Sr. Research Associate/Associate Scientist, Protein Biochemistry AllakosSr. Research Associate/Associate Scientist, Protein BiochemistryRedwood City, CaliforniaSenior Research Associate/Associate Scientist, Protein Biochemistry Allakos Inc. is a clinical-stage company developing therapeutic antibodies for inhibitory receptors on the surface of immune effector cells involved in allergic, inflammatory and proliferative diseases. Position Summary: We are seeking a highly motivated Senior Research Associate/Associate Scientist with a strong background in protein biochemistry to join our R&D team.
Senior Scientist, Membrane Protein Biochemistry (Onsite - 2 Year Fixed Term) Stanford UniversitySenior Scientist, Membrane Protein Biochemistry (Onsite - 2 Year Fixed Term)Stanford, CAStanford University''s Rogala Laboratory is seeking a Life Science Research Professional 3 (Senior Scientist, Membrane Protein Biochemistry) to perform complex functions and activities involved in defined research projects, and independently conduct a major portion of the research project(s) at the interface of protein biochemistry, structural biology, and quantitative assay development. Situated in a highly dynamic research environment within Stanford University School of Medicine and the Stanford Cancer Institute, the Rogala Laboratory investigates metabolic cell signaling on biological membranes, with particular focus on the mechanistic target of rapamycin (mTOR) pathway, solute carrier (SLC) transporters, and metabolic enzymes.
Scientist, Protein Biochemistry CareTechProsScientist, Protein BiochemistrySan Francisco, CaliforniaThe role involves characterizing and purifying proteins, supporting our drug discovery pipeline, and contributing to experimental design. The ideal candidate will have experience in protein biochemistry, purification techniques, and analytical methods to support our scientific and commercial goals.
Senior Scientist, Membrane Protein Biochemistry Amgen IncSenior Scientist, Membrane Protein BiochemistrySouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this vital role you will be part of an innovative integrative Protein Generation group within Discovery Protein Science, with responsibilities including (but not limited to) the design of strategies for recombinant production of polytopic membrane protein (MP) targets and their purification with detailed analytical characterization.
Scientist, Membrane Protein Biochemistry Amgen IncScientist, Membrane Protein BiochemistrySouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Part Time Biochemistry Research Assistant University of CaliforniaPart Time Biochemistry Research AssistantBerkeley, CA$23.97–$26.69 / hourAppointment Type: This is a Part Time 30 hour per week, non-exempt from overtime pay (hourly paid), 1 year, Term appointment with the possibility of extension or conversion to Career appointment based upon satisfactory job performance, continuing availability of funds and ongoing operational needs. Misconduct Disclosure Requirement: As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct, are currently being investigated for misconduct, left a position during an investigation for alleged misconduct, or have filed an appeal with a previous employer.
Tenure Track Assistant Professor of Biochemistry Santa Clara UniversityTenure Track Assistant Professor of BiochemistrySanta Clara, CA$105,122–$116,846 / yearProvide effective service to the Department of Chemistry & Biochemistry, the College of Arts and Sciences, the University, and the profession through contributions other than teaching and scholarship, such as service on committees, participation in professional organizations and activities, leadership, and community service performed by virtue of professional expertise or association with the university, as appropriate to rank and experience. The University offers many different opportunities to develop teaching skills through Faculty Development, including regular lunchtime workshops on pedagogy, teaching and technology grants, communities of practice, teaching mentors, and a scholarship of teaching and learning faculty group.
Quarterly Lecturer - Chemistry/Biochemistry Santa Clara UniversityQuarterly Lecturer - Chemistry/BiochemistrySanta Clara, CAPurpose: The Department of Chemistry at Santa Clara University, a Jesuit, Catholic university, invites applications for quarterly lecturer(s) (non-tenure track) to teach undergraduate courses including General Chemistry or Organic Chemistry labs. ADDITIONAL INFORMATION: Please note that your employment is subject to the terms of a collective bargaining agreement between the University and the Service Employees International Union Local 1021 ("Local 1021"; see https://www.scu.edu/provost/faculty-affairs/cba-ntt/ ).
Lecturer Pool for Department of Chemistry and Biochemistry AY 26-27 California State UniversityLecturer Pool for Department of Chemistry and Biochemistry AY 26-27Hayward, CA$5,507–$6,677In compliance with state and federal crime awareness and campus security legislation, including The Jeanne Clery Disclosure of Campus Security Policy and Crime Statistics Act, the Cal State East Bay Annual Campus Security Report is available here. DUTIES OF THE POSITION: The successful candidate will teach up to 15 contact hours per week in undergraduate laboratories and/or lectures, with assignments being consistent with the candidate's expertise and training, as well as the specific needs of the Department.
Protein Scientist LancesoftProtein ScientistFoster City, CA$40The successful candidate will work closely with scientists across Protein Science and Research to generate high-quality data and reagents, while contributing to efficient laboratory operations and experimental execution. This individual will contribute as a hands-on laboratory scientist, executing protein production, purification, and analytical workflows that support multiple CAR-T and cell therapy programs.
Associate Scientist, Protein Sciences CytomX Therapeutics IncAssociate Scientist, Protein SciencesSouth San Francisco, CA$115,000–$135,000 / yearAs part of this commitment, we (and the agencies we work with) will assist individuals who have a disability with any reasonable accommodation requests related to employment, including completing the application process, interviewing, completing any pre-employment testing, participating in the employee selection process, and/or to perform essential job functions where the requested accommodation does not impose an undue hardship. Our commitment to transforming lives with safer, more effective therapies is driven by our curiosity and passion for innovation and our belief that by acting with integrity in an honest, respectful, ethical manner, we have the power to change lives.
Associate Scientist, Protein Sciences CytomX TherapeuticsAssociate Scientist, Protein SciencesSouth San Francisco, CaliforniaAs part of this commitment, we (and the agencies we work with) will assist individuals who have a disability with any reasonable accommodation requests related to employment, including completing the application process, interviewing, completing any pre-employment testing, participating in the employee selection process, and/or to perform essential job functions where the requested accommodation does not impose an undue hardship. Our commitment to transforming lives with safer, more effective therapies is driven by our curiosity and passion for innovation and our belief that by acting with integrity in an honest, respectful, ethical manner, we have the power to change lives.
Staff Scientist, Protein Science (Computational) Pacific Biosciences of California IncStaff Scientist, Protein Science (Computational)Menlo Park, CA$148,200–$222,200 / yearThis high-visibility role provides an opportunity to lead early- to mid-stage protein engineering efforts from ideation through lead candidate optimization and to support late-stage development to ensure our products provide best-in-class long read NGS performance. PacBio (NASDAQ: PACB) is a premier life science technology company that designs, develops, and manufactures advanced sequencing solutions to help scientists and clinical researchers resolve genetically complex problems.
Scientist, Computational Protein Design AdimabScientist, Computational Protein DesignMountain View, CAFull timeYou will serve as the computational lead for protein design campaigns, embedded within a world-class team of modeling and wet-bench scientists, with direct access to Adimab's industry-leading experimental capabilities to drive the design-build-test cycle. Take end-to-end ownership of computational protein design campaigns — from design generation through wet-lab collaboration, analysis of experimental data, and optimization of the design-build-test cycle.
Associate Scientist - Protein GTT, LLCAssociate Scientist - ProteinSouth San Francisco, CAThe individual will contribute to multiple protein production requests, maintain accurate experimental records, and collaborate with cross-functional scientists to deliver high-quality protein reagents in a fast-paced research environment. Perform AKTA/FPLC-based purifications (Affinity, ion-exchange (IEX), hydrophobic interaction chromatography (HIC), size-exclusion chromatography (SEC), and other chromatography-based methods) with a focus on antibody-based molecules.
Computational Protein Design Latent Labs LtdComputational Protein DesignSan Francisco, CAUsing your blend of computational expertise and in-depth biochemical understanding of proteins, you will generate insights to improve protein functionality and operate at the interface between our machine learning and experimental platform units, working closely to seamlessly integrate AI generations and lab validation data. Before building Latent Labs, our team co-developed DeepMind's Nobel-prize winning AlphaFold, invented latent diffusion, and built pioneering lab data management systems as well as high throughput protein screening platforms.
Senior Scientist-Principal Scientist-Antibody Protein Engineering Prellis Biologics IncSenior Scientist-Principal Scientist-Antibody Protein EngineeringBerkeley, CACore activities:Reformat biologics across modalities (scFv, scFv-Fc, minibodies, Fab, VHH, Fc fusions, albumin fusions, TCRm) and assemble multispecifics (knob-in-hole, CrossMab, DVD-Ig, common LC, DARTs). We are committed to empowering our pharmaceutical partners with access to the most promising fully human antibody candidates rapidly identified from the human immune repertoire, enabling them to bring life-changing treatments to patients faster than ever before.
Scientist / Senior Scientist, Protein Engineering Kodiak Sciences IncScientist / Senior Scientist, Protein EngineeringPalo Alto, CAOur Antibody Biopolymer Conjugate Drug (ABCD) platform integrates protein and peptide engineering & discovery, polymer chemistry, small molecule drug discovery, bioconjugation, and drug delivery technologies to address high-prevalence ophthalmic diseases. D. in Medicinal Chemistry, Organic Chemistry, Chemical Biology, Biochemistry, or a related field, with either (i) 0-3 years of relevant postdoctoral experience and at least one first-author publication in a high-impact, peer-reviewed journal (preferred), or (ii) 3+ years of relevant industry experience.
Senior Field Application Scientist, Protein XI Meso Scale Diagnostics LLCSenior Field Application Scientist, Protein XISan Francisco, CAThis salary range represents a general guideline as MSD considers other factors when presenting an offer of employment, such as scope and responsibilities of the position, external market factors, and the candidate's knowledge, skills, abilities, education and experience. The Senior FAS, Protein XI will provide advanced technical support, engage in hands-on method development during an initial rotation at MSD headquarters, and mentor junior members of the Field Applications team.
Postdoctoral Fellow - Protein Sciences, Ciferri Lab Genentech IncPostdoctoral Fellow - Protein Sciences, Ciferri LabSouth San Francisco, CA$100,000–$106,500 / yearYou will have access to fully equipped with state-of-the-art facilities, including two Titan Krios & two Glacios microscopes equipped with Direct Detectors and Energy Filters, a virtually unlimited computer cluster for data processing, and have the opportunity to be fostered in one of the most productive and scientifically stimulating research environments. Expertise in protein purification, biophysical characterization, and structure determination of multi-protein complexes using X-ray crystallography and/or single-particle cryo-EM is required, as evidenced by a strong record of first-author publications in top peer-reviewed journals.
Postdoctoral Fellow-Discovery Protein Science Amgen IncPostdoctoral Fellow-Discovery Protein ScienceSouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Scientist II, ML - Guided Protein Design Evaluation Profluent IncScientist II, ML - Guided Protein Design EvaluationEmeryville, CA$147,000–$180,000 / yearYou will help scope targets and assays, partner with ML scientists to define what "model-ready" data looks like for each campaign, set and enforce assay readiness and QC expectations, and close the Design Build Test Learn loop by tracking how each dataset impacts model performance. You'll collaborate with ML and Protein Design scientists to develop experimental designs, review assay protocols, troubleshoot data quality issues with internal teams and CROs, and work closely with ML scientists to understand how data is used in model training.
Computational Chemist - Generative Molecule & Protein Design F. Hoffmann-La Roche LtdComputational Chemist - Generative Molecule & Protein DesignSanta Clara, CA$145,300–$269,800 / yearD. Computational Chemistry, Biochemistry, Biophysics, Structural Biology, or a highly quantitative related field or a Master's degree in Computational Chemistry, Biochemistry with 2 years of related experience or Bachelors with 3 years of related experience. You will join an innovative, collaborative environment where you will: Drive Molecular & Protein Design: Build and run structure-based and ligand-based virtual screening workflows to find new substrates, cofactors, and small molecules for our sequencing and biocatalysis platforms.
NewComputational Protein Designer Latent LabsComputational Protein DesignerSan Francisco, CAYour responsibilitiesLeverage our proprietary generative AI models to design proteins for experimental validation:Analyze protein design problems based on functional requirements, biochemistry, structural biology and sequence homologyGenerate designs using our proprietary generative AI models and optimize designs for experimental validationCoordinate with our lab-based protein engineers to plan and optimize the design process and validation strategyLeverage our proprietary data to improve our models:Analyze and leverage our experimental results to improve the next round of designs and increase our success rate over validation roundsCollaborate with machine learning scientists to fine-tune and prompt our modelsDevelop and execute biochemical assays for wet-lab validation:Develop and carry out experimental validation strategies for computationally designed proteins, including but not limited to: protein expression and purification, biophysical characterisation, and functional assays. Using your blend of computational expertise and in-depth biochemical understanding of proteins, you will generate insights to improve protein functionality and operate at the interface between our machine learning and experimental platform units, working closely to seamlessly integrate AI generations and lab validation data.
Protein Designer Arcadia Science LLCProtein DesignerEmeryville, CA$130,000–$180,000 / yearOur ideal candidate should have deep knowledge of proteins and how they function in a cellular context, as well as hands-on experience related to running design-build-test-learn loops. The scientist in this role will work to independently plan protein design projects, apply our tools and their ideas to generate proteins, and evaluate the biological function of the proteins they design both in vitro and in vivo.
Principal Scientist, Nonclinical Drug Safety Program Discovery Merck & Co IncPrincipal Scientist, Nonclinical Drug Safety Program DiscoverySouth San Francisco, CA$176,200–$277,300 / yearThey are responsible for 1) providing risk assessments for targets, 2) de-risking strategies for discovery programs and 3) collaborating with NDS staff at other sites to execute on the appropriate studies to support selection of therapeutic targets, and the identification and development of new drug candidates. The Discovery Program Leader is responsible for defining and overseeing the NDS strategy for programs in all modalities (including small molecules, peptides, biologics and ADC programs) from Target Identification through to the approval of First-In-Human enabling GLP toxicity studies.
Sr Manager, QA Operations Kyverna Therapeutics IncSr Manager, QA OperationsEmeryville, CA$160,000–$180,000 / yearProvide end-to-end oversight of Quality Operations across CDMOs (Plasmid, Viral Vector, and Cell Therapy Manufacturing and Testing), including Master Batch Record review and approval, product disposition, and continuous improvement of QA operational processes. This salary range is an estimate of what we reasonably expect to pay for this position, and the actual salary may vary based on various factors, including without limitation individual education, experience, tenure, skills and abilities, as well as internal equity and alignment with market data.
Senior Scientific Program Manager, ML - Guided Protein Design Evaluation Profluent IncSenior Scientific Program Manager, ML - Guided Protein Design EvaluationEmeryville, CA$131,000–$246,000 / yearYou will run campaigns end-to-end - tracking timelines across ML, Biology, Bioinformatics, and CROs - and you will own the CRO side of the program: sourcing vendors with suitable platforms, running technical and commercial evaluations, negotiating pricing and turnaround, and coordinating contracting with Legal and BD. MDE runs campaigns across internal labs and external CROs, and its operating tempo depends on tight program execution, well-run vendor relationships, and clean documentation.
Clinical Lab Technical Specialist Stanford Health CareClinical Lab Technical SpecialistPalo Alto, CA$80.95–$91.18 / hourServe as a technical resource to internal hospital laboratory staff, School of Medicine Medical Directors, external entities; develop policies and procedures; review technical work of others, solve complex technical problems; develop and validate new laboratory assays, develop teaching protocols/curriculums in addition to the essential technical functions of the lab. Conducts statistical analysis of tests using clinical laboratory techniques in chemistry, biochemistry, immunology, microbiology or related laboratory specialties.