Senior Director, Clinical Operations Keros TherapeuticsSenior Director, Clinical OperationsLexington, MA$253,000–$300,000 / yearWith a focus on developing differentiated product candidates that are designed to alter TGF- signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. As the leader of the cross-functional Clinical Program Team, the Senior Director Clinical Operations (SDCO) will lead the planning and execution strategy of assigned clinical trials to achieve overall program and corporate objectives.
Senior Director, Clinical Operations Alira HealthSenior Director, Clinical OperationsBoston, MA$175,000–$195,000 / yearThe Senior Director, Clinical Operations provides oversight of Clinical Development Operations, Nonclinical Development, Regulatory Affairs, Quality Assurance, Manufacturing/CMC Operations, and Program Management, while partnering closely with R&D, Finance, Investor Relations, Legal, and the CEO to ensure efficient execution of corporate objectives. This role is accountable for translating the clinical operations strategy into operational execution, driving cross-functional alignment, ensuring compliance with global regulatory requirements, maintaining operational excellence, and supporting the advancement of the Company's development pipeline from research through commercialization.
Senior Product Manager - Veeva Clinical Operations Veeva SystemsSenior Product Manager - Veeva Clinical OperationsBoston, MA$120,000–$200,000 / yearUnlike a traditional corporation, whose only legal duty is to maximize shareholder value, PBCs consider their public benefit purpose and the interests of those materially affected by the corporation's conduct-including customers, employees, and the community-in addition to shareholders' interests. We're not just any public company - we made history in 2021 by becoming a public benefit corporation (PBC), legally bound to balancing the interests of customers, employees, society, and investors.
Senior Director, Clinical Operations Aditum BioSenior Director, Clinical OperationsCambridge, Massachusetts or Oakland California$275,000–$285,000 / yearReporting to the SVP, Clinical Development Operations, this individual will independently lead the clinical operations strategy and execution for assigned programs spanning clinical pharmacology studies (first-in-human, SAD/MAD, PK/PD, drug-drug interaction) and Phase I/II patient studies, partnering closely with portfolio company leadership and cross-functional teams to deliver high-quality clinical trials on time and within budget. The Senior Director, Clinical Operations will provide strategic and operational leadership for the planning and execution of assigned early-stage clinical development programs across Aditum Bio's portfolio of biotechnology companies.
Director, Clinical Operations Oruka Therapeutics IncDirector, Clinical OperationsWaltham, MA$213,000–$240,000 / yearSignificant experience with cross-functional leadership and clinical teams, including leading data review, protocol deviation review, database lock, CSR development, and study reporting activities. Role Overview: We are seeking an exceptionally nimble and flexible Director of Clinical Operations who has a track record of achievement across all aspects of trial setup and execution in a fast paced small biotech with limited infrastructure and resources.
Director, Clinical Operations Oruka TherapeuticsDirector, Clinical OperationsWaltham, Massachusetts$213,000–$240,000 / yearSignificant experience with cross-functional leadership and clinical teams, including leading data review, protocol deviation review, database lock, CSR development, and study reporting activities. Oruka’s mission is to offer patients suffering from chronic skin diseases like plaque psoriasis the greatest possible freedom from their condition by achieving high rates of complete disease clearance with dosing as infrequently as once or twice per year.
Product Marketing Manager / Senior Manager - Clinical Operations Veeva SystemsProduct Marketing Manager / Senior Manager - Clinical OperationsBoston, MA$75,000–$150,000 / yearUnlike a traditional corporation, whose only legal duty is to maximize shareholder value, PBCs consider their public benefit purpose and the interests of those materially affected by the corporation's conduct-including customers, employees, and the community-in addition to shareholders' interests. We're not just any public company - we made history in 2021 by becoming a public benefit corporation (PBC), legally bound to balancing the interests of customers, employees, society, and investors.
Associate Director, Clinical Operations Kymera Therapeutics IncAssociate Director, Clinical OperationsWatertown, MA$160,000–$240,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Work closely with translational medicine team to ensure appropriate incorporation of bioanalytical sampling plan into clinical protocols and relevant data output of the trial is provided to functional groups for review.
Associate Director, Clinical Operations Cogent BiosciencesAssociate Director, Clinical OperationsWaltham, Massachusetts$185,000–$215,000 / yearThis role is ideal for someone who enjoys balancing operational detail with strategic program oversight—an individual who can independently lead complex global studies while also contributing to broader Clinical Operations strategy, portfolio planning, process improvement, and cross-functional decision-making. Reporting to the Senior Director, Head of Clinical Operations, this individual will function as both a hands-on study leader and a strategic clinical operations partner, helping drive execution and operational excellence across multiple stages of development.
Director Clinical Operations Aura BioSearchDirector Clinical OperationsBoston, MassachusettsThis leadership role involves managing oncology trials, overseeing day-to-day operations, and working closely with both internal teams and external partners in a fast-paced environment. This is a pivotal role for a seasoned professional to lead oncology clinical trials in a dynamic and innovative environment.
Senior Clinical Operations Contractor Entrada Therapeutics IncSenior Clinical Operations ContractorBoston, MARemoteWe are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families. We expect multiple clinical data readouts as we advance several DMD programs across the U.K., EU, and U.S. By year-end 2026, we anticipate four clinical-stage programs in our DMD franchise (ENTR-601-44, ENTR-601-45, ENTR-601-50, and ENTR-601-51).
Senior Clinical Operations Contractor Entrada Therapeutics Inc.Senior Clinical Operations ContractorBoston, MARemoteWe are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families. We expect multiple clinical data readouts as we advance several DMD programs across the U.K., EU, and U.S. By year-end 2026, we anticipate four clinical-stage programs in our DMD franchise (ENTR-601-44, ENTR-601-45, ENTR-601-50, and ENTR-601-51).
Senior Director, Clinical Operations Madrigal PharmaceuticalsSenior Director, Clinical OperationsWaltham, Pennsylvania$262,059–$306,732 / yearThe ideal candidate is an experienced clinical operations leader who thrives in a fast-paced organization and has demonstrated success leading global clinical development programs, developing high-performing teams, and driving execution across complex cross-functional initiatives. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process.
Senior Clinical Operations Contractor Entrada TherapeuticsSenior Clinical Operations ContractorBoston, MassachusettsRemoteWe are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families. We expect multiple clinical data readouts as we advance several DMD programs across the U.K., EU, and U.S. By year-end 2026, we anticipate four clinical-stage programs in our DMD franchise (ENTR-601-44, ENTR-601-45, ENTR-601-50, and ENTR-601-51).
Product Manager - Veeva Clinical Operations Veeva Systems IncProduct Manager - Veeva Clinical OperationsBoston, MA$75,000–$165,000 / yearWorking closely with cross-functional teams, you will help execute the product vision to unify clinical systems, streamline trial execution, and speed the delivery of new therapies to patients. As a Product Manager for Veeva Clinical Operations, you will drive core features and enhancements for key applications that are transforming how the life sciences industry runs clinical trials.
Senior Director, Clinical Operations Keros Therapeutics IncSenior Director, Clinical OperationsLexington, MA$253,000–$300,000 / yearWith a focus on developing differentiated product candidates that are designed to alter TGF- signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. As the leader of the cross-functional Clinical Program Team, the Senior Director Clinical Operations (SDCO) will lead the planning and execution strategy of assigned clinical trials to achieve overall program and corporate objectives.
Senior Manager, Clinical Business Operations Relay Therapeutics IncSenior Manager, Clinical Business OperationsCambridge, MA$124,000–$177,000 / yearYou will work with the clinical study leads and cross-functional teams to establish governance process, which may include joint oversight committees, with key clinical vendors to monitor service levels and key performance indicators and manage issue escalation and resolution. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology.
Senior Manager, Clinical Business Operations Relay Therapeutics, Inc.Senior Manager, Clinical Business OperationsCambridge, MA$124,000–$177,000 / yearYou will work with the clinical study leads and cross-functional teams to establish governance process, which may include joint oversight committees, with key clinical vendors to monitor service levels and key performance indicators and manage issue escalation and resolution. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology.
NewAssociate Director, Clinical Operations (Contract) Centessa Pharmaceuticals, LLCAssociate Director, Clinical Operations (Contract)Boston, MA$75–$110 / hourCentessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa's OX2R agonist portfolio includes additional clinical and preclinical-stage assets with potential utility across a broader range of neurological, neurodegenerative, and neuropsychiatric conditions.
NewAssociate Director, Clinical Operations Contract Centessa Pharmaceuticals PlcAssociate Director, Clinical Operations ContractBoston, MA$75–$110 / hourCentessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa''s OX2R agonist portfolio includes additional clinical and preclinical-stage assets with potential utility across a broader range of neurological, neurodegenerative, and neuropsychiatric conditions.