Global HR Business Partner - BioPharma R&D Clinical Operations AstraZeneca PlcGlobal HR Business Partner - BioPharma R&D Clinical OperationsBoston, MA$172,347.20–$258,520.80 / yearSignificant HR experience (8+ years) leading strategic HR, organizational transformation, workforce planning, and business change initiatives within large, sophisticated, and matrixed global organizations, preferably as a Global HR Business Partner or in another senior HR leadership role. Lead the end-to-end people and organizational strategy for BioPharma R&D Clinical Operations, shaping workforce transformation, organization capability, succession, talent strategies, and future-ready operating models aligned to evolving business priorities.
Director, Clinical Operations Excellence Relay Therapeutics, Inc.Director, Clinical Operations ExcellenceCambridge, MA$163,000–$233,000 / yearIn a lean, matrixed biotechnology environment, this role will serve as both a strategic leader and hands-on contributor, partnering with study teams, functional stakeholders, CROs, and vendors to strengthen execution, simplify processes, develop actionable operational metrics and analytics, and proactively manage operational and quality risks. Vendor Oversight and Governance: Support execution of the vendor governance strategy by organizing and facilitating governance forums, tracking decisions and actions, supporting performance oversight, issue escalation, corrective action follow-up, quality trend review, and RBQM operationalization.
Director, Clinical Operations Excellence Relay TherapeuticsDirector, Clinical Operations ExcellenceCambridge, MA$163,000–$233,000 / yearIn a lean, matrixed biotechnology environment, this role will serve as both a strategic leader and hands-on contributor, partnering with study teams, functional stakeholders, CROs, and vendors to strengthen execution, simplify processes, develop actionable operational metrics and analytics, and proactively manage operational and quality risks. Vendor Oversight and Governance: Support execution of the vendor governance strategy by organizing and facilitating governance forums, tracking decisions and actions, supporting performance oversight, issue escalation, corrective action follow-up, quality trend review, and RBQM operationalization.
Director, Clinical Operations Oruka Therapeutics, Inc.Director, Clinical OperationsWaltham, MA$213,000–$240,000 / yearSignificant experience with cross-functional leadership and clinical teams, including leading data review, protocol deviation review, database lock, CSR development, and study reporting activities. Role Overview: We are seeking an exceptionally nimble and flexible Director of Clinical Operations who has a track record of achievement across all aspects of trial setup and execution in a fast paced small biotech with limited infrastructure and resources.
Associate Director, Clinical Operations Clinical Dynamix, Inc.Associate Director, Clinical OperationsWatertown, MAWork closely with translational medicine team to ensure appropriate incorporation of bioanalytical sampling plan into clinical protocols and relevant data output of the trial is provided to functional groups for review. Provide study-specific training and leadership to clinical research staff, CRO, CRAs, sites and other contract personnel.
Contract Clinical Operations Lead Integrated Resources, IncContract Clinical Operations LeadCambridge, MassachusettsContractorRequired skill sets to include: proficiency in Microsoft Excel and Word, basic understanding and skills in legal contracts, organizational skills, effective communicator and adept at learning new systems. This person will directly assist with small value contract execution as required and will need to engage and collaborate with the business to understand business needs and expectations in order to accurately set up contracts and establish fair market value pricing.
Associate Director Clinical Operations Alnylam Pharmaceuticals IncAssociate Director Clinical OperationsCambridge, MAThe Associate Director, Site and Monitoring Health Team Lead will line manage and matrix manage Site and Monitoring Health Regional Leads (SMH Regional Leads) and direct the work of FSP Site and Monitoring Health Leads. Responsibilities: The Associate Director, Site and Monitoring Health Team Lead will provide strong leadership, GCP expertise and clinical operations experience to drive the monitoring strategy for trials in their assigned program(s).
Senior Director, Clinical Operations Alira HealthSenior Director, Clinical OperationsBoston, MassachusettsThe Senior Director, Clinical Operations provides oversight of Clinical Development Operations, Nonclinical Development, Regulatory Affairs, Quality Assurance, Manufacturing/CMC Operations, and Program Management, while partnering closely with R&D, Finance, Investor Relations, Legal, and the CEO to ensure efficient execution of corporate objectives. This role is accountable for translating the clinical operations strategy into operational execution, driving cross-functional alignment, ensuring compliance with global regulatory requirements, maintaining operational excellence, and supporting the advancement of the Company's development pipeline from research through commercialization.
Clinical Operations Leader Gates FoundationClinical Operations LeaderCambridge, MassachusettsThe COL will be responsible for ensuring that operational plans are developed to execute clinical studies and deliver quality data through all clinical trial phases across all programs in their assigned portfolio in accordance with the protocol, in compliance with ethical and regulatory requirements and in accordance with company SOPs, GCP and ICH guidelines within timelines and on budget. The successful candidate will be an innovative and collaborative individual who thrives in a “get it done” type of environment with diverse clinical operations experience and the following mix of personal and professional characteristics: 15+ years experience of Clinical Operations experience at biotechnology or pharmaceutical company or CRO, with at least 5+ years of people management.
Senior Director, Clinical Operations Kymera Therapeutics IncSenior Director, Clinical OperationsWatertown, MA$235,000–$330,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. How you'll make an impact: The Senior Director, Clinical Operations is a leadership role responsible for overseeing and managing all aspects of clinical operations for the Phase 3 program of a high priority immunology program, KT-621.
Product Marketing Manager / Senior Manager - Clinical Operations Veeva SystemsProduct Marketing Manager / Senior Manager - Clinical OperationsBoston, MA$75,000–$150,000 / yearUnlike a traditional corporation, whose only legal duty is to maximize shareholder value, PBCs consider their public benefit purpose and the interests of those materially affected by the corporation's conduct-including customers, employees, and the community-in addition to shareholders' interests. We're not just any public company - we made history in 2021 by becoming a public benefit corporation (PBC), legally bound to balancing the interests of customers, employees, society, and investors.
NewDirector, Pharmaceutical Sciences Clinical Manufacturing Business Operations 3316 Takeda Development Center AmericasDirector, Pharmaceutical Sciences Clinical Manufacturing Business OperationsLexington, MassachusettsProvide team leadership to ensure 1) PharmSci business processes are operating smoothly (CapEx, OpEx, Governance), 2) partner with Procurement to deliver year-over-years savings targets, and 3) support PharmSci in the development of SOWs, contracts and any additional purchasing support. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.
NewSenior Manager, Clinical Business Operations Relay Therapeutics IncSenior Manager, Clinical Business OperationsCambridge, MA$124,000–$177,000 / yearYou will work with the clinical study leads and cross-functional teams to establish governance process, which may include joint oversight committees, with key clinical vendors to monitor service levels and key performance indicators and manage issue escalation and resolution. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology.
Senior Manager, Clinical Operations - FSP Resource & Vendor Management CSL PlasmaSenior Manager, Clinical Operations - FSP Resource & Vendor ManagementWaltham, Pennsylvania$170,000–$201,000 / yearThe Senior Manager, Clinical Operations FSP Resource & Vendor Management sits within the Clinical Operations organization and is accountable for the end‑to‑end oversight, planning, and optimization of FSP resources supporting Clinical Operations functions. The role serves as the primary Clinical Operations interface to FSP vendors and works in close partnership with the POE organization, which retains accountability for enterprise‑level contracting, sourcing strategy, and overall vendor governance.
Executive Director, Clinical Business Operations Kura Oncology, Inc.Executive Director, Clinical Business OperationsBoston, MA$294,250–$340,832 / yearKura developed and is commercializing KOMZIFTI (ziftomenib), the FDA-approved once-daily, oral menin inhibitor for the treatment of adults with relapsed or refractory NPM1-mutated acute myeloid leukemia, and continues to pioneer advancements in menin inhibition and farnesyl transferase inhibition. ESSENTIAL JOB FUNCTIONS: The Executive Director, Clinical Business Operations serves as a strategic leader responsible for driving operational strategy, organizational effectiveness, portfolio governance, and business performance across the Clinical Operations organization.
Executive Director, Clinical Business Operations Kura OncologyExecutive Director, Clinical Business OperationsBoston, MA$294,250–$340,832 / yearKura developed and is commercializing KOMZIFTI® (ziftomenib), the FDA-approved once-daily, oral menin inhibitor for the treatment of adults with relapsed or refractory NPM1-mutated acute myeloid leukemia, and continues to pioneer advancements in menin inhibition and farnesyl transferase inhibition. Kura Oncology is a commercial-stage biopharmaceutical company committed to discovering and developing innovative precision medicines to help patients with cancer lead better, longer lives.
Senior Product Manager - Veeva Clinical Operations Veeva SystemsSenior Product Manager - Veeva Clinical OperationsBoston, MA$120,000–$200,000 / yearUnlike a traditional corporation, whose only legal duty is to maximize shareholder value, PBCs consider their public benefit purpose and the interests of those materially affected by the corporation's conduct-including customers, employees, and the community-in addition to shareholders' interests. We're not just any public company - we made history in 2021 by becoming a public benefit corporation (PBC), legally bound to balancing the interests of customers, employees, society, and investors.
Senior Manager, Clinical Laboratory Operations Zenas BioPharmaSenior Manager, Clinical Laboratory OperationsWaltham, MA$134,500–$168,228 / yearOversee and manage external laboratories, CROs, central labs, specialty testing vendors, sample storage vendors, and other clinical trial service providers, including identification, qualification, onboarding, performance management, issue resolution, review of scopes of work, budgets, contracts, laboratory capabilities, operational risks, and adherence to contractual scope, budget, and timelines. Zenas' earlier stage programs include ZB021, a clinical-stage, potentially best-in-class, oral, IL-17AA/AF inhibitor; ZB022, a preclinical, potentially best-in-class, oral, brain-penetrant, TYK2 inhibitor; and ZB014, a preclinical half-life extended anti-CD-19 and FcRIIb monoclonal antibody.
Director, Clinical Operations Oruka Therapeutics IncDirector, Clinical OperationsWaltham, MA$213,000–$240,000 / yearSignificant experience with cross-functional leadership and clinical teams, including leading data review, protocol deviation review, database lock, CSR development, and study reporting activities. Role Overview: We are seeking an exceptionally nimble and flexible Director of Clinical Operations who has a track record of achievement across all aspects of trial setup and execution in a fast paced small biotech with limited infrastructure and resources.
Associate Director, Clinical Operations Kymera Therapeutics IncAssociate Director, Clinical OperationsWatertown, MA$160,000–$240,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Work closely with translational medicine team to ensure appropriate incorporation of bioanalytical sampling plan into clinical protocols and relevant data output of the trial is provided to functional groups for review.