The University of Tennessee Health Science Center Memphis (UTHSC) faculty will work in collaboration with the UT-Oak Ridge Innovation Institute (UT-ORII), ORNL researchers and the University of Tennessee Knoxville (UTK) investigators to address the molecular mechanisms of cancer immunity affected by targeted alpha-radiation therapy of solid tumors. With six colleges - Dentistry, Graduate Health Sciences, Health Professions, Medicine, Nursing, and Pharmacy - at its main campus in Memphis, in addition to educational and clinical campuses at major hospitals in Memphis, Knoxville, Chattanooga, and Nashville, and sites across the state, UTHSC strives to fulfill its vision: Healthy Tennesseans.