Senior Director, Toxicology Amylyx PharmaceuticalsSenior Director, ToxicologyCambridge, MARemote$269,000–$291,667 / yearDevelop and execute comprehensive nonclinical safety strategies to support clinical candidate selection, IND-enabling activities, regulatory submissions, and clinical development across multiple programs including small molecules, peptides, protein-based biologics, anti-sense oligonucleotides. This person will: Serve as a toxicology leader across a diverse and expanding pipeline spanning multiple therapeutic areas and drug modalities, shaping nonclinical safety strategy from discovery to IND-enabling and throughout clinical phases.
Associate Director, Toxicology (Nonclinical Safety Evaluation) City TherapeuticsAssociate Director, Toxicology (Nonclinical Safety Evaluation)Cambridge, Massachusetts$174,000–$196,000 / yearThe Ideal Candidate • PhD or DVM, or equivalent advanced degree in Toxicology, Pharmacology, Pathology, Veterinary Sciences, or a related field, with 5+ years, Masters with 7+ or a Bachelors with 10+ of relevant experience in biotech or pharmaceutical drug development, or direct experience as a Study Director at a GLP-qualified CRO.• Strong experience overseeing outsourced nonclinical safety studies and critically reviewing protocols, data, and final reports.• The Role We’re seeking an Associate Director, Nonclinical Safety Evaluation (NSE) who will play a pivotal role in overseeing and critically evaluating nonclinical safety studies across City’s RNAi therapeutic programs.
Senior Director, Toxicology Amylyx Pharmaceuticals IncSenior Director, ToxicologyCambridge, MARemote$269,000–$291,667 / yearDevelop and execute comprehensive nonclinical safety strategies to support clinical candidate selection, IND-enabling activities, regulatory submissions, and clinical development across multiple programs including small molecules, peptides, protein-based biologics, anti-sense oligonucleotides. This person will: Serve as a toxicology leader across a diverse and expanding pipeline spanning multiple therapeutic areas and drug modalities, shaping nonclinical safety strategy from discovery to IND-enabling and throughout clinical phases.
Vice President Toxicology Alnylam Pharmaceuticals IncVice President ToxicologyMAStrong ability to interpret and integrate complex datasets across multiple disciplines, including pharmacology, DMPK, toxicology, and pathology, with a focus on assessing clinical relevance and impact. Lead and manage nonclinical studies and programs across a portfolio of projects, conducted internally and through CRO partners, either directly or through direct reports.
Nonclinical Toxicology Study Monitoring Scientist Vertex PharmaceuticalsNonclinical Toxicology Study Monitoring ScientistBoston, MassachusettsRemoteThis role is best suited for a scientifically grounded, highly organized, collaborative study monitor who thrives in a fast-paced environment, excels at managing multiple studies and competing priorities simultaneously , and communicates clearly and succinctly to drive study execution and decision-making. We are seeking a Nonclinical Toxicology Study Monitoring Scientist to play a critical role in supporting the safety assessment of both large and small molecule modalities including cell and gene therapies across the development pipeline by providing scientific, technical, and operational oversight of outsourced nonclinical studies.
Director/Senior Director, Nonclinical Safety (Toxicology) Nimbus TherapeuticsDirector/Senior Director, Nonclinical Safety (Toxicology)Boston, MA$225,000–$285,000 / yearManage nonclinical safety studies conducted by CROs with efficient governance including contract execution, authorization of study amendments, schedule and budget variance management, progress reporting to stakeholders, review of data and draft study reports, completion of contract milestones, study close-out and alignment of nonclinical safety evaluations with drug development efforts and priorities. Collaborate with CMC, Program & Portfolio Management, Clinical, Medical, and Regulatory Affairs to develop program-specific strategies for appropriate data generation in support of development candidate nomination, IND/CTA filing, and clinical development of new small molecule drug entities.
Toxicology Research Scientist Vertex PharmaceuticalsToxicology Research ScientistBoston, MassachusettsWork within a close-knit team, this individual will leverage advanced in vitro technologies, laboratory automation, and computational approaches to design, execute, analyze, and derive insights from mechanistic and phenotypic screening assays designed to evaluate the safety of new candidate molecules. The individual will work closely with cross-functional colleagues across Preclinical Sciences, Medicinal Chemistry, Data and Computational Sciences, Data Technology and Engineering, and Research with the shared goal of advancing the Vertex portfolio.
Associate Director / Director, Toxicology Beam Therapeutics IncAssociate Director / Director, ToxicologyCambridge, MA$185,000–$260,000 / yearBeam's suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. Provide toxicology support for regulatory submissions and interactions with health authorities, including the authoring of nonclinical safety sections of US and international regulatory applications, and help resolve nonclinical safety queries.
Associate Director, Toxicology Parabilis MedicinesAssociate Director, ToxicologyCambridge, MA$170,000–$210,000 / yearParabilis Medicines is seeking a highly motivated and driven Associate Director, Toxicology to lead nonclinical safety programs across a diverse pipeline built on Parabilis' clinically validated Helicon pipeline. The successful candidate will serve as the nonclinical safety lead on cross-functional project teams, working autonomously to define strategy, drive execution, influence candidate selection, and ensure robust safety assessment across our pipeline.
Associate Director, Translational Toxicology, Preclinical Development Wave Life Sciences LtdAssociate Director, Translational Toxicology, Preclinical DevelopmentLexington, MA$170,000–$230,000 / yearOur diversified pipeline is focused on our obesity, alpha-1 antitrypsin deficiency and PNPLA3 I148M liver disease programs and includes clinical programs for Duchenne muscular dystrophy and Huntington's disease, as well as several preclinical programs utilizing our versatile RNA medicines platform. Design toxicity studies: coordinate with Preclinical Outsourcing for placement and monitoring of the studies as well as the Bioanalytical and DMPK groups regarding integration of bioanalysis and toxicokinetic aspects into these studies to ensure on-time delivery of key data and study reports.
NewLCMS Toxicology Technologist Lighthouse Lab ServicesLCMS Toxicology TechnologistBrockton, MA$36–$40 / hourThis allows the on-site technologist to focus primarily on specimen preparation, instrument operation, quality control, and day-to-day laboratory workflow rather than spending time reviewing chromatograms or interpreting patient results. Our recruiting team has over 22 years of proven success placing job seekers in positions ranging from entry level Medical Technologists to seasoned Laboratory Directors.
Associate Director / Director, Toxicology Beam TherapeuticsAssociate Director / Director, ToxicologyCambridge, MA$185,000–$260,000 / yearBeam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. Provide toxicology support for regulatory submissions and interactions with health authorities, including the authoring of nonclinical safety sections of US and international regulatory applications, and help resolve nonclinical safety queries.
Director/Senior Director, Nonclinical Safety Toxicology Nimbus Therapeutics LLCDirector/Senior Director, Nonclinical Safety ToxicologyBoston, MA$225,000–$285,000 / yearManage nonclinical safety studies conducted by CROs with efficient governance including contract execution, authorization of study amendments, schedule and budget variance management, progress reporting to stakeholders, review of data and draft study reports, completion of contract milestones, study close-out and alignment of nonclinical safety evaluations with drug development efforts and priorities. Collaborate with CMC, Program & Portfolio Management, Clinical, Medical, and Regulatory Affairs to develop program-specific strategies for appropriate data generation in support of development candidate nomination, IND/CTA filing, and clinical development of new small molecule drug entities.
Senior Director, Toxicology Disc Medicine IncSenior Director, Toxicologymassachusetts, MA$261,000–$319,000 / yearReporting directly to the Vice President, Head of Toxicology, the successful candidate will play a pivotal role in leading nonclinical safety assessments and driving toxicology strategy across the Disc portfolio. The ideal candidate will also blend deep technical knowledge in nonclinical safety and pharmacokinetics with strong communication skills to cross-functionally guide programs toward clinical success.
Manager, Global Toxicology and Biocompatibility Boston Scientific CorpManager, Global Toxicology and BiocompatibilityMarlborough, MAAbout the role: Global Toxicology and Biocompatibility plays a critical role in medical device development at Boston Scientific, ensuring patient safety while enabling early product development decisions, supporting product design direction, enabling product approvals, and supporting market launch for product commercialization. The anticipated compensation listed above and the value of core and optional employee benefits offered by Boston Scientific (BSC) - see www.bscbenefitsconnect.com-will vary based on actual location of the position and other pertinent factors considered in determining actual compensation for the role.
Senior Director -Project Toxicologist - Clinical Pharmacology and Safety Sciences (Boston or Gaithersburg) AstraZeneca PlcSenior Director -Project Toxicologist - Clinical Pharmacology and Safety Sciences (Boston or Gaithersburg)Boston, MA$227,602–$341,404 / yearExtensive experience working as a Project Toxicologist across different therapy areas within the pharmaceutical/biotech project environment delivering pre-clinical toxicology packages and successful marketing for a range of modalities which should include small molecules, peptides and oligonucleotides. We value kindness alongside ambition, giving you the trust, tools, and cross-functional partnerships to lead with confidence and shape studies that matter-so your decisions today translate into meaningful patient impact tomorrow.
Associate Director, Program Toxicologist, Translational Medicine and Nonclinical Development BlueRock Therapeutics LPAssociate Director, Program Toxicologist, Translational Medicine and Nonclinical DevelopmentMassachusettsBlueRock Therapeutics, a wholly-owned and independently operated subsidiary of Bayer AG, is a leading engineered cell therapy company using its unique CELL+GENE platform to direct cellular differentiation and genetically engineer cells to create a new generation of cellular medicines that address large patient populations suffering from neurological, cardiovascular, and immunology diseases. Founded in 2016 to capitalize on these technological breakthroughs, we are advancing our novel CELL+GENE platform to develop, manufacture, and deliver an entirely new generation of authentic and engineered cell therapies across three therapeutic areas: neurology, cardiology, and immunology.
Senior Principal Toxicologist Keurig Dr Pepper IncSenior Principal ToxicologistBurlington, MA$130,700–$190,000 / yearThis role works side-by-side with Quality, Nutrition, Chemistry, Regulatory and Legal and plays a key role in the product development process of all our food and beverage categories through application of toxicology science, consumption data and risk assessment. Company Overview: Keurig Dr Pepper (Nasdaq: KDP) is a leading beverage company with more than 150 owned, licensed and partner brands that meet a wide range of needs and occasions.
Toxicologist Watton hallToxicologistCambridge, MassachusettsThis position requires a deep understanding of toxicological principles, regulatory requirements, and the ability to interpret complex data to inform decision-making. Analyze data from non-clinical studies to identify potential safety concerns and recommend strategies for risk mitigation.
Project Toxicologist, Director - Oncology Targeted Delivery (OTD) Safety Science, Clinical Pharmacology and Safety Sciences (Cambridge, MA or Gaithersburg, MD) AstraZeneca PlcProject Toxicologist, Director - Oncology Targeted Delivery (OTD) Safety Science, Clinical Pharmacology and Safety Sciences (Cambridge, MA or Gaithersburg, MD)Cambridge, MA$184,538–$276,808 / yearAlternative experience pathway: Candidates with a minimum bachelor's degree and substantial additional pharmaceutical industry experience may also be considered, including candidates with approximately 15 or more years of relevant experience. Professional experience: Typically, at least 10 years of experience in project toxicology, investigative toxicology, regulatory toxicology, or related safety-focused roles within the pharmaceutical, biotechnology, or CRO sector.