Associate Director, Global Biomarker Lead, Inflammation, GI2 TAU Takeda Pharmaceutical Co LtdAssociate Director, Global Biomarker Lead, Inflammation, GI2 TAUBoston, MA$154,400–$242,550 / yearLead the Translational Sub-Team (TST) and provide matrix leadership across multiple functional areas, working closely with physician scientists, clinical leads, clinical pharmacologists, TBB, nonclinical scientists, and discovery research scientists to build consensus around a fit-for-purpose biomarker strategy. The role is responsible for independently developing translational biomarker plans as part of the overall asset strategy across Discovery and Global Product Teams, supporting programs through clinical development and post-market activities, and ensuring timely delivery of high-quality biomarker data.
Frontend Lead TechDigitalFrontend LeadFramingham, MAThe ideal candidate will have strong proficiency in modern JavaScript, ReactJS (v18+), and frontend testing frameworks, as well as experience with server-side rendering (SSR). Yes/No ReactJS (v18+) JavaScript (ES6+) JEST React Testing Library (RTL) SCSS/SASS .
Software Engineering Lead Data Engineer MFS InvestmentsSoftware Engineering Lead Data EngineerBoston, MA$110,000–$158,500 / yearWellness Programs: Robust wellness webinars, employee assistance program with a focus on mental health, subsidized fitness benefit via Wellhub (formerly Gympass), where you can workout at gyms, studios and boutique fitness locations near you, join virtual personal training sessions and access a wide variety of well-being apps. This initiative enables enhanced investment decision making, risk management and client reporting for our multi-asset platform by delivering consistent, timely, accurate and user-friendly data to investors, risk teams and clients.
NewSoftware Production Support Lead HealthfirstSoftware Production Support LeadBoston, MA$94,100–$136,000 / yearIf you have a disability under the Americans with Disability Act or a similar law and want a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to careers@Healthfirst.org or calling 212-519-1798. Log detailed and comprehensive bug reports for the development team, including steps to reproduce the error, screenshots, SQL query results if necessary, and any other relevant diagnostic information.
Collateral Technology Platform Lead – Managing Director State StreetCollateral Technology Platform Lead – Managing DirectorQuincy, Massachusetts$170,000–$282,500 / yearSuccess in this role requires a leader who can balance operational excellence with strategic transformation, build high-performing teams, strengthen accountability and ownership, and serve as a trusted partner to senior business leaders, operations executives, regulators, and clients. This leader will be accountable for end-to-end technology outcomes, including engineering execution, platform stability, operational resilience, client commitments, risk management, and strategic modernization.
Collateral Technology Platform Lead - Managing Director State Street CorpCollateral Technology Platform Lead - Managing DirectorQuincy, MA$170,000–$282,500 / yearSuccess in this role requires a leader who can balance operational excellence with strategic transformation, build high-performing teams, strengthen accountability and ownership, and serve as a trusted partner to senior business leaders, operations executives, regulators, and clients. This leader will be accountable for end-to-end technology outcomes, including engineering execution, platform stability, operational resilience, client commitments, risk management, and strategic modernization.
Principal Scientist, Oligonucleotide PMO, ASO Development Dyne Therapeutics IncPrincipal Scientist, Oligonucleotide PMO, ASO DevelopmentWaltham, MA$159,000–$200,000 / yearThis role will ensure the delivery of robust, scalable, and cost-effective manufacturing processes, serve as the primary technical lead for external CDMOs, driving aggressive timelines while delivering well-characterized products optimized for our proprietary bioconjugation platform. Define Analytical Strategy: Support analytical development, focusing on robust impurity control strategies, raw material specifications, and comprehensive physicochemical characterization for both oligonucleotide payloads and conjugated protein drug substances.
Associate Director, Oligonucleotide Development Dyne Therapeutics IncAssociate Director, Oligonucleotide DevelopmentWaltham, MA$159,000–$195,000 / yearThe role will ensure the delivery of robust, scalable, and cost-effective manufacturing processes, serve as the primary technical lead for external CDMOs, driving aggressive timelines while delivering well-characterized products optimized for our proprietary bioconjugation platform. Define Analytical Strategy: Set the vision for analytical development, focusing on robust impurity control strategies, raw material specifications, and comprehensive physicochemical characterization for both payloads and conjugated drug substances.
Lead Construction Plumber Work With Your HandzLead Construction PlumberLincoln, RI$35–$45 / hourYou will be a key leader on the job site, ensuring high-quality work, providing guidance to team members, and communicating with the foreman to resolve any issues. As a Lead – Construction Plumber, you will be responsible for leading plumbing system installations for commercial and residential construction projects.
Senior Lead AI Engineer (AI Foundations: LLM Customization, Finetuning, Reinforcement Learning) Capital One Financial CorpSenior Lead AI Engineer (AI Foundations: LLM Customization, Finetuning, Reinforcement Learning)Cambridge, MA$229,900–$262,400 / yearBasic Qualifications: Bachelor's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 6 years of experience developing AI and ML algorithms or technologies, or a Master's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 4 years of experience developing AI and ML algorithms or technologies. In this role, you will: Partner with a cross-functional team of engineers, research scientists, technical program managers, and product managers to deliver AI-powered products that change how our associates work and how our customers interact with Capital One.
Lead AI Engineer (AI Foundations, VLM Customization) Capital One Financial CorpLead AI Engineer (AI Foundations, VLM Customization)Cambridge, MA$197,300–$225,100 / yearBasic Qualifications: Bachelor's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 4 years of experience developing AI and ML algorithms or technologies, or a Master's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 2 years of experience developing AI and ML algorithms or technologies. In this role, you will: Partner with a cross-functional team of engineers, research scientists, technical program managers, and product managers to deliver AI-powered products that change how our associates work and how our customers interact with Capital One.
Lead Software Engineer, Full Stack Capital OneLead Software Engineer, Full StackBoston, MassachusettsUtilize programming languages like JavaScript, Java, HTML/CSS, TypeScript, SQL, Python, and Go, Open Source RDBMS and NoSQL databases, Container Orchestration services including Docker and Kubernetes, and a variety of AWS tools and services. Share your passion for staying on top of tech trends, experimenting with and learning new technologies, participating in internal & external technology communities, mentoring other members of the engineering community.
Lead Data Engineer - Risk Tech (Python, AWS) Capital One Financial CorpLead Data Engineer - Risk Tech (Python, AWS)Cambridge, MA$197,300–$225,100 / yearOur mission is divided into two primary functional pillars: Risk Management Tech (RMT), which develops the frameworks and tools for monitoring risks, testing controls, and managing regulatory requirements; and AML and Compliance Tech (ACT), which ensures our products are delivered ethically and in strict compliance with BSA/AML regulations and global laws. Share your passion for staying on top of tech trends, experimenting with and learning new technologies, participating in internal & external technology communities, and mentoring other members of the engineering community.
Senior Lead AI Engineer (GenAI Platform, Agentic Infrastructure) Capital One Financial CorpSenior Lead AI Engineer (GenAI Platform, Agentic Infrastructure)Cambridge, MA$229,900–$262,400 / yearBasic Qualifications: Bachelor's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 6 years of experience developing AI and ML algorithms or technologies, or a Master's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 4 years of experience developing AI and ML algorithms or technologies. In this role, you will: Partner with a cross-functional team of engineers, research scientists, technical program managers, and product managers to deliver AI-powered products that change how our associates work and how our customers interact with Capital One.
Lead AI Engineer (AI Foundations) Capital One Financial CorpLead AI Engineer (AI Foundations)Cambridge, MA$197,300–$225,100 / yearBasic Qualifications: Bachelor's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 4 years of experience developing AI and ML algorithms or technologies, or a Master's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 2 years of experience developing AI and ML algorithms or technologies. In this role, you will: Partner with a cross-functional team of engineers, research scientists, technical program managers, and product managers to deliver AI-powered products that change how our associates work and how our customers interact with Capital One.
Sr. Lead AI Engineer (FM Hosting, LLM Inference) Capital One Financial CorpSr. Lead AI Engineer (FM Hosting, LLM Inference)Cambridge, MA$229,900–$262,400 / yearBasic Qualifications: Bachelor's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 6 years of experience developing AI and ML algorithms or technologies, or a Master's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 4 years of experience developing AI and ML algorithms or technologies. In this role, you will: Partner with a cross-functional team of engineers, research scientists, technical program managers, and product managers to deliver AI-powered products that change how our associates work and how our customers interact with Capital One.
Senior Lead AI Engineer (GenAI Platform Services, Agentic Platform) Capital One Financial CorpSenior Lead AI Engineer (GenAI Platform Services, Agentic Platform)Cambridge, MA$229,900–$262,400 / yearBasic Qualifications: Bachelor's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 6 years of experience developing AI and ML algorithms or technologies, or a Master's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 4 years of experience developing AI and ML algorithms or technologies. In this role, you will: Partner with a cross-functional team of engineers, research scientists, technical program managers, and product managers to deliver AI-powered products that change how our associates work and how our customers interact with Capital One.
Senior Lead AI Engineer(MLX, Agentic AI, Gen AI platform Services) Capital One Financial CorpSenior Lead AI Engineer(MLX, Agentic AI, Gen AI platform Services)Cambridge, MA$229,900–$262,400 / yearBasic Qualifications: Bachelor's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 6 years of experience developing AI and ML algorithms or technologies, or a Master's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 4 years of experience developing AI and ML algorithms or technologies. In this role, you will: Partner with a cross-functional team of engineers, research scientists, technical program managers, and product managers to deliver AI-powered products that change how our associates work and how our customers interact with Capital One.
Lead AI Engineer (Gen AI Platform Services: Agentic AI, Agent Guardrails, Agent Evaluation, Agent Memory) Capital One Financial CorpLead AI Engineer (Gen AI Platform Services: Agentic AI, Agent Guardrails, Agent Evaluation, Agent Memory)Cambridge, MA$197,300–$225,100 / yearBasic Qualifications: Bachelor's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 4 years of experience developing AI and ML algorithms or technologies, or a Master's degree in Computer Science, AI, Electrical Engineering, Computer Engineering, or related fields plus at least 2 years of experience developing AI and ML algorithms or technologies. In this role, you will: Partner with a cross-functional team of engineers, research scientists, technical program managers, and product managers to deliver AI-powered products that change how our associates work and how our customers interact with Capital One.
Lead Software Engineer, Fullstack (Python, Typescript, React, AWS) Capital One Financial CorpLead Software Engineer, Fullstack (Python, Typescript, React, AWS)Cambridge, MA$197,300–$225,100 / yearOur mission is divided into two primary functional pillars: Risk Management Tech (RMT), which develops the frameworks and tools for monitoring risks, testing controls, and managing regulatory requirements; and AML and Compliance Tech (ACT), which ensures our products are delivered ethically and in strict compliance with BSA/AML regulations and global laws. Our Architecture team bridges the gap between business strategy and technical execution through a customer centric, domain oriented lens, while our Engineering Excellence team empowers our talent to build better, more resilient systems every day.