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Principal Jobs in Littleton, MA

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Principal Network Engineer Lila Sciences

Cambridge, Massachusetts

$171,000–$230,534 / year

As Principal Network Engineer, you will be the senior technical owner of that network: building the in-house engineering capability to design, secure, and scale it, while increasing the value and effectiveness of our managed service provider relationships. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

4 days ago

Principal DevOps Engineer BitSight Technologies Inc

Boston, MA

Remote

$126,000–$180,000 / year

This range reflects the minimum and maximum target for new hire salaries for the position across all US locations, is based on a full-time work schedule, and is Bitsight's good faith estimate as of the date of this posting. Operate EKS clusters, including capacity planning, node and pod density, graceful shutdown, and access models that give developers the access they need.

6 days ago

Principal DevOps Architect MKS Inc

Andover, MA

$140,000–$185,000 / year

Preferred Skills: Experience integrating Source Code Management, CI/CD Pipelines, DevSecOps tooling, secure artifact management, software supply-chain controls, and AI-assisted development capabilities into enterprise engineering workflows. You will partner directly with engineering teams, IT, and Security to architect and modernize our DevOps ecosystem, simplify a diverse tool landscape, create reusable engineering solutions, and establish platforms that teams can rely on.

6 days ago

Principal Thermal Mechanical Engineer JETCOOL Technologies

Littleton, Massachusetts

$153,500–$211,000 / year

The Principal Mechanical Engineer will provide technical leadership, mentorship, and hands-on expertise in mechanical design, fluid dynamics, and heat transfer but also work closely with customers in communicating the art of the possible with JetCool technology and building a strong customer relationship on a technical level. Lead the initial design, analysis, and optimization of complex fluid systems from concept initial CAD to final detailed CAD and drawing for liquid cooling, including cold plates, pumps, fluids, tubing, and heat exchangers, for the latest computer processing chipsets.

17 days ago

Principal Gifts Officer WGBH Boston

Boston, MA

$110,630–$140,600 / year

The successful candidate will be a senior-level relationship builder with credibility in building a high-net worth pipeline for philanthropy They will have a proven record of identifying, qualifying and cultivating high-net-worth prospects, closing complex major and principal gifts, building lasting donor relationships, and partnering effectively with senior leaders, volunteers, and stakeholders to achieve ambitious fundraising goals. Through individual giving, major gifts, planned giving, institutional fundraising, corporate support, membership, and campaign fundraising, the department builds meaningful relationships with donors who share GBH's commitment to journalism, education, culture, and community engagement.

8 days ago

Principal Scientist, R&D Data, Data Science & Artificial Intelligence - Immunology Johnson & Johnson

Cambridge, MA

Remote

$117,000–$201,250 / year

All Job Posting Locations: Cambridge, Massachusetts, United States of America, Raritan, New Jersey, United States of America, San Diego, California, United States of America, Spring House, Pennsylvania, United States of America, Titusville, New Jersey, United States of America. To successfully meet these objectives, this individual will work closely with clinical project teams and functional partners across Translational Science, Translational Medicine, Discovery, Late Development, Market Access, Medical Affairs, Data Platforms, Insights & Analytics, and other relevant functions.

6 days ago

Underwriting Principal Fifth Third Bank

Boston, MA

$96,500–$207,500 / year

Responsible for identifying, assessing and communicating credit risks; performing detailed due diligence and financial analysis; and supporting sound underwriting decisions within established policies and risk appetite, with escalation of complex, sensitive or policy-exception transactions as required. The base salary for this position is reflective of the range of salary levels for all roles within this pay grade across the U.S. Individual salaries within this range will vary based on factors such as role, relevant skillset, relevant experience, education and geographic location.

5 days ago

Associate Principal Scientist, Clinical Research Merck & Co Inc

Boston, MA

$142,400–$224,100 / year

Experience developing, implementing, and managing immunology clinical programs and trials in healthy participants and/or patients to ensure efficient, timely execution against milestones under accelerated timelines; experience with immunology early patient trials (eg, Phase 1b patient trials in rheumatology, dermatology, and/or gastroenterology) preferred. Brief Description of Position: Translational Medicine (TMed) drives early clinical development of novel therapeutics by partnering with Discovery Sciences and Late-Stage Clinical Research to translate scientific discoveries into human proof-of-concept and advance the most promising candidates through the pipeline to patients.

9 days ago

Principal Seller McKinstry Co.

Boston, MA

$153,400–$229,400 / year

The ideal candidate is a high-energy, results-driven sales executive with a proven track record of closing large-scale DER deals, strong industry relationships, and the ability to strategically position McKinstry's solutions in a highly competitive landscape. This role is responsible for sourcing, structuring, and closing high-value DER projects, driving revenue growth, and expanding McKinstry's market share as a designer, builder and operator of DER projects across the eastern US.

6 days ago

VP, Principal Resilience Engineer Chubb Ltd

Boston, MA

$158,550–$229,950 / year

Reporting to the Executive Vice President, Global Resilience and Risk Consulting, and working hand-in-hand with the Vice President, Community Resilience, the Principal Resilience Engineer will work across Chubb's risk consulting, underwriting, catastrophe modeling, claims, and analytics teams, as well as with external stakeholders, including property owners, developers, community associations, local governments, and utilities. The Principal Resilience Engineer will help communities understand what to do, help partners implement effective solutions, and help Chubb recognize meaningful risk reduction - supporting safer properties, stronger communities, and the responsible expansion of insurance in catastrophe-exposed markets.

7 days ago

Principal Innovation Developer - Cloud & AI Hewlett Packard Enterprise Company

Andover, MA

Full time

As an Innovation Engineer in the Hybrid Cloud CTO organization, you will play a senior individual contributor role responsible for driving complex, high-impact incubation projects across AI, cloud-native architectures, and emerging software technologies. Working alongside technical leads and cross-functional partners, you will design, implement, and validate advanced solutions that accelerate HPE's transformation and deliver innovative capabilities to internal teams and external customers.

9 days ago

Intelligence Center X Principal - Americas Mendix Technology BV

Boston, MA

$197,300–$394,600 / year

You lead the ideation and creation of our most strategic customer engagements - modelling complex domains as enterprise ontologies, designing agents and machine learning that reason over them and act on them, and delivering agentic applications that compel customers to invest in Intelligence Center X with Siemens. Engage executives and strategic partners - build and defend the business case with senior customer stakeholders, mobilize Siemens leadership, and lead strategic partnerships with GSIs, ISVs and hyperscalers.

8 days ago

Principal Audio DSP/ML Engineer- Audio Technology Bose Corporation, U.S.A

Framingham, California

$216,000–$297,000 / year

Design and develop audio signal processing and machine learning algorithms for speech and audio applications such as noise suppression, echo cancellation, beamforming, spatial audio, and audio enhancement. In this role, you will combine signal processing, machine learning, and systems engineering to deliver high-quality audio solutions for real-world consumer devices.

10 days ago

Principal Engineering Program Manager Hewlett Packard Enterprise Co

Andover, MA

$147,000–$279,000 / year

Communicates program progress, escalations, and issue analysis to product stakeholders; collaborates with management and internal manufacturing and development partners to recommend and implement changes to products, processes, or business practices to resolve escalated issues, produce solutions, and ensure adherence to budgets and established roadmaps and schedules; requires 3+ years presenting status, risks, and trade-offs to senior management. Manages activities of supporting project teams and internal development partners; ensures progress against established plans and uses analysis of business and execution data to alter or update schedules and resource allocations to meet product requirements and development schedules; requires 4+ years experience driving recovery plans for slipping milestones.

8 days ago

Principal Game AI Engineer Take-Two Interactive Software Inc

massachusetts, MA

$180,000–$210,000 / year

Subject to those same considerations, the total compensation package for employees in regular roles may also include other elements, including a bonus and/or equity awards, in addition to a full range of medical, financial, and/or other benefits, provided that temporary or intern roles will not be eligible for many of these payments or benefits. Who We Are: Ghost Story Games is a self-publishing game development studio founded by Ken Levine (Creative Director of System Shock 2, Bioshock, and Bioshock Infinite) and former Irrational Games developers.

9 days ago

Principal Legal Counsel SS&C Technologies Holdings Inc

Boston, MA

$160,000–$215,000 / year

More than 23,000 financial services and healthcare organizations, from the world's largest companies to small and mid-market firms, rely on SS&C for expertise, scale, and technology. Prepare and oversee production of various mutual fund, ETF and closed-end fund regulatory filings with the U.S. Securities and Exchange Commission, including registration statements on Form N-1A and Form N-2.

8 days ago

Associate Principal- Corporate Strategy Advisory Trinity Life Sciences

Waltham, Massachusetts

$170,000–$234,000 / year

Trinity’s salary bands account for a wide range of factors that are considered in making compensation decisions including but not limited to skill sets and market demand for skills; level of experience and training; specific qualifications, performance, time in role/company, geographic location, and other business and organizational needs. Associate Principals have unique • opportunities to manage daily client interactions with full oversight over project teams – client management, project management, employee management, budget and financial management, and more.

10 days ago

Test Architect Principal Cigna

Newton, MA

$151,600–$252,600 / year

Experience with test management and traceability tooling such as Jira with Xray or Zephyr, qTest, or TestRail, and with embedding quality and security gates in CI/CD platforms such as Jenkins, GitHub Actions, GitLab CI, or Harness, alongside scanning tools such as SonarQube, Snyk, or Checkmarx. Set direction for the PBS Test Lead on testing across the existing estate, confirming that regression of current systems, integration across both estates, and client-wave testing produce evidence that holds at the readiness gate.

8 days ago

Principal Electrical Engineer Re:Build Manufacturing

Wilmington, MA

$165,000–$250,000 / year

An experienced engineering leader with a broad range of electrical engineering disciplines, including analog and digital circuit design, power electronics, PCB design, sensors, instrumentation, embedded electronics, and electromechanical systems. We operate an advanced, end-to-end manufacturing platform that partners with industrial companies and innovators to take products from first concept to full-scale production in critical verticals including aerospace and defense, electrification, medical, energy and environment, and robotics and automation.

14 days ago

Principal Product Designer VIA

Somerville, Massachusetts

Remote

$160,000–$190,000 / year

Own end-to-end UX/UI design across VIA's product suite, including AI-native platforms, agentic workflow interfaces, multiplayer and collaborative data environments, and permission-controlled data sharing experiences. Agentic and collaborative workflow experience: You've navigated UX problems where multiple users or multiple agents interact with shared state, and you know how to make those flows feel clear, not chaotic.

9 days ago

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Principal Jobs in Littleton, MA

Principal Network Engineer Lila Sciences

Principal DevOps Engineer BitSight Technologies Inc

Principal DevOps Architect MKS Inc

Principal Thermal Mechanical Engineer JETCOOL Technologies

Principal Gifts Officer WGBH Boston

Principal Scientist, R&D Data, Data Science & Artificial Intelligence - Immunology Johnson & Johnson

Underwriting Principal Fifth Third Bank

Associate Principal Scientist, Clinical Research Merck & Co Inc

Principal Seller McKinstry Co.

VP, Principal Resilience Engineer Chubb Ltd

Principal Innovation Developer - Cloud & AI Hewlett Packard Enterprise Company

Intelligence Center X Principal - Americas Mendix Technology BV

Principal Audio DSP/ML Engineer- Audio Technology Bose Corporation, U.S.A

Principal Engineering Program Manager Hewlett Packard Enterprise Co

Principal Game AI Engineer Take-Two Interactive Software Inc

Principal Legal Counsel SS&C Technologies Holdings Inc

Associate Principal- Corporate Strategy Advisory Trinity Life Sciences

Test Architect Principal Cigna

Principal Electrical Engineer Re:Build Manufacturing

Principal Product Designer VIA

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