7 12 · Blood Product Administration to ECMO Circuit: Administer blood products (e.g., packed red blood cells, platelets, fresh frozen plasma, cryoprecipitate) via the ECMO circuit to maintain target hemoglobin, platelet counts), and coagulation factors; monitor transfusion effects on circuit function and patient hematology; troubleshoot transfusion-related complications like hemolysis or clotting · Clot Formation Management: Evaluate clot formation through staging (e.g., visual inspection, pressure monitoring), triage severity, and recommend anticoagulation adjustments to mitigate risks of major patient events such as embolism or circuit failure, following ELSO and AmSECT guidelines for thrombosis prevention and management. · CVVHD/Hemodialysis Management (e.g., Prismaflex, NxStage, Aquadex): Assist in setup of continuous veno-venous hemodiafiltration (CVVHD) or hemodialysis devices integrated into the ECMO circuit; monitor therapy parameters including dialysate flow, ultrafiltration rates, electrolyte balance, and fluid removal; manage ongoing therapy by adjusting settings for optimal clearance and patient stability; troubleshoot issues such as filter clotting, pressure alarms, or access problems, following hospital guidelines for renal replacement therapy in ECMO patients.