NewPrincipal Scientist - Drug Discovery (Diabetes) Novo Nordisk ASPrincipal Scientist - Drug Discovery (Diabetes)Waltham, MA$185,000–$230,000 / yearInternal relationships include working closely with technical staff & other members of the scientific leadership team; regular collaborations with members of other research departments at Novo Nordisk; & frequent interaction with project managers & other colleagues across global R&D. With your translational mindset and background within Diabetes and metabolic disease, you will be responsible for the establishment and utilization of relevant molecular approaches, cellular assays, and read-outs in order to investigate the mode-of-action of novel drug candidates and to progress our research projects.
Preschool Intensive Special Education Instructional Assistants (4) (SY 2026-2027) Needham Public SchoolsPreschool Intensive Special Education Instructional Assistants (4) (SY 2026-2027)Needham, MA$24.94–$29.27 / hourJob Description: Under the direct supervision of the Special Education Teacher, Board Certified Behavior Analyst (BCBA), and Special Education Coordinator/Director, the Intensive Special Education Instructinoal Assistant provides specialized instruction and support for students with complex learning profiles and/or behavioral challenges enrolled in the Intensive Learning Center/Post Graduate Program, utilizing the strategies of applied behavior analysis. Depending on grade level and the individual needs of students, Intensive Special Education Instructional Assistants may be responsible for the following: Provide 1:1 or small group specialized instruction for students with significant special needs utilizing the strategies of applied behavior analysis which may take place in an inclusion setting.
Preschool Intensive Special Education Instructional Assistants (SY 2026-2027) Needham Public SchoolsPreschool Intensive Special Education Instructional Assistants (SY 2026-2027)Needham, MAJob Description: Under the direct supervision of the Special Education Teacher, Board Certified Behavior Analyst (BCBA), and Special Education Coordinator/Director, the Intensive Special Education Instructinoal Assistant provides specialized instruction and support for students with complex learning profiles and/or behavioral challenges enrolled in the Intensive Learning Center/Post Graduate Program, utilizing the strategies of applied behavior analysis. Depending on grade level and the individual needs of students, Intensive Special Education Instructional Assistants may be responsible for the following: Provide 1:1 or small group specialized instruction for students with significant special needs utilizing the strategies of applied behavior analysis which may take place in an inclusion setting.
Preschool Special Education Instructional Assistant .8 FTE (SY 26-27) Needham Public SchoolsPreschool Special Education Instructional Assistant .8 FTE (SY 26-27)Needham, MA$23.94–$27.97 / hourRegularly required to sit (including sitting on the floor or other hard surface), stand, walk, kneel, talk, hear, operate a computer, handheld learning devices and other office equipment, reach with hands and arms, work indoors or outdoors, and must occasionally lift and/or move up to 10 pounds. Job Description: Under the direct supervision of the Special Education Teacher, Classroom Teacher, and Special Education Coordinator/Director, the Instructional Assistant will work closely with students in the classroom to meet instructional and social-emotional goals and objectives as well as to maintain appropriate student behavior.
Aide/ESP - Algonquin Regional High School - Education Support Professional The Public Schools of Northborough And SouthboroughAide/ESP - Algonquin Regional High School - Education Support ProfessionalSouthborough, MAParticipate in a weekly meeting with the student support services team that includes data review, academic, social, and behavioral programming updates, and sharing of concerns. Skills, Knowledge and Ability: Skilled in implementing instructional and behavioral methods and procedures appropriate for the situation when learning or teaching new things.
Program Manager, Principal - Secret DCS CorporationProgram Manager, Principal - SecretBedford, MA$123,639–$200,000 / yearIn this Advisory and Assistance Services (A&AS) role, you will provide expert-level support to Department of Defense (DoD) programs by assisting government leadership with decision-making, planning, and execution throughout the acquisition lifecycle. DCS has an exciting opportunity for a Program Manager SME (Principal) supporting the Air Force Life Cycle Management Center/PEO Electronic Systems Directorate (AFLCMC/HB) within the HBU Force Protection Division at Hanscom AFB.
Interim Elementary Principal Stoughton Public SchoolsInterim Elementary PrincipalStoughton, MA$120,000–$145,000 / yearGibbons Elementary School has an opening for an Interim Principal for the 2026-2027 school year. Anticipated Salary Range: $120,000-145,000.
Director (Principal Scientist), Clinical Research, Respiratory Merck & Co IncDirector (Principal Scientist), Clinical Research, RespiratoryBoston, MA$255,800–$402,700 / yearThe Clinical Director is responsible for maintaining a strong scientific fund of knowledge by: Maintaining awareness of scientific developments within his/her area of expertise, in terms of new scientific findings, research methodologies. The Clinical Director (Principal Scientist) has primary responsibility for planning and directing clinical research activities involving new or marketed medicines in the Cardiovascular and Respiratory therapeutic area.
Principal Software Engineer Xometry IncPrincipal Software EngineerWaltham, MA$200,000–$225,000 / yearXometry's digital marketplace gives manufacturers the critical resources they need to grow their business while also making it easy for buyers at Fortune 1000 companies to tap into global manufacturing capacity. Operational Excellence: You will own the reliability and security of the integration microservices, ensuring that "click-to-buy" functionality is bulletproof and that monitoring/alerting covers the unique lifecycle of enterprise PLM transactions.
Principal Scientist, In Vivo Pharmacology, Oncology Merck & Co IncPrincipal Scientist, In Vivo Pharmacology, OncologyBoston, MA$176,200–$277,300 / yearRequired Skills: Cancer Research, Drug Discovery Process, Immunoassays, Immunohistochemistry (IHC), In Vivo Models, Leading Project Teams, Mass Spectrometry Imaging, Molecular Biology Techniques, Mouse Models, Multiplex Assays, Oncology, Pharmacokinetics, Pharmacology, Tumor Biology. The role will involve building alliances with Discovery Oncology teams at the Boston and South San Francisco sites, championing new technologies (e.g., spatial biology using novel multi-plex immunohistochemistry capabilities), and interfacing with our global pharmacology network.
Principal Scientist, Early Clinical Development, Respiratory Therapeutic Area Merck & Co IncPrincipal Scientist, Early Clinical Development, Respiratory Therapeutic AreaBoston, MA$260,300–$409,700 / yearPrimary responsibilities for the Principal Scientist include the following: Working with basic science teams on specific diseases and therapeutic areas, providing clinical expertise for identification and validation of novel targets, including the design of preclinical and clinical experiments to validate targets and/or pathways, and leveraging this work for development of novel therapeutics. Required Skills: Allergy and Immunology, Asthma, Biomedical Research, Chronic Obstructive Pulmonary Disease (COPD), Clinical Development, Clinical Medicine, Clinical Research, Clinical Trial Planning, Cross-Functional Teamwork, Pulmonary Disease Research, Pulmonary Disorders, Pulmonology, Translational Research.
Principal Front-Office Engineer, Investments Strategy & Capital Management Liberty Mutual Holding Company IncPrincipal Front-Office Engineer, Investments Strategy & Capital ManagementBoston, MAAs a Principal Front-Office Engineer, you will serve as the technical lead embedded within the Investment Strategy & Capital Management team, driving design and implementation of small-scale applications and proof of concepts that will improve investment analysis, develop AI-enabled workflows, and enhance reporting systems & processes. You will partner closely with analysts and investment teams to enhance their day-to-day use of AI, helping them build artifacts in a more technically sound manner and building robust systems and tools that scale those prototypes into production-ready applications.
NewProgram Manager, Principal - TS/SCI DCS CorpProgram Manager, Principal - TS/SCIBedford, MA$123,639–$210,000 / yearThe DAF BATTLE NETWORK is the integrated system-of-systems fusing sensors, effectors, and sustainment grids to build situational awareness, make operational decisions, and direct the force to create needed lethal and nonlethal effects in support of the Joint Force Commander’s scheme of maneuver. The DAF PEO C3BM has the responsibility of technically and programmatically integrating the DAF’s larger system-of-systems architecture needed to deliver an integrated Command and Control (C2) core function for the DAF, Joint, and Coalition forces, by teaming with all other DAF PEOs, as needed.
NewPrincipal Aerospace Engineer Enigma AerospacePrincipal Aerospace EngineerBurlington, MABy combining a novel fixed-wing aircraft design with advanced mission and flight autonomy software, Enigma enables runway-independent resupply in vast, contested theaters and dramatically reduces the cost of commercial cargo delivery. In this role, you will have primary responsibility for the aircraft design, systems architecture, significantly contribute to the development and integration efforts, establish and manage vendor relationships, and help grow a high-performing technical team.
Principal Specialist Sales Engineer, Zero Trust Branch - Majors, East Zscaler IncPrincipal Specialist Sales Engineer, Zero Trust Branch - Majors, EastBoston, MARemote$175,875–$251,250 / yearThe Speciality Sales team is a global group of professionals who are passionate about delighting our customers, nurturing trusted partnerships, and sharing their expertise to drive a secure, cloud-enabled digital future and further cement our position as the world leader in cloud security. Sales, Customer Success, Sales Enablement, Solution Architects, Business Development, Transformation, and Technology Partnerships all work together to demonstrate the power and agility of Zscaler cloud transformation to the world, and we are looking for your expertise to elevate our Exposure Management team.
TEMP Principal DevOps Engineer Doble Engineering CompanyTEMP Principal DevOps EngineerMarlborough, MAPHYSICAL REQUIREMENTS: While performing the duties of this job the employee is often required to stand, sit, use computers, read, write, type, use copy machines, file paperwork, use telephones, and utilize written and oral communication to interact with clients, co-workers, and customers. A function may be essential for any of several reasons, including: the job exists to perform that function, the employee holding the job was hired for his/her expertise in performing the function, or only a limited number of employees are available to perform that function.
Principal DevOps Engineer Evolv Technologies IncPrincipal DevOps EngineerWaltham, MA$137,000–$220,000 / yearIn accordance with state and local pay transparency laws-including those in California, Colorado, Massachusetts, New York, New Jersey, and others-we disclose salary ranges in all job postings and provide additional information upon request. In this role, you will partner closely with Platform, Security, Compliance, and Engineering teams to enable reliable, audit-ready cloud environments while balancing velocity, security, and operational excellence.
Principal Motion Planning Engineer Pickle Robot CoPrincipal Motion Planning EngineerMA$150,000–$170,000 / yearSkills and Experience: 8+ years building robotics software, with a sustained record of designing and shipping complex systems as a senior individual contributor; deep graduate robotics/controls research experience counts toward this. Take on the hardest algorithmic problems in planning and control - sample-based planning (e.g., RRT), path and trajectory optimization, numerical/nonlinear optimization, and contact-aware control - and turn research prototypes into production systems.
Principal Specialist Sales Engineer, Data Security - Majors, East Zscaler IncPrincipal Specialist Sales Engineer, Data Security - Majors, EastBoston, MA$175,875–$251,250 / yearZscaler is committed to providing reasonable support (called accommodations or adjustments) in our recruiting processes for candidates who are differently abled, have long term conditions, mental health conditions or sincerely held religious beliefs, or who are neurodivergent or require pregnancy-related support. The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all US locations and could be higher or lower based on a multitude of factors, including job-related skills, experience, and relevant education or training.
Principal Finance Manager Onto Innovation IncPrincipal Finance ManagerWilmington, MAOnto Innovation is a leader in process control, combining global scale with an expanded portfolio of leading-edge technologies that include: 3D metrology spanning the chip from nanometer-scale transistors to micron-level die-interconnects; macro defect inspection of wafers and packages; metal interconnect composition; factory analytics; and lithography for advanced semiconductor packaging. In this role, you will support multiple business and project teams with competing priorities while providing clear financial insight, disciplined budget management, and actionable analysis to leadership.