The lab is based in Vanderbilt's Department of Cell and Developmental Biology and affiliated with the Center for Computational Systems Biology (CCSB), a trans-institutional center spanning Vanderbilt Basic Sciences, Vanderbilt University Medical Center, and the College of Connected Computing, placing the lab within a growing community of computational biologists, imaging scientists, and systems-level researchers on campus. The lab pursues this objective through atlas-scale multimodal data analysis: combining advanced microscopy, quantitative cell phenomics, spatial tissue profiling and multi-omics data; first-principles open-minded, curiosity-driven scientific inquiry integrating ideas across disciplines without borders, be it theoretical physics, philosophy, economics, biology, computing or mathematics.