VP/Principal, Services Business Development-USFI, Regionals Mastercard IncVP/Principal, Services Business Development-USFI, RegionalsBoston, MA$221,000–$349,000 / yearAll activities involving access to Mastercard assets, information, and networks comes with an inherent risk to the organization and, therefore, it is expected that every person working for, or on behalf of, Mastercard is responsible for information security and must: Abide by Mastercard's security policies and practices; Ensure the confidentiality and integrity of the information being accessed; Report any suspected information security violation or breach, and. By harnessing the power of our real-time, anonymized and aggregated transaction data, powerful software platforms and wealth of expertise, we empower customers to unlock a holistic view of consumer behavior beyond their four walls, distill actionable insights and make more data-driven decisions.
Principal Data Engineer Recorded Future IncPrincipal Data EngineerBoston, MA$152,000–$228,500 / yearWork with the Malicious Sites, Identity, and Surface Web teams to align, analyze, and ingest digital risk data streams into Digital Risk Protection systems and the Intelligence Graph. If you need any accommodation or special assistance to navigate our website or to complete your application, please send an e-mail with your request to our recruiting team at careers@recordedfuture.com.
Principal Program Manager, R&D PTC IncPrincipal Program Manager, R&DBoston, MAAs a Principal Program Manager, you will own end-to-end program execution for strategic initiatives, manage multi-product releases, and partner closely with Product and R&D leadership to define and optimize development processes, metrics, dashboards, and tooling. Today, we are a global team of nearly 7,000 and our main objective is to create opportunities for our team members to explore, learn, and grow - all while seeing their ideas come to life and celebrating the differences that make us who we are and the work we do possible.
Principal Scientist, Protein Production & Engineering Disc Medicine IncPrincipal Scientist, Protein Production & EngineeringMassachusetts, MA$166,000–$203,000 / yearPOSITION OVERVIEW: Disc Medicine is seeking a detailed-oriented and experienced protein biochemist who will join our Innovation team as a Principal Scientist/Associate Director reporting to our Senior Director, Protein production and engineering. This individual will lead the discovery, design, production and/or characterization of biologics at various discovery and development stages, effectively communicate project updates and contribute to the company portfolio with meaningful opportunities for professional development.
Senior Principal Scientist, Small Molecule Therapeutics Lila Sciences IncSenior Principal Scientist, Small Molecule TherapeuticsCambridge, MAThe ideal candidate is a highly experienced protein scientist and drug discovery leader who can operate strategically while remaining deeply engaged in experimental design, vendor selection, data interpretation, and cross-functional program execution. Oversee recombinant protein expression and purification efforts across external partners and CROs, including vendor selection, scope definition, protocol review, troubleshooting, quality assessment, and timeline management.
Principal Systems Security Engineer (Anti-Tamper / Program Protection) - P4 (Onsite) RTXPrincipal Systems Security Engineer (Anti-Tamper / Program Protection) - P4 (Onsite)Tewksbury, MassachusettsRaytheon is seeking a Principal Systems Security Engineer (Anti-Tamper/Program Protection) - P4 to join our elite Systems Security Engineering (SSE) team for the Systems Engineering and Test Capabilities discipline in developing solutions to protect the Warfighter’s technology advantage. Systems Security Engineering creates holistic security solutions leveraging Cybersecurity, Software Assurance, and Supply Chain Risk Management to support Program Protection on embedded weapons systems.
Principal Incident Manager Citizens Financial Group IncPrincipal Incident ManagerBoston, MA$120,000–$160,000 / yearThis role partners with technology, business, risk, architecture, and engineering teams to strengthen service stability, accelerate service restoration, improve operational performance, and reduce recurring issues within a highly regulated environment. The Principal Service Management Specialist provides strategic leadership across enterprise service management with a focus on incident management, operational resilience, governance, process maturity, and automation.
VP, Principal Quant Engineer Acadian Asset Management LLCVP, Principal Quant EngineerBoston, MA$185,000–$225,000 / yearIdentify opportunities to apply AI agents, automation, and modern infrastructure to improve quantitative research and development productivity and quality, including research pipeline tooling (signal development, efficacy evaluation/comparison) and model lifecycle management (model implementation, monitoring, deployment). Strong knowledge of modern architectural patterns, including Microservices and APIs, Event-driven and/or streaming architectures, Workflow orchestration and scheduling, Cloud infrastructure and containerization.
Principal Program Scheduler Axient LLCPrincipal Program SchedulerBedford, MABy enabling aircrews to electronically receive and process tasking orders, intelligence inputs, target coordinates, and mission‑critical flight and weapons data, MPS enhances combat effectiveness, increases sortie generation rates, and improves aircrew readiness and survivability across the Combat Air Forces (CAF) and Mobility Air Forces (MAF). In parallel with sustaining current mission planning capabilities, the Division is developing the next-generation Joint Mission Planning System Open Mission System (JOMS), a cloud‑based, micro‑service architecture designed to accelerate planning timelines, enhance collaboration, and deliver containerized services tailored to operational needs.
Senior Principal Semiconductor Equipment & Process Integration Engineer RTXSenior Principal Semiconductor Equipment & Process Integration EngineerMassachusettsThe candidate is expected to work well in large and small, cross-functional teams, understand foundry processes, determine process limitations, improve overall equipment effectiveness, identify throughput improvement opportunities, gather sponsorship and team resources, and execute activities. As an Equipment and Process Integration Engineer, you will collaborate across engineering work centers in our III-V semiconductor wafer foundry to manage the complete lifecycle of tool acquisitions—from planning through installation and sustainment.
NewAide/ESP - Algonquin Regional High School - Education Support Professional The Public Schools of Northborough And SouthboroughAide/ESP - Algonquin Regional High School - Education Support ProfessionalSouthborough, MAParticipate in a weekly meeting with the student support services team that includes data review, academic, social, and behavioral programming updates, and sharing of concerns. Skills, Knowledge and Ability: Skilled in implementing instructional and behavioral methods and procedures appropriate for the situation when learning or teaching new things.
Principal Software Engineer, Developer Acceleration Release Engineering HubSpot IncPrincipal Software Engineer, Developer Acceleration Release EngineeringCambridge, MA$266,200–$425,900 / yearThe Principal Software Engineer in Developer Acceleration will help determine how that platform evolves, how AI changes what''s possible in software delivery, and how thousands of engineers across HubSpot ship better software, faster. This is a rare opportunity to work on infrastructure problems that very few engineers have encountered - at a scale that demands novel approaches - while helping to define what AI-native release engineering looks like in practice.
Senior Principal Software Engineer/Architect UKG IncSenior Principal Software Engineer/ArchitectLowell, MA$207,400–$298,100 / yearM&A technical leadership: Lead technical diligence for acquisitions affecting Ready: evaluate architecture fit, identify integration risks (data, security, compliance), design migration/integration plans, and lead or advise post-close execution to minimize customer and delivery risk. Hands-on technical leadership: Own high-risk or high-impact technical work (POCs, performance optimizations, complex integrations), mentor architects and senior engineers, and lead architecture reviews and decision records.
C5I Principal Platform Engineer RTXC5I Principal Platform EngineerConcord, MassachusettsActive and existing security clearance required after day 1 At RTX, the world's largest aerospace and defense company, 185,000 great minds are united by purpose and inspired to make a difference solving the world’s most complex problems. This role requires deep DevSecOps expertise, technical leadership and the ability to influence architecture and engineering strategy across multiple teams.
Principal Clinical Trial Manager TransMedics Group IncPrincipal Clinical Trial ManagerAndover, MA$137,100–$193,700 / yearThis position is responsible for, but not limited to, the following: Leading the process of pre and post market clinical trials for FDA by employing effective organizational strategies and reviewing and presenting the results using rigorous clinical procedures. Experience in medical device (strongly preferred), Outstanding track record leading large complex global clinical trials for medical device products in different phases of the product cycle.
Principal Security Engineer - AI Seven AI IncPrincipal Security Engineer - AIBoston, MARequirements: 15+ years of experience in cybersecurity, including significant experience in SOC, Blue Team, Detection Engineering, Threat Hunting, or Incident Response roles, with strong experience in Security Orchestration, Automation, and Response (SOAR) platforms and security automation frameworks. Our Principal Security Engineers are at the forefront of the Agentic Security revolution - combining deep technical expertise with strategic leadership to help organizations modernize their security operations through intelligent automation.
Principal Technical Program Manager Lila Sciences IncPrincipal Technical Program ManagerCambridge, MAWe are introducing scientific superintelligence to solve humankinds greatest challenges, enabling scientists to bring forth solutions in human health, climate, and sustainability at a pace and scale never experienced before. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science's internal Talent Acquisition team.
Principal Program Quality Engineer BAE Systems PlcPrincipal Program Quality EngineerNashua, NHfor description visit the url https://jobs.baesystems.com/global/en/job/BAE1US125096BREXTERNAL/Principal-Program-Quality-Engineer .
Principal Business Consultant - SMB Lead Veeva Systems IncPrincipal Business Consultant - SMB LeadBoston, MA$120,000–$250,000 / yearExpertise: Deep domain knowledge in customer engagement strategy, sales and commercial operations, omnichannel, marketing excellence, key account management, and/or medical affairs are preferred and a comprehensive understanding of the Life Sciences landscape along with a passion for AI. As a Principal - Small Medium Business (SMB) Lead in our Commercial Practice, you will help customers bring treatments to patients faster by transforming how they capture and utilize Commercial Evidence, with Technology, Data, and AI.
Energy Regulations and Standards Senior Principal Engineer Dell Technologies IncEnergy Regulations and Standards Senior Principal EngineerHopkinton, MA$147,050–$190,300 / yearProvide strategic insight and leadership visibility by continuously assessing business and market factors related to energy programs-including competitive positioning, financial impact, portfolio considerations, risks, and timelines-and regularly reviewing strategy effectiveness with senior leadership. This role requires strong communication skills, technical credibility, and the ability to collaborate across a broad range of teams and stakeholders including engineers, product managers, executives, and external partners.