South San Francisco, CA30+ days ago
Experience with medical review of individual case reports (ICSRs), signal detection, cumulative safety assessments, and risk management planning Proven ability to move fluidly between strategic leadership and detailed execution, particularly in early-stage of first-in-function roles Track record of influencing development, regulatory, and portfolio decisions at senior and governance levels Experience managing and transitioning work from external consultants and vendors to internal teams A collaborative, ethical, and inclusive leadership style with the ability to inspire followership and alignment across functions Ability to travel domestically up to 10-15% for internal and external meetings This role follows a hybrid schedule, with an expectation to be onsite at our South San Francisco headquarters at least three days per week About Maze Therapeutics Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. Influence senior stakeholders across functions to align on safety strategy, risk tolerance, and development trade-offs Operational Excellence Oversee and directly engage in operational PV activities as needed, including close collaboration with external consultants supporting case processing and compliance Design and evolve a scalable PV operating model that transitions from external support to internal ownership over time Provide strategic direction for outsourced PV activities, including CROs, consultants, and vendors Anticipate operational or compliance risks and proactively implement solutions that protect patients and enable program success As a Senior Director, we also expect you to demonstrate the following Leadership Competencies: Communication and Influence Role models clear communication and open two-way conversations.