Associate Scientist, Oligonucleotide Chemistry & Delivery Denali TherapeuticsAssociate Scientist, Oligonucleotide Chemistry & DeliverySouth San Francisco, CA$106,000–$138,000 / yearSupport high-throughput and mid-scale oligonucleotide synthesis activities, including the evaluation of novel chemistries, modifications, and workflow innovations to enable rapid discovery-stage generation of siRNA/ASOs and bioconjugates within one or more preclinical drug discovery programs. Apply analytical technologies, including UV-Vis spectrophotometry, high-performance liquid chromatography (HPLC), mass spectrometry (MS), multi-angle light scattering (MALS), and other orthogonal characterization techniques, to analyze, purify, quantify, and characterize oligonucleotides and bioconjugates.
Part-Time Lecturer Pool - Oceanography & Natural Sciences (Chemistry, Physics and Oceanography) (AY 26/27) Cal PolyPart-Time Lecturer Pool - Oceanography & Natural Sciences (Chemistry, Physics and Oceanography) (AY 26/27)Vallejo, CaliforniaIn accordance with the California State University (CSU) Out-of-State Employment Policy, the CSU is a state entity whose business operations reside within the State of California and prohibits hiring employees to perform CSU related work outside of California. Sensitive positions are those requiring heightened scrutiny of individuals holding the position based on potential for harm to children, concerns for the safety and security of people, animals, or property, or heightened risk of financial loss to Cal Poly or individuals in the university community.
Bioconjugate & Surface-Chemistry Consultant Astera InstituteBioconjugate & Surface-Chemistry ConsultantEmeryville, CaliforniaUnlike traditional non-profit research organizations, projects supported by Astera operate like high-velocity startups, allowing us to focus on ambitious goals, match structure to problem, and attract strong technical talent and leadership. The Astera Institute is seeking a Bioconjugate & Surface-Chemistry Consultant to advise on and develop the surface chemistry that anchors a DNA-origami structure to a device surface with controlled placement and orientation.
Senior Scientist, Surface Chemistry Ultima GenomicsSenior Scientist, Surface ChemistryFremont, CA$120,000–$140,000 / yearThis role pays between $120,000 and $140,000, if performed in California, and your actual base pay will depend on your skills, qualifications, experience, and location. Experience with vapor-phase and CVD-style deposition of organosilanes, thiols, or related surface chemistries, biomaterials coatings and/or bioconjugation chemistry.
NewSenior Scientist, Peptide Chemistry (Night Shift) Capable LabsSenior Scientist, Peptide Chemistry (Night Shift)San Francisco, CaliforniaTroubleshoot synthetic and analytical issues during night-shift hours, including failed reactions, low conversion, low crude purity, side products, solubility limitations, cleavage/deprotection issues, purification challenges, and instrument downtime. Prepare compounds for in vitro and in vivo testing, maintain rigorous experimental records, and communicate overnight synthesis results, issues, timelines, and risks clearly to the day team.
NewAssociate Scientist, Organic Chemistry Capable LabsAssociate Scientist, Organic ChemistrySan Francisco, CaliforniaPurify and characterize compounds using analytical HPLC, prep HPLC, LC-MS, NMR, flash chromatography, SFC, and related methods; record identity, purity, yield, and batch-level QC data before handoff. Run solid-phase and solution-phase synthesis workflows where useful, including resin-based chemistry, coupling/deprotection cycles, cleavage, crude analysis, purification, and final compound QC.
NewVice President, Early Discovery Chemistry Revolution MedicinesVice President, Early Discovery ChemistryRedwood City, California$294,000–$367,000 / yearThe VP will foster close collaboration across biology, computational sciences, and downstream medicinal chemistry teams to ensure seamless progression from early discovery into lead optimization and contribute to advancing transformative science by demonstrating: Vision, strategy, leadership : Collaborate with Research leadership to develop a long-term strategy for portfolio expansion through discovery of inhibitors of frontier oncology targets. Innovation : Provide scientific leadership for innovation across early discovery and medicinal chemistry, leveraging advances in AI/ML, data-informed approaches to accelerate DMTA cycles, computational design, data analysis, automation, innovative synthesis and screening approaches, and data science to accelerate discovery and expand access to novel chemical space.
Scientist / Senior Scientist, Medicinal Chemistry Capable LabsScientist / Senior Scientist, Medicinal ChemistrySan Francisco, CaliforniaDesign and execute synthetic routes using solid-phase and solution-phase workflows, including functional group transformations, coupling chemistry, protecting group strategies, late-stage diversification, cleavage/deprotection where relevant, purification, and analytical characterization. Troubleshoot synthetic and analytical issues, including failed reactions, low conversion, poor selectivity, low crude purity, side products, solubility limitations, purification challenges, and instrument downtime.
Scientist / Senior Scientist, Organic Chemistry Capable LabsScientist / Senior Scientist, Organic ChemistrySan Francisco, CaliforniaDesign and execute synthetic routes using solid-phase and solution-phase workflows, including functional group transformations, coupling chemistry, protecting group strategies, late-stage diversification, cleavage and deprotection where relevant, purification, and analytical characterization. Troubleshoot synthetic and analytical issues with strong experimental judgment, including failed reactions, low conversion, poor selectivity, low crude purity, side products, solubility limitations, purification challenges, poor recovery, and instrument downtime.
Computational Chemistry / Theory Consultant Astera InstituteComputational Chemistry / Theory ConsultantEmeryville, CaliforniaThe Astera Institute is seeking a Computational Chemistry / Theory Consultant to provide the specialist molecular-simulation and theory for a nanoscale electrostatic actuator — the electrostatics that drive it and the mechanics of its moving parts (charged plate, force transmitter, and amplifying linkage) — and predict the experimental quantities the team measures on the bench. Model electrostatic actuation — how an applied field drives the charged DNA-origami plate through an ionic solution and into a polymer cushion — using appropriate methods (e.g., Poisson–Boltzmann, explicit-ion molecular dynamics, or continuum modeling) to predict the device's voltage–displacement and force behavior.
Director of Formulation Chemistry MonarchDirector of Formulation ChemistryOakland, CaliforniaThen applying computational chemistry and machine learning tools to predict which of the billions of potential compounds in nature trigger a ‘fly away’ signal from the olfactory neurons in the antennae to the smell center in the animal’s brain. Monarch is developing a product that works—a spatial repellent that protects crops from insects, humans from toxins, and insects from needless harm.
Chemistry Patent Agent (HYBRID) $120,000 $225,000 AmanwithaplanservicesChemistry Patent Agent (HYBRID) $120,000 $225,000San Francisco, CaliforniaLateral candidates only please, those coming directly from another LARGE FIRM Currently practicing in this same practice group. Expected hiring range for this position is $120,000 $225,000 per year depending on the candidates geographic market location.
Research Scientist - Computational Chemistry MonarchResearch Scientist - Computational ChemistryOakland, CaliforniaExperience with psi4, MDAnalysis, FreeSASA, AutoDock Vina, AutoDock 4. •Familiarity with cheminformatics tools (Open Babel, RDKit) and basic machine learning/AI applications in computational chemistry, including protein structure prediction (AlphaFold or similar). Then applying computational chemistry and machine learning tools to predict which of the billions of potential compounds in nature trigger a ‘fly away’ signal from the olfactory neurons in the antennae to the smell center in the animal’s brain.
Production Technician - Chemistry EarthOpticsProduction Technician - ChemistryEmeryville, CAOur mission is to be the leading soil information company, delivering maps that growers, farmers, ranchers, and other stakeholders use to cost-effectively increase yields and improve soil health and the climate. Collaborate with cross-functional lab teams (e.g., blending lab, carbon lab) to support overall lab operations and workflow efficiency.
NewAssociate Scientist, Peptide Chemistry (Night Shift) Capable LabsAssociate Scientist, Peptide Chemistry (Night Shift)San Francisco, CaliforniaRun microwave-assisted solid-phase peptide synthesis during night-shift hours, support routine synthesizer maintenance, and help troubleshoot failed couplings, low crude purity, side products, cleavage issues, and instrument downtime. You’re excited to own the overnight synthesis workflow: running reactions, purifying and characterizing compounds, documenting results, and preparing samples for testing with care and urgency.
Patent Attorney or Agent – Chemistry #22150 San Francisco Vanguard-IPPatent Attorney or Agent – Chemistry #22150 San FranciscoSan Francisco, CAOur sole focus on intellectual property enables us to more deeply understand our clients' technical needs, and our candidates' individual talents and career interests. • Candidates should possess an undergraduate degree and also an advanced degree in chemistry or related field, as well as experience with small molecules.
Patent Agent or Attorney – Chemistry #22150 San Francisco Vanguard-IPPatent Agent or Attorney – Chemistry #22150 San FranciscoSan Francisco, CAOur sole focus on intellectual property enables us to more deeply understand our clients' technical needs, and our candidates' individual talents and career interests. • Candidates should possess an undergraduate degree and preferably also an advanced degree in chemistry or related field, as well as experience with small molecules.
Senior Scientist, Oligonucleotide Design and Chemistry RD PartnersSenior Scientist, Oligonucleotide Design and ChemistrySouth San Francisco, California£130,832–£174,330In-depth knowledge of oligonucleotide/peptide therapeutics, including chemical structure search tools, synthesis techniques, purification instrumentation, and analysis methods for chemically modified oligonucleotides. R&D Partners is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe.
Associate Scientist, Peptide Chemistry Capable LabsAssociate Scientist, Peptide ChemistrySan Francisco, CaliforniaRun microwave-assisted solid-phase peptide synthesis, support routine synthesizer maintenance, and help troubleshoot failed couplings, low crude purity, side products, cleavage issues, and instrument downtime. Execute end-to-end peptide synthesis workflows, including resin loading, coupling and deprotection cycles, cleavage, purification, analytical characterization, and sample preparation for testing.
Associate Scientist, Organic Chemistry (Night Shift) Capable LabsAssociate Scientist, Organic Chemistry (Night Shift)San Francisco, CaliforniaRun microwave-assisted solid-phase peptide synthesis during night-shift hours, support routine synthesizer maintenance, and help troubleshoot failed couplings, low crude purity, side products, cleavage issues, and instrument downtime. You’re excited to own the overnight synthesis workflow: running reactions, purifying and characterizing compounds, documenting results, and preparing samples for testing with care and urgency.