Awareness that PRN caregivers often serve as substitutes for a client's regular caregiver is critical , as clients may be hesitant, nervous, frustrated, or uncomfortable with someone new in their home, or may have dementia, memory loss, behavioral challenges, behavioral challenges, mental health conditions, or past trauma. Awareness that PRN caregivers often serve as substitutes for a client's regular caregiver is critical, as clients may be hesitant, nervous, frustrated, or uncomfortable with someone new in their home, or may have dementia, memory loss, behavioral challenges, behavioral challenges, mental health conditions, or past trauma.