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Senior IT Jobs in Ashland, MA

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ITSM Operations Analyst Senior - IT - Full Time SolutionHealth

About the Job: The Senior IT Service Management (ITSM) Operations Analyst serves as a highly detail-oriented individual contributor responsible for designing, leading, coordinating, and reinforcing the execution of IT service management (ITSM) processes, with primary focus on Incident Management, Major Incident Response (IROC), Problem Management, and Change Enablement. This position serves as a designated Incident Commander and operational authority during service disruptions, ensuring incidents are triaged, escalated, communicated, and resolved in a timely, structured, and consistent manner.

30+ days ago

Senior IT Auditor Axon Enterprise Inc

Boston, MA

$94,140–$150,624 / year

This is a hands-on role for someone who enjoys going beyond traditional audit testing: understanding how complex processes and systems actually work, using data and emerging technology to make audits smarter, and partnering with teams to solve meaningful problems. If you receive a suspicious offer or outreach from an email address that is not @axon.com, or if you are asked for sensitive personal information (bank details, Social Security Number) prematurely, please ignore the message and report it to recruitingops@axon.com.

30+ days ago

Senior IT & Security Engineer (Robotics) Tutor Intelligence

Watertown, MA

$100,000–$300,000 / year

Own the network: The office network, the encrypted mesh that reaches every robot in the field, and each customer site''s integration with its own IT: VLANs, firewall rules, egress policy, certificates, and the documentation a customer''s network team needs to approve a deployment. Comfort with AI coding agents: You have used tools like Claude Code or similar for real engineering work, directing agents through multi-step tasks.

30+ days ago

Senior IT Security Analyst Bausch & Lomb

Bridgewater, MA

$120,000–$135,000 / year

This role serves as a subject matter expert for OT cybersecurity and partners with engineering, manufacturing, infrastructure, and cybersecurity teams to assess risks, implement security controls, and support secure and reliable manufacturing operations. We have a significant global research, development, manufacturing and commercial footprint of approximately 13,000 employees and a presence in approximately 100 countries, extending our reach to billions of potential customers across the globe.

30+ days ago

Senior IT Project Manager Harvard University

Cambridge, MA

Harvard University Information Technology (HUIT) is a community of Information Technology professionals committed to understanding our users and devoted to making it easier for faculty, students, and staff to teach, research, learn, and work through the effective use of information technology. The Senior PM partners closely with the Associate Director of Operational Excellence, service owners, and senior leaders to translate priorities into executable plans, track delivery, manage risk, and improve operational consistency.

30+ days ago

Sr. Manager - IT Commercial and Medical Systems Genetix Biotherapeutics

Somerville, Massachusetts

$147,000–$187,000 / year

Success in this role requires a strategic mindset balanced with hands-on resourcefulness, excellent communication and influencing skills, and a proven ability to drive cross-functional collaboration — ensuring technology investments deliver measurable business value and support data-driven decision-making across the organization. They bring working familiarity with CRM and business systems concepts, are comfortable using process mapping to diagnose issues and design better workflows, and know how to use AI tools to quickly learn new domains, prototype solutions, and close skill gaps in real time.

30+ days ago

Sr Systems Analyst, IT Clinical Regulatory Medical Alkermes Plc

Waltham, MA

In 2024 and 2025, we were certified as a Great Place to Work in the U.S. and named one of Massachusetts' Top Places to Work by the Boston Globe, a Best Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma by Fortune Magazine. Their role will include but not be limited to working with the various scientific areas to identify key data sets, facilitating the implementation of required infrastructure/solution where necessary, and working closely with the scientists and other users to understand their business needs.

30+ days ago

IT Risk Senior Associate (SOX & Internal Audit) Grant Thornton International Ltd

Boston, MA

$101,200–$129,030 / year

Your day-to-day may include: Actively participate in client engagements from start to completion, with a focus on executing and reporting on assigned project tasks that include co-sourced and outsourced IT internal audit, IT internal control assessments, IT risk management program assessments, tests of IT control design and operating effectiveness for Sarbanes-Oxley (SOX) and other compliance requirements, and helping clients design and implement IT controls. In the U.S., Grant Thornton delivers professional services through two specialized entities: Grant Thornton LLP, a licensed, certified public accounting (CPA) firm that provides audit and assurance services ― and Grant Thornton Advisors LLC (not a licensed CPA firm), which exclusively provides non-attest offerings, including tax and advisory services.

7 days ago

Senior Solutions IT Architect supporting Capacity Growth-Remote, Domestic US Locations RTX Corp

Remote

Exercise and exhibit a strong knowledge of: Virtualization (VMware, Hyper V, or similar), Classified Cloud Capabilities, Cross Domain Solutions (CDS), Storage solutions (SAN/NAS), Identity and access management (AD, PKI, MFA), RMF, NIST, ICD, and DoD cybersecurity frameworks. Extensive experience with Microsoft Windows, Red Hat, Ansible, VMware, Containerization, Cloud Native Architectures and Netapp Storage devices; Architectural and Security certifications such as TOGAF, Security+, and CISSP.

30+ days ago

Senior Discovery IT System Administrator (Top Secret Clearance Required) CONTACT GOVERNMENT SERVICES

Boston, MA

$160,579.80–$231,948.60 / year

For the past seven years, we've been growing our government-contracting portfolio, and along the way, we've created valuable partnerships by demonstrating a commitment to honesty, professionalism, and quality work. Here at CGS we value honesty through hard work and self-awareness, professionalism in all we do, and to deliver the best quality to our consumers mending those relations for years to come.

30+ days ago

US - Staffing - IT Sr Automation Engineer Axelon Services Corporation

Boston, MA

Remote

$92.85–$96.42 / hour
Quick Apply

Integrate LLM APIs (OpenAI, Anthropic Claude, Azure OpenAI) and AI-native patterns — including RAG pipelines, function calling, and streaming interfaces — into automation and operational tooling where applicable. Serve as the primary technical owner for production automation stability — proactively monitoring, triaging, and resolving incidents to maintain zero-defect delivery posture across all live bots.

10 days ago

Senior Vice President, IT Viridian Therapeutics Inc

Waltham, MA

This leader will oversee IT operations, enterprise applications, cybersecurity, AI governance, data strategy, GxP-regulated systems, and workplace services, while serving as a strategic advisor to executive leadership on technology, risk, operational scalability, and commercial readiness. Manage governance for AI, automation, data management, analytics, and emerging technologies to enable responsible adoption, risk management, data protection, vendor oversight and measurable value realization (partnering with legal, compliance, quality and other similar departments as needed).

30+ days ago

Senior Systems Analyst (R&D IT - Clinical, Regulatory, Medical) Alkermes

Waltham, MA

$105,000–$119,000 / year

30+ days ago

Senior Director, IT Business Solutions & Delivery Axon

Boston, MA

$191,340–$306,144 / year

You'll lead the Business Solutions Architecture (BSA), Program Management Office (PMO), and Quality Assurance (QA) organizations - the three functions that shape how technology projects are prioritized, delivered, and trusted across Axon's critical operational and go-to-market platforms. If you receive a suspicious offer or outreach from an email address that is not @axon.com, or if you are asked for sensitive personal information (bank details, Social Security Number) prematurely, please ignore the message and report it to recruitingops@axon.com.

22 days ago

Sr. Manager - IT bluebird bio, Inc.

Somerville, MA

$170,000–$185,000 / year

Partner with Quality and application owners on infrastructure for validated systems (LIMS/ELN, statistical computing, lab instruments), including server builds, security hot fixes, non-production testing, regression sign-off, and change control. You will lead identity, endpoint, backup and recovery, network, and cloud operations during a period of active modernization, including a move of identity services toward Microsoft Entra, a rebuild of backup and DR, and hardening of both corporate and laboratory environments.

4 days ago

Senior IT Project Manager - Salesforce SMART TECH SKILLS LLC

Marlborough, MA

Full time

Salesforce Implementations • Project Management • Agile • Scrum • Waterfall • Budget Management • Risk Management • Vendor Management • Release Management • Microsoft Project • SharePoint Online • Teams • Office 365 • Change Management • Testing Coordination • Stakeholder Engagement • Contract Management • Public Sector IT. The Project Manager will be responsible for driving end-to-end project execution, coordinating business and technical stakeholders, managing vendor relationships, tracking budgets and deliverables, mitigating risks, and ensuring the successful deployment of a large-scale Salesforce solution.

25 days ago

Sr Manager, IT Applications - OTC (SAP) Rich Products Corp

$150,889–$226,334 / year

Manage and guide small cross functional teams of technical and process specialists, system integration partners and vendors to deliver tasks, managed work packages, system upgrades and participate in larger delivery programmes. In this hands on role, you will lead the architecture and delivery of SAP S/4HANA solutions that enable efficient order-to-cash processes, drive operational excellence, and support our global growth strategy.

23 days ago

Sr. Manager, IT Infrastructure & Ops (Remote) The Panther Group

Chelmsford, MA

Remote

Quick Apply

Our client, a global customer experience and business process services company, is seeking a Senior Manager, IT Infrastructure & Cloud to support its ongoing technology modernization and cloud transformation initiatives. Oversee infrastructure operations, including servers, networking, storage, virtualization, and hybrid environments.

14 days ago

IT Assurance Senior Manager, Technology Risk Assurance BDO USA PC

Boston, MA

$160,000–$180,000 / year

Job Summary: The Assurance Senior Manager, Technology Risk Assurance is responsible for acting as an IT audit technical resource to clients, as well as internal stakeholders (Assurance teams), in the resolution of complex and high-level tasks associated with the audit process. Applies advanced knowledge and understanding of governing principles; applying these principles to client transactions; and documenting and communicating an understanding and application of these principles by: Plans and executes IT audits, including obtaining an understanding of the control environment, designs test plans, evaluates deficiencies, and assesses the overall financial reporting control environment.

30+ days ago

Senior IT & AI Systems Engineer CloudZero

Boston, Massachusetts

You'll build the layer that ends that: governed pipelines into Snowflake, a modeled surface analysts and agents can query without guessing at joins, and the environments where agents run with real identity and real cost attribution. The cloud perimeter: account structure, SCPs, IAM, and network segmentation for our major cloud providers (AWS, Azure, Snowflake), plus a Security partnership where new tooling is safe by default rather than safe by review.

30+ days ago

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Senior IT Jobs in Ashland, MA

ITSM Operations Analyst Senior - IT - Full Time SolutionHealth

Senior IT Auditor Axon Enterprise Inc

Senior IT & Security Engineer (Robotics) Tutor Intelligence

Senior IT Security Analyst Bausch & Lomb

Senior IT Project Manager Harvard University

Sr. Manager - IT Commercial and Medical Systems Genetix Biotherapeutics

Sr Systems Analyst, IT Clinical Regulatory Medical Alkermes Plc

IT Risk Senior Associate (SOX & Internal Audit) Grant Thornton International Ltd

Senior Solutions IT Architect supporting Capacity Growth-Remote, Domestic US Locations RTX Corp

Senior Discovery IT System Administrator (Top Secret Clearance Required) CONTACT GOVERNMENT SERVICES

US - Staffing - IT Sr Automation Engineer Axelon Services Corporation

Senior Vice President, IT Viridian Therapeutics Inc

Senior Systems Analyst (R&D IT - Clinical, Regulatory, Medical) Alkermes

Senior Director, IT Business Solutions & Delivery Axon

Sr. Manager - IT bluebird bio, Inc.

Senior IT Project Manager - Salesforce SMART TECH SKILLS LLC

Sr Manager, IT Applications - OTC (SAP) Rich Products Corp

Sr. Manager, IT Infrastructure & Ops (Remote) The Panther Group

IT Assurance Senior Manager, Technology Risk Assurance BDO USA PC

Senior IT & AI Systems Engineer CloudZero

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