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Science Jobs in California

Drug Development Training Program, Computational Sciences

Genentech

South San Francisco, CA

D. in a quantitative discipline (Computer Science, Biology, Chemistry, Statistics, Mathematics, etc.)Adept at combining data visualization, scientific data analysis, and coding with an interest in developing user-friendly tools that drive discovery and data-driven decision makingPossess a strong intuition for reasoning about data to extract meaningful insights from complex datasets and explain them to others, ideally in a biological or chemical domain (drug discovery and development, omics, informatics, or other quantitative fields)Experienced in designing and creating static and/or interactive visualizations using modern technologies (JavaScript: D3.js, Vega/Vega-Lite, Plotly; R: Shiny, ggplot2; and/or Python: Streamlit, Dash, Altair, Seaborn, Bokeh, etc.)Proficient in data wrangling, processing, and analysis using Python and/or R (preferably in a scientific context)Experienced in collaborating with diverse, multidisciplinary teams (e.g., participation in a multi-lab team, member of a multi-institute consortium)Curious: enthusiastic for developing new skills and experiences as a Computational Scientist in a drug development organizationKeen about educating others on the possibilities and limitations of data visualizationThis role sits at the crossroads of drug development, data science and analysis, design, and engineering. Experience in the following areas is beneficial, but not required:Understanding of information processing, human/computer interaction, and human perception principles and methodologyProficiency with accessing, analyzing, and visualizing large amounts of dataExperience in modern web frameworks (Svelte, Vue, React, Angular)Experience with consuming and integrating with APIsFamiliarity with UI/UX design best practices, user-centric design, and usability testingFamiliarity with statistical analysis techniques and toolsFamiliarity with engineering best practices, including version control, testing, and working in cloud-based environmentsUnderstanding of machine learning and AI; experience integrating AI-based tools to solve data and coding problemsHow to Apply: CV listing publication record (no max on page limit), required Cover letter (2-pages max) expressing your interest in the position and your future career plans, optional but strongly encouragedTitle Your PDF “First Name_Last Name_DDTP_Application” (e.g.

Today
Senior Principal Scientist, Human Genetics

Genentech

South San Francisco, CA

Collaborate extensively with the Human Genetics team and other scientific and leadership teams to integrate genetic and genomic insights into therapeutic development. Who You AreYou are a PhD with a strong focus on statistical genetics, genetic epidemiology, computational biology, cardiovascular medicine, or related fields.

Today
Drug Development Training Program, Translational Medicine

Genentech

South San Francisco, CA

In 2025, we are hiring 3 positions in Translational Medicine (Omni-Biomarker), Development Sciences (Translational Safety) and gRED Computational Sciences (Computational Catalyst).The aim of the DDTP is to bring Early-in-Career doctoral graduates (PhD, MD/PhD, DVM or equivalent) to Genentech for hands-on training and mentorship in specific functions involved in multiple areas of pre-clinical and clinical drug development. The successful candidate will complete a lab-based project and acquire critical knowledge of the core techniques and biological assays required to establish disease-oriented, translational research models of Inflammatory Bowel Disease (IBD) with potential to characterize our portfolio molecules, deliver pathway biomarkers and discover new biology that can impact our current and future pipeline.

Today
Drug Development Training Program, Computational Toxicology

Genentech

South San Francisco, CA

Who You Are: PhD degree in (Computational) Toxicology, Chemistry, Biological Sciences or related fieldFamiliarity with safety relevant data from both in vitro and in vivo sources and understanding their translational relevance desiredExperience in programming languages such as Python or RPreferred Qualifications:Strong academic performance and publication record requiredExperience working in research labs or industrial biotech internshipsStrong interest in learning drug development and pursuing a career in industryDemonstrated leadership skills and desire to help patients and their local communitiesExcellent communication, collaboration, and interpersonal skills. In 2025, we are hiring 3 positions in Translational Medicine (Omni-Biomarker), Development Sciences (Translational Safety) and gRED Computational Sciences (Computational Catalyst).The aim of the DDTP is to bring Early-in-Career doctoral graduates (PhD, MD/PhD, DVM or equivalent) to Genentech for hands-on training and mentorship in specific functions involved in multiple areas of pre-clinical and clinical drug development.

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Senior Research Associate/Scientist I – Preclinical Pharmacology

Nurix Therapeutics

San Francisco, CA

The candidate will be expected to work independently and collaboratively across multiple Nurix groups (Discovery Biology, Medicinal Chemistry, DMPK), and to generate high quality, impactful results in an exciting and fast-paced research environment. The ideal candidate will have expertise in pharmacological profiling of small molecule drugs, xenograft and syngeneic tumor models, mammalian cell and molecular biology, and mechanisms of disease in oncology and inflammation.

13 days ago
Associate Director/Director, Clinical Science

Nurix Therapeutics

San Francisco, CA

Advanced degree in clinical or biological sciences (MD, PhD, or PharmD preferred) and 4+ year's (Associate Dir) or 8+ years (Director) relevant drug development experience with minimum of 3 years’ experience in oncology clinical trials. This role will work cross-functionally and participate in the execution of clinical studies including protocols, provide scientific expertise to support site and CRA training, data cleaning/analysis, investigator interaction and support of regulatory filings.

13 days ago
Cheminformatics Scientist

Nurix Therapeutics

San Francisco, CA

The successful candidate will collaborate extensively with teams in DEL, machine learning, IT & informatics, medicinal chemistry, and early discovery, contributing to all stages of the drug discovery pipeline, from library design and data analysis to hit identification and lead optimization. While the primary emphasis of this role will be supporting our DNA Encoded Library (DEL) and DEL-AI platforms, the successful candidate will additionally advance broader cheminformatics support for our degrader discovery and development teams.

2 days ago
Machine Learning Scientist

Nurix Therapeutics

San Francisco, CA

Demonstrated Python proficiency and experience with modern frameworks for Machine Learning: Proven experience implementing projects with supervised and unsupervised learning algorithms using modern python packages (e.g., linear regression, logistic regression, support vector machines, random forests, clustering, deep learning, scikit-learn, PyTorch, Tensorflow). This involves collaborating closely with interdisciplinary project teams, identifying critical research challenges amenable to machine learning solutions, developing high-quality predictive models, and deploying these models to streamline the drug design process.

2 days ago
Scientist I – Bioconjugate Chemist (Contractor) – Discovery Chemistry

Nurix Therapeutics

San Francisco, CA

Experience working with bioanalytical tools such as hydrophobic interaction chromatography (HIC), preparative-scale size exclusion chromatography (SEC), liquid chromatography-mass spectrometry (LC-MS), ion-exchange (IEX), and reversed phase (RP)-HPLC, Nuclear Magnetic Resonance (NMR) Spectroscopy. The successful candidate will have the opportunity to directly contribute to the following key platform operations: Develop, optimize and implement high-throughput bioconjugation processes through the application of established and state-of-the-art technologies.

30 days ago
Senior Machine Learning Scientist

Nurix Therapeutics

San Francisco, CA

Excellent communication, presentation, and interpersonal skills with the ability to effectively communicate complex technical concepts to both technical and non-technical audiences. Stay at the forefront of cutting-edge research in machine learning, attending conferences, reviewing publications, and actively participating in the scientific community.

2 days ago
Bioinformatics Scientist - Proteomics - Drug Discovery Technologies

Nurix Therapeutics

San Francisco, CA

The candidate will creatively expand the capabilities of Nurix’s proteomics platform by integrating and developing customized tools for both global and targeted proteomics data analysis workflows. Expertise in:Bioinformatics analysis of proteomic datasets with a focus on global proteomics workflows; familiarity with targeted proteomics is also valuable.

13 days ago
Sr Scientist/Principal Scientist, Chemical Development

Nurix Therapeutics

San Francisco, CA

PhD with 5-7 years of experience or MS with 10+ years of experience; advanced degree in Organic Chemistry, Chemical Engineering, Pharmaceutical Chemistry, Pharmaceutics, Pharmaceutical Science, or related scientific discipline, 3-5 years relevant experience in a pharmaceutical or biotechnology CMC/cGMP environment preferred. Excellent written and verbal communication skills, exceptional interpersonal and management skills to collaborate with and direct the work of others on assigned projects (including both internal teams and external collaborators).

2 days ago
Senior Scientist/Associate Director, Clinical Biomarkers

Nurix Therapeutics

San Francisco, CA

As a leader in the Clinical Biomarkers team, the successful candidate will collaborate across research, clinical development, and external partnerships to drive the biomarker strategy for early phase clinical trials, with a strong emphasis on immune-mediated and inflammatory diseases. Collaborate closely with multidisciplinary teams, including research scientists, clinical development, external collaborators, and contract research organizations (CROs), to ensure seamless integration of biomarker data into clinical development plans.

2 days ago
Scientist I/Scientist II, Chemical Development

Nurix Therapeutics

San Francisco, CA

The candidate will be responsible for chemical development-related activities across the portfolio including process development and manufacture of regulatory starting materials (RSMs) and supporting production of Drug Substance (DS) for clinical trial materials, and establishment of associated control strategy for RSMs and DS to support CMC regulatory documents. PhD with 2+ years of experience or MS with 5+ years of experience; advanced degree in Organic Chemistry, Chemical Engineering, Pharmaceutical Chemistry, Pharmaceutics, Pharmaceutical Science, or related scientific discipline, 1-3 years relevant experience in a pharmaceutical or biotechnology CMC/cGMP environment preferred.

13 days ago
Translational Sciences Intern

Maze Therapeutics

South San Francisco, CA

The company is advancing a pipeline using its Compass platform, which allows it to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process it refers to as variant functionalization. Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity.

20 days ago
Protein Sciences Intern

Maze Therapeutics

South San Francisco, CA

About Maze TherapeuticsMaze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. The company is advancing a pipeline using its Compass platform, which allows it to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process it refers to as variant functionalization.

20 days ago
Statistical Genetics Intern

Maze Therapeutics

South San Francisco, CA

About Maze TherapeuticsMaze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. The company is advancing a pipeline using its Compass platform, which allows it to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process it refers to as variant functionalization.

20 days ago
Senior Director, Clinical Sciences

Maze Therapeutics

South San Francisco, CA

About Maze TherapeuticsMaze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. The company is advancing a pipeline using its Compass platform, which allows it to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process it refers to as variant functionalization.

2 days ago