Director, In vivo Expert, CVRI (Cardiovascular, Renal & Immunology) Bayer AGDirector, In vivo Expert, CVRI (Cardiovascular, Renal & Immunology)Boston, MA$174,400–$261,600 / yearThe primary responsibilities of the Director-In vivo Expert, CVRI (Cardiovascular, Renal & Immunology) are to: Design, supervise and lead the execution of rodent in vivo mechanistic and disease models to support target identification, therapeutic candidate characterization, and mechanism of action evaluations utilizing internal and external resources (CROs) efficiently; Responsible for leading multiple drug discovery programs, initiatives, or external collaborations in Research / Early Development (RED) CVRI from target identification through support of early clinical development; Works as an expert opinion in Target ID teams or early research teams, providing disease-biology and in vivo model expertise to identify and advance projects within the global Bayer strategic frames; In preclinical programs, act as disease biology lead ensuring excellence in biology sounding as well as alignment and timely delivery of pharmacology related deliveries to efficiently advance programs towards milestones and go/no go decisions, including concise and regular presentation of program results to senior stakeholders; Support and contribute to the strategic development of the capability cluster "In Vivo", demonstrating scientific leadership and seeking innovative solutions (internally and externally) in the application of in vivo models to support our discovery pipeline; Support and contribute to the drug development strategy of CVRI, with particular focus on cardio-renal diseases, as well as the intersection of the cardiovascular, renal, and metabolic space; Collaborate with other R&D functions and support cross team and cross site activities; Contribute key documentation and presentations for projects moving through internal review stage gates and regulatory submissions; Employing VACC (Visionary, Architect, Coach, Catalyst) leadership principles to support management and coaching of research associates and junior scientists in a global matrix organization; Collaborate effectively with colleagues and interdisciplinary teams both within Bayer and with external collaborators; Assess external targets and programs to understand the competitive landscape and identify potential opportunities for collaboration, in-licensing or technological innovation; Maintain and extend a network with external partners from academia, contract research organizations and medical experts, with particular emphasis on the local Boston landscape; Foster creativity and motivation between scientists; Ensure that all tasks are aligned with respect to HSE guidelines, animal welfare law, documentation, and good research practices. D. in Biology (Cellular, Molecular or Developmental Biology), Biochemistry, or related life science field is required; Strong background in cardio-renal is essential, and further expertise in cardiovascular or metabolic space would be highly advantageous; Demonstrated track record in the drug discovery process in a pharmaceutical or biotech setting; A deep knowledge and hands-on experience in designing and establishing translatable in vivo rodent disease models to aid target identification and therapeutic evaluation; Deep expertise in the application of state-of-the-art in vivo models across the drug discovery process (including rodent mechanistic and disease models with clinically relevant read-outs and endpoints); Experience in the design and execution of early-stage research program(s) to identify and validate novel targets; Experience in strategic planning and project leadership.
NewDirector, Scientific Communications ReplimuneDirector, Scientific CommunicationsWoburn, MassachusettsThe RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response. Interfaces with senior levels across multiple cross-functional teams including pharmacovigilance, quality, medical directors/leads, field medical teams, commercial, regulatory, legal, and clinical development as well as external partners and serves as a medical information expert.
NewDirector, Research & Development Technology Scholar Rock Holding CorpDirector, Research & Development TechnologyCambridge, MA$200,000–$260,000 / yearScholar Rock is a late-stage global biopharmaceutical company focused on developing and commercializing apitegromab for children and adults with spinal muscular atrophy (SMA) and other rare, severe, and debilitating neuromuscular diseases. Summary of Position: Scholar Rock is seeking a Director of Research and Development Technology to cultivate strong functional partnerships to develop strategic solutions to Scholar Rock's growing research and development pipeline.
NewSenior Director, Chief Information Security Officer Scholar Rock Holding CorpSenior Director, Chief Information Security OfficerCambridge, MA$245,000–$325,000 / yearSummary of Position: Scholar Rock is seeking a Senior Director, Cybersecurity to serve as the company's Chief Information Security Officer, responsible for building and scaling enterprise cybersecurity capabilities that protect the organization's people, data, technology assets, intellectual property, and business operations. This role is ideal for a cybersecurity leader who has successfully led multiple cybersecurity functions and is ready to assume broader enterprise cybersecurity leadership responsibilities in a lean, high-growth biotechnology environment.
Director, Health Economics & Outcomes Research (HEOR) Azurity Pharmaceuticals - USDirector, Health Economics & Outcomes Research (HEOR)Woburn, MARemoteReporting to the VP, Market Access & Strategic Accounts, this individual owns the value-evidence strategy and deliverables — starting with D-PLEX100 and extending to future assets — and translates clinical and economic data into the tools that hospital, payer, and health-technology-assessment decision-makers require. As an industry leader in providing unique, accessible, and high-quality medications, Azurity leverages its integrated capabilities and vast partner network to continually expand its broad commercial product portfolio and robust late-stage pipeline.
Director, Controller eGenesisDirector, ControllerCambridge, MA$180,500–$233,500 / yearServe as the company’s primary technical accounting resource, researching and documenting positions on complex transactions including collaboration agreements, equity instruments, clinical trial accruals, in-process R&D, and lease accounting. Own the end-to-end financial close process, including general ledger, accounts payables, and accruals, delivering accurate and timely monthly, quarterly, and annual financial statements in compliance with U.S. GAAP.
Director Of Cmdb & Service Architecture TransMedics Group, Inc.Director Of Cmdb & Service ArchitectureAndover, MA$182,450–$227,550 / yearThe Director of Configuration Management Database (CMDB) & Service Architecture is responsible for establishing and governing the enterprise CMDB and service architecture framework to ensure accurate, dependency-aware visibility across all technology systems and business services. Proven experience integrating CMDB platforms with ITSM systems, discovery tools, cloud environments (Amazon Web Services), identity platforms, and automation workflows to provide accurate, near real-time visibility into enterprise assets and service dependencies.
Executive Director, Regulatory Affairs Beeline MedicinesExecutive Director, Regulatory AffairsBoston, Massachusetts$281,000–$344,000 / yearLed by an established executive team and backed by world-class life science investors, each day Beeline Medicines is determined to bring the scientific rigor and operational excellence to get to what matters for patients – realizing a world where people with immune-mediated diseases can live life fully. As a seasoned professional in Regulatory Affairs, develop Global Regulatory strategies and serve as the Global Regulatory Leader (GRL) for assigned Regulatory Project Teams to form global strategies and serve as the US Regulatory Lead (USRL) in the development of US regulatory approaches and execution of US filings.
Executive Director, Toxicology Centessa Pharmaceuticals, LLCExecutive Director, ToxicologyBoston, MA$270,000–$300,000 / yearServe as the primary nonclinical representative on Program Development Teams (PDTs) and at internal governance and external forums, effectively championing program strategy, presenting to regulatory authorities, and holding scientific ground with senior leadership, partners, CROs, and health authorities. Lead nonclinical sub‑teams as an integrated development head, providing cross‑functional oversight across Toxicology, DMPK, Bioanalytical Sciences, and Clinical Pharmacology to ensure aligned, program‑ready nonclinical strategies.
Senior Director, QC Laboratory Candel TherapeuticsSenior Director, QC LaboratoryNeedham, MA$258,000–$285,000 / yearCandel is a clinical stage biopharmaceutical company developing off the shelf, multimodal cancer immunotherapies designed to stimulate personalized, systemic anti tumor immune responses. This role partners closely with Quality Assurance, Analytical Development, R&D, Manufacturing, and other internal stakeholders to support clinical development activities and future organizational growth.
Director of Electrical & Systems Engineering TransMedicsDirector of Electrical & Systems EngineeringAndover, Massachusetts$203,050–$253,350 / yearProven experience designing, testing and formal verification of digital and analog designs, including electrostimulation or ECG monitoring, microprocessor-based electromechanical designs, analog front end data acquisition, motor control, communications interfaces, power supplies, and battery controller designs. Create documentation for electrical designs including formal cross-functional design reviews, theory of operation, DFMEA, and complete release packages consisting of fabrication drawings, assembly drawings, Gerber packages, and their design source files.
Sales Readiness, Associate Director - Remote UnitedHealth Group IncSales Readiness, Associate Director - RemoteBoston, MARemote$112,700–$193,200 / yearThis role is ideal for a forward-thinking leader who is passionate about modernizing and transforming workforce development, advancing sales effectiveness through technology, and delivering measurable business impact by equipping market-facing teams with modern, relevant, and future-ready learning experiences that are available when needed and deliver high impact across the Provider commercial organization. You will reimagine how market-facing teams build knowledge and skills by shifting from traditional classroom-based approaches to dynamic, AI-enabled, digital-first learning solutions that align with the expectations of today"s technology-savvy workforce to accelerate onboarding, strengthen adoption of key initiatives, and continuously build sales capabilities at scale.
Sr. Director/Vp, Biology Manifold BioSr. Director/Vp, BiologyBoston, MA$240,000–$340,000 / yearEducation and Experience: PhD in molecular biology, biochemistry, pharmacology, neuroscience, pathology, or a closely related discipline; 10+ years of biopharma R&D experience for VP level, or 7+ years for Senior Director level. Manifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening to unlock tissue-targeted medicines and organism-scale models of living systems.
Senior Director, Biotherapeutics Manifold BioSenior Director, BiotherapeuticsBoston, MA$240,000–$340,000 / yearThis role spans discovery and nonclinical development, including bioengineering strategies to generate best-in-class molecules and oversight of external contract manufacturing organizations (CDMOs) to develop processes and manufacture drug product for clinical trials. Manifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening to unlock tissue-targeted medicines and organism-scale models of living systems.
Regional Director, Sites Iterative Scopes Inc.Regional Director, SitesCambridge, MAThis role ensures operational excellence by aligning teams around key performance goals, elevating site capabilities, and maintaining consistency in trial execution. Knowledgeable about the critical elements for success in clinical trials: Ability to review protocols, programs, and assess the success of a project.
Director, Head Of Program Management Tessera TherapeuticsDirector, Head Of Program ManagementSomerville, MA$186,000–$239,000 / yearGuiding and empowering Program Managers to drive the development and management of integrated program plans (including timelines, assumptions, scenarios, risks, critical path, decision maps, goals, and budget drivers). Company Summary: Tessera Therapeutics is pioneering Gene Writing- a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source.
Senior Director, Corporate Quality - PV Sarepta Therapeutics Inc.Senior Director, Corporate Quality - PVBedford, MA$222,400–$278,000 / yearThis position will liaise with internal groups such as Pharmacovigilance Operations, Safety Evaluation & Risk Management, and Market Research, as well as external groups including contract auditors in an effort to ensure a high level of quality and consistency across the Sarepta platform; design and oversee the audit strategy; assist the GVP team in identifying and implementing corrective and preventive actions; and enable teams to be inspection ready, in support of a culture of sustainable compliance. Primary responsibilities include: Participate in the development of the internal and external Corporate Quality annual audit plan for GVP, REMS, PV vendors, interfaces, processes and preferred business partners and update the audit plan as needed based on identified risks and priorities.
Director, Epidemiology CSL PlasmaDirector, EpidemiologyWaltham, Pennsylvania$250,000–$280,000 / yearContribute epidemiological data in routine and ad hoc regulatory submissions documents (e.g., protocols, Product Clinical Development Plans, Risk Management Plans, Risk Evaluation and Mitigation Strategies, Periodic Safety Update Reports, Development Safety Update Reports, responses to Health Authority questions and requests). We use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives.
Senior Director, Head of Medical Evidence Generation CSL PlasmaSenior Director, Head of Medical Evidence GenerationWaltham, Delaware$303,000–$371,000 / yearThe Senior Director, Head of Medical Evidence reports into the Vice President, Head of Disease Areas and coordinates with Medical Affairs and cross-functional stakeholders to lead the Integrated Evidence Generation Plans (IEGP) for all marketed products and oversees the design and implementation of Medical Affairs evidence generation projects in alignment with GxP and business strategy. Provides subject matter expertise and consultation to Medical Affairs colleagues in study development and design and interact, as required, with external research partners including investigators and vendors (including but not limited to CROs, database owners, registries, et).
Director Of Network & Technology Resilience TransMedics Group, Inc.Director Of Network & Technology ResilienceAndover, MA$192,500–$240,100 / yearReporting directly to the Vice President of Information Security & Infrastructure Operations, this role bridges infrastructure engineering and cybersecurity by owning network configuration governance, cloud security architecture alignment, and enterprise disaster recovery engineering. This role will require close partnership with internal and external teams to ensure new and existing applications, systems, and services are aligned to network and cloud resiliency, recovery, and security frameworks.