research may include but is not limited to 1) developing, validating, improving and applying cell-based and other preclinical models to understand the functions of lipids, lipoproteins and related factors in influencing processes relevant to neurodegeneration, including neurovascular and inflammatory dysfunction; 2) designing and conducting mechanistic studies to characterize cellular responses to lipid and lipoprotein perturbations, including changes in gene expression, enzyme activities, cellular phenotypes, and metabolite production; and 3) performing statistical analyses of human clinical and/or omics data to evaluate human relevance of findings from preclinical models. dysfunction, or lipid metabolism; (ii) strong understanding of metabolism, including the roles of lipoprotein and lipid oxidation in the development and progression of chronic diseases; (iii) experience working with human clinical/omics data or preclinical animal models; (iv) strong statistical and computational analysis skills, including the use of bioinformatics tools or pipelines; and/or (v) experience with analytical platforms such as chromatography and mass spectrometry in omics research.