Project Management & Strategic Operations Associate Director Vertex Pharmaceuticals IncProject Management & Strategic Operations Associate DirectorBoston, MA$155,700–$233,500 / yearBy collaborating closely with Project Leaders, cross-functional Project Team members, and contract research partners, the incumbent develops and maintains fully integrated project plans to ensure that deliverables are successfully executed, are in accordance with project and disease area objectives, and are within budget. General Summary: The Associate Director, Preclinical Sciences, Program Management and Strategic Operations, will be responsible for the integration, creation, and execution of multiple complex pharmaceutical development/regulatory plans.
Lab Automation Engineer Vertex Pharmaceuticals IncLab Automation EngineerBoston, MA$85,600–$128,400 / yearEducation and Experience: Typically requires a Bachelor's Degree in chemical engineering, computer sciences or related field and 1 years experience in life sciences, engineering or academia. The Lab Automation Engineer will be a part of a team dedicated to designing, implementing, and validating automation solutions, across various automation platforms (Hamilton/Biomek/etc.), with a moderate degree of supervision.
Computational Genomics Senior Research Scientist Vertex Pharmaceuticals IncComputational Genomics Senior Research ScientistSan Diego, CA$129,900–$194,900 / yearWorking closely with cross-functional disease project teams, you will help shape the development of novel therapies in areas including lung diseases and pain by designing human genetic and genomics studies and translating complex datasets into insights that inform program strategy, target evaluation, biomarker development, and mechanistic understanding. Minimum Qualifications: PhD in computational biology, bioinformatics, genomics, human genetics, systems biology, bioengineering, or a related field, with 3+ years of relevant post-doctoral or industry experience; or Master's degree in a related field with 8+ years of relevant industry experience.
Computational Chemistry Principal Research Scientist (Computational Drug Design) Vertex Pharmaceuticals IncComputational Chemistry Principal Research Scientist (Computational Drug Design)Boston, MA$144,800–$217,200 / yearThis individual will be responsible for contributing to both hit/lead identification and optimization programs using a broad range of computational approaches including molecular modeling, cheminformatics, data science, and AI-enabled methods. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Principal Engineer, Agentic AI Platform Integrations Vertex Pharmaceuticals IncPrincipal Engineer, Agentic AI Platform IntegrationsBoston, MA$166,640–$250,000 / yearVertex is seeking an Integrations Engineer, Agentic AI Platform to connect the AI/agentic platform to the systems, tools, and data sources that make AI valuable in real enterprise workflows. Enable AI workflows to interact reliably with core enterprise platforms such as collaboration tools, knowledge systems, workflow tools, and line-of-business applications.
Project Management & Strategic Operations Manager Vertex Pharmaceuticals IncProject Management & Strategic Operations ManagerBoston, MA$124,000–$186,000 / yearThe ideal candidate is a highly organized and agile operations professional who thrives in a fast-paced environment, can manage multiple priorities simultaneously, and is experienced in supporting change management initiatives and driving efficiencies across cross-functional teams. Experience working cross-functionally with teams such as Research Scientists, Preclinical Project Managers, Procurement, Legal, Contracting, Lab Operations, or Records Management.
Principal Analyst, G&A Technology Vertex Pharmaceuticals IncPrincipal Analyst, G&A TechnologyBoston, MA$142,800–$214,200 / yearThe ideal candidate combines deep expertise in technology delivery, stakeholder engagement, and cross-functional leadership with a proven track record of partnering with Legal, Compliance, and Corporate Communications organizations in complex, highly regulated environments. In this role, you will partner closely with stakeholders to deliver technology solutions that strengthen operations, enhance the user experience, and support strategic priorities across corporate functions, with a particular focus on Legal, Compliance and Corporate Communication needs.
Senior Principal AI Engineer, Agentic AI Platform & Control Tower Ops Vertex Pharmaceuticals IncSenior Principal AI Engineer, Agentic AI Platform & Control Tower OpsBoston, MA$188,000–$282,000 / yearIn addition to building out the core platform, this leader will own the vision for a centralized AI Control Tower / Control Plane / Gateway that enables agent monitoring, observability, policy enforcement, governance, and operational controls across AI solutions at Vertex. Demonstrated experience using AI-assisted software development and autonomous coding agents to design, generate, test, review, debug, optimize, and refactor code across complex enterprise systems.
Director, Compliance Business Partner Vertex Pharmaceuticals IncDirector, Compliance Business PartnerBoston, MA$200,000–$300,000 / yearExpert knowledge of statutes, regulations, and guidance documents applicable to commercial, development and medical affairs activities, including research and interpretation of the Food, Drug, and Cosmetic Act; FDA regulations and guidance; federal and state anti-kickback statutes; OIG guidance documents and advisory opinions; the False Claims Act; and the PhRMA Code and extensive experience providing legal counsel on these topics. The Business Partner must have strong, demonstrated knowledge of laws, regulations, and codes applicable to the pharmaceutical industry, including the US and international anti-bribery/anti-corruptions laws such as the Anti-Kickback Statute, False Claims Act, and Foreign Corrupt Practices Act and experience providing advice and counsel to biotechnology/pharmaceutical companies on these issues.
Principal Analyst, PPM Technology Vertex Pharmaceuticals IncPrincipal Analyst, PPM TechnologyBoston, MA$142,800–$214,200 / yearAdditionally, the Business Engagement & Technology Principal Analyst will maintain reliable, scalable and compliant systems that easily meet business needs by efficient delivery and enhancements that provides opportunities for developing and implementing innovative solutions and integrations. General Summary: The Business Engagement & Technology Principal Analyst will be a technical resource in ensuring delivery and support of commercial-off-the-shelf (COTS) and a wide range of custom solutions in support of their business partners.
Executive Director, Portfolio & Program Management Vertex Pharmaceuticals IncExecutive Director, Portfolio & Program ManagementBoston, MA$260,800–$391,200 / yearThe role is accountable for all program management efforts across the drug development lifecycle and commercialization, including Disease Area Strategy Teams (DST), Program Teams (PT), and research PTs, ensuring end-to-end integration with DST strategy for a subset of Vertex's portfolio diseases. This role drives organizational design, strategic growth, and operational excellence, with expanded scope to lead multiple disease areas and mentor senior program managers.
Associate Director, Manufacturing Process and Technical Quality Assurance Cell and Genetic Therapies - VCGT Vertex Pharmaceuticals IncAssociate Director, Manufacturing Process and Technical Quality Assurance Cell and Genetic Therapies - VCGTBoston, MA$156,600–$234,800 / yearGeneral Summary: The Manufacturing Process & Technical Quality Associate Director provides end-to-end l quality oversight for cell and gene therapy programs across clinical development, commercialization, product launch, and post-approval lifecycle management. Lead and/or support quality review of complex investigations, deviations, change controls, risk assessments, and compliance issues impacting product quality or manufacturing processes.
Snr Director, Quality CGT Personalized Medicine Vertex Pharmaceuticals IncSnr Director, Quality CGT Personalized MedicineBoston, MA$180,800–$271,200 / yearEstablish compliance governance routines to proactively monitor compliance trends, operational performance, and emerging risks that may impact product quality, patient safety, supply continuity, or program execution; lead or support risk-based mitigation plans, continuous improvement actions, and sustainable process enhancements. Provide strategic Quality Systems leadership in support of personalized medicine /advanced CGT programs, ensuring alignment with CGT Business Objectives, Vertex Global Quality Strategy, commercial priorities, regulatory expectations, and patient-centered outcomes.
Center Account Manager, Northwest (Cystic Fibrosis) Vertex Pharmaceuticals IncCenter Account Manager, Northwest (Cystic Fibrosis)California, CA$136,000–$204,000 / yearThe Center Account Manager (CAM) will be responsible for achieving and maximizing territory sales goals by developing a strategic business plan, communicating thorough disease and product knowledge to healthcare professional customers (HCP's), and utilizing effective and appropriate selling strategies. This role will work cross-functionally within the sales/marketing team and compliantly across the entire organization (Managed Markets, Specialty Pharmacy, Patient Services, Medical, HR, Legal, Regulatory and Compliance teams).
Director, Field Technology Vertex Pharmaceuticals IncDirector, Field TechnologyBoston, MA$185,900–$278,900 / yearKey Duties and Responsibilities: Partner closely with Business Units, Leadership Teams, Information Technology (DTE), Insights & Analytics, and IC & Sales Planning to lead CRM initiatives, innovation, processes, and new ways of working. Guide team prioritization, resource allocation, clear roles/responsibilities, and workload management/sustainability, mentoring and developing a high performing team equipped with clear processes and efficiency tools.
Associate Director, Clinical Study Quality Lead (Hybrid) Vertex Pharmaceuticals IncAssociate Director, Clinical Study Quality Lead (Hybrid)Boston, MA$160,600–$240,800 / yearOverall, the SQL is responsible for the development and execution of audit/quality plans, accurately identifying and communicating compliance risks and overseeing action plans to mitigate risks, real-time study inspection readiness oversight, and collaboratively identifying and driving inspection preparedness strategies and activities. Provides strategic, risk-based GCP quality compliance oversight of studies within assigned disease areas to drive compliance with regulatory requirements to ensure the protection of participants' safety, rights, and well-being as well as the integrity and credibility of study data generated.
Computational Genomics Research Scientist Vertex Pharmaceuticals IncComputational Genomics Research ScientistBoston, MA$112,000–$168,000 / yearThis Boston-based position is part of the global Data and Computational Sciences organization and will collaborate closely with research teams spanning stem cell biology, immunology, gene editing, and pre-clinical development to design studies, execute and analyze complex genomic analyses, and ultimately generate biological insights that drive early research across multiple disease programs. As an embedded computational scientist, you will be responsible for performing bulk and single-cell sequencing analyses, spatial transcriptomics, and multiomic profiling to help uncover the molecular programs that govern therapeutic cell identity, differentiation, function, and safety to accelerate the development of next-generation cell and gene therapies.
DTE Audit & Compliance Manager (Sr. Principal Analyst) Vertex Pharmaceuticals IncDTE Audit & Compliance Manager (Sr. Principal Analyst)Boston, MA$164,400–$246,600 / yearThis role serves as the primary liaison between operational teams and auditors, ensuring timely preparation, execution, response, and remediation of Internal Audits, GxP audits, and regulatory inspections. The role partners closely with Internal Audit, Quality Assurance, SOX PMO, system owners, and business teams to ensure audit commitments are met and compliance obligations are fulfilled.
Senior Medical Science Liaison - Pain (Georgia) Vertex Pharmaceuticals IncSenior Medical Science Liaison - Pain (Georgia)GA$171,300–$256,900 / yearThe Sr MSL serves as a scientific liaison to the medical/academic community and is responsible for establishing and maintaining relationships with (Allied) Health Care Providers/Professionals (HCPs) and other key stakeholders involved in healthcare decision making to ensure the appropriate dissemination of clinical, scientific, and health economic data with respect to pain and Vertex's compounds in a timely, ethical, and stakeholder-focused manner. Develops and fosters effective and trusting relationships with Thought Leaders and identifies and engages other appropriate (allied) HCPs and other stakeholders involved in clinical practice decision making with regards to managing conditions associated with pain, resulting in scientific engagement with a large network of stakeholders involved in affecting care of patients experiencing pain.
Supply Chain Coordinator (Contract) Vertex PharmaceuticalsSupply Chain Coordinator (Contract)Boston, Massachusetts$32–$34 / hourAgreeing to the Atrium Terms and Conditions, includes permission to use the email address and mobile phone number you provide during the application process or throughout the duration of your prospective or actual employment to notify you of job openings, profiles, articles, news, and other employment-related information, as well as to notify you of special promotions or additional products and services offered by us or our affiliates and partners. Activities typically consist of well-defined support tasks that are performed independently as well as projects of increased complexity completed under limited supervision.