Executive Director, Biostatistics Vertex PharmaceuticalsExecutive Director, BiostatisticsBoston, MassachusettsOutstanding communication including clarity in writing including excellence in scientific/technical/process writing, influential speech and negotiation, ability to explain complex concepts to others, willingness and ability to engage in scientific discourse at the executive level. •Own statistical support in the therapeutic areas and/or Global Medical Affairs he/she leads including early/late clinical developments, post-marketing studies, RWE studies and/or analyses supporting reimbursement.
Director, Biostatistics Vertex Pharmaceuticals, IncDirector, BiostatisticsBoston, MA$204,000–$306,000 / yearGeneral Summary: The Director, Biostatistics will independently perform highly scientific statistical functions in support of the company's Global Medicines Development and Affairs (GMDA) area on new and complex issues. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Biostatistics Director (Hybrid) Vertex Pharmaceuticals, IncBiostatistics Director (Hybrid)Boston, MA$201,200–$301,800 / yearGeneral Summary: The Director, Biostatistics will independently perform highly scientific statistical functions in support of the company's Global Medicines Development and Affairs (GMDA) area on new and complex issues. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.
Sr. Director, Biostatistics Atavistik BioSr. Director, BiostatisticsCambridge, MAAtavistik Bio is led by an experienced team of drug hunters with a proven track record of developing marketed small molecule therapies and supported by top-tier investors, including The Column Group, Nextech Invest, Lux Capital, Regeneron Ventures, and RA Capital Management. Oversee and lead the vendor/CRO biostatistics and programming teams, including activities during TFL development, Data Monitoring Safety Board meetings, interim analyses, and database locks.
Associate Director, Biostatistics Pepgen IncAssociate Director, BiostatisticsBoston, MA$205,000–$236,000 / yearProvide input to help optimize trial designs for pivotal registrational studies; maintain strong competencies in statistical methodology and trial designs, particularly in therapeutic areas such as neuromuscular diseases or other rare diseases, with familiarity with ICH, FDA, and EMA guidelines. The Associate Director will serve as a statistical subject-matter expert on our cross-functional team, contributing to protocol development, study design, statistical analysis, regulatory submissions, publications and presentations, as well as supporting the management of CRO and external vendors.
Associate Director, Biostatistics Les Laboratoires Servier SASAssociate Director, BiostatisticsBoston, MARemote$164,000–$194,000 / yearProvide statistical support on one or more assets or indications by directing the execution of statistical analyses, review of statistical outputs, and ensuring accurate results interpretation, collaborating closely with physicians, evidence generation stakeholders, or other cross-functional leads as appropriate on the interpretation of clinical results. Provide guidance to the clinical, regulatory, and/or evidence generation teams on conclusions and inferences from the data package, ensuring statistical perspective is integrated into regulatory and external meetings, and delivering data packages aligned with submission requirements or key decision-making.
Senior Director Biostatistics Head of Statistical Innovation & Methodology Alnylam Pharmaceuticals IncSenior Director Biostatistics Head of Statistical Innovation & MethodologyMAMentor statisticians, promote knowledge sharing, and, as the function grows, build and lead a statistical innovation and methodology team to strengthen methodological expertise and foster a culture of statistical innovation within the Biostatistics organization. Engage externally with scientific organizations, regulatory agencies, and academic collaborators to contribute to methodological advancement, inform industry best practices, and ensure awareness of emerging statistical approaches.
Director Biostatistics Alnylam Pharmaceuticals IncDirector BiostatisticsCambridge, MACollaborates with Clinical Development, Regulatory and Clinical Operations Expertise Areas to design innovative clinical trials Authors the statistical sections of clinical trial protocols and statistical analysis plans Reviews and approves stratification/randomization schema Collaborates with Data Management, Clinical Development and Clinical Operations on design of eCRFs Provides statistical guidance on conduct of ongoing trials Collaborates with Statistical Programmers on summary and analysis of trial data. Leads biostatistics support for worldwide regulatory submissions Represents Alnylam in meetings with regulators, Key Opinion Leaders, partners, and other stakeholders Contributes to scientific articles, summarizing data collected in Alnylam trials Consults with Research, Preclinical, Clinical Pharmacology, Medical Affairs and Commercial colleagues on statistical questions in their work Responsible for timeline management across their clinical development program Ph.
Director, Biostatistics Bicara TherapeuticsDirector, BiostatisticsBoston, MassachusettsFICERA specifically addresses a key challenge in solid tumor treatment by enabling immune cell penetration into tumors, reducing fibrosis and immunosuppression while reversing TGF--driven resistance mechanisms - ultimately designed to drive the deep, durable responses that may translate into better outcomes and survival for patients. Founded in 2020, we've built a global team of over 100 employees headquartered in Boston, with a clear focus on advancing our lead asset, ficerafusp alfa, or FICERA - a potentially first-in-class bifunctional EGFR-directed antibody combined with a TGF- ligand trap.
Senior Director, Biostatistics Dyne Therapeutics IncSenior Director, BiostatisticsWaltham, MA$250,000–$290,000 / yearAs a senior statistical leader and cross-functional partner, this role leads statistical activities across the drug development lifecycle, including protocol development, authoring of statistical sections of protocols, development of statistical analysis plans, oversight of statistical analyses and deliverables, interpretation and communication of clinical trial results, and preparation of clinical study reports, regulatory documents, manuscripts, and scientific presentations. The Senior Director provides statistical leadership for global regulatory submissions and health authority interactions, ensuring that clinical development programs are supported by scientifically rigorous, operationally feasible, and innovative statistical strategies aligned with program and corporate objectives.
Global Head of Biostatistics GenentechGlobal Head of BiostatisticsBoston, MassachusettsAs the Global Head of Biostatistics, you will provide strategic leadership and oversight across all Therapeutic Area (TA)-aligned Biostatistics teams, ensuring a cohesive and high-performing Biostatistics function that drives excellence in service of our strategy through study design, data analysis, and insights generation. Act as the primary liaison between the Biostatistics function and key stakeholders across Clinical, Regulatory, and Data Science teams to drive alignment and shape outcomes for shared objectives; connect key stakeholders with therapeutic area Biostatistics Leaders as nuanced questions arise.
Senior Director, Biostatistics Zenas BioPharma (USA) LLCSenior Director, BiostatisticsWaltham, MA$227,400–$284,256 / yearZenas' earlier stage programs include ZB021, a clinical-stage, potentially best-in-class, oral, IL-17AA/AF inhibitor; ZB022, a preclinical, potentially best-in-class, oral, brain-penetrant, TYK2 inhibitor; and ZB014, a preclinical half-life extended anti-CD-19 and FcRIIb monoclonal antibody. Key Responsibilities: Set biostatistical strategy for one or more clinical development programs, including clinical development plans, contribution to study trial design, analysis planning, study results presentation and interpretation, clinical study report authoring, regulatory submissions, and publications.
Director, Biostatistics Amylyx PharmaceuticalsDirector, BiostatisticsCambridge, MARemote$221,000–$249,000 / yearOversee and/or contribute to key statistical deliverables, including protocols, statistical analysis plans, table/listing/figure shells, clinical study reports, integrated summaries of safety and efficacy, briefing documents, regulatory responses, and submission materials. Lead the design and oversight of robust, innovative clinical trial designs that maximize probability of clinical and regulatory success, balancing scientific rigor with operational feasibility, while anticipating and proactively addressing potential regulatory challenges.
Director, Biostatistics Amylyx Pharmaceuticals IncDirector, BiostatisticsCambridge, MARemote$221,000–$249,000 / yearOversee and/or contribute to key statistical deliverables, including protocols, statistical analysis plans, table/listing/figure shells, clinical study reports, integrated summaries of safety and efficacy, briefing documents, regulatory responses, and submission materials. Lead the design and oversight of robust, innovative clinical trial designs that maximize probability of clinical and regulatory success, balancing scientific rigor with operational feasibility, while anticipating and proactively addressing potential regulatory challenges.
Senior Director, Biostatistics Zenas BioPharmaSenior Director, BiostatisticsWaltham, MA$227,400–$284,256 / yearZenas' earlier stage programs include ZB021, a clinical-stage, potentially best-in-class, oral, IL-17AA/AF inhibitor; ZB022, a preclinical, potentially best-in-class, oral, brain-penetrant, TYK2 inhibitor; and ZB014, a preclinical half-life extended anti-CD-19 and FcRIIb monoclonal antibody. Key Responsibilities: Set biostatistical strategy for one or more clinical development programs, including clinical development plans, contribution to study trial design, analysis planning, study results presentation and interpretation, clinical study report authoring, regulatory submissions, and publications.
Associate Director, Biostatistics Bristol-Myers Squibb CoAssociate Director, BiostatisticsCambridge, MA$218,120–$264,308 / yearBased on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Lead Biostatistician (Interventional Cardiology and Vascular Research) Beth Israel Lahey HealthLead Biostatistician (Interventional Cardiology and Vascular Research)Boston, Massachusetts$95,000–$145,000 / yearAdditional preferred qualifications include SAS Base and Advanced certification, hands-on experience working with SAS (Base, Stat, Macro, SQL), experience mentoring other statisticians and trainees in statistical methods, and expertise in at least one of the following areas: causal inference, longitudinal analysis, or weighting methods. Smith Center for Outcomes Research (bidmc.org)) is devoted to addressing the most pressing issues in cardiovascular care through innovative and rigorous analysis of diverse data sources, including large national registries, administrative claims data, survey-based data, and EHR data.
Lead Biostatistician (Interventional Cardiology and Vascular Research) Lahey Hospital and Medical CenterLead Biostatistician (Interventional Cardiology and Vascular Research)Boston, MA$95,000–$145,000 / yearAdditional preferred qualifications include SAS Base and Advanced certification, hands-on experience working with SAS (Base, Stat, Macro, SQL), experience mentoring other statisticians and trainees in statistical methods, and expertise in at least one of the following areas: causal inference, longitudinal analysis, or weighting methods. Smith Center for Outcomes Research (bidmc.org)) is devoted to addressing the most pressing issues in cardiovascular care through innovative and rigorous analysis of diverse data sources, including large national registries, administrative claims data, survey-based data, and EHR data.
Biostatistician, Regulatory Submissions Analysis Group, Inc.Biostatistician, Regulatory SubmissionsBoston, Massachusetts$210,000–$255,000 / yearExcellent judgement, problem-solving, and communication skills, with the ability to translate complex technical concepts into clear, structured insights for clients While prior consulting experience is not required, candidates should demonstrate strong potential for client-facing work and structured problem solving. We have also been recognized as a best place to work in several top surveys, including national surveys by Glassdoor (Best Places to Work, Employees’ Choice Award, small and medium business category) and Vault (17th overall in the Vault Consulting 50, and the top-ranked economic consulting firm).
Biostatistician II Foundation Medicine IncBiostatistician IIMARemote$125,040–$156,300 / yearThis role builds and maintains strong collaborations with other departments across the organization to drive biostatistical strategy for evidence generation across diagnostics, clinical trials and real-world data (RWD/RWE) studies, develop statistical methodologies and models, write study protocols, conduct statistical analyses, write study reports, present responses to statistical and study design questions arising from regulatory authorities or external partners (e.g., academic or Biopharma collaborators), represent FMI at meetings with regulatory agencies such as the Food and Drug Administration, contribute to scientific publications, and/or work with internal and external partners for the development, validation, and regulatory approval of FMI's diagnostic assays in oncology and beyond. Lead and execute the design and data analysis of analytical and clinical validation studies on novel next generation sequencing (NGS)-based diagnostic devices for oncology and beyond, including but not limited to protocol development, statistical analysis plans and reports, and data reporting.