NewPrincipal AI Scientist (Polytope Bio) Astera InstitutePrincipal AI Scientist (Polytope Bio)Emeryville, California$250,000–$350,000 / yearUnlike traditional non-profit research organizations, projects supported by Astera operate like high-velocity startups, allowing us to focus on ambitious goals, match structure to problem, and attract strong technical talent and leadership. The researcher in this role will work hands-on to develop and publish new reinforcement learning methods and bio AI models leveraging datasets created by our unique high-throughput biology platform.
NewSenior/Staff AI Scientist (Polytope Bio) Astera InstituteSenior/Staff AI Scientist (Polytope Bio)Emeryville, California$200,000–$300,000 / yearUnlike traditional non-profit research organizations, projects supported by Astera operate like high-velocity startups, allowing us to focus on ambitious goals, match structure to problem, and attract strong technical talent and leadership. The researcher in this role will work hands-on to develop and publish new reinforcement learning methods and generative AI models leveraging datasets created by our unique high-throughput biology platform.
Research Scientist, Life Sciences Computational Anthropic PBCResearch Scientist, Life Sciences ComputationalSan Francisco, CA$300,000–$320,000 / yearBuild, run, and maintain the analysis pipelines that back the team''s experimental programs: sequence analysis at petabyte scale, structural bioinformatics, phylogenetic and comparative genomics, design and analysis of high-throughput functional screens, biological sequence modeling, etc. You''ll bring broad computational biology experience to bear across the team''s projects, driving discoveries from large-scale computational analysis of biological data through to results our experimental scientists can test, and moving flexibly between problems as the science demands.
Scientist / Senior Scientist, Multiomics Applications Glyphic BiotechnologiesScientist / Senior Scientist, Multiomics ApplicationsBerkeley, CA$90,200–$147,600 / yearIn this role, you will independently execute and troubleshoot established sample preparation protocols across a broad range of biological inputs, generating high-quality data that supports ProSE performance benchmarking and Glyphic's broader multi-omic strategy, which combines ProSE, RNA-seq, DNA-seq, and Ribo-seq to identify neoantigens, biomarkers, and drug targets. Collaborate closely with proteomics, assay development, chemistry and data science teams to design experiments, interpret results, and guide project strategy — including cross-platform efforts (ProSE, RNA-seq, DNA-seq, ribosome profiling, and mass spectrometry).
Hybrid | Senior Biochemistry & Life Sciences Research Scientist — $55–$95/hour 24-MagHybrid | Senior Biochemistry & Life Sciences Research Scientist — $55–$95/hourSan Francisco, CaliforniaWe are sharing a specialised full-time opportunity for senior life sciences researchers with deep expertise in biochemistry, molecular and cell biology, genetics, immunology, neuroscience, structural biology, or related research disciplines. Clear progression into senior research responsibility, such as Senior Scientist, Staff Scientist, Research Scientist, Instructor, Principal Investigator , faculty member, or comparable level.
Principal Scientist, Lab Head, Metabolism Drug Discovery Genentech IncPrincipal Scientist, Lab Head, Metabolism Drug DiscoverySouth San Francisco, CA$143,200–$265,900 / yearInterdisciplinary Collaboration: Partner closely with internal teams across departments and disciplines, including Drug Development, Translational Medicine, Transcriptomics/Proteomics, Computational and Clinical Science, to drive innovative therapeutic strategies, formulate new therapeutic hypotheses and advance transformative medicines. Key Responsibilities and Attributes of the Principal Scientist: Lab focused and biology driven, building and managing a team (approximately 2-3 direct reports) of expert experimental biologists focused on cardiovascular and renal disease biology, target and drug discovery.
Scientist, Probe Design Bio-TechneScientist, Probe DesignNewark, California$89,300–$146,900 / yearThe Scientist will work within a highly dynamic group to develop and optimize new probe products based on our RNAscope® technology and work closely with our commercial team to identify and support customer needs. Our core RNAscope® technology is the world’s first multiplex fluorescent and chromogenic in situ hybridization platform capable of detecting and quantifying RNA biomarkers in situ at single molecule sensitivity.
Technical Support Scientist Bio-TechneTechnical Support ScientistNewark, CA$63,500–$104,450 / yearAdditionally, the role includes logging and tracking recurring support issues, collaborating with different departments for issue resolution, and contributing to the enhancement of the technical support team's knowledge database. Ensure excellence in customer service and guaranteed response times by actively monitoring support emails, phone calls, and ensuring all issues are resolved in a timely and comprehensive manner.
Open Application for Scientists and Research Associates Rezo TherapeuticsOpen Application for Scientists and Research AssociatesSan Francisco, CAOur Founders and members of the Board are a group of esteemed, world-class scientists from the University of California, San Francisco: Nevan Krogan, Kevan Shokat, Sourav Bandyopadhyay, Natalia Jura, as well as renowned biotech executives George Scangos and Norbert Bischofberger. Capitalizing on our Series A of $78M from top-tier investors, we are leveraging a unique integrated approach, combining capabilities in genetics, proteomics, structural biology and AI to generate deep biological insights and novel therapeutic approaches.
Senior Scientist, Cardiac Modeling InsitroSenior Scientist, Cardiac ModelingSouth San Francisco, CA$156,000–$166,000 / yearIn this role, you will own the development and application of iPSC-derived cardiomyocyte (iPSC-CM) models to study the genetic and molecular underpinnings of cardiovascular disease - working at the intersection of human stem cell biology, cardiac physiology, and scalable experimental platforms to generate the datasets that fuel our ML-driven drug discovery efforts. We work hard to bring together diverse teams-grounded in a wide range of expertise and life experiences-and work even harder to ensure those teams thrive in inclusive, growth-oriented environments supported by equitable company and team practices.
Scientist/Senior Scientist, CHO Cell Line Development Atum - DNA 2.0Scientist/Senior Scientist, CHO Cell Line DevelopmentNewark, CA$120,000–$150,000 / yearCRISPR & Host Cell Engineering: Design and execute target-specific CRISPR/Cas9 (and related gene-editing technologies) strategies for targeted gene knock-ins, knock-outs, and functional genomic modifications to optimize CHO host cell phenotypes. Bench-Heavy Laboratory Execution: Spend the majority of time (~80%) at the bench executing hands-on molecular biology, vector construction, CRISPR/gene editing, host cell engineering, transfection, and cell line generation experiments.
Scientist II, Genomic Core Xaira TherapeuticsScientist II, Genomic CoreSouth San Francisco, CA$124,000–$155,000 / yearYou will partner closely with Functional Genomics, Disease Biology, Automation, and Computational Biology teams to develop scalable sequencing strategies that support CRISPR-based perturbation studies, single-cell genomics, and other high-throughput discovery efforts. You will serve as a technical leader responsible for designing, developing, optimizing, and executing next-generation sequencing (NGS) workflows, with a primary focus on Illumina sequencing platforms, including MiSeq, NextSeq, and NovaSeq.
Scientist/Senior Scientist, Spatial Omics in Cells and Tissues Calico Life Sciences LLCScientist/Senior Scientist, Spatial Omics in Cells and TissuesSouth San Francisco, CA$160,000–$197,000 / yearCalico's highly innovative technology labs, its commitment to curiosity-driven discovery science, academic and industry partners, and vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs. Hands-on experience with proximity biotinylation techniques (i.e. BioID, APEX2, TurboID, BAR), including antibody conjugation strategies, fusion protein design, labeling kinetics optimization, and streptavidin-based enrichment.
Modeling Engineer/Scientist (Contract-to-Hire) Fulcrum Neuroscience, Inc.Modeling Engineer/Scientist (Contract-to-Hire)South San Francisco, CACollaborate with software developers in the AI-driven workflows and tooling that accelerate model development and analysis, including chat and visualization interfaces, to enable modelers and scientists to interact with BHN. This is an opportunity to work with pioneers in biological modeling and quantitative systems pharmacology (QSP) to make an impact on the treatment of neurodegenerative disease while working at the leading edge of modeling techniques and technology infused with AI.
Modeling Engineer/Scientist (Contract-to-Hire) (Remote) Fulcrum Neuroscience, Inc.Modeling Engineer/Scientist (Contract-to-Hire) (Remote)South San Francisco, CARemoteCollaborate with software developers in the AI-driven workflows and tooling that accelerate model development and analysis, including chat and visualization interfaces, to enable modelers and scientists to interact with BHN. This is an opportunity to work with pioneers in biological modeling and quantitative systems pharmacology (QSP) to make an impact on the treatment of neurodegenerative disease while working at the leading edge of modeling techniques and technology infused with AI.
Scientist I, Investigative Toxicology SGA Inc.Scientist I, Investigative ToxicologySouth San Francisco, CAThis individual must have experience in cell culture and will be responsible for: culturing and expanding primary cells and cell lines for in vitro screenings and performing assays which may include assessments of cytotoxicity and metabolic changes of cells, capturing cell culture images using high content imaging, flow cytometry, and other technologies. Will provide scientific and technical support to assays and platforms supported by the Investigative Toxicology group by: Performing experiments involving: immortalized and primary cell culture, cell viability assessment, Luminex/ELISAs, gene expression analysis, high content screening, confocal microscopy, and flow cytometry.
Scientist/Senior Scientist, Analytical Development & Characterization – Cell Therapy RetroScientist/Senior Scientist, Analytical Development & Characterization – Cell TherapyRedwood City, CAIn this role, you will design and execute characterization studies for intermediates and drug product, with a focus on flow cytometry, functional assays, product-related impurities and variants, MoA-reflective biological activity, and IND-enabling product understanding. We are seeking a new member of the Analytical Development team to drive hands-on, non-GMP analytical characterization studies for our iPSC-derived cell therapy products, including microglia and hematopoietic stem/progenitor cell programs.
Research Scientist Tabula BioResearch ScientistSan Francisco, CaliforniaThe core of our scientific work is the development of physics-based mathematical models of phage–bacteria interaction dynamics — how phages locate, bind to, infect, and replicate within bacterial targets at the population level — together with the large-scale numerical simulation of those models to identify and refine candidate therapies. We are looking for someone who is strong in numerical methods, large-scale simulation, and the modeling of complex dynamical systems, who likes difficult technical problems, and who wants to work on something where the connection between model quality and real-world impact is unusually direct.
Founding Machine Learning Scientist Tabula BioFounding Machine Learning ScientistSan Francisco, CaliforniaWe are looking for someone who is strong in modern machine learning, likes difficult technical problems, and wants to work on something where the connection between model quality and real-world impact is unusually direct. We are starting with bacteriophages, natural predators of bacteria, and building the models and experimental systems needed to design better therapies for hard-to-treat infections.
NewSenior Scientist RocheSenior ScientistPleasanton, CaliforniaWith a steady pipeline of high medical value predictive tests fueled by collaborations with over 85 pharmaceutical partners, we deliver diagnostic certainty through the broadest menu of immunohistochemistry/in situ hybridization (IHC/ISH) companion diagnostics available today. You have demonstrated Interpersonal skills: Strong verbal communication and influencing skills; can influence without authority and has proven experience building and cultivating relationships with key partners and stakeholders, both internally and externally.