Principal Scientist, Protein Design ModernaTXPrincipal Scientist, Protein DesignCambridge, MassachusettsThis role will lead the design, execution, and continuous advancement of high-throughput mammalian cell–based screening platforms that interrogate broadly applicable design principles for glycoprotein antigens, enabling antigen optimization, improved expression and durability across multiple programs, and rapid maturation of computationally designed candidates. The candidate in this position will work closely with and report to the Senior Director, Computational Design and In Vitro Selection, and will also work closely with the VP, Protein Design, as well as other members of Research, to advance novel candidates to the clinic, drive exploratory trials to inform the generation of improved vaccine antigens and explore new concepts for mRNA medicines.
Scientist, cDNA Display Manifold Bio IncScientist, cDNA DisplayBoston, MAResponsibilities: • Design, develop, and validate a cell-free display platform (cDNA display or similar) compatible with diverse binder formats • Work with automation team to scale and automate the platform to enable routine, high-throughput screening against large panels of therapeutic targets • Collaborate with ML and computational teams to ensure screening outputs feed effectively into model training pipelines • Work with the protein engineering team to support discovery campaigns and affinity maturation as platform capacity allows • Stay current on advances in cell-free display, laboratory automation, and computational protein design. Why you might be a good fit: Building systems that generate data at a scale previously impossible excites you You thrive in fast-moving environments where you own a problem end-to-end You are energized by working at the intersection of wet lab science, automation, and AI-driven biotherapeutic discovery You are a collaborative scientist who communicates well across teams with different technical backgrounds.
Research Scientist or Postdoctoral Associate in Formal Methods for Security and Machine Learning UMass LowellResearch Scientist or Postdoctoral Associate in Formal Methods for Security and Machine LearningLowell, MassachusettsAnitha Gollamudi at the Richard Miner School of Computer Science and Information, invites applications for a postdoctoral associate or research scientist position in the area of formal methods for security and machine learning. Special Instructions to Applicants: Only current UML Employees within the Grants & Contracts (MTA/GRACE) bargaining unit will be considered during the first 10 business days of the posting.
Machine Learning Engineer - Computational Drug Discovery 5AM VenturesMachine Learning Engineer - Computational Drug DiscoveryWatertown, MAOur team is dedicated to the development of a broad pipeline of small molecules powered by unique chemistry insights to address a wide range of highly unmet clinical needs. The ideal candidate is comfortable operating across disciplines, takes pride in building reliable systems, and appreciates the opportunity to have a direct impact on scientific decision-making.
Research Scientist, Strain and Enzyme Engineering ManusResearch Scientist, Strain and Enzyme EngineeringWaltham, MACross-Functional Collaboration: Communicate findings and work closely with colleagues across strain engineering, fermentation, analytical sciences, and downstream processing to accelerate development and improve experimental outcomes. In this role, you will apply creative, collaborative approaches to engineer microbial strains and enzymes, identify and overcome metabolic bottlenecks, and optimize pathways for improved biomanufacturing performance.
Associate Director Translational Genetics and Medicine Alnylam Pharmaceuticals IncAssociate Director Translational Genetics and MedicineCambridge, MA$202,300–$273,700 / yearThe Research Department at Alnylam is seeking a passionate and creative translational scientist or physician-scientist to join the Translational Genetics and Medicine Group and play a leading role in utilizing human data and clinical insights to enhance the discovery, validation, and prioritization of new therapeutic targets. Our team aims to enhance the translation of basic scientific discoveries in 1) human genetics by improving phenotyping and interpretation of genome-wide association results, and 2) biology by using human data for biomarker discovery, assessing unmet need, and guiding our preclinical strategy.
NewHead of Artificial Intelligence - ICC AstraZeneca PlcHead of Artificial Intelligence - ICCWaltham, MAYou will form a centralized group of AI experts embedded with R&D teams, orchestrate initiatives from agentic knowledge hubs to predictive CAR-T models and in silico binder design, and establish the governance and operating rhythm that turns prototypes into durable platforms and outcomes. Portfolio Orchestration: Prioritize and deliver a focused slate of initiatives including agentic knowledge hubs, predictive modeling for cell therapy, in silico protein and binder design, TCR affinity maturation, CRISPR off-target safety, and next-generation analytics.
Staff Data Scientist, Clinical Performance Latitude Health IncStaff Data Scientist, Clinical PerformanceBoston, MA$160,000–$200,000 / yearWhile your primary focus is evaluative, you will be a key player in the broader clinical DS ecosystem, collaborating on patient risk stratification and building the forecasting engines that predict our quality performance across various value-based care programs. Automate Model Lifecycles with AI Agents: Architect and oversee AI-driven agents that autonomously manage the end-to-end lifecycle of our statistical models - leveraging automation for continuous training, deployment, performance monitoring, and proactive model refreshes.
NewSenior Principal Research Scientist Northrop Grumman CorpSenior Principal Research ScientistMA$142,200–$213,400 / yearThe above salary range represents a general guideline; however, Northrop Grumman considers a number of factors when determining base salary offers such as the scope and responsibilities of the position and the candidate''s experience, education, skills and current market conditions. You will lead or support ceramics research efforts through formulation development and materials fabrication, and execution of test procedures and data analysis for the advancement of functional and structural ceramics used in AOX's products.
Data Scientist Layer HealthData ScientistBoston, Massachusetts$180,000–$200,000 / yearDevelop, validate, and measure the impact of large language model (LLM) and other ML-based approaches for chart abstraction from both unstructured and structured healthcare data. Deep fluency and instincts for data manipulation, treatment, and evaluation, with the ability to wrangle large, complex datasets efficiently and methodically.
Scientist Metabolomics Alnylam Pharmaceuticals IncScientist MetabolomicsCambridge, MA$110,400–$165,600 / yearDirect experience with triple-quadrupole and high-resolution accurate mass LC-MS/MS-based methods for endogenous metabolite/lipid quantification (ideally with Sciex QTRAP and Thermo Orbitrap systems), including assay development and validation. We use untargeted and targeted liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based omics and computational biology to support biomarker discovery and target validation efforts for our RNAi-based therapeutics.
Medical Director, Clinical Development Oncology, Cambridge, MA Isomorphic Labs LimitedMedical Director, Clinical Development Oncology, Cambridge, MACambridge, MAAt IsoLabs, we are committed to leveraging state-of-the-art AI to advance precision medicine paradigms and establish new benchmarks for both efficacy and safety by consistently delivering the optimal treatments to the appropriate patients at precisely the right time, which we expect to significantly enhance our overall probability of success. By harnessing AI's powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drug candidates will perform in the clinic and develop medicines to treat and cure some of the world's most devastating diseases.
Analyst, Decision Science George P. Johnson Experience MarketingAnalyst, Decision ScienceBoston, MA$85,000–$115,000 / yearYou will work on high-profile internal initiatives like our proprietary insights platform, centralizing experiential data into unified structures, and building robust, big-data pipelines to help our clients make better business and experience design decisions. You'll partner with strategists, creatives, and account teams to turn messy, physical-world interaction data into clear, compelling narratives that prove the value of experiences and shape future brand decisions.
Senior Data Scientist Mitre CorpSenior Data ScientistBedford, MA$124,400–$155,500 / yearMITREs Data Science and Engineering department is looking for qualified applicants to bring their advanced data science, data engineering, machine learning, artificial intelligence, and applied research skills to bear on solving problems of critical national importance. Preferred Qualifications: Masters degree in Computer Science, Applied Mathematics, Statistics, Data Science, or related field with 3 years of relevant experience; PhD in Computer Science, Applied Mathematics, Statistics, Data Science, or related field.
Senior Data Scientist - ML/AI Digital Workplace Experience CVS Health CorpSenior Data Scientist - ML/AI Digital Workplace ExperienceMABenefit solutions that address the different needs and preferences of our colleagues including paid time off, flexible work schedules, family leave, dependent care resources, colleague assistance programs, tuition assistance, retiree medical access and many other benefits depending on eligibility. Benefit solutions that address the different needs and preferences of our colleagues including paid time off, flexible work schedules, family leave, dependent care resources, colleague assistance programs, tuition assistance, retiree medical access and many other benefits depending on eligibility.
Lead Data Scientist Mitre CorpLead Data ScientistBedford, MA$155,200–$194,000 / yearPreferred Qualifications: Masters degree in Computer Science, Applied Mathematics, Statistics, Data Science, or related field with 6 years of relevant experience; PhD in Computer Science, Applied Mathematics, Statistics, Data Science, or related field with 3 years of relevant experience. MITREs Data Science and Engineering department is looking for qualified applicants to bring their advanced data science, data engineering, machine learning, artificial intelligence, and applied research skills to bear on solving problems of critical national importance.
Senior Scientist I - Upstream Processing Novartis AGSenior Scientist I - Upstream ProcessingCambridge, MAJob ID REQ-10083717 Jul 23, 2026 Slovenia Available in: English Summary #LI-Hybrid Location: Menges, Slovenia Interni naziv pozicije / Internal job title: Raziskovalec ekspert I / Senior Scientist IRole Purpose:Our R&D unit in Menge is looking for a motivated scientist in field of Upstream Processing (USP) to join us and help...
Senior Research Associate, Analytical Development - Separation Sciences Takeda Pharmaceutical Co LtdSenior Research Associate, Analytical Development - Separation SciencesLexington, MA$89,900–$141,240 / yearYou will bring hands-on laboratory experience, strong documentation practices, technical curiosity, and the ability to develop deeper expertise in separation sciences methods such as U/HPLC, SEC, IEX, RP, HIC, CE-SDS, icIEF, cIEF, glycan profiling, or related analytical technologies. What you bring to Takeda: Associate degree with 4+ years, bachelor's degree with 2+ years, or master's degree with 0+ years of relevant industry experience in analytical chemistry, biochemistry, protein chemistry, biologics analytical development, quality control, or a related discipline.
Sr. Scientist - Gene Delivery AstraZeneca PlcSr. Scientist - Gene DeliveryWaltham, MA$116,284–$174,426 / yearEducation and experience: PhD with 0-5 years of post-graduate experience in a relevant field, including but not limited to bioengineering, chemical engineering, biomedical engineering, molecular biology, synthetic biology, biochemistry, and immunology. This is where you'll find newly designed, activity-based workspaces to suit a variety of working styles while increasing collaboration between teams and the greater research community.
AIRx Director, Computational & AI Biologics Design Lead 3316 Takeda Development Center AmericasAIRx Director, Computational & AI Biologics Design LeadBoston, MassachusettsThis role drives in silico biologics design, applies generative AI and structure-informed methods to antibody and large-molecule programs, and connects Takeda’s internal AI/ML platform capabilities to the day-to-day decisions of a fast-moving drug-hunting team. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.