(Senior) Research Associate, Stem Cell Biology Conception Bio(Senior) Research Associate, Stem Cell BiologyBerkeley, CASupport cell banks and iPSC line quality control: Be a central player in making sure our iPSC line quality control is performed accurately and with care for both core and R&D lines, including mycoplasma and sterility testing and preparing samples for whole genome sequencing. This is an excellent opportunity for a junior scientist who follows protocols carefully, learns quickly from senior teammates, and enjoys adding value in the lab.
Research Associate II, Structural & Cellular Biology Proteomics & CryoET Chan Zuckerberg Biohub IncResearch Associate II, Structural & Cellular Biology Proteomics & CryoETRedwood City, CA$83,000–$103,000 / yearYou will maintain and engineer cell lines, design and optimize sample-preparation workflows for both mass spectrometry and cryoET, and help implement proximity labeling, crosslinking, correlative light and electron microscopy (CLEM), and FIB-SEM lamella preparation to map protein interaction networks and cellular architecture. This role sits at the interface of two closely connected efforts within our Dynamic Structural Biology group, which maps the molecular architecture of living cells - charting how protein complexes assemble, where they localize, and how their organization shifts across cell states and in response to perturbation.
Director, Virtual Biology Initiative Chan Zuckerberg Biohub IncDirector, Virtual Biology InitiativeRedwood City, CA$244,000–$305,000 / yearAs the director of the Virtual Biology Initiative, you will play a central role in building that ecosystem -- bringing together the organizations, partnerships, and long-term collaborations needed to accelerate a new era of AI-enabled biology. Working closely with scientific, technical, legal, and operational leaders, this leader will coordinate across disciplines to ensure partnerships advance VBI''s priorities and contribute to a cohesive, scalable ecosystem.
Director, High-Throughput Biology Eikon Therapeutics, Inc.Director, High-Throughput BiologyMillbrae, CA$213,000–$257,250 / yearThis role leads end-to-end high-throughput screening execution across automated and imaging-based platform technologies, ensuring delivery of scalable, reproducible, decision-enabling data that supports portfolio priorities. You are a strategic and technically grounded leader who brings deep expertise in high-throughput screening and platform biology, along with the ability to lead across biology, automation, and computational disciplines.
Director, Target Biology Revolution Medicines, Inc.Director, Target BiologyRedwood City, CA$211,000–$264,000 / yearWe are looking for an experienced drug hunter to lead the Target Biology team, provide hands-on scientific and people leadership, and work cross-functionally to identify and rapidly assess promising new targets, determine hit identification strategy, and advance screening hits through the early stages of hit-to-lead discovery. The company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.
Evolutionary Cell Biology Fellow Arcadia ScienceEvolutionary Cell Biology FellowEmeryville, CA$8,000–$12,000 / yearThis is an ideal opportunity for scientists in the final stages of their PhD or postdoc training who want to experience industry research in an open science environment working with diverse organisms, or for researchers excited to apply cell biology techniques across the tree of life. Because we use evolution to select the best organism to study each biological question, fellows will work with diverse, often non-traditional organisms and cell types.
Research Associate, Discovery Biology Assembly Biosciences IncResearch Associate, Discovery BiologySouth San Francisco, CA$87,000–$91,260 / yearDeveloping, optimizing, and validating biochemical and cell-based assays to support ongoing discovery projects In collaboration with senior research member, making detailed observations, analyzing data, and interpreting results Effectively supporting multiple projects and learning new techniques to support novel exploratory discovery work, as needed Presenting experimental findings, assay results, and scientific rationale clearly to internal project teams to support data-driven decision-making Utilizing data analysis software and MS Office applications Managing compound inventories and assay data Participating in general lab maintenance including reagent preparation, ordering of general lab supplies, and maintenance of equipment. Qualifications Include: Sc./M.S. or equivalent degree in Cell Biology, Molecular Biology, Virology, or relevant scientific discipline Minimum of two (2) years of relevant experience in industrial or academic settings, preference given to experience in a drug discovery setting Strong expertise in assay development, cell biology, virology, and molecular biology techniques, e.g.
Director, Target Biology Revolution Medicines IncDirector, Target BiologyRedwood City, CA$211,000–$264,000 / yearWe are looking for an experienced drug hunter to lead the Target Biology team, provide hands-on scientific and people leadership, and work cross-functionally to identify and rapidly assess promising new targets, determine hit identification strategy, and advance screening hits through the early stages of hit-to-lead discovery. The company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.
(Senior) Research Associate, Stem Cell Biology Conception(Senior) Research Associate, Stem Cell BiologyBerkeley, CaliforniaSupport cell banks and iPSC line quality control : Be a central player in making sure our iPSC line quality control is performed accurately and with care for both core and R&D lines, including mycoplasma and sterility testing and preparing samples for whole genome sequencing. This is an excellent opportunity for a junior scientist who follows protocols carefully, learns quickly from senior teammates, and enjoys adding value in the lab.
NewAI Biologist - Cancer Biology (Applications) LatchBioAI Biologist - Cancer Biology (Applications)San Francisco, CaliforniaExperience with hands on analysis of multi-omic tumor data hands-on somatic/germline variant calling and interpretation (WES/WGS/panel; MAF/VCF), copy-number and structural-variant analysis, mutational signatures, bulk and single-cell RNA-seq (cell-state annotation, subtyping), tumor-immune contexture (immune deconvolution, spatial transcriptomics, multiplex imaging), subclonal reconstruction, or functional-genomics screens (CRISPR/RNAi), or clinical research is highly preferred. Proficiency in Python and/or R: VCF/MAF parsing, single-cell analysis (Scanpy/Seurat), gene-set scoring (GSEA/ssGSEA), immune deconvolution (CIBERSORTx), subclonal reconstruction (PyClone), statistical analysis.
Member of Technical Staff, Experimental Biology Radical NumericsMember of Technical Staff, Experimental BiologySan Francisco, CaliforniaWe are looking for someone who can move fluidly between scientific strategy and execution: understanding what question we're trying to answer, designing the right experiment, getting it run quickly and rigorously, interpreting what happened, and turning the result into the next modeling or experimental decision. You'll design experiments to test ideas generated by our models, identify and manage the CROs and external laboratories that can execute them, interpret the resulting data, and work directly with our research teams to decide what to build next.
Associate Director, Cell Biology and Analytical Pathology Functional Team Lead; Enzymes and Metabolic Research Unit BioMarin Pharmaceutical IncAssociate Director, Cell Biology and Analytical Pathology Functional Team Lead; Enzymes and Metabolic Research UnitSan Rafael, CA$157,900–$217,140 / yearThe Enzymes and Metabolic Research group is seeking a highly motivated Associate Director with a strong background in pathology, image analysis, developing cellular models of disease and conducting preclinical translational research evaluating potential therapeutics for severe rare genetic diseases with unmet medical needs. Lead and inspire a high functioning team specialized in advanced analytical pathology techniques and developing cellular models of human disease to screen therapeutic compounds, evaluate mechanisms of action and identify therapeutic leads.
Research Operations Lead, Biology AnthropicResearch Operations Lead, BiologySan Francisco, CAManage vendor and supplier relationships: including contract research organizations: source and qualify vendors, negotiate quotes and service contracts, schedule preventive maintenance and field-service visits, and hold suppliers to their commitments. This research continues many of the directions our team worked on prior to Anthropic, including: GPT-3, Circuit-Based Interpretability, Multimodal Neurons, Scaling Laws, AI & Compute, Concrete Problems in AI Safety, and Learning from Human Preferences.
Senior Machine Learning Engineer, Agentic Science/Generative Models, AI for Biology & Translation (AIBT) Genentech IncSenior Machine Learning Engineer, Agentic Science/Generative Models, AI for Biology & Translation (AIBT)South San Francisco, CA$168,100–$312,300 / yearThe new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. Roche's Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact.
SPED Academic Tutor - Integrated Math 2, Biology & Study Skills Tutor Me EducationSPED Academic Tutor - Integrated Math 2, Biology & Study SkillsPacifica, CAAt Tutor Me Education, we are revolutionizing the way students learn, and we're seeking passionate teachers and tutors with special education experience to provide 1:1 in-home tutoring in Pacifica, CA ! You will be responsible for helping students with daily activities, offering moral support, and delivering tailored instruction based on their Individualized Education Plan (IEP).
Director, Small Molecule Discovery Biology (Inflammation & Autoimmunity) Alumis Inc.Director, Small Molecule Discovery Biology (Inflammation & Autoimmunity)San Francisco, CA$200,000–$240,000 / yearKey Responsibilities: Taking biology department responsibility in discovery-stage small molecule projects including conceptualizing project strategy, recognizing knowledge gaps, formulating screening paradigms, overseeing SAR generation, coordinating among project stakeholders, and identifying potential new targets. Overseeing development of both biochemical and cellular read-outs to support small molecule drug discovery efforts Support characterization of small molecule clinical candidates by employing autoimmune disease models and developing clinically relevant PD assays.
Scientist/Sr. Scientist, Chemical Biology General ProximityScientist/Sr. Scientist, Chemical BiologySan Francisco, MississippiYour responsibilities will include: supervising synthetic efforts with our CROs, designing, performing, and analyzing in cellulo assays, designing and optimizing first-in-class bifunctional molecules, collaborating with our Drug Discovery and IP team on patent applications, providing input for mechanistic studies on lead drug molecules, and spearheading forays into new disease areas. Experience with chemical biology techniques such as mammalian cell culture and cell-based assays (e.g., cytotoxicity assays, transfections, stable cell line generation, co-immunoprecipitation), and PPI assays (e.g., BRET, APEX/BioID, AlphaScreen).
Scientist / Senior Scientist, Structural Biology Amgen Inc.Scientist / Senior Scientist, Structural BiologySouth San Francisco, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. In this vital role you will help discovery teams tackle challenging mechanistic questions by developing practical structural biology strategies, enabling high-quality structural analysis, and delivering insights that support therapeutic program decisions.
Scientist, Mechanistic Biology General ProximityScientist, Mechanistic BiologySan Francisco, MississippiYour responsibilities will include designing and executing mechanistic studies on hit compounds, dissecting signaling pathways to map compound mechanism of action, interrogating protein-protein interactions, preparing and analyzing NGS libraries, and developing and deploying functional cell-based assays to characterize novel pharmacology. Strong experience with : Cellular and molecular biology, including extensive experience with mammalian cell line work and associated assays, stable cell line generation (lentiviral and CRISPR-based systems), co-IP/pull-down assays, RNA-seq, global proteomics, flow cytometry, plasmid design/cloning, etc.
Director, Small Molecule Discovery Biology Inflammation & Autoimmunity Alumis IncDirector, Small Molecule Discovery Biology Inflammation & AutoimmunitySan Francisco, CA$200,000–$240,000 / yearKey Responsibilities: Taking biology department responsibility in discovery-stage small molecule projects including conceptualizing project strategy, recognizing knowledge gaps, formulating screening paradigms, overseeing SAR generation, coordinating among project stakeholders, and identifying potential new targets. Overseeing development of both biochemical and cellular read-outs to support small molecule drug discovery efforts Support characterization of small molecule clinical candidates by employing autoimmune disease models and developing clinically relevant PD assays.