13 Results for

Medicinal Chemist Jobs in Massachusetts

Jobs

Watertown, MA30+ days ago

$145,000–$240,000 Per Year

PhD in organic/medicinal chemistry with 8+ years of experience or 10+ years of experience as a medicinal chemist/project leader in the biotech/pharmaceutical industry with a track-record of leading/contributing to research projects towards IND-track nomination. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions.

Cambridge, MA30+ days ago

$167,504–$226,624

You will be responsible for applying state-of-the-art medicinal and synthetic chemistry expertise to advance small-molecule drug discovery programs toward the clinic and provide support for existing programs in pre-clinical development. At Akebia we take that number very seriously and every day we come to work, with the purpose of bettering the lives of each person impacted by kidney disease and the renal community that serves them.

New!

Boston, MA3 days ago

$170,000–$220,000 Per Year

Project Management: Manage cross-functional CRO collaborations in a dynamic, sprint-based environment, focusing on the continuous refinement of DMTA workflows to rapidly advance drug discovery programs. You will advance our preclinical pipeline, targeting immune system dysfunction and chronic inflammation, by defining and executing medicinal chemistry strategies for multiple programs at the intersection of life sciences and computer science.

Cambridge, MA30+ days ago

$165,000–$200,000 Per Year

Its lead asset, zolucatetide (FOG-001), is a first-in-class, clinically validated direct inhibitor of the interaction between -catenin and the T-cell factor (TCF) family of transcription factors, implicated in millions of cancer cases annually, including in colorectal cancer, desmoid tumors, hepatocellular carcinoma and a range of other Wnt/-catenin-driven tumors. Develop, implement, and clearly communicate integrated synthesis strategies in partnership with Design, Data Science, De Novo Discovery, Molecular & Cellular Biology, DMPK, and Pharmacology teams to achieve hit-to-lead and lead optimization milestones.

Boston, MA30+ days ago

Strong understanding of key concepts, including potential energy surfaces (PES), intermolecular and intramolecular forces/interactions, force fields, molecular properties, thermodynamic properties, solvation models (implicit/explicit), and conformational sampling . We are the only AI-native biotech, pioneering small and large molecule therapeutics discovery by integrating massive multimodal data, frontier AI models, and high-throughput lab automation into an infrastructure for AI-enabled drug discovery.

Boston, MA30+ days ago

New!

Lexington, MA3 days ago

$116,400–$140,000 Per Year

These capabilities are applied to missions spanning chemical, biological, and explosives (CBE) detection and attribution; medical diagnostics and countermeasures; pathogen identification; point-of-care diagnostics; molecular intelligence; biosecurity; biomanufacturing, DNA forensics, and additive manufacturing. These projects include development of sensing materials for detecting chemicals and proteins, supporting analysis and down-stream processing of bio-manufactured materials, trace detection of threat chemicals, and the synthesis and formulation of small molecules and polymers.

Newburyport, MA30+ days ago

$66,000–$90,000 Per Year

Experience working with products that may pose special hazards, such as air-sensitive, moisture-sensitive, pyrophoric, high-energy, toxic, high-potency, etc., as well as synthetic organic, organometallic, or inorganic chemistries and associated equipment and techniques (e.g., glove boxes, Schlenk techniques). Performs routine chemical productions and process developments based on provided work instructions and training in a safe and high-quality manner.

MARLBOROUGH, MA30+ days ago

Technical Experience: Experience with general laboratory techniques such as reaction set-ups, precipitation, filtration, Schlenk techniques, distillation, closed transfer, crystallization, rotary evaporators, and vacuum pumps/ovens. Safety Oriented: Demonstrates safe behavior in the laboratory with a demonstrated ability to evaluate safety risks and reactivity concerns in multigram scale multi-step organic synthesis.

Waltham, MA27 days ago

$183,000–$223,000 Per Year
Full-time

Experience working in close collaboration with technical, regulatory, quality, clinical, project management, and supply chain functions, in a cGMP operational environmentExperience in leading and managing outsourced development and manufacturing efforts and associated operating budgetsExperience in preparing and defending regulatory documents including briefing books for regulatory meetingsDemonstrated track record of setting priorities, meeting timelines and motivating othersExcellent communication skills and the ability to shape, frame, and present to diverse internal and external audiences are requiredPeriodic travel to manufacturing and other partner sites is required (approximately 10-20 % of time)The anticipated annualized base pay range for this full-time position is $183,000 - $223,000 Ardelyx utilizes industry data to ensure that our compensation is competitive and aligned with our industry peers. Own DS program execution including development plans and timelinesCMO selection, RFP development, and technical evaluationOversight of tech transfer, scale-up, and GMP manufacturingContribute to and review CMC sections of regulatory filings and support health authority interactions.

Cambridge, MA30+ days ago

Full-time

The Scientist, is part of Analytical Development Starting Material Group and will be responsible for Develop, qualify and transfer GC, HPLC, UPLC and mass spectrometry based assays of starting materials, raw materials, intermediates and excipients to suppliers, CMOs and QC. Author and review method development and qualification reports and SOPs for test methods, as well as transfer / qualification protocols and reports related to critical starting materials / intermediates / excipients.

New!

Milton, MA4 days ago

$50,000–$120,000 Per Year

Actively participate in greater community enrichment activities, such as advising a student activity, acting as a faculty sponsor to a student club, coaching an athletic team, leading an intramural sport or acting as an affinity group advisor. This position involves instructing courses in chemistry and potentially biology, providing students with inquiry-based experiences across the life and physical sciences at all levels (regular, honors, and advanced).

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Medicinal Chemist Jobs in Massachusetts

Jobs

Principal Scientist or Associate Director, Medicinal ChemistryKymera Therapeutics

Principal, Medicinal ChemistryAkebia Therapeutics

Principal Scientist & Program Lead, Medicinal ChemistryDeepCure

Associate Director, Medicinal Chemistry - SynthesisParabilis Medicines

Computational Theoretical Chemist III1910

Computational Theoretical Chemist I1910

Computational Theoretical Chemist II1910

ChemistMIT Lincoln Laboratory

Production ChemistAscensus Specialties

Laboratory TechnicianTechDigital

Associate Director, Process Chemistry (CMC)Ardelyx

Clinical/Development - Scientist, Analytical DevelopmentLanceSoft Inc

Upper School Science Teacher - Biology & ChemistryMilton Academy

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