Research Leader / Senior Scientist (In vivo Pharmacology & Translational Sciences), Cambridge, MA Isomorphic LabsResearch Leader / Senior Scientist (In vivo Pharmacology & Translational Sciences), Cambridge, MACambridge, MAAct as a vital bridge between computational prediction and experimental reality, collaborating closely with: ML and Data Science Teams: To translate in silico predictions into physical validation protocols and provide clean data loops to train future models, iteratively improving the predictive accuracy of our proprietary drug design platform. These are exciting opportunities to work closely with world leading ML and drug discovery experts to develop imaginative new ways to test biological hypotheses, building a deep mechanistic understanding of drug target interactions in disease to drive our projects forward.
Research Leader / Senior Scientist (In Vivo Pharmacology & Translational Sciences), Cambridge, MA Isomorphic LabsResearch Leader / Senior Scientist (In Vivo Pharmacology & Translational Sciences), Cambridge, MACambridge, MAAct as a vital bridge between computational prediction and experimental reality, collaborating closely with: ML and Data Science Teams: To translate in silico predictions into physical validation protocols and provide clean data loops to train future models, iteratively improving the predictive accuracy of our proprietary drug design platform. Classification of protected categories is as follows: A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.
Metabolic Research and Dietary Assessment Unit Manager Tufts UniversityMetabolic Research and Dietary Assessment Unit ManagerBoston, MassachusettsStudy Management: Work with PIs, individual study teams, other core unit managers, and study MDs to design human nutrition research studies; with and via MRUDAU staff, operationalize IRB-approved study protocols (creating study budgets, MOPs, SOPs, study visit plans, etc.) and ensure successful, safe, on-time, on-budget completion of those protocols while ensuring adherence to regulations and best practices relating to data and biological sample collection. Assists PIs in developing core unit budgets sufficient to cover proposed core unit research activities, as all as provides operational, regulatory, budgetary, and content-based leadership of the unit, working closely with PIs, study teams, other HNRCA core unit managers, and MRUDAU staff on many aspects of study design, implementation, execution, and close-out.
NewSenior Director, DMPK Project Leader Centessa Pharmaceuticals, LLCSenior Director, DMPK Project LeaderBoston, MA$200,000–$215,000 / yearCentessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa's OX2R agonist portfolio includes additional clinical and preclinical-stage assets with potential utility across a broader range of neurological, neurodegenerative, and neuropsychiatric conditions.
Process Improvement and Education Manager, IRB Boston Children's HospitalProcess Improvement and Education Manager, IRBBoston, MA$105,102.40–$168,157.60 / yearKnowledge of HHS and FDA regulations, clinical research monitoring, data management and analysis, auditing principles and techniques, and experience developing and implementing process improvement initiatives, including benchmarks and metrics. Key Responsibilities: Under the Senior Director of Clinical Research Compliance, manages Process Improvement, regulatory policy, auditing, and Education efforts to ensure compliance with federal/state regulations and BCH policies protecting human subjects in clinical research.
NewSenior Director, DMPK Project Leader Centessa Pharmaceuticals PlcSenior Director, DMPK Project LeaderBoston, MA$200,000–$215,000 / yearCentessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa''s OX2R agonist portfolio includes additional clinical and preclinical-stage assets with potential utility across a broader range of neurological, neurodegenerative, and neuropsychiatric conditions.
NewSenior Director, Dmpk Project Leader Centessa Pharmaceuticals PlcSenior Director, Dmpk Project LeaderBoston, MA$200,000–$215,000 / yearCentessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa's OX2R agonist portfolio includes additional clinical and preclinical-stage assets with potential utility across a broader range of neurological, neurodegenerative, and neuropsychiatric conditions.
Program Manager Brigham and Women's HospitalProgram ManagerBoston, MA$63,648–$92,570.40 / yearThe Massachusetts General Hospital Ammon-Pinizzotto Center for Women's Mental Health (CWMH) provides clinical consultation and research regarding the course and treatment of psychiatric disorders during pregnancy and the postpartum period. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success.
Director, Head Of Program Management Tessera TherapeuticsDirector, Head Of Program ManagementSomerville, MA$186,000–$239,000 / yearGuiding and empowering Program Managers to drive the development and management of integrated program plans (including timelines, assumptions, scenarios, risks, critical path, decision maps, goals, and budget drivers). Company Summary: Tessera Therapeutics is pioneering Gene Writing- a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source.
Senior Director, DMPK Project Leader Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and CompanySenior Director, DMPK Project LeaderBoston, MA$200,000–$215,000 / yearCentessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa's OX2R agonist portfolio includes additional clinical and preclinical-stage assets with potential utility across a broader range of neurological, neurodegenerative, and neuropsychiatric conditions.
Program Manager, Research Lahey Hospital and Medical CenterProgram Manager, ResearchBoston, MA$65,000–$119,995.20 / yearMaintains daily correspondence (via email and phone) with all team members and external study/project sponsors in a professional and timely manner, archiving records of correspondence per NIH, FDA, and/or other applicable Federal, State, and local regulations. Actual compensation is determined based on several factors, that may include seniority, education, training, relevant experience, relevant certifications, geography of work location, job responsibilities, or other applicable factors permissible by law.
NewManager, Patient Safety Parexel International CorpManager, Patient SafetyMAWith 22,000+ employees worldwide, we partner with biopharmaceutical companies and research sites to design and deliver patient-focused clinical trials that broaden access and make research a care option for anyone, anywhere. Through team development, client partnership, cross-functional collaboration, and continuous improvement, you will help deliver high-quality safety services that are essential to clinical research and patient protection.
Principal Scientist (Director), Translational Medicine - Infectious Diseases Merck & Co IncPrincipal Scientist (Director), Translational Medicine - Infectious DiseasesBoston, MA$260,300–$409,700 / yearPrimary responsibilities for the Principal Scientist include the following: Working with basic science teams on specific diseases and therapeutic areas, providing clinical expertise for identification and validation of novel targets, including the design of preclinical and clinical experiments to validate targets and/or pathways, and leveraging this work for development of novel therapeutics. Translational Medicine is specifically responsible for: Contributing to the identification of novel targets by partnering with Discovery Sciences to bring a clinical perspective into the earliest stages of target identification and validation, and to execute clinical studies to evaluate the relevance of potential targets to human disease in order to justify full development.
Manager, Patient Safety ParexelManager, Patient SafetyMassachusettsWith 22,000+ employees worldwide, we partner with biopharmaceutical companies and research sites to design and deliver patient-focused clinical trials that broaden access and make research a care option for anyone, anywhere. Through team development, client partnership, cross-functional collaboration, and continuous improvement, you will help deliver high-quality safety services that are essential to clinical research and patient protection.
Program Manager Mass General BrighamProgram ManagerBoston, MassachusettsThe project includes an initial UG3 planning phase focused on protocol finalization, regulatory approvals, staff training, and site readiness, followed by a UH3 efficacy phase that will enroll 510 participants across five sites: Mass General Brigham, the University of Kentucky, Dell Medical School, Vanderbilt University, and Duke University. Be responsible for the day-to-day activities of assigning work projects, monitoring the progress of all project staff, and directly supervising and evaluating the work of the Project Coordinator and Clinical Research Coordinators (CRCs), including serving as back-up when needed.
Forward Deployed Product Manager - AI Iterative Scopes IncForward Deployed Product Manager - AICambridge, MA$170,000–$250,000 / yearWe built a leading performance-driven network of 100+ sites across the US, Europe, India, and Australia, conducting research directly in the communities where care is delivered across gastrointestinal, hepatology, obesity, and cardiology. By combining deep clinical trial expertise with cutting-edge AI, we connect sponsors'' scientific ambitions with high-performing research teams that expedite and expand access to novel therapeutics for patients in need.
Research Leader / Senior Scientist (In vitro / Cellular Pharmacology), Cambridge, MA Isomorphic LabsResearch Leader / Senior Scientist (In vitro / Cellular Pharmacology), Cambridge, MACambridge, MAThese roles are ideal for experienced in vitro pharmacologists with significant working knowledge of biophysical, biochemical and/or cell-based functional assays, and extensive experience of providing quantitative in vitro pharmacology expertise within drug discovery projects. These are exciting opportunities to work closely with world-leading ML and drug discovery experts to develop imaginative new ways to test biological hypotheses, building a deep mechanistic understanding of drug target interactions to drive our projects forward.
Research Leader / Senior Scientist (In Vitro / Cellular Pharmacology), Cambridge, MA Isomorphic LabsResearch Leader / Senior Scientist (In Vitro / Cellular Pharmacology), Cambridge, MACambridge, MAClassification of protected categories is as follows: A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability. These roles are ideal for experienced in vitro pharmacologists with significant working knowledge of biophysical, biochemical and/or cell-based functional assays, and extensive experience of providing quantitative in vitro pharmacology expertise within drug discovery projects.
Medical Monitor/Senior Medical Monitor, Hematology Tessera TherapeuticsMedical Monitor/Senior Medical Monitor, HematologySomerville, MA$270,000–$335,000 / yearMinimum 3 years of biotechnology or pharmaceutical industry experience in clinical development with direct experience serving as a Medical Monitor for interventional clinical studies, or extensive academic expertise as a Principal Investigator of hematology/oncology clinical trials with a demonstrated track record of publications. Reporting to the Chief Medical & Development Officer, the Medical Monitor will play a critical role in the design, conduct, and interpretation of early-stage clinical trials for novel genomic medicines targeting hematologic diseases, with indications that may include sickle cell disease and hematologic malignancies.
Research Program Manager I Brigham and Women's HospitalResearch Program Manager IBoston, MA$63,648–$92,570.40 / yearWorking closely with faculty, research administration, grants management, finance, clinical research teams, and institutional partners, the Program Manager ensures initiatives remain on track, removes operational barriers, and provides the structure and follow-through needed to execute program priorities. The role requires exceptional project management skills, strong organizational and communication abilities, experience managing complex cross-functional initiatives, and the ability to build productive relationships across multidisciplinary teams.