Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related) Amgen IncAssociate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related)Cambridge, MA$182,465–$246,865 / yearThe Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is seeking a highly motivated Computational Biologist with expertise in analyzing clinical biomarker data, including but not limited to metabolomics, genomics, transcriptomics, proteomics, spatial-omics, flow cytometry, immunoassays, and other biomarker assays. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity And Related) Amgen Inc.Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity And Related)Cambridge, MA$182,465–$246,865 / yearThe Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is seeking a highly motivated Computational Biologist with expertise in analyzing clinical biomarker data, including but not limited to metabolomics, genomics, transcriptomics, proteomics, spatial-omics, flow cytometry, immunoassays, and other biomarker assays. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Principal Scientist, Oligonucleotide PMO, ASO Development Dyne Therapeutics IncPrincipal Scientist, Oligonucleotide PMO, ASO DevelopmentWaltham, MA$159,000–$200,000 / yearThis role will ensure the delivery of robust, scalable, and cost-effective manufacturing processes, serve as the primary technical lead for external CDMOs, driving aggressive timelines while delivering well-characterized products optimized for our proprietary bioconjugation platform. Define Analytical Strategy: Support analytical development, focusing on robust impurity control strategies, raw material specifications, and comprehensive physicochemical characterization for both oligonucleotide payloads and conjugated protein drug substances.
Key Account Principal Clinical Specialist AbbottKey Account Principal Clinical SpecialistBoston, Massachusetts$86,700–$173,300 / yearThe Abbott Area Key Account Clinical Specialist will work in tandem with the sales team to grow Abbott’s market share in institutions that are critical to the long-term success of the EP division. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines.
Key Account Principal Clinical Specialist Abbott LaboratoriesKey Account Principal Clinical SpecialistBoston, MA$86,700–$173,300 / yearThe Abbott Area Key Account Clinical Specialist will work in tandem with the sales team to grow Abbott's market share in institutions that are critical to the long-term success of the EP division. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines.
Senior Medical Writer - clinical focus VeristatSenior Medical Writer - clinical focusMassachusettsFinal salary is ultimately decided upon taking into account a wide range of factors, including but not limited to: skills and experience, licensure and certifications, education, specific location and dynamic market data. Understand regulatory authority guidelines and requirements to be able to lead an internal project team and anticipate the effects that writing practice conventions can have on the final product when seeking health authority approval/acceptance.
Sr. Scientist/Principal Scientist, Translational Research and Clinical Biomarkers (Immunology) Antares TherapeuticsSr. Scientist/Principal Scientist, Translational Research and Clinical Biomarkers (Immunology)Boston, Massachusetts$160,000–$235,000 / yearCollaborate with teams across the organization, including clinical operations and data management, to ensure biomarker assay implementation and execution, and aid in the management of biomarker samples and data. The actual salary offered will be based on a number of factors, including but not limited to the qualifications of the applicant, years of relevant experience, level of education attained, certifications or other professional licenses held, and if applicable, the location in which the applicant lives and/or from which they will be performing the job.
Associate Medical Director, Clinical Science, NS TAU 3316 Takeda Development Center AmericasAssociate Medical Director, Clinical Science, NS TAUMassachusettsProvides leadership in meetings and negotiations with key opinion leaders, establishment of strategy for assigned compounds, and the direction of clinical scientists involved in developing documents required to outline the Company positions on research programs or regulatory applications (e.g. Contributes to the development and negotiation of clinical development plans for potential alliances and or in-licensing opportunities, interacts with upper management of potential partner/acquisition companies during DD visits and alliance negotiations and represents clinical science on internal assessment teams.
Sr. Director, Clinical Scientist Replimune Group, Inc.Sr. Director, Clinical ScientistWoburn, MA$256,500–$332,000 / yearThe Senior Director, Clinical Development/Clinical Scientist will report to the VP or Executive Director, of the Early Clinical Development team to ensure the successful execution of clinical development programs and deliverables in partnership across the organization, with external vendors, and with external academicians and collaboration partners. The RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response.
Senior Director of Clinical Science - Lung Merck & Co IncSenior Director of Clinical Science - LungBoston, MA$190,800–$300,300 / yearThe Senior Director partners closely with Section Heads, Asset Leads, Program Development Team Leads, and cross-functional development team members to support study planning, data interpretation, issue resolution, and broader program decisions across assigned studies and programs. The Senior Director, Clinical Science - Lung is responsible for providing strategic Clinical Science leadership across the lung disease area, with accountability spanning multiple studies, programs, and assets.
Director, Clinical Scientist Dyne TherapeuticsDirector, Clinical ScientistWaltham, MACompany Overview: Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duche...
Scientist/Senior Scientist, Assay Development - Neuroscience Biomarkers Spear Bio IncScientist/Senior Scientist, Assay Development - Neuroscience BiomarkersWoburn, MAProvide scientific leadership and translate biomarker biology into assay-design strategies by optimizing for clinically relevant molecular forms, isoforms, post-translational modifications, cleavage fragments, aggregation states, epitopes, and sample types. The successful candidate will help optimize assay strategies, identify the most relevant molecular forms and epitopes, evaluate preanalytical variables and matrix effects, interpret clinical-sample data, and troubleshoot complex assay-development challenges.
Senior Medical Writer- Clinical Focus VeristatSenior Medical Writer- Clinical FocusMassachusettsFinal salary is ultimately decided upon taking into account a wide range of factors, including but not limited to: skills and experience, licensure and certifications, education, specific location and dynamic market data. Understand regulatory authority guidelines and requirements to be able to lead an internal project team and anticipate the effects that writing practice conventions can have on the final product when seeking health authority approval/acceptance.
Senior Scientist In vivo Pharmacology & Translational Sciences, Cambridge, MA Isomorphic Labs LimitedSenior Scientist In vivo Pharmacology & Translational Sciences, Cambridge, MACambridge, MAProven track record managing multi-vendor CRO networks (including contract negotiation, timeline accountability, and data quality oversight) and the ability to lead and influence teams without direct authority, setting technical direction and driving execution across matrixed, externally-dependent programs. Act as a vital bridge between computational prediction and experimental reality, collaborating closely with: ML and Data Science Teams: To translate in silico predictions into physical validation protocols and provide clean data loops to train future models, iteratively improving the predictive accuracy of our proprietary drug design platform.
Sr. Scientist I/Sr. Scientist II, Applied AI & Agentic Systems for Drug Discovery Antares TherapeuticsSr. Scientist I/Sr. Scientist II, Applied AI & Agentic Systems for Drug DiscoveryBoston, Massachusetts$160,000–$220,000 / yearAs a member of a highly integrated team of medicinal chemists, chemical biologists, computational scientists, biologists, and machine learning scientists, you will develop and deploy LLM-driven agents for scientific workflows that shorten our design-make-test-analyze cycles and sharpen program decisions. Hands-on development and deployment of LLM-driven agents and multi-agent systems for scientific workflows, including MCP servers and tool integrations, using current agent frameworks and model-provider SDKs with frontier models (e.g., Claude, GPT).
Oligo Discovery Chemistry Principal Scientist GSK plcOligo Discovery Chemistry Principal ScientistCambridge, MA$121,275–$202,125 / yearThese responsibilities include some of the following: Establish pre-clinical oligonucleotide conjugation capabilities of ASOs, siRNA, SSO, and RNA editors with small molecules, lipids, linkers, and other conjugates with multistep synthesis from the milligram to gram scale. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success.
Associate Scientist / Scientist I, Computational Test Development Precede Biosciences IncAssociate Scientist / Scientist I, Computational Test DevelopmentBoston, MA$110,000–$150,000 / yearWe are pioneering an advanced, minimally invasive, comprehensive epigenomics platform with the potential to profoundly impact the research and development of new medicines and the use of approved medicines in clinical practice across a number of conditions, including cancer. MSc in computational biology, bioinformatics, biostatistics, or a closely related quantitative field with 3-4 years of industry or post-graduate research experience in a data-intensive biological or biomedical setting, Ph.
Executive Director, Clinical Science, Ophthalmology & Neuroscience Merck & Co IncExecutive Director, Clinical Science, Ophthalmology & NeuroscienceBoston, MA$255,800–$402,700 / yearRequired Skills: Advanced Analytics, Artificial Intelligence (AI), Clinical Development, Clinical Sciences, Cross-Functional Leadership, Drug Development, Executive Leadership, Global Clinical Studies, Innovation, Matrix Leadership, Neuroscience, Ophthalmology, Regulatory Submissions, Strategic Leadership, Talent Development. Partner withthe Ophthalmology and Neuroscience Therapeutic Area Heads and leaders across Clinical Operations, Regulatory Affairs, Biostatistics and Data Management, Drug Safety and Pharmacovigilance, Translational Medicine, and Medical Affairs to drive development strategy execution and delivery of key portfolio milestones.
Scientist/Senior Scientist, Assay Development - Molecular Assay Chemistry and Biophysics Spear Bio IncScientist/Senior Scientist, Assay Development - Molecular Assay Chemistry and BiophysicsWoburn, MATroubleshoot assay-performance issues, including low signal, nonspecific background, limited sensitivity, poor reproducibility, matrix effects, instability, and lot-to-lot variability, using a mechanistic understanding of binding kinetics, affinity, avidity, thermodynamics, steric effects, and molecular interactions. The Scientist / Senior Scientist will design, optimize, and troubleshoot innovative protein-detection assays that integrate antibody-based recognition, nucleic-acid interactions, conjugation chemistry, reaction kinetics, and quantitative analytical methods.
Medical Director, Clinical Development Prime MedicineMedical Director, Clinical DevelopmentCambridge, MAIn collaboration with research, clinical sciences, regulatory affairs and clinical operations, develop a clinical trials strategy for the efficient and safe introduction of Prime gene editing therapeutics into human study participants, through in-human proof-of-concept. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types.