Professor Dana-Farber Cancer Institute IncProfessorBOSTON, MA$200,000–$450,000 / yearWe seek an internationally recognized scientist with an outstanding record of scholarship in any aspect of cancer biology, including but not limited to molecular and cellular biology, systems biology, immunology, chemical biology, structural biology, metabolism, genomics, proteomics and computational biology. Interested candidates should submit the following documents to the Committee chair, Dr. Bradley Bernstein, MD, PhD; Chair, DFCI Cancer Biology and Professor, HMS Cell Biology at CbS_Dfci@dfci.harvard.edu:
Human Genetics Laboratory Leader Novartis AGHuman Genetics Laboratory LeaderCambridge, MA$138,600–$257,400 / yearKey responsibilities: Lead and develop a high-performing team of 2-3 wet lab scientists, establishing state-of-the-art experimental capabilities to functionally characterize human genetic variationManage resources, priorities, and execution across multiple projects, ensuring high-quality data generation, interpretation, and delivery aligned with strategic goalsApply genetics expertise to enable recall-by-genotype strategies, including participant identification from biobank resources and design of deep phenotyping protocolsServe as senior scientific leader to evolve the genotype-to-phenotype research strategy, translating rare variants into biological hypotheses and target investment decisionsRepresent genetics expertise in cross-functional teams and governance boards, contributing to portfolio prioritization alongside computational biology and disease area expertsBuild and maintain strong internal and external partnerships, communicating scientific insights effectively to diverse audiencesEssential Requirements: PhD with 8+ years of post-graduate experience in genetics, with a focus on rare variants and/or genotype-to-phenotype translationStrong background in experimental biology, including cellular models and gene perturbation technologies relevant to variant characterizationExtensive experience connecting clinical and/or biobank genetic data to biological mechanisms and therapeutic hypotheses across disease indicationsProven people leadership skills, including mentoring and developing scientists, with the ability to influence cross-functional teams in a matrix environmentCuriosity for emerging technologies and methods, including AI-based approaches for variant interpretation and prioritizationExceptional collaboration, communication, and problem-solving skills, with a strong track record of scientific innovationDesirable Requirements:Hands-on experience in designing and executing recall-by-genotype studiesTarget and/or drug discovery experience in an industry settingThe salary for this position is expected to range between $138,600 and $257,400 USD annually for Senior Principal Scientist, and $152,600 and $283,400 USD annually for Associate Director. The successful candidate will lead a small team of biologists and shape the genotype-to-phenotype translation strategy, integrating rare variant genetics, functional biology, and advanced analytical approaches to inform target prioritization.
Scientist I - Fischer Lab Dana-Farber Cancer Institute IncScientist I - Fischer LabBOSTON, MA$80,000–$95,900 / yearThe Fischer Lab at Dana-Farber Cancer Institute is a Structural and Chemical Biology lab that combines molecular biology, computational biology, structural biology and chemistry with various 'Omics' techniques such as proteomics to study the pathways and protein complexes involved in protein homeostasis and the ubiquitin proteasome system often associated with human diseases, including cancer. We are affiliated with state of the art facilities for structural biology (cryo-EM, X-ray crystallography, NMR), chemistry, biophysics, cellular imaging, etc. and the lab also has expertise and equipment for mass spectrometry including timsTOF pro/ultra and Orbitrap Eclipse/zoom mass spectrometers.
Scientist II, Discovery & Platform Innovation Prime Medicine, Inc.Scientist II, Discovery & Platform InnovationCambridge, MA$131,000–$146,000 / yearResponsibilities will include editing strategy conception, pegRNA design and optimization, testing of Prime Editor protein constructs, optimization of mRNA constructs, and evaluation of other Prime Editing components to maximize editing efficiency, precision, and desired phenotypic outcome. Experience providing day-to-day scientific direction to research associates, interns, or co-op students, and comfort collaborating with and directing the work of external CROs; success operating within a lean, matrixed team, including dotted-line working relationships, is a plus.
Senior Scientist, Mrna Design & Platform Innovation Prime Medicine, Inc.Senior Scientist, Mrna Design & Platform InnovationCambridge, MA$145,000–$161,000 / yearExperience providing day-to-day scientific direction to research associates, interns, or co-op students, and comfort collaborating with and directing the work of external CROs; success operating within a lean, matrixed team, including dotted-line working relationships, is a plus. Excellent scientific communication skills, with the ability to present complex findings clearly to diverse audiences and contribute to written scientific outputs; strong publication and presentation record, with engagement in the broader scientific community (e.g., conferences, scientific societies).
NewIn Vivo Study Specialist Parabilis MedicinesIn Vivo Study SpecialistCambridge, MA$75,000–$85,000 / yearThis is a hands-on laboratory role built around two core skill sets: executing in vivo pharmacology studies in mouse oncology models, and preparing high-quality ex vivo assays from tumor and normal tissue for downstream molecular and immune analysis. We are fiercely independent as a leader in defying the limitations of current therapeutic modalities, and interdependent as a team as we work collaboratively to shift drug discovery paradigms and provide patients with better treatment options.
NewSenior Scientist, Multimodal Biological Reasoning Flagship Pioneering IncSenior Scientist, Multimodal Biological ReasoningCambridge, MA$136,000–$264,000 / yearFlagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Pioneering Intelligence is seeking a Senior Scientist for Flagship''s ambitious efforts to build polyintelligent AI systems that unify human scientific expertise, machine intelligence, and nature's biological signals into multi-modal, multi-scale reasoning engines for biology.
NewResearch Associate II, NGS Flagship Pioneering IncResearch Associate II, NGSCambridge, MA$74,000–$94,500 / yearThe company's initial therapeutic programs are designed to restore full-length protein production in diseases caused by premature termination codons (PTCs), collectively referred to as Stop Codon Disease, which affect approximately 10% of people with a rare genetic disease. Alltrna's NGS pipeline is central to company initiatives, and this role will collaborate closely with a cross-functional team of scientists in molecular biology, computational biology, and lab automation.
Senior Scientist, mRNA Design & Platform Innovation Prime MedicineSenior Scientist, mRNA Design & Platform InnovationCambridge, MA$145,000–$177,000 / yearExperience providing day-to-day scientific direction to research associates, interns, or co-op students, and comfort collaborating with and directing the work of external CROs; success operating within a lean, matrixed team, including dotted-line working relationships, is a plus. Excellent scientific communication skills, with the ability to present complex findings clearly to diverse audiences and contribute to written scientific outputs; strong publication and presentation record, with engagement in the broader scientific community (e.g., conferences, scientific societies).
Scientist II, Discovery & Platform Innovation Prime MedicineScientist II, Discovery & Platform InnovationCambridge, MA$131,000–$146,000 / yearResponsibilities will include editing strategy conception, pegRNA design and optimization, testing of Prime Editor protein constructs, optimization of mRNA constructs, and evaluation of other Prime Editing components to maximize editing efficiency, precision, and desired phenotypic outcome. Experience providing day-to-day scientific direction to research associates, interns, or co-op students, and comfort collaborating with and directing the work of external CROs; success operating within a lean, matrixed team, including dotted-line working relationships, is a plus.
Scientist Sr. Scientist, Cardiovascular and Metabolic Disease Flagship Pioneering IncScientist Sr. Scientist, Cardiovascular and Metabolic DiseaseCambridge, MA$100,000–$181,500 / yearFlagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Many of these companies have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
(Scientist) Sr. Scientist, Cardiovascular and Metabolic Disease Flagship Pioneering, Inc.(Scientist) Sr. Scientist, Cardiovascular and Metabolic DiseaseCambridge, MA USA$100,000–$181,500 / yearFlagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
(Senior) Scientist, Multimodal Biological Reasoning Flagship Pioneering, Inc.(Senior) Scientist, Multimodal Biological ReasoningCambridge, MA USA$136,000–$264,000 / yearFlagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Pioneering Intelligence is seeking a Senior Scientist for Flagship's ambitious efforts to build polyintelligent AI systems that unify human scientific expertise, machine intelligence, and nature’s biological signals into multi-modal, multi-scale reasoning engines for biology.
NewResearch Associate II, NGS Flagship Pioneering, Inc.Research Associate II, NGSCambridge, MA USA$74,000–$94,500 / yearThe company’s initial therapeutic programs are designed to restore full-length protein production in diseases caused by premature termination codons (PTCs), collectively referred to as Stop Codon Disease, which affect approximately 10% of people with a rare genetic disease. Alltrna’s NGS pipeline is central to company initiatives, and this role will collaborate closely with a cross-functional team of scientists in molecular biology, computational biology, and lab automation.
NewPioneering Medicines: Scientist / Sr. Scientist, Translational Sciences Flagship Pioneering IncPioneering Medicines: Scientist / Sr. Scientist, Translational SciencesCambridge, MA$100,000–$181,500 / yearFlagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Harnessing the drug development expertise of its team together with the power of Flagship''s multiple scientific platforms, Pioneering Medicines explores and identifies new product concepts which are then advanced jointly with Flagship's bioplatform companies.
Senior Data Scientist (AI-assisted Clinical Development) GenentechSenior Data Scientist (AI-assisted Clinical Development)Boston, MassachusettsYou have excellent collaboration skills, including statistical consulting skills, interpersonal skills to contribute effectively in cross-functional team settings, ability to influence others without authority, and ability to build strong collaborative relationships with scientific and non-scientific partners. You will partner closely with product managers, software engineers, and UX researchers to design, test, and scale statistical capabilities that unlock actionable insights from clinical, operational, and real-world data.
Principal Data Scientist (AI-assisted Clinical Development) Genentech IncPrincipal Data Scientist (AI-assisted Clinical Development)Boston, MA$169,100–$314,000 / yearYou have excellent collaboration skills, including statistical consulting skills, interpersonal skills to contribute effectively in cross-functional team settings, ability to influence others without authority, and ability to build strong collaborative relationships with scientific and non-scientific partners. You will partner closely with product managers, software engineers, and UX researchers to design, test, and scale statistical capabilities that unlock actionable insights from clinical, operational, and real-world data.
Principal Scientist, Pooled Functional Screening Flagship Pioneering IncPrincipal Scientist, Pooled Functional ScreeningCambridge, MA$163,000–$214,500 / yearThe successful candidate will have a strong track record designing large libraries for high-throughput screening as well as running pooled, FACS-based screens, from library production and transduction through selection, sequencing, and analysis (including culturing and screening in primary and primary-like cell lines). FL130 (Flagship Labs 130) is an early-stage biotechnology startup aiming to answer an ambitious and exciting question: What if… we could systematically identify bioactive peptides to inspire next-generation therapies and uncover novel targets?
NewPioneering Medicines: Scientist / Sr. Scientist, Translational Sciences (T-cell focused) Flagship Pioneering, Inc.Pioneering Medicines: Scientist / Sr. Scientist, Translational Sciences (T-cell focused)Cambridge, MA USA$100,000–$181,500 / yearFlagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Harnessing the drug development expertise of its team together with the power of Flagship's multiple scientific platforms, Pioneering Medicines explores and identifies new product concepts which are then advanced jointly with Flagship’s bioplatform companies.
Biomarker And Precision Medicine Lead SanofiBiomarker And Precision Medicine LeadCambridge, MA$178,500–$257,833.33 / yearBut progress doesn't happen without people - people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. Position Overview: The Biomarkers & Precision Medicine group at Sanofi, within the Translational Medicine Unit, seeks an experienced Biomarker and Precision Medicine Lead.