NewSenior Director, AIRx Medicinal Chemistry Takeda PharmaceuticalSenior Director, AIRx Medicinal ChemistryBoston, MA$212,000–$333,190 / yearThe actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. Takeda Research is constructing the Discovery Automation & Robotics (DAR) group built on AI, automation, new ways of working, and talent with the singular vision of delivering differentiated medicines to the clinic at speed and cost.
Medicinal Chemist Inductive Bio IncMedicinal ChemistBoston, MA$210,000–$250,000 / yearWe are seeking an accomplished Medicinal Chemist to play a key role in building an AI-forward drug discovery platform that impacts all stages of the Design-Make-Test-Analyze cycle, and deploy that platform to dozens of programs across the industry! Through partnerships with CROs, we also offer innovative synthesis approaches, direct-to-dose testing, and cost-effective tier 1 ADME panels that enable initial human PK projection, closing the loop from computational design to experimental validation.
Computational Medicinal Chemist Novartis AGComputational Medicinal ChemistCambridge, MA$126,000–$234,000 / yearInternal Job Title: Senior Expert I/II, Data SciencePosition Location: San Diego, CA, hybridYour Responsibilities Include:Drive the design of medicinal chemistry efforts by applying in-depth knowledge of structure-activity relationships (SAR), structure-based and ligand-based drug design, a profound understanding of target biology, and predictive methods for assessing on- and off-target activity, physical properties, pharmacokinetics/pharmacodynamics (PK/PD), and synthetic feasibility. Thrive at the intersection of experimental and groundbreaking digital technologies, with a particular emphasis on expertise in machine learning, active learning and physics-based CADD methodologies as applied to small molecule drug discovery as well as in the induced proximity space.
Research Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MA Isomorphic LabsResearch Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MACambridge, MAProven track record of project leadership / leading medicinal chemistry efforts on drug discovery projects, demonstrating significant contributions to project progression (ideally from hit identification through to lead optimisation or candidate nomination), with familiarity of optimisation of ADME properties. Rapidly drive drug discovery programs to value inflection points by deploying your knowledge of modern discovery principles and synthetic organic chemistry, taking ownership as either an overall Project Lead or Medicinal Chemistry Lead.
Research Leader / Senior Scientist Medicinal Drug Design, Cambridge, MA Isomorphic Labs LimitedResearch Leader / Senior Scientist Medicinal Drug Design, Cambridge, MACambridge, MAProven track record of project leadership / leading medicinal chemistry efforts on drug discovery projects, demonstrating significant contributions to project progression (ideally from hit identification through to lead optimisation or candidate nomination), with familiarity of optimisation of ADME properties. Rapidly drive drug discovery programs to value inflection points by deploying your knowledge of modern discovery principles and synthetic organic chemistry, taking ownership as either an overall Project Lead or Medicinal Chemistry Lead.
NewSenior Director, AIRx Medicinal Chemistry 3316 Takeda Development Center AmericasSenior Director, AIRx Medicinal ChemistryBoston, MassachusettsThe actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. Takeda Research is constructing the Discovery Automation & Robotics (DAR) group built on AI, automation, new ways of working, and talent with the singular vision of delivering differentiated medicines to the clinic at speed and cost.
Principal Scientist, Medicinal Chemistry Psivant TherapeuticsPrincipal Scientist, Medicinal ChemistryWatertown, Massachusetts$170,000–$200,000 / yearThe role requires practical experience designing and synthesizing complex molecules, peptides and peptidomimetics; applying structure-activity relationship principles to improve potency, selectivity, stability, permeability, and ADME/PK properties; and using multiparameter optimization to balance efficacy, developability, and oral exposure. Appointable candidates will also have experience directing chemistry CRO, leading teams and communicating decisions clearly to cross-functional teams to progress programs efficiently toward development candidates.
NewComputational Synthetic Chemist Ginkgo BioworksComputational Synthetic ChemistBoston, MA$115,000–$165,000 / yearIndependent route-design judgment under real constraints on materials, time, building blocks, and execution resources, supported by a broad synthetic-organic reaction toolkit and strong purification and characterization skills. Design, select, and execute practical multi-step routes to novel drug-like singleton compounds and focused sets under real constraints on time, materials, building blocks, and available resources.
NewComputational Synthetic Chemist Ginkgo BioWorks IncComputational Synthetic ChemistBoston, MA$115,000–$165,000 / yearIndependent route-design judgment under real constraints on materials, time, building blocks, and execution resources, supported by a broad synthetic-organic reaction toolkit and strong purification and characterization skills. Design, select, and execute practical multi-step routes to novel drug-like singleton compounds and focused sets under real constraints on time, materials, building blocks, and available resources.
NewComputational Chemist ProximaComputational ChemistBoston, MANeo-1 enables rapid exploration of chemical and structural space for high value, previously intractable targets, and in particular unlocks small molecule proximity therapeutics like molecular glues with AI for the first time. Proximity-based therapeutics represent one of most promising frontiers in modern drug discovery with the potential to treat previously intractable diseases and target 'undruggable' proteins.
Product Scientist (Computational Chemist) Inductive Bio IncProduct Scientist (Computational Chemist)Boston, MA$180,000–$220,000 / yearYou'll also be a thought leader in the development of Inductive's platform, from our predictive models and dose projection tools to Indy, our AI medicinal chemistry assistant, informed by your own experience and what you see working (and not working) on real partner programs. Model in vivo outcomes end to end, from PK/PD/efficacy relationships to projected human dose, helping teams evaluate compounds through a dose-centric lens and reason about property tradeoffs in the context of therapeutic window.
Computational Theoretical Chemist III 1910Computational Theoretical Chemist IIIBoston, MassachusettsStrong understanding of key concepts, including potential energy surfaces (PES), intermolecular and intramolecular forces/interactions, force fields, molecular properties, thermodynamic properties, solvation models (implicit/explicit), and conformational sampling. We are the only AI-native biotech, pioneering small and large molecule therapeutics discovery by integrating massive multimodal data, frontier AI models, and high-throughput lab automation into an infrastructure for AI-enabled drug discovery.
Computational Theoretical Chemist II 1910Computational Theoretical Chemist IIBoston, MAStrong understanding of key concepts, including potential energy surfaces (PES), intermolecular and intramolecular forces/interactions, force fields, molecular properties, thermodynamic properties, solvation models (implicit/explicit), and conformational sampling. We are the only AI-native biotech, pioneering small and large molecule therapeutics discovery by integrating massive multimodal data, frontier AI models, and high-throughput lab automation into an infrastructure for AI-enabled drug discovery.
Computational Theoretical Chemist I 1910Computational Theoretical Chemist IBoston, MAStrong understanding of key concepts, including potential energy surfaces (PES), intermolecular and intramolecular forces/interactions, force fields, molecular properties, thermodynamic properties, solvation models (implicit/explicit), and conformational sampling. We are the only AI-native biotech, pioneering small and large molecule therapeutics discovery by integrating massive multimodal data, frontier AI models, and high-throughput lab automation into an infrastructure for AI-enabled drug discovery.
2027 Spring - Co-Op Medicinal Chemistry, Cambridge, MA Sanofi2027 Spring - Co-Op Medicinal Chemistry, Cambridge, MACambridge, MA$29–$35 / hourWe are seeking an undergraduate chemistry major to execute synthetic routes for target compounds/drug candidates for approximately 6 months; the successful candidate will further develop synthetic organic chemistry skills in the lab, develop analytical and instrument techniques, learn medicinal chemistry, and gain further understanding of the drug discovery process by participating in an industrial medicinal chemistry department. Students currently on CPT, OPT, or STEM OPT usually require future sponsorship for long term employment and do not meet the Internal requirements for this program unless eligible for an alternative long-term status that does not require company sponsorship.
2027 Spring - Co-op Medicinal Chemistry, Cambridge, MA Sanofi2027 Spring - Co-op Medicinal Chemistry, Cambridge, MACambridge, MA$29–$35 / hourWe are seeking an undergraduate chemistry major to execute synthetic routes for target compounds/drug candidates for approximately 6 months; the successful candidate will further develop synthetic organic chemistry skills in the lab, develop analytical and instrument techniques, learn medicinal chemistry, and gain further understanding of the drug discovery process by participating in an industrial medicinal chemistry department. Students currently on CPT, OPT, or STEM OPT usually require future sponsorship for long term employment and do not meet the Internal requirements for this program unless eligible for an alternative long-term status that does not require company sponsorship.
Senior Organic Chemist Adiabatic MaterialsSenior Organic ChemistSomerville, MassachusettsElectrochemical Steps: Learn the cell and mediator chemistry hands-on with our Director of Electrochemical Engineering, run the electrochemical step as one step among multiple, and help expand the reaction scope. Working closely with our Chief Scientific Officer, you’ll identify and validate new reaction classes, devise routes that take advantage of our chemistry, and turn those ideas into robust experimental results.
Associate Chemist Revvity IncAssociate ChemistHopkinton, MA$50,500–$60,000 / yearUtilizing traditional synthetic chemical techniques, the scientist will execute routine chemical procedures involving solid state chemistry, wet chemistry, organic chemistry, inorganic chemistry, HPLC, analytical analysis for the production and analysis of chemical compounds. Support general lab functions, maintenance of equipment, product quality, packaging, on-time delivery of products, ensure cleanliness of workplace and good general laboratory techniques.
Kilolab Chemist SEQENS SASKilolab ChemistMASEQENS - Kilolab Chemist H/F EN FR SEQENS Careers website: All vacancies Follow us * Home Submit speculative application Searches, alerts Who we are ? Log in Candidate area I already have a candidate area Log in to candidate area : Required fields * Username (email address) Password Remember me Forgotten password? Create cand...
NewOrganic Chemist LancesoftOrganic ChemistCambridge, MASuccess in Client thrives on strong interpersonal and practical chemistry skills combined with an excitement for science. Develop and optimize new DNA compatible reactions that can be employed in the production of DNA-encoded libraries.