Principal - Cloud Engagement Lead, Microsoft - Healthcare and Life sciences EPAM Systems IncPrincipal - Cloud Engagement Lead, Microsoft - Healthcare and Life sciencesPhiladelphia, PABuild deep, durable relationships with Microsoft account teams, industry teams, and M1/M2 leadership; conduct joint account planning, schedule recurring cadences, meet face-to-face, and lead joint customer events (including ABM-style executive sessions for top accounts). Act as pursuit leader and player-coach on strategic deals, coordinating solution architects, practice leaders, delivery leadership, and pricing and commercial teams to deliver clear value articulation, competitive differentiation, and strong executive messaging.
Principal Investigator/Associate Director, Translational Biomarker Discovery Laboratory Incyte CorpPrincipal Investigator/Associate Director, Translational Biomarker Discovery LaboratoryWilmington, DEQualifications Minimal acceptable level of education work experience and competency • PhD or equivalent in Oncology Molecular Biology Systems Biology Immunology or a related life sciences discipline • 6-10 years of experience in translational research within pharma biotech or a comparable research environment • Strong demonstrable expertise in assay development optimization and implementation • Hands on experience with advanced molecular and cellular technologies and multi omic platforms • Proven ability to integrate biological data across multiple modalities to inform discovery and translational decisions • Experience working with human samples and clinically relevant model systems • Strong scientific communication skills and ability to collaborate effectively in matrixed teams Preferred • Experience supporting biomarker strategies for early clinical programs • Familiarity with oncology andor inflammatoryautoimmune disease biology • Experience interacting with toxicology DMB or CQP functions • Comfort working in a role that combines scientific independence with focused team oversight rather than large scale management Disclaimer The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. The Principal InvestigatorAssociate Director will primarily operate as a senior individual contributor with the potential to oversee a small team of laboratory scientists or matrixed contributors over time while remaining actively involved in experimental design assay execution and cross‑functional program support.
Principal Software Engineer Bentley Systems IncPrincipal Software EngineerPhiladelphia, PAFounded in 1984 by engineers for engineers, Bentley is the partner of choice for engineering firms and owner-operators worldwide, with software that spans engineering disciplines, industry sectors, and all phases of the infrastructure lifecycle. Responsibilities: Architect, develop and shape the future of the core Cesium Native C++ libraries, focusing on performance, modularity, and clean API design to support our integrations with Unreal Engine, Unity, and NVIDIA Omniverse.
Architectural Principal DesignBlendz ArchitectureArchitectural PrincipalPhiladelphia, PAThis leadership role is ideal for an experienced architect with deep expertise in multifamily, mixed-use residential, affordable housing, or market-rate housing sectors - and who is ready to guide a studio focused on shaping the future of where people live. Working closely with senior leadership, you will help expand our residential portfolio, strengthen client relationships, and ensure our studio delivers exceptional and innovative living environments.
Principal Applied AI Engineer, Finance Genesys Cloud Services IncPrincipal Applied AI Engineer, FinancePennsylvania, PA$225,200–$396,000 / yearThe ideal candidate is both a strategic technical leader and hands-on builder-capable of architecting complex AI systems with a software engineering mindset, influencing organizational direction, and delivering measurable business impact. Through Genesys Cloud, the AI-powered Experience Orchestration platform, organizations can accelerate growth by delivering empathetic, personalized experiences at scale to drive customer loyalty, workforce engagement, efficiency and operational improvements.
Principal Solutions Engineer Crane NXT CoPrincipal Solutions EngineerMalvern, PAPrincipal Solutions Engineer, CPI, Malvern, Pennsylvania: Responsible for: architecting & designing software solutions designed to support/enhance retail industry products, & gathering both customer & internal requirements & then design solutions that meet these requirements. Alternatively, would accept: Bachelor's degree in Computer Science, Engineering, or a related field & 5 yrs of software development exp in an object oriented environment in the retail payment industry: With either combination of education & exp, must have 5 yrs of exp.
Principal Cloud Cost Analyst Comcast CorpPrincipal Cloud Cost AnalystPhiladelphia, PAThat's why we provide an array of options, expert guidance and always-on tools that are personalized to meet the needs of your reality-to help support you physically, financially and emotionally through the big milestones and in your everyday life. Support validation and testing of cost models, dashboards, and automation outputs, partnering with engineering teams and business users to ensure solutions meet defined requirements and expected outcomes.
Managing Principal, Travel & Hospitality Consulting EPAM Systems IncManaging Principal, Travel & Hospitality ConsultingPhiladelphia, PABuild and expand trusted C-suite and senior stakeholder relationships within Travel, Hospitality, and Leisure clients (airlines, hotels, resorts, cruise, OTA, TMC, loyalty platforms), drive measurable value across existing accounts and identify industry-specific up-sell and cross-sell opportunities. Demonstrated expertise across Travel & Hospitality business functions, such as guest/customer experience & personalization, loyalty and CRM ecosystems, reservations, distribution, and booking platforms, revenue management, pricing, and demand forecasting, operations, workforce, and supply chain optimization.
Principal, Global Talent Hub Clinical Lead - Cigna Healthcare - Hybrid The Cigna GroupPrincipal, Global Talent Hub Clinical Lead - Cigna Healthcare - HybridPhiladelphia, PA$141,500–$235,900 / yearPartner across Clinical, Enterprise Strategy, Global Talent, and external vendors to define and evolve the global clinical operating model, including scope such as utilization management, case management, pharmacy support, and administrative services. These states include: Alabama, Alaska, Arizona, Arkansas, Delaware, Florida, Georgia, Hawaii, Idaho, Iowa, Kansas, Maryland, Massachusetts, Michigan, Nebraska, Ohio, Pennsylvania, Texas, Utah, Vermont, and Washington State.
Senior Principal Investigator, Drug Product Process Development Incyte CorpSenior Principal Investigator, Drug Product Process DevelopmentWilmington, DEOverview Job description The Senior Principal Investigator Drug Product Process Development will report to the senior director DP Technologies DPT in Global Biopharmaceutical Development GBD is a critical role in our development team and will help lead the successful development and commercialization of biologics product candidates. By accessing this link you can learn about the types of personal data we collect how we use it whether collection and processing is optional sources of the personal data we process how it is shared where it is stored or transferred to how long we keep it and contact information for Incyte Incytes data protection officer and your supervisory authority if applicable.
Principal AI & Automation Engineer Comcast CorpPrincipal AI & Automation EngineerPhiladelphia, PAThe Comcast Network and CONNECTivity (CONNECT) organization is a highly agile, fastpaced, dedicated group at the forefront of change focused on innovating, building, and operating the best in class, most reliable access network for our customers. You will combine deep automation expertise, modern software architecture, and AI/ML-driven testing approaches to transform complex system requirements into scalable, resilient, and insight-driven quality solutions.
Principal Engineer, SCADA Engineering (BESS) Invenergy LLCPrincipal Engineer, SCADA Engineering (BESS)Philadelphia, PA$155,000–$180,000 / yearThis role is accountable for defining and documenting control strategies and data interfaces between substation devices, generation resources, data centers, remote operation centers, and external entities, and for driving reliable data connectivity and control readiness from design, commissioning, and turnover. Monitor construction progress remotely and via on site visits, support resolution of field issues, attend in person meetings with stakeholders, and provide on-site programming and field support during commissioning when required.
Principal Product Manager Bentley Systems IncPrincipal Product ManagerPhiladelphia, PAWe're looking for a Principal Product Manager in Bentley's Platform team dedicated to being a liaison and advocate for Bentley Infrastructure Cloud (BIC) building deeply collaborative and iterative relationships built on authenticity, trust, and mutual success. Founded in 1984 by engineers for engineers, Bentley is the partner of choice for engineering firms and owner-operators worldwide, with software that spans engineering disciplines, industry sectors, and all phases of the infrastructure lifecycle.
Principal FinOps Analyst ComcastPrincipal FinOps AnalystPhiladelphia, PennsylvaniaThat's why we provide an array of options, expert guidance and always-on tools that are personalized to meet the needs of your reality—to help support you physically, financially and emotionally through the big milestones and in your everyday life. Support validation and testing of cost models, dashboards, and automation outputs, partnering with engineering teams and business users to ensure solutions meet defined requirements and expected outcomes.
Principal, Commercial Strategy Trinity Life SciencesPrincipal, Commercial StrategyEast Norriton, PA$188,000–$282,000 / yearThe Principal will also fulfill a highly strategic role in support of the firm's success by: identifying innovative initiatives and implementing those; contributing as a strategic business partner to senior management; and developing short and long term goals and spearheading the implementation of related activities. Trinity's salary bands account for a wide range of factors that are considered in making compensation decisions including but not limited to skill sets and market demand for skills; level of experience and training; specific qualifications, performance, time in role/company, geographic location, and other business and organizational needs.
Principal Investigator, Translational Biomarker Discovery Laboratory Incyte CorporationPrincipal Investigator, Translational Biomarker Discovery LaboratoryWilmington, DelawareThe Principal Investigator provides scientific and technical leadership by integrating multi‑omic analyses (e.g., transcriptomic, proteomic, and cellular profiling) with advanced assay development to define mechanism‑aligned biomarkers and pharmacodynamic readouts that inform target selection, exposure–response understanding, and early clinical strategy. The Principal Investigator will primarily operate as a senior individual contributor, with the potential to oversee a small team of laboratory scientists or matrixed contributors over time, while remaining actively involved in experimental design, assay execution, and cross‑functional program support.
Principal Machine Learning Engineer Delan Associates, IncPrincipal Machine Learning EngineerPhiladelphia, PAThis role will primarily focus on building, validating, deploying, and improving machine learning models, while also bringing principal-level judgment to problem definition, model design, stakeholder engagement, and production readiness. Principal Machine Learning Engineer to serve as a hands-on technical leader for machine learning, predictive modeling, scoring, decisioning, and applied AI initiatives.
NewPrincipal Supply Chain Planning Specialist Northrop Grumman CorpPrincipal Supply Chain Planning SpecialistElkton, MD$87,000–$130,600 / yearOversee all Supply Chain Management activities needed to meet program requirements and maintain link between various Supply Chain functions including Purchasing/Sub-Contracts, Logistics and Production Control. The above salary range represents a general guideline; however, Northrop Grumman considers a number of factors when determining base salary offers such as the scope and responsibilities of the position and the candidate''s experience, education, skills and current market conditions.
NewPrincipal Project Management Northrop Grumman CorpPrincipal Project ManagementElkton, MD$94,200–$141,200 / yearThe above salary range represents a general guideline; however, Northrop Grumman considers a number of factors when determining base salary offers such as the scope and responsibilities of the position and the candidate''s experience, education, skills and current market conditions. In this dedicated program role, serves as office manager and facilitator to streamline and conduct daily operations, logistics, facility maintenance, team communication via daily contact with the customer and multiple outside agencies.
NewPrincipal Program Cost Schedule Control Analyst Northrop Grumman CorpPrincipal Program Cost Schedule Control AnalystElkton, MD$89,900–$134,900 / yearPerforms data gathering and analysis to ensure adequate funding availability by maintaining accurate records of expenditures, preparation of expenditure projections, and submittal of timely requests for additional funding to the government. The above salary range represents a general guideline; however, Northrop Grumman considers a number of factors when determining base salary offers such as the scope and responsibilities of the position and the candidate''s experience, education, skills and current market conditions.