NewAssociate Scientist #26-17074 US Tech Solutions, Inc.Associate Scientist #26-17074Thousand Oaks, CAThe role will work closely with a team of analysts and scientists responsible for the technical aspects of developing analytical tools to gain understanding of key quality attributes in product and process for late phase synthetic small molecule, synthetic oligonucleotide, synthetic peptide and/or antibody peptide conjugates. The Scientist will integrate and optimally utilize platform and in-depth product attribute knowledge to advance client’s products and ensure success through pivotal clinical phases to marketing authorization application.
Medicinal Chemist Inductive Bio IncMedicinal ChemistSan Francisco, CA$210,000–$250,000 / yearWe are seeking an accomplished Medicinal Chemist to play a key role in building an AI-forward drug discovery platform that impacts all stages of the Design-Make-Test-Analyze cycle, and deploy that platform to dozens of programs across the industry! Through partnerships with CROs, we also offer innovative synthesis approaches, direct-to-dose testing, and cost-effective tier 1 ADME panels that enable initial human PK projection, closing the loop from computational design to experimental validation.
Director or Associate Director, Medicinal Chemistry Allen SpoldenDirector or Associate Director, Medicinal ChemistryLa Jolla, CaliforniaThe role will entail coordinating a medicinal chemistry team with internal and external experimental capabilities, as well as proactively interfacing with diverse teams working on automated experimentation, AI -driven molecular generation, property predictions, and bioassay data generation. Devise strategies to identify lead molecules and optimize them for potency, selectivity, and ADME properties using multivariant SAR analysis and hypothesis driven design principles.
Director, Medicinal Chemistry Protagonist Therapeutics IncDirector, Medicinal ChemistryNewark, CA$210,000–$250,000 / yearThe Discovery Chemistry team at Protagonist Therapeutics is seeking a highly motivated and experienced Director of Medicinal Chemistry to lead and manage a competent chemistry group in small molecule and peptide drug discovery against a diverse range of therapeutic targets. The Company also has a number of preclinical stage drug discovery programs addressing clinically and commercially validated targets including an oral IL-17 peptide antagonist, obesity dual and triple agonists, an oral hepcidin functional mimetic, and the recently announced IL-4 and amylin programs.
Staff Scientist II - Medicinal Chemistry Protagonist Therapeutics IncStaff Scientist II - Medicinal ChemistryNewark, CA$135,000–$145,000 / yearThe Company also has a number of preclinical stage drug discovery programs addressing clinically and commercially validated targets including an oral IL-17 peptide antagonist, obesity dual and triple agonists, an oral hepcidin functional mimetic, and the recently announced IL-4 and amylin programs. The base pay range for this position at commencement of employment is expected to be between $135,000 and $145,000/year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.
Principal Scientist, Medicinal Chemistry Iambic TherapeuticsPrincipal Scientist, Medicinal ChemistrySan Diego, CaliforniaThe ideal candidate will be passionate about solving medicinal chemistry challenges, as well as proactively interfacing with diverse teams working on automated experimentation, AI-driven molecular generation, property predictions, and bioassay data generation. Execute on high quality ideas by employing a broad range of modern organic chemistry transformations, synthetic methods, creative use of parallel experimentations and implementing innovative techniques.
Principal Scientist, Medicinal Chemistry Neurocrine Biosciences IncPrincipal Scientist, Medicinal ChemistrySan Diego, CA$130,800–$179,000 / yearThe company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in patients with Prader-Willi syndrome, endometriosis and uterine fibroids , as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. Your Contributions (include, but are not limited to): Leads projects and initiatives in the rapid optimization of lead molecules utilizing modern technology available to medicinal chemists such as automated synthesis and purification.
Scientist, Medicinal Chemistry General ProximityScientist, Medicinal ChemistrySan Francisco, CAYour responsibilities will include designing and optimizing first-in-class bifunctional molecules, assessing SAR to inform iterative medicinal chemistry optimization, supervising synthetic efforts with CRO partners, performing and analyzing in cellulo assays, collaborating with our Drug Discovery and IP teams on patent applications, and contributing mechanistic insight on lead drug molecules. Chemical biology techniques including mammalian cell culture, cell-based assays (e.g., cytotoxicity, transfections, stable cell line generation, co-IP), and PPI assays (e.g., BRET, APEX/BioID, AlphaScreen); computational chemistry experience also welcomed.
Computational Scientist (Medicinal Chemistry) AxiomComputational Scientist (Medicinal Chemistry)San Francisco, CaliforniaThis creates a compounding loop: deeper customer understanding shapes the data we generate; better data improves frontier models, Axiom’s fine-tuned models, and our agentic infrastructure; stronger models and tooling expand the capabilities we can offer; and those capabilities are forward deployed into pharma's drug discovery workflows, where scientists use them to solve the highest value drug discovery problems. Influence active drug programs by helping teams understand whether toxicity risk is driven by exposure, potency, off-target biology, reactive metabolites, transporters, mitochondrial liability, cholestasis, immune mechanisms, or other drivers.
Director/Senior Director, Medicinal Chemistry Iambic TherapeuticsDirector/Senior Director, Medicinal ChemistrySan Diego, CaliforniaThe role will entail leading drug discovery projects, coordinating a medicinal chemistry team with internal and external experimental capabilities, as well as proactively interfacing with diverse teams working on automated experimentation, ML-driven molecular generation, property predictions, and bioassay data generation. We seek an accomplished and creative medicinal chemistry leader with a proven track record of success in advancing drug discovery programs, setting scientific strategy, and leading cross-functional teams to deliver impact.
Principal Scientist, Medicinal Chemistry Genentech IncPrincipal Scientist, Medicinal ChemistrySouth San Francisco, CA$144,000–$269,100 / yearIn addition to close collaboration with other chemists, the candidate will engage with various functions such as Drug Metabolism and Pharmacokinetics, Structural Biology, Biochemical and Cellular Pharmacology, Machine Learning, Pharmaceutical Sciences, Safety and disease area Biology. You will demonstrate extensive experience and record of accomplishment in one or more of the following areas: medicinal chemistry, methodology/catalysis, total synthesis, chemical biology and physical organic chemistry.
Scientist II/Senior Scientist, Medicinal Chemistry General ProximityScientist II/Senior Scientist, Medicinal ChemistrySan Francisco, CAYou will play a central role in molecular design of next generation IPMs, external execution, planning compound screening in routine biophysical or cellular assays and driving data interpretation, and scientific strategy, with the chance to make an outsized impact in a fast-moving startup environment. In this role, you will work at the intersection of chemistry, biology, and platform innovation, partnering closely with cross-functional teams to advance our core discovery capabilities and drive programs from concept through lead optimization.
Scientist/Sr. Scientist, Medicinal Chemistry General ProximityScientist/Sr. Scientist, Medicinal ChemistrySan Francisco, CAPROTACs or other IPMs)Contributing to hit-to-lead and lead optimization studiesMed-chem optimizations: SAR, PK/PD, strong understanding of DMPKApplicant must have experience with chemical biology techniques such as mammalian cell culture and cell-based assays (e.g., cytotoxicity assays, transfections, stable cell line generation, co-immunoprecipitation), PPI assays (e.g., BRET, APEX/BioID, AlphaScreen), or strong experience in computational chemistryNice to have:Proficiency in HTS and phenotypic assay developmentProteomics experience: PTM analysis, chemo-proteomic target deconvolution, etc. Your responsibilities will include: supervising synthetic efforts with our CROs, performing and analyzing in cellulo assays, designing and optimizing first-in-class bifunctional molecules, collaborating with our Drug Discovery and IP team on patent applications, providing input for mechanistic studies on lead drug molecules, and spearheading forays into new disease areas.
Sr Associate Scientist I or II, Medicinal Chemistry Iambic TherapeuticsSr Associate Scientist I or II, Medicinal ChemistrySan Diego, CaliforniaThis position offers the opportunity to work within a dynamic, cross-functional environment, collaborating closely with medicinal chemists, biologists, DMPK scientists, computational chemists, machine learning researchers, and software engineers throughout all stages of discovery, from hit identification and lead optimization through candidate selection. The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action.
Postdoctoral Scientist, Medicinal Chemistry Eli Lilly and CoPostdoctoral Scientist, Medicinal ChemistrySouth San Francisco, CA$58,000–$123,200 / yearOur current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL). Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve.
Postdoctoral Scholar - Research Associate - Chemist University of Southern CaliforniaPostdoctoral Scholar - Research Associate - ChemistLos Angeles, CADr. Yong (Tiger) Zhang's laboratory of the Department of Pharmacology & Pharmaceutical Sciences at USC Mann School of Pharmacy and Pharmaceutical Sciences is seeking a Postdoctoral Scholar - Research Associate to conduct research on protein post-translational modifications, antibody engineering, and preclinical design of chemotherapeutic and immunotherapeutic agents to treat cancer, immune disorders, and infectious diseases. When extending an offer of employment, the University of Southern California considers factors such as (but not limited to) the scope and responsibilities of the position, the candidate's work experience, education/training, key skills, internal peer equity, federal, state, and local laws, contractual stipulations, grant funding, as well as external market and organizational considerations.
Senior Computational Chemist Pfizer IncSenior Computational ChemistLa Jolla, CA$106,000–$176,600 / yearThe ideal candidate is expected to lead applied computational and cheminformatics efforts across project teams, develop and shape technical approaches across multiple initiatives, and contribute durable, reusable capabilities that strengthen MLCS platform infrastructure and influence how computational chemistry and cheminformatics is best practiced across Medicine Design. The Machine Learning & Computational Sciences (MLCS) organization within Medicine Design at Pfizer partners broadly across R&D to deliver computational, cheminformatics, and machine learning (ML) capabilities that accelerate drug discovery and development.
NewPrincipal Scientist - Medicinal Chemistry AmgenPrincipal Scientist - Medicinal ChemistryCaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Additional responsibilities may include advising supervisors and colleagues in areas of expertise; participating in national and international meetings, providing scientific results that support the generation of publications or patents, and mentoring research associates and laboratory assistants.
NewSenior Scientist (Organic Chemist-Oligonucleotide Delivery) AmgenSenior Scientist (Organic Chemist-Oligonucleotide Delivery)Thousand Oaks, CaliforniaIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. The chemist will be part of our oligonucleotide delivery team and utilize state-of-the-art methods to design and prepare novel delivery ligands, conjugation linkers, and nucleotides to chemically modify oligonucleotides for enhanced delivery and efficacy.
Scientist - Protein Engineering - Organic Chemist: ADC Research & Development Amgen IncScientist - Protein Engineering - Organic Chemist: ADC Research & DevelopmentThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Organic and Conjugation Chemist Amgen IncOrganic and Conjugation ChemistThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. The Hybrid Modality Group in the Complex Biologics & Strategic Tech Alliance Department of LMD & RDS at Amgen is seeking a highly motivated scientist in the field of chemical conjugation to join us in the state-of-the-art research facility at the Amgen headquarters campus located in Thousand Oaks, CA.
Principal Chemist LGC Biosearch TechnologiesPrincipal ChemistCAYou will serve as the technical lead for Oligonucleotide New Product Development (NPD), and Customer co‑creation product projects, designing new manufacturing methods, troubleshooting complex issues, supporting tech transfer, and presenting technical content to commercial teams and customers. Its high-quality product portfolio is comprised of mission-critical tools for genomic analysis and for quality assurance applications, which are typically embedded and recurring within our customers' products and workflows and are valued for their performance, quality, and range.
Paint & Coating Chemist WestcoatPaint & Coating ChemistSan Diego, CaliforniaAs a Paint & Coatings Chemist you will perform chemical and physical tests on existing and newly developed products, raw materials, and evaluate results to determine if products meet Westcoat specifications. The essential functions include, but are not limited to the following: Designing and implementing methods for process control, process improvement, testing, inspection to compliance, safety, and product/material specifications.
Principal Chemist LGC LtdPrincipal ChemistPetaluma, CAYou will serve as the technical lead for Oligonucleotide New Product Development (NPD), and Customer co‑creation product projects, designing new manufacturing methods, troubleshooting complex issues, supporting tech transfer, and presenting technical content to commercial teams and customers. Its high-quality product portfolio is comprised of mission-critical tools for genomic analysis and for quality assurance applications, which are typically embedded and recurring within our customers' products and workflows and are valued for their performance, quality, and range.
NewComputational Chemist - Generative Molecule & Protein Design F. Hoffmann-La Roche LtdComputational Chemist - Generative Molecule & Protein DesignSanta Clara, CA$145,300–$269,800 / yearD. Computational Chemistry, Biochemistry, Biophysics, Structural Biology, or a highly quantitative related field or a Master's degree in Computational Chemistry, Biochemistry with 2 years of related experience or Bachelors with 3 years of related experience. You will join an innovative, collaborative environment where you will: Drive Molecular & Protein Design: Build and run structure-based and ligand-based virtual screening workflows to find new substrates, cofactors, and small molecules for our sequencing and biocatalysis platforms.
Lead Synthesis Chemist PPGLead Synthesis ChemistBurbank, CaliforniaThrough leadership in innovation, sustainability and color, PPG helps customers in industrial, transportation, consumer products, and construction markets and aftermarkets to enhance more surfaces in more ways than does any other company. You will focus on hands-on synthetic work in the lab, process improvement for current manufacturing practices, and cross-team collaboration to develop new aerospace materials.
Lead Synthesis Chemist PPG Industries IncLead Synthesis ChemistBurbank, CAThrough leadership in innovation, sustainability and color, PPG helps customers in industrial, transportation, consumer products, and construction markets and aftermarkets to enhance more surfaces in more ways than does any other company. You will focus on hands-on synthetic work in the lab, process improvement for current manufacturing practices, and cross-team collaboration to develop new aerospace materials.
Senior E&L Chemist, Analytical Services Pacific Biolabs IncSenior E&L Chemist, Analytical ServicesHercules, CA$110,000–$140,000 / yearThe highly experienced and technically adept extractables and leachables chemist will lead efforts in identifying unknown peaks in complex samples using advanced Liquid Chromatography-Mass Spectrometry (LC/MS) techniques. Collaboration and communication: Work effectively with cross-functional teams, including other instrumentation groups, and quality assurance, to communicate findings, discuss results, and provide technical support related to unknown identification.
Head of Computational Chemistry General ProximityHead of Computational ChemistrySan Francisco, CAThis role will drive small-molecule drug discovery programs by providing strategic and practical modeling support, implementing modern computational workflows, and building the cheminformatics and AI-enabled infrastructure needed to empower medicinal chemists and project teams. The successful candidate will be both a scientific leader and a hands-on drug designer: someone who can partner closely with medicinal chemists, structural biologists, biologists, and DMPK scientists to guide compound design from hit identification through lead optimization and candidate selection.
Senior Scientist, Organic Chemistry - San Diego, CA DSM Nutritional Products Asia Pacific Pte LtdSenior Scientist, Organic Chemistry - San Diego, CASan Diego, CA$140,000–$170,000 / yearThe ideal candidate will be an accomplished synthetic organic chemist with a proven track record of conducting science-based and computer-aided discovery of new bioactive and/or bio-functional molecules. Partner cross-functionally with other internal Science and Research domains including Biology, Computational Science, AI, and Machine Learning teams to speed up discovery.
Senior Scientist / Principal Scientist - Process Chemistry Treeline Biosciences IncSenior Scientist / Principal Scientist - Process ChemistrySan Diego, CA$166,380–$189,533 / yearThe successful candidate will collaborate with cross-functional teams, including Medicinal Chemistry, DMPK, Toxicology, Drug Product, and Analytical Sciences to develop practical routes that support SAR exploration and deliver material for biological and early toxicology studies. Treeline Biosciences, a clinical-stage biotechnology company advancing precision medicines, is seeking an experiencedsmall molecule process chemistto drive the development, scale-up, andcommercialreadiness of oursmallmolecule, clinical-stageportfolio.
Senior Product Manager, Chemistry Revolution MedicinesSenior Product Manager, ChemistryRedwood City, CaliforniaYou will partner with medicinal chemists, synthetic chemists, computational chemists, analytical chemists, DMPK and Biology partners, Data Science, ML Engineering, Data Engineering, IT, and platform teams to turn complex Chemistry workflows into intuitive, scalable solutions that accelerate the Design-Make-Test-Learn cycle. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.
Senior Product Manager, Chemistry Revolution Medicines IncSenior Product Manager, ChemistryRedwood City, CA$186,000–$233,000 / yearYou will partner with medicinal chemists, synthetic chemists, computational chemists, analytical chemists, DMPK and Biology partners, Data Science, ML Engineering, Data Engineering, IT, and platform teams to turn complex Chemistry workflows into intuitive, scalable solutions that accelerate the Design-Make-Test-Learn cycle. The company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.
Scientist, Peptide Chemistry Calico Life Sciences LLCScientist, Peptide ChemistrySouth San Francisco, CA$135,000–$145,000 / yearInnovate Synthetic Workflows: Onboard and optimize novel chemistries for high-throughput, automated peptide synthesis; troubleshoot complex synthetic challenges to generate high-quality leads, and curate a custom library of building blocks. Calico's highly innovative technology labs, its commitment to curiosity-driven discovery science, and, with academic and industry partners, its vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs.
Staff Engineer, Chemical Search SatomicStaff Engineer, Chemical SearchSan Diego, California$180,000–$200,000 / yearYou will decide what to build versus buy on cheminformatics-specific tooling (RDKit / OpenEye for chemistry primitives, AiZynthFinder / ASKCOS / Synthia / IBM RXN for retrosynthesis, pharmacophore tooling, IP / FTO filtering, vector index choice), choose the engine's core representations, and define the versioning rules that keep it correct as chemistry capabilities expand. The intersection is rare by definition– we are looking for the person, not the perfectly formatted resume: Track record of owning a production chemistry search (or closely analogous retrieval / indexing system over structured scientific data) end-to-end in production, with real users on a customer-facing critical path.
Scientific Director, Computational Chemistry Neurocrine Biosciences IncScientific Director, Computational ChemistrySan Diego, CA$218,200–$298,000 / yearThe company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in patients with Prader-Willi syndrome, endometriosis and uterine fibroids , as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. Working within multidisciplinary teams of medicinal chemists, structural biologists, pharmacologists, data scientists, and ADME/Tox representatives, provides molecular-level insight and computational expertise to inform compound design, potency and selectivity optimization, and de-risk design hypotheses.
Principal Scientist, Analytical Chemistry Revolution Medicines IncPrincipal Scientist, Analytical ChemistryRedwood City, CA$190,000–$238,000 / yearThe company's RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. Design and implementation of discovery analytics, analytical data integration through collaboration with LabOS team, Data Sciences and Data Analytics functions to develop and implement automated high-throughput analytical methods that enhance efficiency and data quality.
Principal Scientist, Peptide Therapeutics Genentech IncPrincipal Scientist, Peptide TherapeuticsSouth San Francisco, CA$143,200–$265,900 / yearSynthetic Mastery: Utilize expert-level skills in solid-phase peptide synthesis, solution-phase organic chemistry, and specialized macrocyclization or ligation strategies. In this lab-based leadership role, you will combine hands-on synthetic expertise with strategic oversight, driving the discovery and optimization of peptide therapeutics across the full development lifecycle.
PT Instructor - Physical Science (Organic Chemistry) - Continuous Applicant Pool Santa Monica CollegePT Instructor - Physical Science (Organic Chemistry) - Continuous Applicant PoolSanta Monica, CA$52,762.50–$259,875 / yearEmployees who lose non-District-provided coverage as a result of divorce or death of a spouse shall be allowed to change their election; otherwise changes to election of Kaiser or dental or vision plans are limited to the open enrollment period. Demonstrated sensitivity to issues of diversity, and ability to motivate and teach community college students of diverse ethnic and racial backgrounds, sexual orientations, genders, cultures, and learning styles, as well as students with disabilities or varied levels of academic preparation.
Process Development Senior Scientist - Synthetic Peptides, Oligonucleotides, ADCs Amgen IncProcess Development Senior Scientist - Synthetic Peptides, Oligonucleotides, ADCsThousand Oaks, CAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Key Responsibilities: Work effectively with a diverse team of synthetic chemists, chemical engineers and analytical chemists to invent synthetic routes and develop safe, robust, sustainable and cost-effective processes for antibody drug conjugate, peptide antibody conjugates, synthetic peptides and/or oligonucleotide manufacturing.
Scientist, R&D Chemistry, Peptidomimetic Synthesis Regeneron PharmaceuticalsScientist, R&D Chemistry, Peptidomimetic SynthesisHawthorne, CaliforniaPerform medicinal chemistry inspired and SAR-driven synthesis of novel peptidomimetic drug modality payloads/linker payloads, using modern peptide synthesizer, isolation, and characterization instrumentation and techniques. Successful candidates will have a peptidomimetic/synthetic organic/medicinal chemistry background and will require peptidomimetic synthesis, discovery and SAR (structure-activity relationship) optimization expertise as well as linker-payload synthesis experience.
Senior Associate Scientist, R&D Chemistry Regeneron PharmaceuticalsSenior Associate Scientist, R&D ChemistryHawthorne, CaliforniaThe candidate will enable in-house laboratory-based synthetic chemistry activities towards the discovery and generation of novel small-molecule payloads and linkers for antibody-drug conjugate therapeutics across research areas of oncology, metabolic disease/obesity, infectious diseases, immunology and inflammation, neuroscience, and ophthalmology. Successful candidates will have small-molecule synthetic organic background and experience with the retrosynthetic analysis, synthetic route design, and hands-on execution of multistep synthetic protocols including compound isolation and characterization.
Research Assistant – Automated Organic Synthesis OnepotResearch Assistant – Automated Organic SynthesisSouth San Francisco, CaliforniaAutomated Synthesis Execution: Set up and run organic synthesis reactions using robotic liquid-handling systems (e.g., Opentrons OT-2), including sensitive reactions under inert conditions (glovebox, Schlenk lines) and photochemical reactions. Protocol & Software Development: Assist in writing and refining Python or Bash scripts for automating laboratory workflows, data parsing, plate mapping, and instrument control.
Lecturer Pool in Department of Chemistry & Biochemistry (Academic Year 26/27) Academic Year 26/27Lecturer Pool in Department of Chemistry & Biochemistry (Academic Year 26/27)CaliforniaCourses offered by the department include: General Chemistry, Inorganic Chemistry, Organic Chemistry, NMR Techniques, Molecular Modeling, Quantitative Analysis, Physical Chemistry, Earth Systems Chemistry, Biochemistry, and Selected Topics in Advanced Chemistry. Humboldt strives to build a supportive and inclusive Native community and engages with Native communities through initiatives and opportunities like the annual California Indian Big Time, Indigenous People's Week, and a chance to network with other faculty and staff as part of the Cal Poly Humboldt Council of American Indian Faculty and Staff.
Lecturer Pool in Department of Chemistry & Biochemistry (Academic Year 26/27) California State UniversityLecturer Pool in Department of Chemistry & Biochemistry (Academic Year 26/27)Arcata, CA$5,507–$6,677Courses offered by the department include: General Chemistry, Inorganic Chemistry, Organic Chemistry, NMR Techniques, Molecular Modeling, Quantitative Analysis, Physical Chemistry, Earth Systems Chemistry, Biochemistry, and Selected Topics in Advanced Chemistry. Humboldt strives to build a supportive and inclusive Native community and engages with Native communities through initiatives and opportunities like the annual California Indian Big Time, Indigenous People''''s Week, and a chance to network with other faculty and staff as part of the Cal Poly Humboldt Council of American Indian Faculty and Staff.
Lecturer Pool in Department of Chemistry & Biochemistry (Academic Year 26/27) CSU CareersLecturer Pool in Department of Chemistry & Biochemistry (Academic Year 26/27)CaliforniaCourses offered by the department include: General Chemistry, Inorganic Chemistry, Organic Chemistry, NMR Techniques, Molecular Modeling, Quantitative Analysis, Physical Chemistry, Earth Systems Chemistry, Biochemistry, and Selected Topics in Advanced Chemistry. Humboldt strives to build a supportive and inclusive Native community and engages with Native communities through initiatives and opportunities like the annual California Indian Big Time, Indigenous People's Week, and a chance to network with other faculty and staff as part of the Cal Poly Humboldt Council of American Indian Faculty and Staff.
Senior Principal Research Scientist, Computational Chemistry Ideaya Biosciences IncSenior Principal Research Scientist, Computational ChemistrySouth San Francisco, CA$196,000–$242,000 / yearAs part of the drug discovery team, the candidate will contribute directly to target assessment and druggability analysis, perform virtual screening and structure-based modeling, and work closely with medicinal chemists to design compounds with improved potency, selectivity, functional activity, and developability (e.g., ADME/DMPK). Along with our inspiring mission, and highly collaborative and inclusive environment, IDEAYA offers a competitive total rewards package that reflects our pay-for-performance philosophy where employees are eligible to be considered for merit-based salary increases, company discretionary short-term incentive plan participation, and company discretionary stock option awards (based on board approval).
Sr. Associate Scientist, R&D Chemistry, Peptidomimetic Purification Regeneron PharmaceuticalsSr. Associate Scientist, R&D Chemistry, Peptidomimetic PurificationHawthorne, CaliforniaThe R&D Chemistry team is primarily composed of synthetic organic, medicinal chemistry and bioconjugation scientists that work in a highly collaborative environment with other technology, biology and therapeutic area groups. We expect they will act as an inspiring and motivating colleague, effective communicator, and strong project team collaborator to help develop novel antibody-conjugated peptidomimetic therapeutics.
Staff / Senior Scientist, Assay Development (Chemistry) Glyphic BiotechnologiesStaff / Senior Scientist, Assay Development (Chemistry)Berkeley, CaliforniaReporting to the Director of Assay Development, you will be a hands-on expert working at the chemistry-assay interface — developing the chemical methods that enable reliable, high-efficiency sample loading into our expansion assay, and building the novel conjugation, cleavage, and stabilization workflows that power our single-molecule proteome sequencing platform. Demonstrated experience developing site-selective bioconjugation chemistry for native peptides — including N-terminal, C-terminal, and side-chain modification strategies — using click chemistry (CuAAC, SPAAC, IEDDA), NHS-ester coupling, and related bioorthogonal approaches in multi-component peptide systems.
Lecturer, Chemistry and Biochemistry DetailsLecturer, Chemistry and BiochemistrySan Diego, CaliforniaInstructors in the organic chemistry series are supported by our Director of Organic Chemistry who leads regularly scheduled meetings with lecture and laboratory instructors to communicate curricular content and maintain consistency across multi-section courses. Instructors in the general chemistry series are supported by our Director of General Chemistry who leads regularly scheduled meetings with lecture and laboratory instructors to communicate curricular content and maintain consistency across multi-section courses.