Biochemistry Jobs in South San Francisco, CA
Nurix Therapeutics
San Francisco, CA
The candidate will creatively expand the capabilities of Nurix’s proteomics platform by integrating and developing customized tools for both global and targeted proteomics data analysis workflows. Expertise in:Bioinformatics analysis of proteomic datasets with a focus on global proteomics workflows; familiarity with targeted proteomics is also valuable.
Nurix Therapeutics
San Francisco, CA
The candidate will be expected to work independently and collaboratively across multiple Nurix groups (Discovery Biology, Medicinal Chemistry, DMPK), and to generate high quality, impactful results in an exciting and fast-paced research environment. The ideal candidate will have expertise in pharmacological profiling of small molecule drugs, xenograft and syngeneic tumor models, mammalian cell and molecular biology, and mechanisms of disease in oncology and inflammation.
JLSa2 Therapeutics, Inc
South San Francisco, CA
JLSa2 is a new and recently launched seed-stage venture backed company, located in South San Francisco, focused upon developing novel multifunctional protein-drug conjugate therapies to address human metabolic diseases and other non-oncology related diseases. Experience with cell-based potency and bioassay methods, cytotoxicity assays, reporter assays, proliferation assays, and/or ADCC, attention to detail and ability to organize multiple experiments with multiple analytes is required.
Amgen
South San Francisco, CA
The Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is seeking a highly motivated Computational Biologist with expertise in analyzing clinical biomarker data, including but not limited to genomics, transcriptomics, proteomics, spatial-omics, flow cytometry, immunoassays, and other biomarker assays. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
AbbVie
South San Francisco, CA
The GRC is widely recognized as a center of excellence in various fields, including bioinformatics, functional genomics, human genetics, pharmacogenomics, and the study of multiple population cohorts, with a database containing over 1 million genomes. It plays a vital role in our pursuit of world-class genetics and genomics research by focusing on identifying the most suitable targets and enhancing our understanding of not only human disease biology but also the behavior and response of our drugs in clinical trials.
IDEAYA Biosciences
South San Francisco, CA
Along with our inspiring mission, and highly collaborative and inclusive environment, IDEAYA offers a competitive total rewards package that reflects our pay-for-performance philosophy where employees are eligible to be considered for merit-based salary increases, company discretionary short-term incentive plan participation, and company discretionary stock option awards (based on board approval). The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the office location where this open position is located, the final candidates’ experience within their profession, experience in the disease areas we are striving to make an impact in as a company, length of time within the industry, educational background, and performance during the interview process.
SonoThera
South San Francisco, CA
SonoThera is a venture capital-backed early-stage biopharmaceutical company developing ultra-sound-guided non-viral targeted gene therapies to treat multiple diseases of high unmet need. This salary range is an estimate, and the actual salary may vary based on various factors, including, without limitation, individual education, experience, tenure, skills, and abilities, as well as internal equity and alignment with market data, including potential adjustments for geographic location.
Maze Therapeutics
South San Francisco, CA
About Maze TherapeuticsMaze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. The company is advancing a pipeline using its Compass platform, which allows it to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process it refers to as variant functionalization.
Dren Bio
Foster City, CA
In addition to DR-01, the Company has launched multiple programs from its proprietary Targeted Myeloid Engager and Phagocytosis Platform, a bispecific antibody-based technology that offers a novel mechanism of action focused on selectively engaging myeloid cells (antigen presenting cells) for the targeted depletion of pathologic cells and other disease-causing agents. The candidate will work with a cross-functional team of scientists (immunologists, cell biologists, biochemists, and protein engineers) to advance research stage programs into early clinical development.
AbbVie
South San Francisco, CA
The QTAS department supports Discovery and Development Projects by generating in vitro ADME data, pharmacokinetics characterization, prediction of human efficacious dose/pk, drug-drug interactions (DDI) and in vitro to in vivo extrapolations towards the development of clinical candidates. A masters or bachelors degree in relevant field (pharmacy, pharmacology, pharmaceutical sciences, biological chemistry or equivalent in drug metabolism or related discipline) with relevant industry experience in drug discovery/ development (+2 years with MS; +5 years with B.S).
JLSa2 Therapeutics, Inc
South San Francisco, CA
JLSa2 Therapeutics is a new and recently launched seed-stage venture backed company, located in South San Francisco, focused upon developing novel multifunctional protein-drug conjugate therapies to address human metabolic diseases and other non-oncology related diseases. The candidate will work in a highly collaborative team with the conjugation and biophysical analytical teams, as well as senior leadership, to ensure data integration across functional areas to ensure rapid decision making and product iteration cycle time.
Amgen
South San Francisco, CA
The Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is looking for a highly motivated Computational Biologist with expertise in clinical bioinformatics, biomarker development, assay development, ML algorithms & data science, statistical modeling, handling clinical data sets, and a background in biology and computational sciences. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Maze Therapeutics
South San Francisco, CA
About Maze TherapeuticsMaze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. The company is advancing a pipeline using its Compass platform, which allows it to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process it refers to as variant functionalization.
Dren Bio
Foster City, CA
In addition to DR-01, the Company has launched multiple programs from its proprietary Targeted Myeloid Engager and Phagocytosis Platform, a bispecific antibody-based technology that offers a novel mechanism of action focused on selectively engaging myeloid cells (antigen presenting cells) for the targeted depletion of pathologic cells and other disease-causing agents. Your primary role will be to design and analyze multi-omic experiments using pre-clinical models and patient samples, with the aim of generating critical insights into the biology and progression of autoimmunity and cancer.
Nurix Therapeutics
San Francisco, CA
Experience working with bioanalytical tools such as hydrophobic interaction chromatography (HIC), preparative-scale size exclusion chromatography (SEC), liquid chromatography-mass spectrometry (LC-MS), ion-exchange (IEX), and reversed phase (RP)-HPLC, Nuclear Magnetic Resonance (NMR) Spectroscopy. The successful candidate will have the opportunity to directly contribute to the following key platform operations: Develop, optimize and implement high-throughput bioconjugation processes through the application of established and state-of-the-art technologies.
Amgen
South San Francisco, CA
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Amgen
South San Francisco, CA
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Maze Therapeutics
South San Francisco, CA
About Maze TherapeuticsMaze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. We are advancing a pipeline using our Compass platform, which allows us to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process we refer to as variant functionalization.