Required clinical skills include central line and peripheral line care, blood product administration, feeding tube care, surgical drain management, noninvasive ventilation, high-flow oxygen therapy, insulin administration, isolation precautions, intravenous therapy, and oxygen administration. Common patient conditions include heart failure exacerbation, pneumonia, chronic obstructive pulmonary disease exacerbation, acute hypoxia, gastrointestinal bleeding, bowel obstruction, pancreatitis, acute kidney injury, urinary tract infection, and electrolyte imbalance.