244 Results for

Principal Jobs in Brookline, MA

Jobs

New!

Bedford, MA2 days ago

$123,639–$145,000 Per Year

Command, Control, Communications, and Battle Management (C3BM) has been tasked with delivering an integrated Department of the Air Force (DAF) Battle Network providing resilient decision advantage and enabling the USAF, USSF, Joint, and Coalition Force to win against the pacing challenge. C3BM’s main efforts are Architecture and Systems Engineering (ASE), Operational Response Team (ORT), and multiple mission integration teams such as Air, Maritime and multiple acquisitions consisting of both the Advanced Battle Management System (ABMS) and Space.

Billerica, MA11 days ago

Drive product development from concept through manufacturing, including: System architecture and conceptualization. Ability to innovate and apply new technologies or existing methods to solve complex design challenges.

Weymouth, MA19 days ago

$120,000–$150,000 Per Year
Full-time
Employee

Write and analyze test plans, execute tests and evaluate test results to demonstrate the design meets specifications with high quality. Develop assembly processes and instructions using lean principles to safely reduce waste, increase efficiency, and improve product quality.

Quincy, MA11 days ago

$165,500–$234,700

Saab Inc., Autonomous and Undersea Systems division is seeking an innovative and experienced Principal Mechanical Engineer to guide others on technical teams in capturing, understanding, and implementing product design requirements for autonomous Unmanned Surface/Underwater Vehicles (aUSVs/aUUVs, AUVs) and Remotely Operated Vehicles (ROVs). Demonstrated performance and expertise in the elements of mechanical design, such as analysis and implementation of requirements, developing design concepts, evaluating designs, technical and design reviews.

New!

Boston, MAToday

$160,739–$200,924 Per Year

Minimum qualifications: Master’s degree in Operations Research, Data Science, Statistics, Applied Mathematics, Engineering, Computer Science or related field; 5 years in quantitative pricing/financial analysis. Demonstrated ability to frame complex problems, select appropriate research/analytical methods, implement solutions, and present findings effectively.

New!

Hopkinton, MAToday

Join us to do the best work of your career and make a profound social impact as a Software Principal Engineer on our Software Engineering Team in Hopkinton, MA.We are seeking a Principal Engineer to provide technical leadership across modern software delivery platforms, with a strong focus on DevOps CI/CD pipelines, end-to-end security scanning, and agentic AI systems. The ideal candidate combines deep systems expertise with a forward-looking mindset, driving automation, resilience, and secure-by-design practices while exploring how autonomous and agentic AI can enhance developer productivity and operational excellence.

Andover, MA11 days ago

Translate engineering design requirements into formal manufacturing process documentation including raw material definition, fixturing/tooling development, CNC programming, inspection planning, finishing requirements, and assembly instructions. Qualifications You Must Have: * Typically requires a Bachelor's Degree in Manufacturing Engineering, Mechanical Engineering, Industrial Engineering, Electrical Engineering, or Aerospace Engineering.

Boston, MA9 days ago

Drive design and implementation of small-scale applications and proof of concepts to improve risk analysis, develop AI-enabled workflows, and enhance reporting systems and processes. Work closely with risk analysts and investment teams to build robust systems and tools that power risk infrastructure, analytics, and decision-ready reporting.

Boston, MA9 days ago

Lancaster, MA30+ days ago

Must assist in enforcing the school code of conduct, testing and assessment programs, preparation of student and class schedules, assist all custodial, cafeteria, and other support services, assist in all curriculum matters. Assist parents through prompt communication and support for the purpose of impacting and improving students' academic performance.

Boston, MA30+ days ago

Assists the administration in implementing all policies and rules governing student life and conduct, and for the classroom, develops reasonable rules of classroom behavior and procedure, and maintains order in the classroom in a fair and just manner. Employs a variety of instructional techniques and instructional media, consistent with the physical limitations of the location provided and the needs and capabilities of the individuals or student groups involved.

Boston, MA30+ days ago

General Description: Under the general supervision, serves as secretary to the principal or headmaster of a school; performs complex clerical work requiring exercise of independent judgment. Email: hiringprocess@bostonpublicschools.org.

Natick, Massachusetts30+ days ago

$200,000–$300,000 Per Year

Andover, MA30+ days ago

$112,700–$187,800 Per Year

Team leader responsible for the safety and oversight of Technical Programs laboratory-based and at-scale work, including small-scale cleaning validation program requirements, mixing qualification, and solution chemical stability and expiry. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.

Boston, MA30+ days ago

Full-time

ODAIA's SaaS platform transforms complex data into predictive, personalized insights, enabling commercial leaders to understand their customers, anticipate prescribing behaviors, and make the informed, strategic decisions that bring therapies to patients faster. A proven track record of building successful partnerships, advising commercial pharma executives, leading high-stakes conversations and influencing multi-million dollar commercial investment decisions through data-driven storytelling.

Boston, MA30+ days ago

We focus all of our energy on discovering and solving customer and business problems, designing financially strong and defensible business models, activating growth engines, hiring world-class founding teams, and helping them thrive (and none of our energy on big-company b.s.). Led by co-founders who have both built unicorn real estate tech companies from scratch, we're a tight team of engineers, product managers, designers, and operators with decades of experience building products, teams, and businesses from startup to scale.

BURLINGTON, MA30+ days ago

Remote

We are seeking a Principal Consultant – Aviation Noise to join our team in a remote or hybrid position in the U.S. In this senior role, you will serve as a recognized technical expert in aviation noise, leading large and complex projects, supervisingand mentoringstaff, shaping practice strategy, and expanding HMMH’s presence in the aviation noise field. Our Aviation Environmental & Sustainability Group supports over 200 airports worldwide with noise and air quality studies, sustainability plans, mitigation strategies, environmental documentation, and regulatory compliance.

Andover, MA13 days ago

Translate engineering design requirements into formal manufacturing process documentation including raw material definition, fixturing/tooling development, CNC programming, inspection planning, finishing requirements, and assembly instructions. Typically requires a Bachelors Degree in Manufacturing Engineering, Mechanical Engineering, Industrial Engineering, Electrical Engineering, or Aerospace Engineering.

Lancaster, MA30+ days ago

The job of Principal - Elementary was estabished for the purpose/s of providing support to the instructional process with specific responsibility for directing overall site operations, services and staff at an elementary school; providing information and serving as a resource to others; enforcing established policies and regulatory requirements; coordinating school activities and addressing issues, situations and/or problems that arise on campus or with enrolled students. Minimum requirements: Master's degree, or higher in job related area, two years of administrative experience as well as five (5) years as a teacher preferred.

Boston, MA26 days ago

$150,000–$180,000 Per Year
Full-time

Client Details The client is an innovative connected‑fitness company that blends advanced hardware, immersive digital content, and intuitive software to deliver a premium at‑home training experience, while fully owning and leading the entire electrical design function across its product portfolio. The position owns the entire electrical engineering function, working closely with mechanical, firmware, and software teams to deliver high‑quality, scalable consumer products.

New!

Waltham, MA3 days ago

$120,000–$160,000 Per Year

Nova Biomedical is proud to be a global leader in osmolality testing and biotechnology and in vitro diagnostic (IVD) instrumentation, dedicated to advancing patient care and scientific discovery with a legacy that continues to shape the future of life sciences. With headquarters in Norwood and Waltham, Massachusetts, and a global team of nearly 2,000 employees, we’re building a collaborative, empowered culture grounded in shared values: Customer Centricity, Ingenuity, Ownership & Accountability, Collaboration, and Integrity.

New!

Waltham, MA3 days ago

$155,000–$190,000 Per Year

Nova Biomedical is proud to be a global leader in osmolality testing and biotechnology and in vitro diagnostic (IVD) instrumentation, dedicated to advancing patient care and scientific discovery with a legacy that continues to shape the future of life sciences. Lead system-level analysis and risk mitigation strategies related to battery thermal behavior and heat dissipation, including charging scenarios, environmental extremes, and long-term reliability to ensure patient safety and regulatory compliance.

New!

Boston, MA1 day ago

$90–$95

Experience with DLP, Encryption, Tokenization & HSM-based Key ManagementNotePreferred Qualifications: Experience in financial services, telecom, or government sectors. Experience Needed: 15+ YearsKey Skills Required: 10+ years in Cybersecurity Architecture & Engineering.

Boston, MA25 days ago

$150,000–$180,000 Per Year

The client is an innovative connected‑fitness company that blends advanced hardware, immersive digital content, and intuitive software to deliver a premium at‑home training experience, while fully owning and leading the entire electrical design function across its product portfolio. The position owns the entire electrical engineering function, working closely with mechanical, firmware, and software teams to deliver high‑quality, scalable consumer products.

Waltham, MA13 days ago

We are looking for an experienced researcher to join our team as Principal Research Associate/Associate Scientist in the Molecular Assembly team, supporting our novel target identification and validation workflow in house. Excellent written and verbal communication skills, with the ability to document experiments in an organized and timely fashion and to present scientific data to coworkers.

Somerville, MA, MA30+ days ago

Full-time

Create conceptual techno-economic on-site energy solutions that appreciate and address the complex customer pain points of energy cost, sustainability, reliability, resilience, Capex constraints, and risk management (includes detailed data analysis, conceptual design, and modelling). The Principal Solutions Architect Engineer will also work with Schneider Electric (SE) Microgrid Competency Center (MGCC), Energy and Sustainability Services (ESS), and other SE business units as well as The Carlyle Group, various generation firms, and Engineer Procure Construct (EPC) firms.

Boston, MA30+ days ago

$164,800–$206,000 Per Year

This role is the linchpin connecting cutting-edge technology with transformative workforce solutions, directly shaping products that empower businesses to hire, pay, and manage global teams seamlessly. Strategically leverage AI to create novel software solutions that tackle complex global workforce management and compliance issues, utilizing the Partner ecosystem to showcase and validate platform capabilities.

Burlington, MA30+ days ago

The Principal Electrical Engineer is a senior technical leader responsible for developing Butterfly's industry leading ultrasound products from concept to commercial launch and production scale-up. As part of our team, your core responsibilities will be: Lead electrical architecture and design for medical devices across the full product lifecycle, from early feasibility and risk analysis through design transfer, manufacturing, and post-market support.

Burlington, MA30+ days ago

With our proprietary Ultrasound-on-Chip technology, we're democratizing healthcare by shifting ultrasound from the expensive, stationary systems of the past to the connected, mobile, and software-enabled platforms of today. Immediately reporting any suspected or actual security incidents, including phishing attempts, malware infections, or unauthorized access, following the established incident response procedure.

Waltham, MA25 days ago

Full-time

This individual, with some supervision, will independently drive synthesis, purification, formulation, and analytical characterization of modified oligonucleotides to support discovery and early development programs. In our fast-paced startup environment, this role requires strong technical skills, hands-on execution, problem-solving creativity, and a willingness to take ownership of processes and infrastructure as we scale.

Waltham, MA12 days ago

$137,000–$220,000

In accordance with state and local pay transparency laws—including those in California, Colorado, Massachusetts, New York, New Jersey, and others—we disclose salary ranges in all job postings and provide additional information upon request. In this role, you will partner closely with Platform, Security, Compliance, and Engineering teams to enable reliable, audit-ready cloud environments while balancing velocity, security, and operational excellence.

Cumberland, RI30+ days ago

$120

This hybrid role bridges traditional Microsoft Information Protection and compliance tools with modern AI-centric data security practices, including encryption for LLM pipelines, secure vector stores, and legacy data remediation. - Looking for experience with Snowflake, Microsoft Defender, DLP tools, Azure Purview and with a data engineering background that is operating in an oversight role or assisting a larger organization using those tools.

Woburn, MA21 days ago

$140,000–$230,000 Per Year

One or more of the following credentials: certified public accountant (CPA), certified valuation analyst (CVA), accredited in business valuation (ABV), chartered financial analyst (CFA), certified business appraiser (CBA), accredited senior appraiser (ASA), certified divorce financial analyst (CDFA) CPA, CVA, ABV, CBA, or ASA certification is required 10+ years' of recent experience in a related field, with a proven ability to lead and develop client relationships. Proactively identifies and communicates issues to clients, provides value added advice; is viewed as a qualitative and quantitative resource for partners and staff to resolve issues within practice segments and/or industry specialization(s).

Waltham, MA30+ days ago

$170,000–$200,000

This role is ideal for an engineer who thrives at the intersection of analog, highspeed digital, mixed signal, and system integration, and who enjoys solving ambiguous problems by turning constraints into clear, robust designs .   . As part of a small, highly collaborative engineering organization, you will work closely with other senior engineers to define system architectures, lead tradeoff analyses, and drive critical technical decisions.

Boston, MA30+ days ago

Remote

$119,000–$160,650 Per Year

We help extend the value of these assets, enabling our customers to embrace the potential of cloud and mobile computing, advanced analytics, and the innovations of tomorrow. + Demonstrated history as a consistent top performer selling software solutions to senior executives with quotas in excess of 3M, selling large transactions.

Boston, MA29 days ago

$200,000–$230,000 Per Year

Our team of nearly 475 experts partners with 27 of the top 30 biopharmaceutical companies, the fastest-growing mid-caps, and cutting-edge emerging biotechs, including some of the biggest and most innovative brands. We partner with our clients to turn science into value by helping them understand the potential of their molecules, shaping their strategic plans, and allowing their decision-making to be the biggest differentiating factor in the success of their products.

Boston, MA30+ days ago

By combining advanced technology with a global network of talented people, we make unusable data usable, driving real-world impact at scale. Consulting & Client Leadership: Track record of leading large, complex engagements and influencing senior stakeholders.

Somerville, Massachusetts30+ days ago

$133,000–$165,000 Per Year

Lead and manage regulatory submissions, including FDA Q-submission, US 510(k)s submissions, Premarket Approvals (PMA) submissions, supplements, and reports, including Regulatory Body interactions. Regulatory Affairs Principal is responsible for developing and executing regulatory strategies, ensuring compliance with global regulations and leading the process to obtain and maintain market approval for DeepHealth’s high risk products, including AI technologies.

Somerville, Massachusetts15 days ago

$150,000–$190,000 Per Year

This leadership role will focus on establishing DeepHealth as the category leader in enterprise imaging operations in its targets markets and driving business growth by: Defining and executing the Operations Suite portfolio strategy, including RIS, Patient Engagement, Referral Management, and associated workflow, automation, analytics, and AI solutions—guiding roadmap priorities, platform architecture, platform modernization alignment, and market positioning. The Principal Product Manager, Operations Suite defines the portfolio commercialization for DeepHealth’s Operations Suite portfolio—including RIS, Patient Engagement, and Referral Management while leading the AI portfolio and productization of AI-driven workflow, automation, and analytics capabilities across the platform.

Somerville, Massachusetts30+ days ago

$130,000–$160,000 Per Year

Somerville, Massachusetts27 days ago

$200,000–$230,000 Per Year

The role drives the design, governance, and continuous improvement of automated security controls across all CI/CD pipelines and developer workflows—ensuring security is built in from design through production while enabling delivery that is fast, measurable, and audit-ready at scale. Advanced security certifications strongly preferred (CISSP, CSSLP, AWS Security Specialty, or equivalent); thought leadership through published work, conference presentations, or open-source contributions is a strong differentiator.

Andover, MA13 days ago

Translate engineering design requirements into formal manufacturing process documentation including raw material definition, fixturing/tooling development, CNC programming, inspection planning, finishing requirements, and assembly instructions. Qualifications You Must Have: Typically requires a bachelor’s degree in manufacturing engineering, Mechanical Engineering, Industrial Engineering, Electrical Engineering, or Aerospace Engineering .

Boston, MA7 days ago

$82.14

As a Principal Front-Office Engineer, you will serve as the technical lead embedded within the Risk team, driving design and implementation of small-scale applications and proof of concepts that will improve risk analysis, develop AI-enabled workflows, and enhance reporting systems & processes. •Strong SQL skills required with a familiarity of financial data platforms (such as Bloomberg, FactSet, Aladdin, eFront, Moodys), financial databases, and data manipulation techniques preferred.

Burlington, MA30+ days ago

Powered by trillions of lines of code scans and a proprietary AI-generated remediation engine, the Veracode platform is trusted by organizations worldwide to build and maintain secure software from code creation to cloud deployment. This role is ideal for an experienced professional who thrives in designing and maintaining scalable, secure, and cost-efficient CI/CD pipelines, Kubernetes clusters, and cloud-based systems.

Burlington, MA30+ days ago

Powered by trillions of lines of code scans and a proprietary AI-generated remediation engine, the Veracode platform is trusted by organizations worldwide to build and maintain secure software from code creation to cloud deployment. Strong understanding of various machine learning algorithms, including supervised and unsupervised learning, reinforcement learning, and neural networks.

Waltham, MA30+ days ago

Full-time

Working knowledge of advanced consulting methodologies, tools, and techniques – with focus on: leveraging AI, LLMs, and life sciences real-world data, for purposes such as patient finding, HCP segmentation, and other applications of advanced analytics, optimization of omnichannel plans, marketing mix, performance analytics and reporting related activities. 10+ years as a top performer within a top-tier biopharmaceutical / pharmaceutical strategy consulting firm serving industry leading clients and/or relevant experience with advanced analytics, omnichannel measurement, marketing analytics, and/or technology-enabled solutions within pharma and biotech.

Boston, MA25 days ago

Remote

Full-time

We are a rapidly growing, Boston-based medical technology company using AI to help clinicians make more informed decisions on cardiovascular care - leading to better patient outcomes, improved quality of care, and reduced healthcare costs. Compensation will be influenced by a wide array of factors including but not limited to internal pay equity, job-related knowledge, skills, education, relevant experience, certifications, and geography as outlined in the job description.

Bedford / Hanscom AFB, Massachusetts19 days ago

$140,000–$150,000 Per Year

The Air Force Program Execution Office for PEO Electronic Systems (ES) has the collective Air Force Materiel Command (AFMC) mission responsibility to manage and execute the modernization, development, testing, production, fielding, and sustainment of the PEO Digital portfolio, which includes over 130 programs for the United States Air Force (USAF) and foreign allies. Astrion has an exciting opportunity for a PRINCIPAL LOGISTICS MANAGERproviding support to the Air Force Life Cycle Management Center (AFLCMC), PEO Electronic Systems (ES) located at HANSCOM AFB, MA.

Bedford / Hanscom AFB, Massachusetts30+ days ago

Bedford / Hanscom AFB, Massachusetts30 days ago

Astrion has an exciting opportunity for a Principal Data Links and Communications Engineerfor the EPASS Cyber and Networks Directorate (EPASS HN II) contract, supporting the Aerial Networks Division (AFLCMC/HNA) located at Hanscom AFB, MA. Support defining and documenting a set of Combat Net Radio (CNR) networking parameter configurations to provide the best balance between flexible implementation of capability and implementation impact on both existing and emerging weapon systems.

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Principal Jobs in Brookline, MA

Jobs

Software Engineer, PrincipalDCS Corporation

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Principal Manufacturing EngineerButler Aerospace and Defense

IT Principal Front-Office EngineerAxelon Services Corporation

Principal Front-Office EngineerAxelon Services Corporation

Assistant Principal (2026-2027 School Year)Rutherford County Schools

1/2 STEM Teacher & 1/2 Assistant Principal at Midway Middle (26-27 School Year)Roane County Schools

Guild - Principal Clerk School Secretary Grade 23 (SY25-26)Boston Public Schools

Principal Scientist (M.D. or D.O.)Exponent Inc.

Principal Cleaning Validation EngineerPfizer

Managing Principal, AI-Driven Commercial EffectivenessOdaia Intelligence Inc.

Principal Engineer - Stackpoint VenturesStackpoint Studio Inc

Principal Consultant - Aviation NoiseHARRIS MILLER MILLER & HANSON INC.

Principal Manufacturing Engineer, 4th ShiftApollo Professional Solutions

Pleasant Hill Elementary - PrincipalCumberland County School District

Principal Electrical Engineer- Boston, MA- HybridMichael Page International

Principal Design Quality Engineer INova Biomedical

Principal Systems Engineer - POC DevicesNova Biomedical

Principal Cybersecurity ArchitectTMS

Principal Electrical Engineer- Boston, MA- HybridMichael Page

Principal Research Associate/Associate Scientist, Molecular AssemblyTScan Therapeutics

Principal Solutions Architect Engineer, MicrogridAlphaStruxure EmployeeCo, LLC

Principal Partner Platform AdvocateG-P

Principal Engineer, Electrical EngineerButterfly Network

Principal Engineer, Physical ImplementationButterfly Network

Principal Research Associate - Oligonucleotide ChemistryAlloy Therapeutics

Principal DevOps EngineerEvolv Technologies Inc.

Data Security Principal ArchitectLancesoft

BAS Principal - Valuation, Financial Forensics, Litigation (VFL)LitmanGerson Associates

Principal Electrical EngineerEvolv Technologies Inc.

Principal Account ExecutiveRocket Software

Director / Associate Principal - Medical and Scientific Strategy ConsultingPrescient Healthcare Group

Client Principal - AI Consulting (Property & Casualty Insurance)CloudFactory

Sr Regulatory Affairs Principal AutonomousDeephealth

Principal Product Manager OpsDeephealth

Sr Regulatory Affair PrincipalDeephealth

Principal Cloud Dev Ops EngineDeephealth

Principal Manufacturing EngineerLancesoft

IT Principal Front-Office EngineerLancesoft

Principal DevOps EngineerVeracode

Principal Security Researcher - AIVeracode

Principal, AnalyticsTrinity Partners, LLC

Principal Platform EngineerElucid

Principal Logistics ManagerAstrion

Principal Software EngineerAstrion

Principal Data Links and Communications EngineerAstrion

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