NewPrincipal Scientist – Surface Biology Early Validation Lead AmgenPrincipal Scientist – Surface Biology Early Validation LeadThousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related) Amgen IncAssociate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related)Thousand Oaks, CA$182,465–$246,865 / yearThe Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is seeking a highly motivated Computational Biologist with expertise in analyzing clinical biomarker data, including but not limited to metabolomics, genomics, transcriptomics, proteomics, spatial-omics, flow cytometry, immunoassays, and other biomarker assays. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Senior Biology Teacher MyEdSpaceSenior Biology TeacherLos Angeles, CaliforniaRemoteBacked by $15m in Series A funding from some of the leading investors in the space, we're ready to scale - and we want you to help us build and scale MyEdSpace as part of a collaborative and ambitious team. If you’re motivated by solving meaningful problems and creating real impact through your work on a societal level and make a real impact on the world - we’d love to hear from you!
Biology Instructor, Part-Time Rio Hondo Community CollegeBiology Instructor, Part-TimeWhittier, CAMinimum Qualifications Masters degree in any biological science OR Bachelors degree in any biological science AND Masters in biochemistry biophysics or marine science OR The equivalent OR A valid California Community College Credential authorizing service in the appropriate subject matter ANDDemonstrate a sensitivity to and understanding of the diverse academic socioeconomic cultural disability gender identity sexual orientation and ethnic backgrounds of community college students. Río Hondo College offers 30 associate degrees that guarantee transfer ADTs to Cal State Universities a bachelors degree in Automotive Technology more than 60 certificates a Pathway to Law School dual enrollment with K-12 districts state championship speech & debate team top-notch athletic teams student leadership opportunities travel abroad experiences and more.
Chemistry/Biology Teacher 26/27 SY Culver City Unified School DistrictChemistry/Biology Teacher 26/27 SYCulver City, CA$60,904–$120,579 / yearCULVER CITY UNIFIED SCHOOL DISTRICT At Culver City Unified School District, we take our responsibility seriously and are committed to excellence for all students in what we call The 4 A s: Academics, Athletics, Activities, and The Arts. Taking a Whole Child approach, our vision is that 100% of our students graduate from high school with unlimited opportunities in college and career, and are prepared to be successful in everything they endeavor to try.
Research Associate - Biology II RD PartnersResearch Associate - Biology IISanta Monica, California£82,135–£102,683Perform routine laboratory procedures including ddPCR, qPCR, Flow, Luminex/MSD for ELISA and various cell-based immunoassays and biochemical assays. R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering.
Postdoctoral Scholar - Department of Ecology and Evolutionary Biology University of California Los AngelesPostdoctoral Scholar - Department of Ecology and Evolutionary BiologyLos Angeles, CAPostdoctoral Scholar - Department of Ecology and Evolutionary Biology - University of California Los Angeles.
LECTURER (MAMMALIAN PHYSIOLOGY AND MECHANISMS OF DISEASE) FOR 2026-2027, INTEGRATIVE BIOLOGY AND PHYSIOLOGY University of California Los AngelesLECTURER (MAMMALIAN PHYSIOLOGY AND MECHANISMS OF DISEASE) FOR 2026-2027, INTEGRATIVE BIOLOGY AND PHYSIOLOGYLos Angeles, CALECTURER (MAMMALIAN PHYSIOLOGY AND MECHANISMS OF DISEASE) FOR 2026-2027, INTEGRATIVE BIOLOGY AND PHYSIOLOGY - University of California Los Angeles.
LECTURER (PROFESSIONAL AND CAREER DEVELOPMENT FOR PRE-HEALTH STUDENTS) FOR 2026-2027, INTEGRATIVE BIOLOGY AND PHYSIOLOGY University of California Los AngelesLECTURER (PROFESSIONAL AND CAREER DEVELOPMENT FOR PRE-HEALTH STUDENTS) FOR 2026-2027, INTEGRATIVE BIOLOGY AND PHYSIOLOGYLos Angeles, CALECTURER (PROFESSIONAL AND CAREER DEVELOPMENT FOR PRE-HEALTH STUDENTS) FOR 2026-2027, INTEGRATIVE BIOLOGY AND PHYSIOLOGY - University of California Los Angeles.
Staff Research Associate 1 Stem Cell & Mitochondrial Biology UCLA Health SystemStaff Research Associate 1 Stem Cell & Mitochondrial BiologyLos Angeles, CA$28.69–$34.21 / hourb'nn n n n n n n n n n n n nn n n n n n n n n n n n n n n n n n Staff Research Associate 1, Stem Cell & Mitochondrial Biology - - 29206 - UCLA Healthn n nnnn nn n n n nn n n n n Skip to content nn n n n n n UCLA Health Home Page n n nn nnn n nn n Main menu. Press enter or space keys to expands and escape key to collapse nn n ...
NewDirector of Biology & Biochemistry Eli Lilly and CoDirector of Biology & BiochemistryPasadena, CA$163,500–$281,600 / yearOur current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL). Characterize complete functionality of protein reagents, provide both insight and oversight into quality and tracking of protein reagents, be able to independently lead a small team of biochemists and biologists to support a large molecule discovery group with various targets and assets at different stages of discovery.
26-27 Biology Teacher - Valor Academy High School Bright Star Schools26-27 Biology Teacher - Valor Academy High SchoolLos Angeles, CA$63,600–$137,400 / yearOther Benefits: Job-embedded induction program for new teachers with a preliminary teaching credential to earn their CA clear credential at no cost to the participant Weekly instructional coaching or mentoring (through our in-house induction program referenced above) for all teachers Instructional leaders as principals Pupil-free planning days for teachers Staff wellness program School counselors to support with family engagement and communication Opportunity to participate in stipended out of area and out of state life experience lessons (field trips). What you'll bring Bachelor's degree Single Subject CA credential in the applicable subject area Candidates with an intern credential are also considered Possession of either an English Learner Authorization (EL Authorization), Bilingual, Cross-Cultural, Language and Academic Development (BCLAD) certificate; Cross-Cultural, Language and Academic Development (CLAD) certificate; or Bilingual Certificate of Competence (BCC) required.
26-27 Biology Teacher - Rise Kohyang High School Bright Star Schools26-27 Biology Teacher - Rise Kohyang High SchoolLos Angeles, CA$63,600–$137,400 / yearOther Benefits: Job-embedded induction program for new teachers with a preliminary teaching credential to earn their CA clear credential at no cost to the participant Weekly instructional coaching or mentoring (through our in-house induction program referenced above) for all teachers Instructional leaders as principals Pupil-free planning days for teachers Staff wellness program School counselors to support with family engagement and communication Opportunity to participate in stipended out of area and out of state life experience lessons (field trips). What you'll bring Bachelor's degree Single Subject CA credential in the applicable subject area Candidates with an intern credential are also considered Possession of either an English Learner Authorization (EL Authorization), Bilingual, Cross-Cultural, Language and Academic Development (BCLAD) certificate; Cross-Cultural, Language and Academic Development (CLAD) certificate; or Bilingual Certificate of Competence (BCC) required.
Biology - Graduates - AI Training - USA Prolific Academic LtdBiology - Graduates - AI Training - USALos Angeles, CAWe're looking for Biology Experts and Life Science Professionals to join our Expert Network to help train and evaluate cutting-edge AI models using real scientific expertise. We've built a unique platform that connects researchers and companies with a global pool of participants, enabling the collection of high-quality, ethically sourced human behavioural data and feedback.
Senior Developer Relations Manager - Digital Biology Partnerships NVIDIA CorpSenior Developer Relations Manager - Digital Biology PartnershipsCAProven experience structuring and implementing complex technical engagements, negotiating requirements, prioritizing issues, and collaborating with internal or external partners (across sales, legal, product or marketing teams as needed). At least 5 years of direct, hands-on experience managing scientific alliances and collaborative programs in drug discovery-covering computer-aided drug discovery, informatics, agentic agents, and other digital research workflows.
New26-27 Physics & Biology Teacher - Valor Academy High School Bright Star Schools26-27 Physics & Biology Teacher - Valor Academy High SchoolLos Angeles, CA$63,600–$137,400 / yearOther Benefits: Job-embedded induction program for new teachers with a preliminary teaching credential to earn their CA clear credential at no cost to the participant Weekly instructional coaching or mentoring (through our in-house induction program referenced above) for all teachers Instructional leaders as principals Pupil-free planning days for teachers Staff wellness program School counselors to support with family engagement and communication Opportunity to participate in stipended out of area and out of state life experience lessons (field trips). What you'll bring Bachelor's degree Single Subject CA credential in the applicable subject area Candidates with an intern credential are also considered Possession of either an English Learner Authorization (EL Authorization), Bilingual, Cross-Cultural, Language and Academic Development (BCLAD) certificate; Cross-Cultural, Language and Academic Development (CLAD) certificate; or Bilingual Certificate of Competence (BCC) required.
Biology Teacher - Resume Drop ICEF Public SchoolsBiology Teacher - Resume DropLos Angeles, CaliforniaTo achieve this goal, we equip teachers with essential resources, including curriculum maps, a comprehensive repository of instructional materials and videos, interim assessments and item banks, individualized coaching, weekly professional development, and the support to implement innovative strategies. Our Mission: ICEF's mission is to educate and empower courageous leaders to embrace their full potential for college, career, and life by providing a community that honors each student's unique identity, fosters academic excellence, nurtures healthy minds, and inspires critical thinkers.
Staff Research Associate 1, Stem Cell & Mitochondrial Biology University of CaliforniaStaff Research Associate 1, Stem Cell & Mitochondrial BiologyLos Angeles, CA$28.69–$34.21 / hourAs a condition of employment, the final candidate who accepts an offer of employment will be required to disclose if they have been subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct; or have filed an appeal of a finding of substantiated misconduct with a previous employer. Duties include: Perform tissue culture to maintain mammalian primary cells, established cell lines, and induced pluripotent stem cell (iPSC) lines.
2026-27 Science Teacher (Biology, Chemistry and/or Physics) Magnolia Educational and Research Foundation2026-27 Science Teacher (Biology, Chemistry and/or Physics)Van Nuys, CA$61,000–$85,000 / yearNOTICE: Applicants for certificated positions are required to provide a complete list of prior school employers (school districts, county office of education, charter school and/or state special school) regardless of the length of service. ONE OF OUR LONG-TERM COMPETITIVE ADVANTAGES IS THE CALIBER OF OUR PEOPLE: Magnolia Public Schools bring together smart, talented people from a diversity of backgrounds, where they can bring their "whole self" to work as well as their PASSION for teaching and learning.
Biology Teacher, High School (2026-27 School Year) SYNERGY ACADEMIESBiology Teacher, High School (2026-27 School Year)Los Angeles, CAConduct periodic assessments of student academic progress in order to guide instruction and to ensure that the academic goals of the students and the school are met. Scaffold and differentiate lessons for students and provide intervention and enrichment as necessary to address students' specific needs.
NewMarine Biology and Anatomy Teacher Partnerships to Uplift Communities SchoolsMarine Biology and Anatomy TeacherLos Angeles, CAPartnerships to Uplift Communities (PUC) Schools is comprised of a non-profit network of public charter schools designed to significantly increase high school graduation rates, college entrance, and college graduation rates for underserved students in North-East Los Angeles, and the North-East San Fernando Valley. An incumbent may be asked to perform other duties as required Management reserves the right to add, modify, change, or rescind the work assignments of different positions and to make reasonable accommodations so that qualified employees can perform the essential functions of the job.
2026-27 Biology Teacher Alliance College-Ready Public Schools2026-27 Biology TeacherLos Angeles, CaliforniaProfessional Development: At Alliance, we believe in supporting teacher growth and providing substantial school-based and network-wide professional development support for teachers, including two weeks of professional development for new hires that introduce the Alliance culture and build classroom management and instructional planning skills. Alliance College-Ready Public Schools is one of the largest and most successful nonprofit public charter school networks in the nation, operating 25 high-performing, middle and high schools that educate nearly 13,000 scholars who make up the heart of Los Angeles’ Latinx, Black, and recent immigrant communities.
Bioprocess Development Engineer PBS BiotechBioprocess Development EngineerCamarillo, CAFull timeOur proprietary single-use bioreactor technology is transforming the scalability and efficiency of cell and gene therapy production—helping bring breakthrough treatments to patients faster. In this role, you will work hands-on with advanced bioreactor systems and diverse cell types, supporting the development of scalable manufacturing processes for emerging therapies.
Senior Scientist - siRNA Off-Target Analysis Amgen IncSenior Scientist - siRNA Off-Target AnalysisThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this vital role you will apply expertise in transcriptomics, computational biology, data visualization, and mechanistic interpretation to design and execute off-target assessments for siRNA experiments, and deliver weight-of-evidence reports and regulatory draft reports.
Project Scientist-Biological Chemistry UCLA Fielding School of Public HealthProject Scientist-Biological ChemistryLos Angeles, CA$76,700–$201,900 / yearJob responsibilities include supporting the PI in the design and execution of funded projects, including preparation of samples for MicroED (macromolecular and small molecules, materials etc), optimization of parameters for MicroED including all aspects of sample preparation, data collection, data archiving and management, microscope optimization, data analysis, structure solution, pipeline optimization, paper writing and submission, grant writing, mentoring and teaching other lab members, writing budget and progress reports as required, day-to-day tasks related to project management, supervising graduate/undergraduate students, other postdoctoral fellows and technicians in the group as needed and engaging in collaborations as directed by the PI. The University of California promotes the social mobility of its students, equips them with the tools and experience that furthers their ambitions, and regards their accomplishments across the life span as evidence of the profoundly positive impact of higher education.
Scientist - Urban Wildlands Center for Biological DiversityScientist - Urban WildlandsCARemote$55,000–$75,000 / yearPhysical Reading (ingest data): [ ] Rarely [ ] Occasionally [X] Frequently Working on a computer: [ ] Rarely [ ] Occasionally [X] Frequently Typing: [ ] Rarely [ ] Occasionally [X] Frequently Writing by hand: [ ] Rarely [X] Occasionally [ ] Frequently Sitting: [ ] Rarely [ ] Occasionally [X] Frequently Walking: [ ] Rarely [X] Occasionally [ ] Frequently Standing: [ ] Rarely [X] Occasionally [ ] Frequently Lift/Carry 0-25 lbs: [ ] Rarely [X] Occasionally [ ] Frequently Lift/Carry 25-75 lbs: [X] Rarely [ ] Occasionally [ ] Frequently Hiking: [ ] Rarely [X] Occasionally [ ] Frequently Climbing up or down stairs: [ ] Rarely [X] Occasionally [ ] Frequently Bending: [X] Rarely [ ] Occasionally [ ] Frequently Squatting: [X] Rarely [ ] Occasionally [ ] Frequently Reaching overhead: [X] Rarely [ ] Occasionally [ ] Frequently Repetitive motions: [ ] Rarely [ ] Occasionally [X] Frequently Ability to drive: [X] Rarely [ ] Occasionally [ ] Frequently. The Urban Wildlands program aims to stop development and land use policies that threatens critical wildlife habitat, creates pollution, disrupts hydrology and freshwater systems, exhausts limited water supplies, increases wildfire risk, amplifies climate change, and drives species extinction.
Associate Scientist - In Vivo Pharmacology Amgen IncAssociate Scientist - In Vivo PharmacologyThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Technical Director - Biological Resources GHD Group Pty LtdTechnical Director - Biological ResourcesLos Angeles, CA$147,000–$245,000 / yearCommunity of Practice Management: Contribute strongly on a strategically significant area to a community of practice in a defined area of expertise or consulting, or lead on an area of expertise or consulting practice, to contribute to thought leadership and to develop innovative practice among colleagues. The ideal candidate must be recognized as an industry leader and have significant experience in wildlife biology, botany and/or wetland science; business development; contributing to growth of practice areas; overseeing the environmental review process; and winning and leading projects of importance.
Research Scientist California Institute of TechnologyResearch ScientistPasadena, CAWork directly with Senior Scientist Dr. Brian Williams and with CI2 (Cell Interaction Initiative) and SPEC (Single-Cell Profiling Center) PIs, post docs, and grad students to execute projects that use state of the art transcriptomics and multiomics platforms (single-cell; single nucleus; spatial); test and assure quality control of assays; troubleshoot assays as needed. Have interest, experience, and desire to work as part of a small team developing new methods; conducting benchmarking; and obtaining reference-grade data for internal Caltech and public release and publication as part of solving major biology and biomedical problems in the domain of cell identity and cell interactions.
Clinical Lab Scientist - Per Diem Days Valley Presbyterian HospitalClinical Lab Scientist - Per Diem DaysVan Nuys, CAAt Valley Presbyterian Hospital, our Clinical Laboratory team plays a vital role in delivering timely, accurate diagnostic testing that supports high-quality care for patients across the lifespan. We are seeking a dedicated Clinical Laboratory Scientist to perform laboratory testing and analysis of biological specimens while supporting quality control, instrument maintenance, and overall laboratory operations.
Associate, Manufacturing ImmunityBio IncAssociate, ManufacturingCulver City, CAImmunityBio, Inc. (NASDAQ: IBRX) is a commercial-stage biotechnology company developing cell and immunotherapy products that are designed to help strengthen each patient's natural immune system, potentially enabling it to outsmart the disease and eliminate cancerous or infected cells. • ImmunityBio is developing cutting-edge technology with the goal to transform the lives of patients with cancer and develop next-generation therapies and vaccines that complement, harness and amplify the immune system to defeat cancers and infectious diseases.
Senior Scientist Amgen IncSenior ScientistThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Serve as a Safety Pharmacology subject matter expert on cross-functional project teams, developing fit-for-purpose strategies and providing strategic guidance across discovery, lead optimization, candidate selection, IND-enabling, and clinical development stages, aligned with program biology, modality, target risk, regulatory expectations, and development needs.
Senior Scientist - Translational Safety & Risk Sciences (TSRS) Amgen IncSenior Scientist - Translational Safety & Risk Sciences (TSRS)Thousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
NewProcess Development Senior Scientist Amgen IncProcess Development Senior ScientistThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this vital role you will be responsible for analytical and biochemical characterization activities for pre-clinical biotherapeutic protein development including assay development for biochemical characterization with emphasis on mass spectrometry and liquid chromatography, planning and execution in support of pre-clinical candidate selection, process development and lead molecule characterization.
Associate Scientist 1 Xencor IncAssociate Scientist 1Pasadena, CA$95,500–$121,250 / yearStrong hands-on experience with mammalian cell culture, transient/stable cell line generation, and cell-based antibody screening assays, including binding and competition assays, reporter assays, and related screening technologies. The ideal candidate will bring strong experimental and troubleshooting skills, with an interest in or experience leveraging automation, data analysis tools, and AI-assisted technologies to enhance assay workflows, data processing, and reporting capabilities.
Machine Learning Scientist Amgen IncMachine Learning ScientistThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Sr Machine Learning Scientist AmgenSr Machine Learning ScientistThousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Safety Pharmacology Senior Scientist AmgenSafety Pharmacology Senior ScientistThousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Serve as a Safety Pharmacology subject matter expert on cross-functional project teams, developing fit-for-purpose strategies and providing strategic guidance across discovery, lead optimization, candidate selection, IND-enabling, and clinical development stages, aligned with program biology, modality, target risk, regulatory expectations, and development needs.