SFO AIRPORT SECURITY SCREENER - $31.11 PER HOUR CovenantSFO AIRPORT SECURITY SCREENER - $31.11 PER HOURSan Francisco, CA$31.11Screeners will use diverse, cutting edge electronic detection and imaging equipment to identify dangerous objects in baggage, cargo, and on passengers, preventing those objects from being transported onto aircraft. Transportation Security Officers provide security and protection of air travelers, airports, and aircraft in a courteous and professional manner.
Armed Security Officer - Oakland - Weekends part-time - $65 hour Metro One LPSG IncArmed Security Officer - Oakland - Weekends part-time - $65 hourOakland, CAWe are proud to provide top-tier security and loss prevention services to our valued clients, and we're growing fast! If you're looking for more than just a job - if you want to be part of a growing, supportive team where your hard work matters - M1 Global is your next career move.
NewWeekend Physical Security Officer - San Francisco 8 AM - 4 PM (Part Time) The Gap IncWeekend Physical Security Officer - San Francisco 8 AM - 4 PM (Part Time)San Francisco, CA$24–$29.40 / hourThis role blends premium hospitality with disciplined physical security practices, including perimeter protection, access control, emergency response, and real-time coordination with the Global Security Operations Center (GSOC). Sound Judgment & Decision-Making: Proven ability to assess situations quickly and make appropriate decisions during both routine activities and high-stress incidents, while remaining calm and composed.
Security Officer - weekends Mass General BrighamSecurity Officer - weekendsBelmont, CaliforniaThe framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission.
RN - Part-Time Weekend PACS Group IncRN - Part-Time WeekendCADevelop and maintain a good working rapport with inter-department personnel, as well as other departments within the facility to ensure that nursing services and activities can be adequately maintained to meet the needs of the residents. • Assist the Director and/or Infection Control Coordinator in identifying, evaluating, and classifying routine and jobrelated functions to ensure that tasks in which there is potential exposure to blood/body fluids are properly identified and recorded.
Security Charter Screener Agent (Part-Time) - SFO Unifi Security Pacific, Inc.Security Charter Screener Agent (Part-Time) - SFOSan Francisco, CAPart timeScreen passengers, vendors, and employees prior to aircraft boarding, including random body scans, bag checks, and Explosive Trace Detection (ETD) tests. · Must be able to constantly lift, move up, push, pull up to 70 lbs; and constantly walk, stand, reach above shoulder, climb, crawl, stoop, squat, kneel, & bend.
Security Officer (Part-Time) Four Seasons Hotels and ResortsSecurity Officer (Part-Time)San Francisco, CAShare duties in Security Operations Center with emergency and department phone monitoring, closed circuit television monitoring, alarm monitoring, vendor/solicitor/visitor access, and key control. The Security Department promotes and maintains every aspect of the property's physical security and safety for Guests, Residents, Employees, Assets, and Reputation 24-hours a day.
Retail Security Officer - Part Time/Extra Help/Continuous Recruitment RONIN PROTECTION SOLUTIONS INCRetail Security Officer - Part Time/Extra Help/Continuous RecruitmentHayward, CAThis role involves safeguarding a Cannabis retail environment by protecting employees, customers, and property while maintaining a welcoming and professional presence. Theft Prevention & Loss Prevention: Identify suspicious behavior, monitor CCTV when applicable, and take appropriate action to reduce shrinkage.
Security Officer - Facility (Part Time)(U) Legends GlobalSecurity Officer - Facility (Part Time)(U)Oakland, CaliforniaInteracts with guests, vendors and employees in a courteous and professional manner and complies with all legal and ethical instructions given by the Security Management team. Complete all assigned tasks within the guidelines & deadlines set by the Facility Security Supervisors on duty, Facility Security Manager, Security Manager, or the Sr.
Security Charter Screener Supervisor - SFO Unifi Security Pacific, Inc.Security Charter Screener Supervisor - SFOSan Francisco, CAPart timeScreen passengers, vendors, and employees prior to aircraft boarding, including random body scans, bag checks, and Explosive Trace Detection (ETD) tests. This role supervises access control operations, monitors passenger and vendor screening activities, and ensures consistent enforcement of security protocols.
Physician – Women's & Metabolic Health (Weekends) Maven Clinic 1099 Provider NetworkPhysician – Women's & Metabolic Health (Weekends)San Francisco, CA$115–$175 / hourAs part of our MVP launch team, you will deliver high-quality virtual care across a broad spectrum of needs — from contraception and menopause management to metabolic and weight-related care — while contributing to the development of our clinical protocols and digital care model. Maven's award-winning digital programs provide clinical, emotional, and financial support all in one platform, spanning fertility & family building, maternity & newborn care, parenting & pediatrics, and menopause.
Security Employee Screener - SFO Unifi Security Pacific, Inc.Security Employee Screener - SFOSan Francisco, CAFull timeResponsible for overseeing all aspects of provisioning and access control management for all individuals, including employees, visitors, contractors, and vendors—accessing client facilities. · Must be able to constantly lift, move up, push, pull up to 70 lbs; and constantly walk, stand, reach above shoulder, climb, crawl, stoop, squat, kneel, & bend.
Security Cargo Employee Screener - SFO Unifi Security Pacific, Inc.Security Cargo Employee Screener - SFOSan Francisco, CAFull timeResponsible for overseeing all aspects of provisioning and access control management for all individuals, including employees, visitors, contractors, and vendors—accessing client facilities. · Must be able to constantly lift, move up, push, pull up to 70 lbs; and constantly walk, stand, reach above shoulder, climb, crawl, stoop, squat, kneel, & bend.
Security Employee Screener Supervisor - SFO Unifi Security Pacific, Inc.Security Employee Screener Supervisor - SFOSan Francisco, CAFull timeResponsible for overseeing all aspects of provisioning and access control management for all individuals, including employees, visitors, contractors, and vendors-accessing client facilities. · Must be able to constantly lift, move up, push, pull up to 70 lbs; and constantly walk, stand, reach above shoulder, climb, crawl, stoop, squat, kneel, & bend.
Security Employee Lead Screener - SFO Unifi Security Pacific, Inc.Security Employee Lead Screener - SFOSan Francisco, CAFull timeMust be able to frequently lift, greater than 70lbs and constantly lift up to 70 lbs; Constantly push, pull up to 70 lbs; and constantly walk, stand for long periods, reach above shoulder, climb, crawl, stoop, squat, kneel, & bend. Responsible for overseeing all aspects of provisioning and access control management for all individuals, including employees, visitors, contractors, and vendors—accessing client facilities.
Desk Clerk - 1296 Shotwell (Part Time Weekend Graveyard) Chinatown Community Development CenterDesk Clerk - 1296 Shotwell (Part Time Weekend Graveyard)San Francisco, CAPart timeWe own and/or manage approximately 30 affordable housing buildings serving over 3,800 low-income seniors, single adults, formerly homeless adults, and families of diverse ethnic and cultural backgrounds in San Francisco’s Chinatown, Tenderloin, Western Addition, and Polk Gulch neighborhoods. Take initiative in calling 911 or non-emergency police per protocol and report all building emergencies to the On Site Manager, Property Manager and/or Property Supervisor.
Desk Clerk - Transbay 2 West ( Part Time Weekend Swing) Chinatown Community Development CenterDesk Clerk - Transbay 2 West ( Part Time Weekend Swing)San Francisco, CAPart timeWe own and/or manage approximately 30 affordable housing buildings serving over 3,800 low-income seniors, single adults, formerly homeless adults, and families of diverse ethnic and cultural backgrounds in San Francisco’s Chinatown, Tenderloin, Western Addition, and Polk Gulch neighborhoods. Take initiative in calling 911 or non-emergency police per protocol and report all building emergencies to the On Site Manager, Property Manager and/or Property Supervisor.
Desk Clerk - Broadway Sansome (Part Time Weekend Graveyard) Chinatown Community Development CenterDesk Clerk - Broadway Sansome (Part Time Weekend Graveyard)San Francisco, CAPart timeWe own and/or manage approximately 30 affordable housing buildings serving over 3,800 low-income seniors, single adults, formerly homeless adults, and families of diverse ethnic and cultural backgrounds in San Francisco’s Chinatown, Tenderloin, Western Addition, and Polk Gulch neighborhoods. Take initiative in calling 911 or non-emergency police per protocol and report all building emergencies to the On Site Manager, Property Manager and/or Property Supervisor.
NewSecurity Dispatcher/Office Admin - Part Time The Guard AllianceSecurity Dispatcher/Office Admin - Part TimeConcord, CaliforniaThe responsibilities of the Security Dispatcher/Administrator position include, but are not limited to, the following: Perform a wide variety of administrative duties and related work as assigned. With strong leadership, we promote an atmosphere of mutual respect and teamwork where member efforts are always acknowledged.
Facility Security Assistant, PT (Continuous) City of Oakland, CaliforniaFacility Security Assistant, PT (Continuous)Oakland, CA$30.13–$37.01 / hourUnder immediate supervision in the Office of Parks and Recreation, Facility Security Assistants provide support related to the use and security of public buildings, recreational facilities, parks, and other City properties in use by staff or patrons; perform a combination of building security, answering phones, responding to the public, accepting rental applications and modifying rental agreements for extended hours, enforcing rules and regulations of the facility, moving and setting-up furniture which may include lifting and other light cleaning duties; and perform related duties as assigned. With an emphasis on Oakland's youth, Oakland Parks, Recreation & Youth Development (OPRYD), and its partners will provide best-in-class, relevant, and equitable programs and services, while meeting the specific needs of people and communities both at the neighborhood level and regionally throughout the City of Oakland.
Security Officer (Flex) SurefoxSecurity Officer (Flex)San Francisco, CaliforniaWe are currently seeking experienced (part time) Security Officers with high integrity and professionalism with the ability to work, when called upon, in multiple Surefox locations servicing a variety of different clients. Security Officers must be highly motivated Security Professionals who possess the ability to work at multiple Surefox locations with minimal training and supervision.
Restaurant Team Member, Weekend Shift - Unit 1547 Whataburger RestaurantsRestaurant Team Member, Weekend Shift - Unit 1547Pleasant Hill, CaliforniaFrom retirees and teens working part-time to entry-level careers to experienced professionals ready to work full time, we’re just a click away from serving up a good day! High school diploma/GED, equivalent work experience, or is attending high school, or educational equivalent, e.g., home school or primary vocational programs.
Flex Security Agent SurefoxFlex Security AgentSan Francisco, CaliforniaWork Location: San Francisco & Menlo Park What You Will Do: Support staffing requirements at multiple Surefox locations during shortages due to vacations, call-offs, no shows, suspensions, holidays, or other program needs. Support and staff various positions, including, but not limited to the following job positions, as required: Resilience Officer, Incident Commander, Mobile Residential Security Agent, Residential Security.
Security Engineer II, Detection and Response Circle Internet Financial LLCSecurity Engineer II, Detection and ResponseSan Francisco, CARemote$122,500–$165,000 / yearCircle's platform includes the world's largest regulated stablecoin network anchored by USDC, Circle Payments Network for global money movement, and Arc, an enterprise-grade blockchain designed to become the Economic OS for the internet. Hands-on experience using AI tooling both to accelerate work and to address threats, coupled with a strong understanding of the organizational risks AI introduces and strategies to defend against them.
RN, Hospice, Nights & Weekends Sutter HealthRN, Hospice, Nights & WeekendsAlameda, CA$64.16–$86.22 / hourEmployees of Sutter Health and its entities may handle hazardous drugs in the course of their work, including patient care, which requires them to manage, store, prepare, receive, unpack, transport, dispose of, or administer drugs identified as hazardous or potentially hazardous by the National Institute for Occupational Safety and Health (NIOSH) and in accordance with the USP 800 guidelines. Total compensation considers multiple factors, including, but not limited to a candidate's experience, education, skills, licensure, certifications, departmental equity, training, and organizational needs.
Security Officer EMT Chenega Security California CorpSecurity Officer EMTBerkeley, CaliforniaPart timePossess and maintain a valid California Security Guard Registration ("Guard Card") issued by the California Bureau of Security and Investigative Services (BSIS). As a Security Officer/EMT , you will play a vital role in protecting people, property, and critical assets while serving as a first responder during emergencies.
Security Officer Four Seasons Hotels and ResortsSecurity OfficerSan Francisco, CANew to the Four Seasons portfolio and new to the City of San Francisco, this stand alone residence contains 146 private residences that have wowed many with their spacious living and distinctive elegance. Share duties in Security Operations Center with emergency and department phone monitoring, closed circuit television monitoring, alarm monitoring, vendor/solicitor/visitor access, and key control.
Electronic Security IT System Administrator (System Administrator 2) - Fremont, CA M.C. Dean IncElectronic Security IT System Administrator (System Administrator 2) - Fremont, CAFremont, CA$99,680–$149,520 / yearAs part of (SES) Strategic Business Unit you will be part of a team that designs, engineers, integrates, operates and maintains electronic security services inclusive of intrusion detection, access control, biometric authentication, video surveillance, audio visual, it systems, perimeter defense and command and control systems for federal, local and commercial customers across high-growth markets. Certifications in Windows (10, 11, Server 2016-2025), AWS Cloud, Linux (Red Hat, Centos, Docker, Kubernetes), Databases (SQL, Cassandra, Mongo, Redis), and Networking Protocols strongly preferred.
Electronic Security IT System Administrator (System Administrator 3)- Fremont, CA M.C. Dean, IncElectronic Security IT System Administrator (System Administrator 3)- Fremont, CAFremont , California$114,640–$157,630 / yearFull timeAs part of (SES) Strategic Business Unit you will be part of a team that designs, engineers, integrates, operates and maintains electronic security services inclusive of intrusion detection, access control, biometric authentication, video surveillance, audio visual, it systems, perimeter defense and command and control systems for federal, local and commercial customers across high-growth markets. Certifications in Windows (10, 11, Server 2016-2025), AWS Cloud, Linux (Red Hat, Centos, Docker, Kubernetes), Databases (SQL, Cassandra, Mongo, Redis), and Networking Protocols strongly preferred.
Security Manager SP Plus CorporationSecurity ManagerSAN FRANCISCO, CA$110,000–$129,000 / yearManage the day-to-day activities of the assigned locations including: appropriate customer interactions, supervising the completion of all security assignments, submitting reports and investigations, scheduling and assigning security staff to daily posts, monitoring employee rest breaks and meal periods, Overseeing the security personnel (e.g. Manage the day-to-day activities of the assigned location ensuring that security operations are handled within contractual guidelines of the specific location, fostering good client relations and promoting a professional and safe image and approach to the business.
Security Manager Metropolis TechnologiesSecurity ManagerSAN FRANCISCO, California$110,000–$129,000 / yearFull timeManage the day-to-day activities of the assigned locations including: appropriate customer interactions, supervising the completion of all security assignments, submitting reports and investigations, scheduling and assigning security staff to daily posts, monitoring employee rest breaks and meal periods, Overseeing the security personnel (e.g. Responsibilities: Manage the day-to-day activities of the assigned location ensuring that security operations are handled within contractual guidelines of the specific location, fostering good client relations and promoting a professional and safe image and approach to the business.
Security Officer II Sutter HealthSecurity Officer IINovato, CA$27.84–$36.18 / hourEMERGENT SITUATIONS: Responds to all emergency calls for assistance to control: disorderly conduct or combative patients, potential and/or actual infant or child patient abductions, bomb threats or reports of suspicious packages, evacuation incidents, and/or chemical spills, for crowd control purposes. SKILLS AND KNOWLEDGE: General knowledge of the usual duty requirements of a security officer with an emphasis on the physical and emotional maturity required for the high degree of judgment and diplomacy necessary to work efficiently in a healthcare environment.
NewSecurity Officer Lead Sutter HealthSecurity Officer LeadSan Francisco, CA$35.13–$49.17 / hourSKILLS AND KNOWLEDGE: General knowledge of the usual duty requirements of a security officer with an emphasis on the physical and emotional maturity required for the high degree of judgment and diplomacy necessary to work efficiently in a healthcare environment. Total compensation considers multiple factors, including, but not limited to a candidate's experience, education, skills, licensure, certifications, departmental equity, training, and organizational needs.
Corporate Security Agent (CCW) SurefoxCorporate Security Agent (CCW)San Francisco, CaliforniaTechnical Certifications: Formal TECC/TCCC (Tactical Casualty Care) certifications, NREMT licensure, or experience with advanced tactical medical integration. Monitor camera feeds, Video Management Systems (VMS), and Access Control Systems (ACS) to identify and neutralize threats before they escalate.
Residential Security Agent SurefoxResidential Security AgentSan Francisco, CaliforniaWe are looking for someone who has Extensive background in either Military, Security or Law Enforcement, exceptional observational skills and pays close attention to detail, someone who works independently on assignments and has the ability to liaise and coordinate with supporting or adjacent teams, agencies, or vendors to ensure clients’ security requirements are met in a timely and professional manner. Other responsibilities include, but are not limited to responding to emergency events, medical & non-medical issues, incident detection, observation, physical security, overwatch and reconnaissance to assigned clients, staffing deficiencies, and handling client requests in a timely manner.
Corporate Security Agent SurefoxCorporate Security AgentSan Francisco, CaliforniaTechnical Certifications: Formal TECC/TCCC (Tactical Casualty Care) certifications, NREMT licensure, or experience with advanced tactical medical integration. Monitor camera feeds, Video Management Systems (VMS), and Access Control Systems (ACS) to identify and neutralize threats before they escalate.
Executive Protection and Residential Security Agent SurefoxExecutive Protection and Residential Security AgentSan Francisco, CaliforniaWe are looking for someone who has exceptional observational skills and pays close attention to detail, someone who works independently on assignments and has the ability to liaise and coordinate with supporting or adjacent teams, agencies, or vendors to ensure clients’ security requirements are met in a timely and professional manner. Other responsibilities include, but are not limited to responding to emergency events, medical & non-medical issues, incident detection, observation, physical security, overwatch and reconnaissance to assigned clients, staffing deficiencies, and handling client requests in a timely manner.
security officer II Sutter Healthsecurity officer IISan Francisco, CA$27.84–$36.18 / hourSKILLS AND KNOWLEDGE: General knowledge of the usual duty requirements of a security officer with an emphasis on the physical and emotional maturity required for the high degree of judgment and diplomacy necessary to work efficiently in a healthcare environment. Total compensation considers multiple factors, including, but not limited to a candidate's experience, education, skills, licensure, certifications, departmental equity, training, and organizational needs.
Security Officer - Flexible Schedule GardaWorld Security Services U.S.Security Officer - Flexible ScheduleSan Bruno, CA$20–$22 / hourAs a Security Officer – Concierge, there is a high focus on customer service since you will be working with people on all shifts, in environments such as office towers, hotels, shopping centers, etc. GardaWorld Security is a global champion in sophisticated and tailored security solutions, employing and training highly skilled and dedicated professionals across the globe.
Security Officer - Special Response GardaWorld Security Services U.S.Security Officer - Special ResponseDaly City, CA$20–$21 / hourGardaWorld Security is a global champion in sophisticated and tailored security solutions, employing and training highly skilled and dedicated professionals across the globe. As a Security Officer – Surveillance, you will be the person spotting threats before they escalate in environments such as a security operations centers, call centers, parking gatehouses, etc.
Premier Security Flex Officer GardaWorld Security Services U.S.Premier Security Flex OfficerNicasio, CA$21–$30 / hourGardaWorld Security is a global champion in sophisticated and tailored security solutions, employing and training highly skilled and dedicated professionals across the globe. As a Security Officer – Surveillance, you will be the person spotting threats before they escalate in environments such as a security operations centers, call centers, parking gatehouses, etc.
Asset Protection Security Guard, San Francisco Union Square - Flex Macy's IncAsset Protection Security Guard, San Francisco Union Square - FlexSan Francisco, CAWhether you're helping a customer find the perfect gift, streamlining operations in one of our distribution centers, enhancing our online shopping experience, buying in-style and on-trend merchandise to outfit our customers, or designing a balloon for the Thanksgiving Day Parade, we offer unique opportunities to be part of some of the most memorable moments in people's lives. The Visual Security Officer is an entry-level opportunity within Asset Protection with the primary responsibilities of communicating suspicious activity to Asset Protection detectives and management, maintaining a safe business environment, and providing strong customer service.
Security Field Supervisor GardaworldSecurity Field SupervisorEmeryville, CAGardaWorld Security is a global champion in sophisticated and tailored security solutions, employing and training highly skilled and dedicated professionals across the globe, offering a wealth of opportunities to individuals looking to gain experience and develop professionally in a growing industry. As the Field Services Supervisor in Emeryville, CA you'll be the vital link between our organization and our customers, ensuring top-tier customer service and representing GardaWorld as the industry's premier provider of contract security services.
Senior Engineer - Security Products Backend APIs Fastly IncSenior Engineer - Security Products Backend APIsSan Francisco, CA$181,220–$217,464 / yearFastly's edge cloud platform enables customers to create great digital experiences quickly, securely, and reliably by processing, serving, and securing our customers' applications as close to their end-users as possible - at the edge of the Internet. If reasonable accommodation is needed to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please contact your Recruiter, or the Fastly Employee Relations team at candidateaccommodations@fastly.com or 501-287-4901.
Security Staff - The Fillmore Live Nation Entertainment IncSecurity Staff - The FillmoreSan Francisco, CA$19.18–$20 / hourJob Summary: Role: Primary responsibility Assist in keeping the venue safe for guests by patrolling the premises, checking credentials at pass gates, monitoring barricade activity, searching guests for prohibited items, operating metal detectors, assisting the team with incidents, responding to emergencies and assisting the operations team with crowd management. Additional responsibility Perform other duties as assigned during concerts such as greeting patrons, scanning tickets and answering guest questions.
Security Officer (Temporary) Four Seasons Hotels and ResortsSecurity Officer (Temporary)San Francisco, CAFour Seasons Hotel San Francisco overlooks Yerba Buena Gardens and is located just steps away from the City's Financial District, Union Square shopping, the Moscone Convention Center, the Museum of Modern Art, and the Contemporary Jewish Museum, amid the city's finest cultural and dining venues. When you're not shopping at Union Square, enjoying the city's diverse culinary scene or exploring one of the Bay Area's top attractions, unwind in our newly renovated guest rooms, designed to represent the natural beauty of San Francisco's fog, redwood trees and ocean.
Corporate Security Agent- EMT Cert Required Crisis24Corporate Security Agent- EMT Cert RequiredSan Francisco, CAFull timePartner with various intelligence and investigations teams, global security operations center assets, other private security firms, and local law enforcement to proactively identify and mitigate threats. Job Type: Full-time Information Security Protect the data and systems of Crisis24 and its stakeholders by adhering to policies, reporting incidents and potential problems, completing regular training, and identifying opportunities for improvement.
Senior Manager, Engineering - Platform Security Fastly IncSenior Manager, Engineering - Platform SecuritySan Francisco, CA$228,280–$273,936 / yearFastly's edge cloud platform enables customers to create great digital experiences quickly, securely, and reliably by processing, serving, and securing our customers' applications as close to their end-users as possible - at the edge of the Internet. If reasonable accommodation is needed to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please contact your Recruiter, or the Fastly Employee Relations team at candidateaccommodations@fastly.com or 501-287-4901.
Senior Security Engineer I, Advanced Response CoreWeave IncSenior Security Engineer I, Advanced ResponseCA$139,000–$204,000 / yearTo conform to U.S. Government export regulations applicable to that information, applicant must either be (A) a U.S. person, defined as a (i) U.S. citizen or national, (ii) U.S. lawful permanent resident (green card holder), (iii) refugee under 8 U.S.C. § 1157, or (iv) asylee under 8 U.S.C. § 1158, (B) eligible to access the export controlled information without a required export authorization, or (C) eligible and reasonably likely to obtain the required export authorization from the applicable U.S. government agency. Running a structured threat hunting program informed by operationalized intelligence turning actor profiles, campaign reporting, and TTP gaps into hunts, and turning hunt findings into durable actions to harden CoreWeave and improve our response posture.
Security Officer I (Saturday - Tuesday, 6:30 am - 5:00 pm shift) Penumbra IncSecurity Officer I (Saturday - Tuesday, 6:30 am - 5:00 pm shift)Alameda, CA$22–$30 / hourIndividual compensation will vary based on factors such as qualifications, skill level, competencies, work location and shift, and will increase over time based on meeting performance and business needs. Penumbra designs, develops, manufactures, and markets novel products and has a broad portfolio that addresses challenging medical conditions in markets with significant unmet need.