Principal Architect, Security Architecture Cencora, Inc.Principal Architect, Security ArchitectureWilmington, DE$110,500–$220,990 / yearThe Principal Architect- Cybersecurity works horizontally across the functional technology domains and the related security practices for Cloud, Infrastructure, Endpoint, Network, Storage; while also collaborating and representing core cybersecurity practices such as Identity & Access Management, Application Security, Data Security, AI Security, Cyber Defense, SaaS Security, OT/IoT, and emerging technologies, ensuring that security capabilities function as an integrated enterprise architecture rather than independent controls. Summary: The Principal Architect, Security Architecture is a senior individual-contributor and enterprise technical leadership role responsible for defining, governing, and advancing cybersecurity architecture across the enterprise in collaboration with other Principal Architects, Cybersecurity Architects, & Cybersecurity and domain engineering teams.
Principal Financial Analyst - Medicine Finance Penn MedicinePrincipal Financial Analyst - Medicine FinancePhiladelphia, PAThe Principal Financial Analyst communicates complex concepts in a clear manner with managers and senior leadership within the department, as well as other corporate departments (A/P, Purchasing, Finance, Capital Accounting). Penn Medicine is dedicated to our tripartite mission of providing the highest level of care to patients, conducting innovative research, and educating future leaders in the field of medicine.
Special Projects Group Principal Geotechnical Engineer - Transportation ECS LtdSpecial Projects Group Principal Geotechnical Engineer - TransportationMount Laurel, New Jersey$125,000–$200,000 / yearECS is currently ranked #60 in Engineering News-Record’s Top 500 Design Firms (April 2026), #148 in Engineering News-Record’s Top 200 Environmental Firms (October 2025) and #38 in Zweig Group’s Hot Firm List (June 2026). Primary responsibilities include pursuit and execution of geotechnical projects in the transportation sector in the northern Mid-Atlantic region , including highway, bridge, and rai l .
Principal Controls Engineer- Data Center Barry-WehmillerPrincipal Controls Engineer- Data CenterKing Of Prussia, PA$150,000–$220,000 / yearMinimum of 15 years of progressive engineering experience in building automation, electrical power monitoring systems (EPMS), and integrated controls within mission-critical environments-especially data centers-including significant leadership and client-facing responsibilities. Design Group is widely known as an industry leader, recognized as a top system integrator, ranking #9 in the 2025 System Integrator Giants; as a Rockwell Platinum Integrator, the highest designation given to Rockwell partners; and as an Ignition Enterprise Premier Integrator.
Principal Civil Engineer Barry-WehmillerPrincipal Civil EngineerKing Of Prussia, PA$170,000–$240,000 / yearBy blending people-centric leadership with disciplined operational strategies and purpose-driven growth, Barry-Wehmiller has become a $3 billion organization with nearly 12,000 team members united by a common belief: to use the power of business to build a better world. Rooted in our distinct culture of Truly Human Leadership, we cultivate the leaders who will define tomorrow and partner with our clients in the food & beverage, life sciences, industrial, and advanced technology industries to build the future of manufacturing and technology.
Associate Principal, Commercial Strategy Trinity Life SciencesAssociate Principal, Commercial StrategyEast Norriton, PA$156,000–$234,000 / yearTrinity's salary bands account for a wide range of factors that are considered in making compensation decisions including but not limited to skill sets and market demand for skills; level of experience and training; specific qualifications, performance, time in role/company, geographic location, and other business and organizational needs. For more than 30 years, the world's leading pharmaceutical, biotech, and medtech companies have relied on Trinity's foresight, execution, and partnership to deliver confident product launches, decisive market advantage, and measurable patient impact.
Principal Security Engineer StratAcuity Staffing Partners IncPrincipal Security EngineerPhiladelphia, PA$55–$60 / hourIn terms of professional development, Everforth Apex hosts an on-demand training program, provides access to certification prep and a library of technical and leadership courses/books/seminars once you have 6+ months of tenure, and certification discounts and other perks to associations that include CompTIA and IIBA. This includes an understanding of encryption methodologies, network architecture, protocols, and security technologies (firewalls, IDS/IPS, VPN, SIEM, endpoint protection), and proficiency in security frameworks like MITRE ATT&CK and the Cyber Kill Chain.
NewPrincipal Clinical Content- Physician - UpToDate, Physician Editor, Adult Rheumatology Wolters Kluwer N.V.Principal Clinical Content- Physician - UpToDate, Physician Editor, Adult RheumatologyPhiladelphia, PA$173,500–$310,000 / yearUpToDate editors work closely with outside authors, section editors, editors-in-chief, and peer reviewers to ensure the material is accurate and free of bias. In the remaining 10 to 20% time, most Physician Editors remain involved in patient care activities, using their clinical experience to help ensure the content of the program is maximally useful at the point of care.
Principal Scientist, Biologics Optimization Johnson & JohnsonPrincipal Scientist, Biologics OptimizationSpring House, PAPurpose: The Biologics Optimization team within Biologics Discovery is responsible for the design and optimization of lead biologic variants across multiple therapeutic modalities to achieve differentiated functional outcomes aligned with desired therapeutic mechanism of action (MoA). The Principal Scientist will be expected to establish and champion scientific best practices in function-driven optimization, leveraging detailed understanding of antibody structure-function relationships, protein sequence space, and biological pathways to guide engineering decisions.
Principal Scientist (Director) - Outcomes Research Merck & Co IncPrincipal Scientist (Director) - Outcomes ResearchNorth Wales, PA$190,800–$300,300 / yearPrimary Responsibilities: This position has primary responsibility for planning/managing a comprehensive program of real-world evidence and non-interventional research activities for in-line and pipeline products for lung cancers to meet the value evidence needs of clinicians, payers, policymakers, health technology assessment (HTA)/reimbursement agencies, and health systems globally. The following skills and knowledge are needed to be successful in this role: Decision making: Identifying and understanding problems and opportunities by gathering, analyzing and interpreting quantitative and qualitative information; choosing the best course of action by establishing clear decision criteria, generating and evaluating alternatives, and making timely decisions; taking action that is consistent with available facts and constraints and optimizes probable consequences.
(Sr.) (Lead) (Principal) Energy Analyst/Engineer (II) PJM Interconnection LLC(Sr.) (Lead) (Principal) Energy Analyst/Engineer (II)PALead) Analyst/Engineer will support the Capacity Market Operations Department to successfully manage the $12 billion per year PJM Capacity Market that is used to ensure the reliability of the PJM system. The candidate will also help with the financial analysis of default minimum offer prices, default maximum offer prices, reference resource price used to determine the demand curve and power plant estimated net revenues.
Principal Scientist (Scientific Director Level)- Nonclinical Drug Safety Merck & Co IncPrincipal Scientist (Scientific Director Level)- Nonclinical Drug SafetyWest Point, PA$176,200–$277,300 / yearThey are responsible for 1) providing risk assessments for targets, 2) de-risking strategies for discovery programs and 3) collaborating with NDS staff at other sites to execute on the appropriate studies to support selection of therapeutic targets, and the identification and development of new drug candidates. The Discovery Program Leader is responsible for defining and overseeing the NDS strategy for programs in all modalities (including small molecules, peptides, biologics and ADC programs) from Target Identification through to the approval of First-In-Human enabling GLP toxicity studies.
Principal Scientist, Drug Product Steriles Primary Packaging GSK plcPrincipal Scientist, Drug Product Steriles Primary PackagingCollegeville, PADrug Delivery, External Manufacturing, Medical Device Evaluation, Molecular Modeling, Pharmaceutical Formulations, Pharmacokinetics, Product Design, Product Management, Product Planning, Product Strategies, Quality by Design, Regulatory Filings, Stability Testing, Technology Transfer. Formulation Product Development: Understanding of actives, raw materials and their function and how they are brought together to form a stable, functioning product from prototype evaluation to commercial launch Job Family - Product Development: Manages or contributes to development of the company's products.
Associate Principal Scientist, Statistical Programming, Late-Stage Oncology (Hybrid) Merck & Co IncAssociate Principal Scientist, Statistical Programming, Late-Stage Oncology (Hybrid)North Wales, PA$142,400–$224,100 / yearIn BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our Company's renowned Research and Development division, quantitative scientists, in partnership with other subject matter experts, apply state-of-the art scientific methodologies and tools to enable the discovery, development, regulatory approval, manufacturing, and marketing of medical drugs and vaccines for the benefit of patients and global human health. Required Skills: Base SAS, Clinical Development, Data Management, Data Modeling, FDA Submissions, Influencing Skills, Oncology, Presentation Delivery, Process Improvements, Project Management, Project Planning, Resource Planning, Stakeholder Management, Statistical Programming, Strategic Planning, Strategic Thinking.
Principal Engineer (US) Qurate Retail Group, Inc.Principal Engineer (US)PAQVC Group, Inc. is a Fortune 500 company with six leading retail brands - QVC, HSN, Ballard Designs, Frontgate, Garnet Hill and Grandin Road. If provided, salary ranges are a general guideline only, and actual salaries will vary and are based on factors such as a candidate's qualifications, skills, experience, and geographic location as well as business and market conditions.
Experienced Structural Engineer | Associate Principal Wiss Janney Elstner AssociatesExperienced Structural Engineer | Associate PrincipalPhiladelphia, Pennsylvania$110,700–$184,500 / yearTechnical leadership, including applying sound engineering judgement and a deep understanding of governing codes, design guidelines, and industry practices; collaborating with interdisciplinary project teams across WJE as the structural engineering subject-matter expert (SME); leveraging your expertise for a variety of structural engineering projects, including the investigation, design, analysis, repair, and renovation of new and existing structures, construction materials, loading conditions, and construction types; preparing technically excellent client deliverables; providing high-quality reviews and oversight of work by others; and performing and training others in hands-on fieldwork. Minimum twenty years of relevant structural engineering industry experience, including technical and project management (e.g., failure/damage investigation; non-destructive evaluation and instrumentation; structural analysis and design for repair, retrofit, and rehabilitation of existing structures; evaluation of parking garage structures; and/or specialty consulting of new systems and materials from design through construction).
Associate Principal Scientist/Engineer, Medical Device and Combination Products, Analytical Merck & Co IncAssociate Principal Scientist/Engineer, Medical Device and Combination Products, AnalyticalWest Point, PA$142,400–$224,100 / yearRequired Skills: Analytical Chemistry, Computed Tomography (CT), Cross-Cultural Awareness, Design Validations, Design Verification, Design Verification Testing, Device Characterization, Interdisciplinary Collaboration, Materials Characterization, Mechanical Testing, Medical Devices Engineering, Microscopies, Professional Networking, Rheometry, Tensile Strength Testing, Tomography, X Ray Imaging. The role will naturally include substantial technical creative challenge for Device Characterization and more formal Design Verification, which includes development & validation of mechanical test methods as well as coordination & technical oversight for internal CPDA staff or external lab testing (where required) to meet project timelines and deliverables.
Associate Principal Scientist, Toxicology/Study Director Merck & Co IncAssociate Principal Scientist, Toxicology/Study DirectorWest Point, PA$142,400–$224,100 / yearRequired Skills: Animal Studies, Effective Written Communication, Evaluate Information, Good Laboratory Practices (GLPs), Oral Communications, Proactive Thinking, Study Directing, Study Monitoring, Teamwork, Toxicology. Our toxicologists provide scientific leadership in the design and overall conduct of in vivo studies and integrate the findings from all contributing scientists into reports that characterize the safety profile of drug candidates.
Sr. Principal Scientist, Nonclinical Drug Safety Merck & Co IncSr. Principal Scientist, Nonclinical Drug SafetyWest Point, PA$190,800–$300,300 / yearStrategically influence nonclinical drug safety considerations for Immunology programs by providing drug development mentorship and partnering with Compound Leaders on time-critical matters, including nonclinical program design and toxicology study design, weight-of-evidence risk assessments, science-based waiver strategies, and integrated safety development plans that support clinical trials, global registration, and timely resolution of nonclinical development issues. Provide scientific and strategic oversight for Immunology candidates through close collaboration with Program Coordinators, Discovery Preclinical Leaders, Compound Leaders, and scientists across NDS and/or Preclinical Development, while ensuring strong partnership with key Research and Development Division functions, including Discovery, chemistry, regulatory affairs, translational medicine, clinical development, and CMC.
Senior Principal Scientist, Veterinary Pathology Board Certified Merck & Co IncSenior Principal Scientist, Veterinary Pathology Board CertifiedWest Point, PA$231,900–$365,000 / yearRequired Skills: Analytical Assays, Analytical Assays, Assay Development, Biomedical Sciences, Biotechnology, Clinical Assays, Clinical Data Interpretation, Clinical Judgment, Clinical Safety, Drug Development, Drug Discovery Research, Drug Research, Histopathology, Immunochemistry, Immunology Research, Innovation, In Vitro Research, In Vivo Models, Laboratory Processes, Medical Biology, Molecular Diagnostic Techniques, Pathogenesis, Pharmaceutical Research, Post Mortem Analysis, Safety Pharmacology {+ 3 more}. Our Company's Research Laboratories nonclinical drug safety department at West Point, Pennsylvania site is seeking an experienced anatomic pathologist to join a highly collaborative team of scientists (12 anatomic pathologists, 3 clinical pathologists, and approximately 40 exceptional laboratory scientists), working at a GLP-compliant facility with state-of-the-art anatomic, molecular and clinical pathology laboratories.