Cambridge, MAWe aim to replace lengthy molecular testing workflows by bringing rapid, high-quality diagnostics closer to the patient. At Nanopath we are dedicated to building a diverse and inclusive workplace, so if you're excited about this role but your past experience doesn't align perfectly with every point in the job description, we encourage you to apply anyways.
NewPrincipal Pulsed Power Engineer Diversified Technologies, Inc.Principal Pulsed Power EngineerBedford, MA$160,000–$200,000 / yearDTI’s work involves the design, construction, installation and testing of specialized, high-power electrical equipment for industrial and government applications. DTI seeks a Principal Pulsed Power Engineer for various projects to join its fast-growing, high technology business.
NewPrincipal Data Strategist, Real World Evidence Gateway RecruitingPrincipal Data Strategist, Real World EvidenceBoston, MAThis incumbent will be operating with a high degree of autonomy, this individual will shape fit-for-purpose RWD strategies, evaluate and operationalize external data assets, and lead advanced analytics initiatives using EHRs, claims, registries, and linked healthcare data. The Principal Data Strategist, Real World Evidence (RWE) will lead enterprise real-world data (RWD) strategy and advanced analytics initiatives that support scalable, regulatory-aligned evidence generation.
NewPrincipal Electrical Engineer Berkshire GreyPrincipal Electrical EngineerBedford, MAThe ideal candidate will excel at concepting, designing, prototyping, and testing new designs, plus launching products into production and supporting deployed systems. Join us at Berkshire Grey to deliver best-in-class robotic automation solutions that solve real customer problems and deliver immediate value.
Cyber Defense Principal Engineer Spyglass Partners, LLCCyber Defense Principal EngineerHybrid/Onsite, MASpyglass Partners LLC has over 20 years of experience as a nationwide staffing firm and is your ideal source for all your project-based temporary and direct-hire staffing needs. Spyglass Partners excels in placing contract and direct-hire resources across all aspects of IT, Accounting & Finance, Sales, and Executive roles.
Senior/Principal Scientist, Analytical Cell Line Engineering and Bioassay Development 3316 Takeda Development Center AmericasSenior/Principal Scientist, Analytical Cell Line Engineering and Bioassay DevelopmentLexington, Massachusetts$154,400–$242,550 / yearHow you will contribute: Lead the design, generation, characterization, and lifecycle management of stable mammalian analytical cell lines expressing targets of interest, receptor systems, or reporter constructs to support potency and functional bioassays. Operating at the interface between Discovery, Global Biologics, Analytical Development, and late-stage potency teams, this role translates product mechanism of action into scientifically sound, phase-appropriate cell line and assay strategies.
Principal C# Engineer / Technical Lead Integrated Computer SolutionsPrincipal C# Engineer / Technical LeadWaltham, MassachusettsICS blends the art of visual design and agile engineering to help our clients develop their products into devices that delight in a wide range of technologies. As a Principal Engineer / Technical Lead, you will be responsible for the design, development, and testing of software products in the Microsoft stack in the MedTech and industrial space.
Principal, Talent Management Partner's CapitalPrincipal, Talent ManagementBoston, MassachusettsClients include Syracuse University, Sesame Workshop, INSEAD Business School, New York’s Metropolitan Opera, San Francisco Symphony, Eton College, Colorado College, several Oxford and Cambridge University colleges, family offices around the world, and senior executives from leading global investment firms. Manage the mentorship program across business lines, including reviewing and revising mentor pairings, supporting education and development for all North America mentors, and collaborating with cross-regional mentors to ensure familiarity with North America programming.
Investment Principal, Public Markets Partner's CapitalInvestment Principal, Public MarketsBoston, MassachusettsClients include Syracuse University, Sesame Workshop, INSEAD Business School, New York’s Metropolitan Opera, San Francisco Symphony, Eton College, Colorado College, several Oxford and Cambridge University Colleges, several family offices around the world, and senior executives from leading global investment firms. With $75B+ in assets under management, the firm constructs customized investment portfolios for its clients tapping into its deep network of partnerships with what we consider exceptional asset managers across all major asset classes.
Client Service Principal, Taxable Partner's CapitalClient Service Principal, TaxableBoston, MassachusettsProactively identify and mitigate potential risks related to client accounts, working internally to identify, assess, and mitigate risks associated with client accounts and operational processes. Hands-on experience servicing US taxable clients (HNW families and family offices), including multi-entity household structures, tax-aware investment operations, and coordination with external CPAs and trust & estate counsel.
Principal Software Engineer - AI New BalancePrincipal Software Engineer - AIBrighton, MA$120,000–$150,000 / yearA core focus of this role is designing and building enterprise-grade AI assistants and automations using RAG and agentic AI techniques -software agents that can plan, coordinate tools, interact with systems, and execute multi-step workflows with appropriate guardrails. This team is responsible for researching and delivering AI based solutions across the company to improve internal workflows, decision-making, and operational efficiency across a wide range of business functions, including operations, supply chain, finance, product, and corporate services.
Principal Application Scientist Revvity, Inc.Principal Application ScientistHopkinton, MA$120,000–$155,000 / yearWorking with key commercial entities, you will craft automation methods & workflows that will be disseminated globally, allowing Revvity specialist to support internal sales specialists and customers with novel and well annotated automation methods, allowing Revvity to continue to lead the field. The individual is expected to support the global Revvity automation business by expanding instrument capabilities, working as necessary with technical support to troubleshoot complex customer issues, and providing training and marketing material for new application capabilities that will be used to support the sales of automation instruments globally.
Principal Engineer, Core Infrastructure KlaviyoPrincipal Engineer, Core InfrastructureBoston, MA$244,000–$366,000 / yearIn addition to base salary, our total compensation package may include participation in the company's annual cash bonus plan, variable compensation (OTE) for sales and customer success roles, equity, sign-on payments, and a comprehensive range of health, welfare, and wellbeing benefits based on eligibility. AI‑enabled platform: Approved AI tooling is integrated into IDE/CI/CD with repo policies and auditability; 70% MAU among eligible engineers; MTTR down 20-30% via AI‑assisted triage; flaky‑test rate decreases through targeted, AI‑suggested fixes.
Principal Engineer - Security Products, Security Visibility DigitalOceanPrincipal Engineer - Security Products, Security VisibilityBoston, MARemote$235,200–$294,000 / yearEvolve the Audit Logging Platform: Lead the redesign of DigitalOcean's audit log infrastructure to support immutable, tamper-evident, compliance-grade event records with fine-grained retention controls, cross-account federation, and real-time streaming access for customers and internal security teams. Core Experience: You possess over 10 years of software engineering expertise, including 4+ years dedicated to audit logging, security telemetry, SIEM integration, or managing high-throughput data pipelines within cloud or IaaS ecosystems.
Principal Scientist, Antibody Discovery and Engineering ModernaTXPrincipal Scientist, Antibody Discovery and EngineeringCambridge, MassachusettsThis individual will operate with a high degree of independence, scientific judgment, and cross-functional influence while partnering with antigen design, structural and computational biology, Immuno-oncology and Autoimmune Therapeutics research leadership, project teams, and external CRO partners. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Principal Software Engineer Boston Human Capital PartnersPrincipal Software EngineerBoston, MassachusettsRemoteThis role centers on building high-performance distributed systems, powering data-intensive services, and enabling seamless, secure integrations across modern IT and security ecosystems. only) and best suited for engineers who excel in fast-moving startup environments where autonomy, rapid iteration, and strong technical judgment are essential.